Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 黄国柱教授 (外科学系) |
| 潘伟生教授 (外科学系) |
| 莫仲棠教授 (内科及药物治疗学系) |
| 谢珮珮女士 (化学病理学系) |
| 黎咏恩女士 (外科学系) |
| 陈秀雯教授 (精神科学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/j.jocn.2014.02.018 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/3WOS source URL
其它资讯
摘要Although aneurysmal subarachnoid hemorrhage (aSAH) accounts for only http://aims.cuhk.edu.hk/converis/portal/Publication/3-5% of all strokes, a high degree of morbidity has been reported in this relatively young subset of patients. Neuropsychiatric disturbance has often been neglected in these reports. We aimed to investigate the pattern and pathological factors of chronic neuropsychiatric disturbance in aSAH patients. This cross-sectional observational four-center study was carried out in Hong Kong. Neuropsychiatric outcome (Neuropsychiatric Inventory Chinese Version [CNPI]) assessments were conducted cross-sectionally 1-4 years after ictus. Pathological factors considered were early brain injury as assessed by admission World Federation of Neurosurgical Societies grade, aneurysm treatment (clipping versus coiling), delayed cerebral infarction, and chronic hydrocephalus. One hundred and three aSAH patients' spouses or caregivers completed the CNPI. Forty-two (41%) patients were reported to have one or more domain(s) of neuropsychiatric disturbance. Common neuropsychiatric disturbance domains included agitation/aggression, depression, apathy/indifference, irritability/lability, and appetite/eating disturbance. Chronic neuropsychiatric disturbance was associated with presence of chronic hydrocephalus. A subscore consisting of the five commonly affected domains seems to be a suitable tool for aSAH patients and should be further validated and replicated in future studies. (C) 2014 Elsevier Ltd. All rights reserved.
着者Wong GKC, Lam SW, Chan SSM, Lai M, Tse PPP, Mok V, Poon WS, Wong A
期刊名称Journal of Clinical Neuroscience
出版年份2014
月份10
日期1
卷号21
期次10
出版社Elsevier
页次1695 - 1698
国际标準期刊号0967-5868
电子国际标準期刊号15http://aims.cuhk.edu.hk/converis/portal/Publication/32-265http://aims.cuhk.edu.hk/converis/portal/Publication/3
语言英式英语
关键词Cerebral aneurysm; Neuropsychiatric disturbance; Stroke; Subarachnoid hemorrhage
Web of Science 学科类别Clinical Neurology; Neurosciences; Neurosciences & Neurology
