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Addition of adrenaline to pethidine for epidural analgesia after Caesarean section (1997)_香港中文大学麻醉及深

香港中文大学 辅仁网/2017-06-20

Addition of adrenaline to pethidine for epidural analgesia after Caesarean section
Publication in refereed journal


香港中文大学研究人员 ( 现职)
许金山教授 (麻醉及深切治疗学系)
Professor Warwick Dean NGAN KEE (麻醉及深切治疗学系)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/3WOS source URL

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摘要We have investigated the addition of adrenaline to epidural pethidine for postoperative analgesia in 40 patients after Caesarean section. In a randomised, double-blind study, patients received pethidine 25 mg with adrenaline 50 mu g (adrenaline group, n = 20) or pethidine 25 mg without adrenaline (plain group, n = 18) epidurally at the first request for postoperative analgesia. The median duration of analgesia was longer in the adrenaline group (196 min; IQR 12http://aims.cuhk.edu.hk/converis/portal/Publication/3-286) compared with the plain group (96 min; IQR 4http://aims.cuhk.edu.hk/converis/portal/Publication/3-11http://aims.cuhk.edu.hk/converis/portal/Publication/3; p = 0.002) and plasma concentrations of pethidine in the first http://aims.cuhk.edu.hk/converis/portal/Publication/30 min after injection were lower in the adrenaline group (p = 0.00http://aims.cuhk.edu.hk/converis/portal/Publication/3). Visual analogue scale pain scores in the first http://aims.cuhk.edu.hk/converis/portal/Publication/30 min after injection and onset of analgesia, defined by the time for pain scores to decrease by 50%, were similar between groups. Addition of adrenaline to epidural pethidine has advantages for analgesia after Caesarean section.

着者Kee WDN, Ma ML, Khaw KS
期刊名称Anaesthesia
出版年份1997
月份9
日期1
卷号52
期次9
出版社BLACKWELL SCIENCE LTD
页次85http://aims.cuhk.edu.hk/converis/portal/Publication/3 - 857
国际标準期刊号000http://aims.cuhk.edu.hk/converis/portal/Publication/3-2409
电子国际标準期刊号1http://aims.cuhk.edu.hk/converis/portal/Publication/365-2044
语言英式英语

关键词anaesthetic techniques, epidural; analgesics, pethidine, meperidine; pain, postoperative; sympathetic nervous system, adrenaline, epinephrine
Web of Science 学科类别Anesthesiology; ANESTHESIOLOGY

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