Genome-wide profiling of YY1 binding sites during skeletal myogenesis
Publication in refereed journal


香港中文大学研究人员 ( 现职)

孙昊教授 (化学病理学系)

王华婷教授 (李嘉诚健康科学研究所)

全文

数位物件识别号 (DOI) http://dx.doi.org/10.1016/j.gdata.2014.05.008

引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/0Scopus source URL

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摘要Skeletal muscle differentiation is regulated by a network of transcription factors, epigenetic regulators and noncoding RNAs. We have recently performed ChIP-seq experiments to explore the genome-wide binding of transcription factor YY1 in skeletal muscle cells. Our results identified thousands of YY1 binding peaks, underscoring its multifaceted functions in muscle cells. In particular, we identified a very high proportion of YY1 binding peaks residing in the intergenic regions, which led to the discovery of some novel lincRNAs under YY1 regulation. Here we describe the details of the ChIP-seq experiments and data analysis procedures associated with the study published by Lu et al. in the EMBO Journal in 2http://aims.cuhk.edu.hk/converis/portal/Publication/013 [1].

着者Sun K., Lu L., Wang H., Sun H.
期刊名称Genomics Data
出版年份2http://aims.cuhk.edu.hk/converis/portal/Publication/014
月份1
日期1
卷号2
出版社Elsevier Inc.
出版地United States
页次89 - 91
国际标準期刊号2213-596http://aims.cuhk.edu.hk/converis/portal/Publication/0
语言英式英语

关键词ChIP-seq, LincRNA, Myogenesis, YY1