Publication in refereed journal
香港中文大学研究人员 ( 现职)
| Professor Clive Stewart COCKRAM (内科及药物治疗学系) |
| 崔耀隆教授 (化学病理学系) |
| 杨铎辉教授 (内科及药物治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1097/00001756-199607290-00002 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/7WOS source URL
其它资讯
摘要C-TYPE natriuretic peptide (CNP), a third member of the natriuretic peptide family, is found throughout the central nervous system (CNS), particularly in those regions involved in neuroendocrine regulation. Astrocytes, which have important physiological roles in normal neuronal functioning, express receptors of CNP. Using reverse transcription-polymerase chain reaction (RT-PCR), followed by hybridization with a digoxigenin-labelled cDNA probe, we have demonstrated the expression of CNP gene transcripts in both cultured mouse astrocytes and rat C6 glioma cells, with the former expressing the gene at a considerably higher level than the latter. Our data raise the possibility that CNP may act in autocrine and/or paracrine fashion in glial cell physiology and neuromodulate communication between glial cells and neurones.
着者Yeung VTF, Mak ASC, Chui YL, Ho SKS, Lai KN, Nicholls MG, Cockram CS
期刊名称NEUROREPORT
出版年份1996
月份http://aims.cuhk.edu.hk/converis/portal/Publication/7
日期29
卷号http://aims.cuhk.edu.hk/converis/portal/Publication/7
期次11
出版社RAPID SCIENCE PUBLISHERS
页次1http://aims.cuhk.edu.hk/converis/portal/Publication/709 - 1http://aims.cuhk.edu.hk/converis/portal/Publication/712
国际标準期刊号0959-4965
电子国际标準期刊号14http://aims.cuhk.edu.hk/converis/portal/Publication/73-558X
语言英式英语
关键词astrocytes; C-type natriuretic peptide; C6 glioma; mRNA expression
Web of Science 学科类别Neurosciences; NEUROSCIENCES; Neurosciences & Neurology
