Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 何宗信教授 (化学病理学系) |
| 陈恩强教授 (内科及药物治疗学系) |
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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/11WOS source URL
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摘要In this retrospective study, we evaluated the clinical value of screening for salicylates in 347 patients with acute poisoning presenting to the Prince of Wales Hospital, Hong Kong, between January 1992 and June 1993 in 83 patients (24%), ingestion of salicylates was suspected; the incidence of elevated plasma salicylate concentrations (>0.1 mmol/L) in those who had taken identifiable drugs, unidentifiable drugs but known type, or topical medicaments was 71%, 16% and 61%, respectively. In 264 patients (76%), ingestion of salicylates was not suspected, and of these, 3 had elevated (0.2-0.4 mmol/L) plasma salicylate concentrations. Routine screening for salicylates in all patients with acute poisoning in Hong Kong appears unnecessary, especially as many authorities consider that 1 of the main indications for treating salicylate poisoning is clinical evidence of toxicity. Restricting plasma measurements to only those suspected of having ingested salicylates would have saved up to 76% of requests. All physicians should be aware of the high salicylate content of some Chinese proprietary topical medicaments.
着者CHAN TYK, CHAN AYW, HO CS, CRITCHLEY JAJH
期刊名称VETERINARY AND HUMAN TOXICOLOGY
出版年份1995
月份2
日期1
卷号37
期次1
出版社COMPARATIVE TOXICOLOGY LAB KANSAS STATE UNIV
页次37 - 38
国际标準期刊号0145-6296
语言英式英语
Web of Science 学科类别Toxicology; Veterinary Sciences
