Dr. XU, Chenjie
PhD (Brown University), M.S. (HKUST), B.S. (Nanjing University)
Associate Professor
Research Interest Nanomedicine
Transdermal drug delivery
Transdermal biosensing
Nucleic acid nanotechnology
Microneedles


Phone: +852 3442-4169
Email: chenjie.xu@cityu.edu.hk

Address: YEUNG-P7719
Web: Personal Homepage



BIOGRAPHY
Dr. Xu is dedicated to develop novel engineering solutions for addressing the unmet in the field of medicine. Specifically, he focuses on the application of nanotechnology to medicine (or nanomedicine), which has potentials for shifting paradigms in medicine encompassing diagnosis, imaging, surgery, and drug administration. In the past 10 years, the key innovations stemming from the laboratory include microneedle-based skin patch and nucleic acid-based nanoparticles (molecular beacon, Spherical Nucleic Acids and DNA origami) for the delivery of sensors and therapeutics. He has published more than 100 scientific articles with >10,000 citation and H-index of 41 (by Dec 8th 2019). He also filed 10 patent applications and edited two books.



EDUCATION
2012 Postdoc Bioengineering, Brigham and Women's Hospital, USA
2009 Ph.D. Chemistry, Brown University, USA
2004 M.Phil. Chemistry, Hong Kong University of Science & Technology, Hong Kong
2002 B.S. Chemistry, Nanjing University, China




AWARDS
2019 Poster Award from Nano Letters, 17th International Nanomedicine & Drug Delivery Symposium, Cambridge, Massachusetts, USA
2019 Tan Chin Tuan Exchange Fellowship in Engineering, Nanyang Technological University, Singapore
2009 Joukowsky Outstanding Dissertation Prize Brown University, USA
2009 Potter Prize for Outstanding Doctoral Thesis Brown University, USA
2007 Vince Wernig Fellowship, Brown University, USA




SELECTED PUBLICATIONS
Christian Wiraja, Maria Esterlita Siantoputri, Sihan Liu, Ho Cheung Shum, Chenjie Xu. Unraveling Framework Nucleic Acid - Skin Cell Interactions with a Co-culture System. Advanced Biosystems, 2020, DOI:10.1002/adbi.201900169 (cover)
Christian Wiraja, Ying Zhu, Daniel Lio, David C. Yeo, Mo Xie, Weina Fang, Qian Li, Mengjia Zheng, Maurice Van Steensel, Lihua Wang, Chunhai Fan, Chenjie Xu. Framework Nucleic Acids as Programmable Carrier for Transdermal Drug Delivery. Nature Communication, 2019, 10, 1147
Mengjia Zheng, Christian Wiraja, David C Yeo, Hao Chang, Daniel Chin Shiuan Lio, Kanyi Pu, Amy S. Paller, Chenjie Xu, Oligonucleotide molecular sprinkler for intracellular detection and spontaneous regulation of mRNA for theranostics of scar fibroblasts. Small, 2018, 14(49), 1802546.
David C. Yeo, Christian Wiraja, Amy S. Paller, Chad A. Mirkin, Chenjie Xu. Abnormal Scar Identification with Spherical Nucleic Acids Technology, Nature Biomedical Engineering, 2018, 2, 227-238
Min Wang, Yiyuan Han, Xiaojun Yu, Liangliang Liang, David Yeo, Mei Ling Wee, Linbo Liu, Xiaogang Liu, Chenjie Xu. Upconversion Nanoparticle Powered Microneedle Patches for Transdermal Delivery of siRNA. Advanced Healthcare Materials, 2019, DOI: 10.1002/adhm.201900635
Aung Than, Chenghao Liu, Hao Chang, Phan Khanh Duong, Xiaomeng Wang, Chenjie Xu, Peng Chen. Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery, Nature Communication, 2018, 9, 4433
Phoebe Tham Huijun, Keming Xu, Wei Qi Lim, Hongzhong Chen, Steven Thng Tien Guan, Subbu S. Venkatraman, Chenjie Xu, Yanli Zhao. Microneedle-Assisted Topical Delivery of Photodynamically Active Mesoporous Formulation for Combination Therapy of Deep-Seated Melanoma. ACS Nano. 2018, 12, 11936-11948
Hao Chang, Mengjia Zheng, Xiaojun Yu, Aung Than, Razina Z. Seeni, Rongjie Kang, Jingqi Tian, Duong Phan Khanh, Linbo Liu, Peng Chen, Chenjie Xu. A swellable microneedle patch to rapidly extract skin interstitial fluid for timely metabolic analysis. Advanced Materials. 2017, 29 (37), 1702243




Last modified on 21 May, 2020