Publication in refereed journal
香港中文大学研究人员 ( 现职)
| Professor Charles David GOMERSALL (麻醉及深切治疗学系) |
| Professor Gavin Matthew JOYNT (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1111/j.1365-2044.1997.173-az0307.x |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/16WOS source URL
其它资讯
摘要We prospectively investigated the effect of conventional resuscitation on gastric intramucosal pH and lactate over 5 days in a group of patients with newly diagnosed severe sepsis. Lactate and gastric intramucosal pH were measured on entry into the study, as soon as resuscitation end points were met, eight hourly for 48 h and daily for 5 days. Sixteen of 18 patients had a low gastric intramucosal pH (mean (SD) 7.17 (0.12)) at the time of diagnosis of severe sepsis. At no time did gastric intramucosal pH or lactate distinguish between shocked and nonshocked patients. Lactate distinguished survivors from nonsurvivors over time (p = 0.02). Gastric intramucosal pH did not distinguish survivors from nonsurvivors over time (p = 0.72). At 48 h lactate was lower in survivors (p < 0.01) and gastric intramucosal pH higher in survivors (p < 0.05). Receiver operating characteristic curves at this time indicate that lactate is a better predictor of survival. It is likely, based on the inability of gastric intramucosal pH to distinguish survivors from nonsurvivors until 48 h, that it is not possible to use this measurement to guide resuscitation in patients who are severely ill and who have gastric intramucosal acidosis.
着者Joynt GM, Lipman J, Gomersall CD, Tan I, Scribante J
期刊名称Anaesthesia
出版年份1997
月份8
日期1
卷号52
期次8
出版社BLACKWELL SCIENCE LTD
页次726 - 732
国际标準期刊号0003-2409
电子国际标準期刊号1365-2044
语言英式英语
关键词measurement techniques, gastric intramucosal pH; metabolism, lactate
Web of Science 学科类别Anesthesiology; ANESTHESIOLOGY
