Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 赵慧君教授 (化学病理学系) |
| 卢煜明教授 (化学病理学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1196/annals.1318.022 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/17WOS source URL
其它资讯
摘要The detection of cell-free RNA in the plasma and serum of human subjects has opened up new investigational opportunities. Tumor-derived RNA was detected in the plasma and serum of patients with various forms of cancer. Through the development of robust extraction and quantification protocols for circulating RNA, new information regarding its biology and characteristics has been obtained. Plasma RNA was shown to be particle associated and to be surprisingly stable. Recently, fetal RNA was also demonstrated in maternal plasma. The placenta was shown to be an important source of such circulating fetal RNA. This discovery has created new prenatal diagnostic and monitoring possibilities. It is expected that circulating RNA will find application in many other clinical scenarios, including emergency medicine.
着者Lo YMD, Chiu RWK
会议名称3rd International Symposium on Circulating Nucleic Acids in Plasma/Serum (CNAPS III) and Serum Proteomics
会议开始日09.11.2003
会议完结日12.11.2003
会议地点Santa Monica
期刊名称Annals of the New York Academy of Sciences
出版年份2004
月份1
日期1
卷号1022
出版社NEW YORK ACAD SCIENCES
页次135 - 139
国际标準书号1-57331-551-6
国际标準期刊号0077-8923
电子国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/1749-6632
语言英式英语
关键词circulating RNA; plasma RNA; prenatal diagnosis
Web of Science 学科类别Biochemistry & Molecular Biology; Medical Laboratory Technology; Medicine, Research & Experimental; Multidisciplinary Sciences; Oncology; Research & Experimental Medicine; Science & Technology - Other Topics
