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FOLATE CONCENTRATION IN CHINESE PSYCHIATRIC OUTPATIENTS ON LONG-TERM LITHIUM TREATMENT (1992)_香港中文大学

香港中文大学 辅仁网/2017-06-20

FOLATE CONCENTRATION IN CHINESE PSYCHIATRIC OUTPATIENTS ON LONG-TERM LITHIUM TREATMENT
Publication in refereed journal


香港中文大学研究人员 ( 现职)
荣润国教授 (精神科学系)
陈佳鼐教授 (精神科学系)
石志忠教授 (化学病理学系)
周振中教授
李诚教授 (精神科学系)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/11WOS source URL

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摘要Among 46 Chinese and mostly manic-depressive (85%) outpatients attending a lithium clinic in Hong Kong, virtually no patients had low serum (0%) or erythrocyte (2%) folate. Their mean folate levels did not differ from lithium-free outpatients. Although serum folate correlated negatively with lithium dose (P < 0.002) and serum level (P < 0.01), lithium treatment probably did not by itself cause low folate. Folate level was not related to diagnosis, duration of mental illness, other drug usage or spot affective morbidity. Patients with a good response to lithium in the previous one year had a higher mean serum folate level than those with unsatisfactory response (P < 0.05). These data suggest that folate deficiency is uncommon among Chinese psychiatric outpatients, but support recent evidence that folate at high concentrations enhances lithium prophylaxis.

着者LEE S, CHOW CC, SHEK CC, WING YK, CHEN CN
期刊名称Journal of Affective Disorders
出版年份1992
月份4
日期1
卷号24
期次4
出版社ELSEVIER SCIENCE BV
页次265 - 270
国际标準期刊号0165-0327
电子国际标準期刊号1573-2517
语言英式英语

关键词CHINESE; FOLATE; LITHIUM
Web of Science 学科类别Clinical Neurology; CLINICAL NEUROLOGY; Neurosciences & Neurology; Psychiatry; PSYCHIATRY, SCI; PSYCHIATRY, SSCI

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