Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 洪秀治教授 (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1097/00008506-199707000-00008 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/11WOS source URL
其它资讯
摘要This study evaluated the performance of a computer-controlled infusion (CCI) system for propofol during long neurosurgical procedures. Anesthesia was induced and maintained in 15 patients using a CCI of propofol. The initial target concentration was set at 3 mu g/ml, and this was then titrated according to the clinical situation. A total of 284 blood samples were taken for propofol assay. The performance of the system during anesthesia, assessed using the median performance error(MDPE), median absolute performance error (MDAPE), wobble, and divergence, were -5.3%, 20.6%, 9.0%, and 0.3%h, respectively. MDPE and MDAPE during the first: 20 min after stopping the infusion were -38.7% and 39.0%, respectively. The CCI system did not show significant changes in predictive ability, with time during anesthesia lasting up to 12 h. Changes in the measured blood concentration were in the same direction as changes in the target concentration.
着者Lim TA, Gin T, Tam YH, Aun CST, Short TG
期刊名称JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
出版年份1997
月份7
日期1
卷号9
期次3
出版社LIPPINCOTT-RAVEN PUBL
页次242 - 249
国际标準期刊号0898-4921
语言英式英语
关键词computer-controlled infusion; pharmacokinetics; propofol
Web of Science 学科类别Anesthesiology; ANESTHESIOLOGY; Clinical Neurology; CLINICAL NEUROLOGY; Neurosciences & Neurology; Surgery; SURGERY
