Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 霍泰辉教授 (儿科学系) |
| 林伟基教授 (化学病理学系) |
| 邓亮生教授 (化学病理学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/S0887-8994(02)00460-5 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/12WOS source URL
其它资讯
摘要Previous studies have demonstrated that carnitine levels were lower in patients taking valproate, especially in those who are younger than 24 months of age, those with concomitant neurologic or metabolic disorders, and those on multiple antiepileptic drugs. We performed a cross-sectional surveillance study on pediatric patients taking valproate to evaluate the relationship between carnitine levels and demographic data including age, daily dosage of valproate, number of antiepileptic drugs, body mass index, and feeding problems. Among the 43 patients studied, only two patients were found to have carnitine levels below the normal limit. There were no statistically significant associations between carnitine levels and age, body mass index, additional antiepileptic drugs used, presence of mental retardation, cerebral palsy, or feeding problems, nonambulatory status, or dosage of valproate. We conclude that routine carnitine level checking is not justified in pediatric patients taking valproate. (C) 2003 by Elsevier Science Inc. All rights reserved.
着者Fung ELW, Tang NLS, Ho CS, Lam CWK, Fok TF
期刊名称Pediatric Neurology
出版年份2003
月份1
日期1
卷号28
期次1
出版社ELSEVIER SCIENCE INC
页次24 - 27
国际标準期刊号0887-8994
语言英式英语
Web of Science 学科类别Clinical Neurology; CLINICAL NEUROLOGY; Neurosciences & Neurology; Pediatrics; PEDIATRICS
