Dr. LAI, W. C., King
BEng(CUHK), MPhil(CUHK), PhD(CUHK)
Associate Professor
Research Interest Scanning probe microscopy
Micro-/nano-manipulation
Nano electronics and devices
Photovoltaics
Bio-nanotechnology


Phone: +852 3442-9099
Email: kinglai@cityu.edu.hk

Address: YEUNG-P6417
Web: Personal Homepage



EDUCATION & EXPERIENCE
2006 - 2012 Postdoctoral Researcher Electrical and Computer Engineering Michigan State University
2002 - 2005 Ph.D. Automation and Computer-Aided Engineering Chinese University of Hong Kong
2000 - 2002 M.Phil. Automation and Computer-Aided Engineering Chinese University of Hong Kong
1997 - 2000 B.Eng. Mechanical and Automation Engineering Chinese University of Hong Kong




AWARDS
2019 Best Poster Award, The 19th IEEE International Conference on Nanotechnology (IEEE-Nano)
2017 Second Prize (Construction Safety), CIC Construction Innovation Award
2017 Student Research Award 2016-2017 from the Hong Kong Medical and Healthcare Device Industries Association (HKMHDIA) (PhD Student: Guangfu Wu)
2017/2018 Outstanding Academic Performance Award for Research Degree Students (PhD Student: Qi Gao)
2017 Best Engineering Design Award, Best Artistic Design Award, and Best Team Spirit Award from the Robocon 2017 - Hong Kong Contest (UG Student: Robocon team)
2016 Teaching Excellent Award, City University of Hong Kong
2016/2017 Outstanding Academic Performance Award for Research Degree Students (PhD Student: Xin Tang)
2014 Silver Award at the HKEIA Innovation & Technology Project Competition
2013/2014 Outstanding Academic Performance Award for Research Degree Students (PhD Student: Yuqiang Fang)
2013 Best Conference Paper Award, the 13th IEEE International Conference on Nanotechnology (IEEE-Nano)
2010 Best Conference Paper Award, the 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS)
2004 Best Conference Paper Award, International Conference on Intelligent Mechatronics and Automation (ICIMA)
2000 Best Student Paper Award, International Conference on Information Society in the 21st Century (IS2000)



PUBLICATIONS
2019-20: Xiaoting Li and King Wai Chiu Lai, "Highly Flexible and Stretchable Structure Based on Au/Graphene Film and Polyurethane Yarn
Identification of energy landscape of Sp1 zinc-finger in Pb(II) or Cd(II) using AFM
Dynamic effect of beta-amyloid 42 on cell mechanics
Facile Construction of DNA Tetrahedron in Unconventional Ladder-Like Arrangements at Room Temperature
Computational Modeling of Cell Adhesion under the Effect of Substrate Stiffness," IEEE Transactions on Nanotechnology, vol. 17, pp. 402 – 406, May, 2018. DOI: 10.1109/TNANO.2017.2767036.
Guangfu Wu, M. Meyyappan and King Wai Chiu Lai, “Simulation of Graphene Field-Effect Transistor Biosensors for Bacterial Detection,” Sensor, vol. 18, pp. 1715, May, 2018. doi:10.3390/s18061715.
Qi Gao, Yuqiang Fang, Shiqing Zhang, Hung-Wing Li, Ken K. L. Yung and King Wai Chiu Lai, “Biophysical Characteristics of Human Neuroblastoma Cell in Oligomeric β-amyloid (1-40) Cytotoxicity,” IEEE Transactions on NanoBioscience, vol. 17, pp. 70-77, 2018. DOI: 10.1109/TNB.2018.2800723.
Guangfu Wu, Xin Tang, M. Meyyappan, and King Wai Chiu Lai, “Doping Effects of Surface Functionalization on Graphene with Aromatic Molecule and Organic Solvents,” Applied Surface Science, vol. 425, pp. 713-721, Dec, 2017.
Guangfu Wu, Ziwen Dai, Xin Tang, Zihong Lin, Pik Kwan Lo, Meyya Meyyappan and King Wai Chiu Lai, "Graphene Field-Effect Transistors for the Sensitive and Selective Detection of Escherichia coli Using Pyrene-Tagged DNA Aptamer," Advanced Healthcare Materials, vol 6, 1700736, DOI: 10.1002/adhm.201700736, 2017. (Inside Front Cover)
Xudong Lin, Ying Wang, Xian Chen, Runhuai Yang, Zixun Wang, Jingyu Feng, Haitao Wang, King W. C. Lai, Jufang He, Feng Wang, Peng Shi, “Multiplexed Optogenetic Stimulation of Neurons with Spectrum-Selective Upconversion Nanoparticles,” Advanced Healthcare Materials, vol 6, 1770090, DOI: 10.1002/adhm.201700446, 2017.
Florence Hiu Ling Chan, Runhuai Yang and King Wai Chiu Lai, "Development of the Electric Equivalent Model for the Cytoplasmic Microinjection of Small Adherent Cells," Micromachines, vol. 8(7), 216, DOI:10.3390/mi8070216, 2017.
Before 2017: Xin Tang, Guangfu Wu, and King Wai Chiu Lai, "Twisted Graphene-assisted Photocarrier Transfer from HgSe Colloidal Quantum Dots into Silicon with Enhanced Collection and Transport Efficiency,” Applied Physics Letters, vol. 110, pp. 241104, DOI: 10.1063/1.4986188, 2017.
Xin Tang, Guangfu Wu, and King Wai Chiu Lai, "Plasmon Resonance Enhanced Colloidal HgSe Quantum Dots Filterless Narrowband Photodetectors for Mid-wave Infrared,” RSC Journal of Materials Chemistry C, vol. 5, pp. 362-369, DOI: 10.1039/C6TC04248A, 2017.
Runhuai Yang, Yuqiang Fang, Jie Yang, and King W. C. Lai, "Design and Analysis of Electrical Resistance Feedback for Automated Patch Clamp on Adherent Cells, IEEE Transactions on Automation Science and Engineering, vol. 14, pp. 844-854, 2017.
Guangfu Wu, Xin Tang, Wengang Ji, Wai Chiu King Lai, and Qingxiao Tong, "A turn-on fluorescent probe based on coumarin-anhydride for highly sensitive detection of hydrazine in the aqueous solution and gas states," Methods and Applications in Fluorescence, vol. 5, p. 1-7, 2017.
Xin Tang, Xiaobing Tang, and King Wai Chiu Lai, “Scalable Fabrication of Infrared Detectors with Multi-spectral Photoresponse based on Patterned Colloidal Quantum-dot Films,” ACS Photonics, vol. 3, pp. 2396-2404, DOI: 10.1021/acsphotonics.6b00620, 2016.
Ziwen Dai, Qi Gao, Man Ching Cheung, Hoi Man Leung, Terrence Chi Kong Lau, Hanadi F. Sleiman, King Wai Chiu Lai**, and Pik Kwan Lo**, “A Highly Versatile Platform Based on Geometrically Well-Defined 3D DNA Nanostructures for Selective Recognition and Positioning of Multiplex Targets,” RSC Nanoscale, vol. 8, pp. 18291-18295, 2016. (**corresponding author)
Guangfu Wu, Mingxin Li, Jieji Zhu, King Wai Chiu Lai, Qing-xiao Tong, and Feng Lu “A Highly Sensitive and Selective Turn-on Fluorescent Probe for Pb(II) ion based on Coumarin-quinoline Platform,” RSC Advances, vol. 6, no. 10, pp. 100696-100699, 2016.
Xin Tang, Hengkai Zhang, Xiaobing Tang, and King W. C. Lai, "Photoresponse enhancement in graphene/silicon infrared detector by controlling photocarrier collection," Materials Research Express, vol. 3, no. 7, 076203, 2016.
Xin Tang, King W. C. Lai, “Substrate Effect on Atomic Force Microscopy (AFM) based Nanolithography of Graphene,” IEEE Transaction on Nanotechnology, 2016, vol. 15, no. 4, pp.607-613, 2016.
Yuqiang Fang, King W. C. Lai, “Modelling the mechanics of cells in the cell spreading process driven by traction forces,” Physical Review E, vol. 93, 042404, 2016.
Sheng B, Xiao Zeng, Xin Tang, Shujia Qin and King W. C. Lai, “Compressive Video Recovery Using Block Match Multi-Frame Motion Estimation Based on Single Pixel Cameras,” Sensors, vol. 16(3), 318; doi:10.3390/s16030318, 2016.
Ruiguo Yang, Bo Song, Zhiyong Sun, King Wai Chiu Lai, Carmen Kar Man Fung, Kevin C. Patterson, Kristina Seiffert-Sinha, Animesh A. Sinha, Ning Xi, “Cellular level robotic surgery: Nanodissection of intermediate filaments in live keratinocytes,” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 11(1), pp.137-145, 2015.
Y. Fang, C. Y. Y. Iu, C. N. P. Lui, Y. Zou, C. K. M. Fung, H. W. Li, N. Xi, K. K. L. Yung** and King W. C. Lai**, “Investigating dynamic structural and mechanical changes of neuroblastoma cells associated with glutamate-mediated neurodegeneration”, Scientific Reports, vol. 4, 7074, DOI:10.1038/srep07074, 2014. (**corresponding author)
Runhuai Yang, Chi Ho Tam, Ka Lun Cheung, Kai Chun Wong, Ning Xi, Jie Yang, and King W. C. Lai, “Cell Segmentation and Pipette Identification for Automated Patch Clamp Recording,” Robotics and Biomimetics, vol. 1, 20, 2014.
Kristina Seiffert-Sinha, Ruiguo Yang, Carmen K. Fung, King W. C. Lai, Kevin C. Patterson, Aimee S. Payne, Ning Xi and Animesh A. Sinha, “Nanorobotic Investigation Identifies Novel Visual, Structural and Functional Correlates of Autoimmune Pathology in a Blistering Skin Disease Model”, PLoS ONE, 9(9), e106895.doi:10.1371/journal.pone.0106895, 2014.
N. P. B. Au+, Y. Fang+, N. Xi, K. W. C. Lai*, and C. H. E. Ma*, “Probing for chemotherapy-induced peripheral neuropathy in live dorsal root ganglion neurons with atomic force microscopy,” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 10, pp. 1323–1333, 2014. (+contributed equally and **corresponding author)
King Wai Chiu Lai, Ning Xi, Hongzhi Chen, Bo Song, and Liangliang Chen, Development of Infrared Camera Using Graphene, IEEE Nanotechnology Magazine, vol. 6, issue 1, pp. 4-7, 2012.
Hongzhi Chen, Ning Xi, King Wai Chiu Lai, Liangliang Chen, Ruiguo Yang, and Bo Song, Gate dependent photo-responses of carbon nanotube field effect phototransistors, Nanotechnology, vol. 23, pp. 385203, 2012.
Hongzhi Chen, Ning Xi, King Wai Chiu Lai, Liangliang Chen, Carmen Kar Man Fung, and Jianyong Lou, Plasmonic-resonant bowtie antenna for carbon nanotube photodetectors, International Journal of Optics, vol. 2012, pp. 318104 (9 pages), 2012.
Ruiguo Yang, Jennifer Y. Chen, Ning Xi, King Wai Chiu Lai, Chengeng Qu, Carmen Kar Man Fung, Lynn S. Penn, and Jun Xi, Characterization of mechanical behavior of an epithelial monolayer in response to epidermal growth factor stimulation, Experimental Cell Research, vol. 318, issue 5, pp. 521-526, 2012.
Ning Xi and King Wai Chiu Lai, (2011), Nano-Optoelectronic Devices and Sensors: Nanophotonics from Design to Manufacturing, Elsevier Limited, UK. (order at Amazon)
Ruiguo Yang, Ning Xi, Carmen Kar Man Fung, Kristina Seiffert-Sinha, King Wai Chiu Lai, and Animesh A. Sinha, The Emergence of AFM Applications to Cell Biology: How new technologies are facilitating investigation of human cells in health and disease at the nanoscale, Journal of Nanoscience Letters, vol.1, No. 2, pp. 87-101, 2011.
Ruiguo Yang, Ning Xi, King Wai Chiu Lai, Beihua Zhong, Carmen Kar Man Fung, Chengeng Qu, and Donna H. Wang, Nanomechanical Analysis of Insulinoma Cells by Atomic Force Microscopy after Glucose and Capsaicin Stimulation, Acta Pharmacologica Sinica, vol. 32, pp. 853-860, 2011.
Carmen Kar Man Fung, Ning Xi, Ruiguo Yang, Kristina Seiffert-Sinha, King Wai Chiu Lai, and Animesh A. Sinha, Quantitative Analysis of Human Keratinocyte Cell Elasticity using Atomic Force Microscopy (AFM), IEEE Transactions on Nanobioscience, vol. 10, issue 1, pp. 9-15, 2011.
King Wai Chiu Lai, Jeffri J. Narendra, Ning Xi, Jiangbo Zhang, Timothy A. Grotjohn and Jes Asmussen, Development of Plasma Nanomanufacturing Workcell, Journal of Manufacturing Science and Engineering, vol. 132, issue 3, pp. 031003 (8 pages), 2010.
Carmen Kar Man Fung, Ruiguo Yang, King Wai Chiu Lai, Ning Xi, K Seiffert-Sinha, AA Sinha, Micro fixture enabled in-situ imaging and manipulation of cell membrane protein, 2010 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), pp. 165-168, 2010. (Best Conference Paper)
Carmen Kar Man Fung, Ning Xi, King Wai Chiu Lai, Jianyong Lou, and Hongzhi Chen, Noncryogenic, Cooled IR Sensors Based on Carbon Nanotubes, SPIE Newsroom, doi: 10.1117/2.1201011.003294, 2010.
Hongzhi Chen, Ning Xi, King W. C. Lai, Carmen Kar Man Fung and Ruiguo Yang, Development of High Performance Infrared Detector Using Carbon Nanotube Field Effect Transistors, IEEE Transactions on Nanotechnology, vol. 9, no. 5, pp. 582-589, 2010.
Ning Xi, Carmen K. M. Fung, Ruiguo Yang, Kristina Seiffert-Sinha, King Wai Chiu Lai, and Animesh A. Sinha, Bionanomanipulation using atomic force microscopy - Understanding disease at the molecular level using a nano robot, IEEE Nanotechnology Magazine, vol. 4, no. 1, pp. 9-12, 2010.
Carmen K. M. Fung, Seiffert-Sinha, King W. C. Lai, R. Yang, D. Panyard, J. Zhang, N. Xi and A. Sinha, Investigation of human keratinocyte cell adhesion using atomic force microscopy (AFM), Nanomedicine, vol. 6, issue 1, pp. 191-200, 2010.
King W. C. Lai, Ning Xi, Carmen K. M. Fung, Hongzhi Chen and Tzyh-Jong Tarn, Engineering the Band Gap of Carbon Nanotubes for Infrared Sensors, Applied Physics Letters, vol. 95, issue 22, 221107, 2009.
Carmen K. M. Fung, Ning Xi, Balasubramaniam Shanker, King W. C. Lai, Nano Resonant Signal Booster for Carbon Nanotube Based Infrared Detectors, Nanotechnology, vol. 20, 185201, 2009.
King W. C. Lai, Ning Xi, Carmen Kar Man Fung, Jiangbo Zhang, Hongzhi Chen, Yilun Luo and Uchechukwu C. Wejinya, Automated Nanomanufacturing System to Assemble Carbon Nanotube Based Devices, The International Journal of Robotics Research (IJRR), vol. 28, issue 4, pp. 523-536, 2009.
Jiangbo Zhang, Ning Xi, Hongzhi Chen, King W. C. Lai, and Guangyong Li, Design, Manufacturing and Testing of Single Carbon Nanotube Based Infrared Sensors, IEEE Transactions on Nanotechnology, vol. 8, issue 2, pp. 245-251, 2009.
King W. C. Lai, Ning Xi, Uchechukwu C. Wejinya, Automated Process for Selection of Carbon Nanotube by Electronic Property using Dielectrophoretic Manipulation, Journal of Micro-Nano Mechatronics, vol. 4, issue 1, pp. 37-48, 2008.
Uchechukwu C. Wejinyaa, Yantao Shen, Ning Xi, King W. C. Lai and Jiangbo Zhang, An efficient approach of handling and deposition of micro and nano entities using sensorized microfluidic end-effector system, Sensors and Actuators A: Physical, vol. 147, issue 1, pp. 6-16, 2008.
Jiangbo Zhang, Ning Xi, Hongzhi Chen, King W. C. Lai, Guangyong Li, Photovoltaic Effect in Single Carbon Nanotube Based Schottky Diodes, International Journal of Nanoparticles, vol. 1, no. 2, pp. 108-118, 2008.
Jiangbo Zhang, Ning Xi, Lianqing Liu, Hongzhi Chen, King W. C. Lai, and Guangyong Li, Atomic force yields a master nanomanipulator, IEEE Nanotechnology Magazine, vol. 2, no. 2, pp. 13-17, 2008.
Jiangbo Zhang, Ning Xi and King Lai, Fabrication and Testing of a Nano Infrared Detector Using a Single Carbon Nanotube (CNT), SPIE Newsroom, doi: 10.1117/2.1200701.0514, 2007.
King W. C. Lai, Carmen K. M. Fung, Victor T. S. Wong, Mandy L. Y. Sin, Wen J. Li and C. P. Kwong, Development of an Automated Microspotting System for Rapid Dielectrophoretic Fabrication of Bundled Carbon Nanotube Sensors, IEEE Transactions on Automation Science and Engineering, vol. 3, no. 3, pp. 218-227, 2006.
King W. C. Lai, PS Chung, Ming Li, Wen J Li, Automated micro-assembly of surface MEMS mirrors by centrifugal force, IEEE International Conference on Mechatronics and Automation, pp. 26-31, 2004. (Best Conference Paper)
King W. C. Lai, Carmen KM Fung, Wen J Li, Imad Elhajj, Ning Xi, Transmission of multimedia information on micro environment via internet,. 26th Annual Conference of the IEEE Industrial Electronics Society, 2000 (IECON 2000), vol. 3, pp. 1913-1918, 2000. (Best Student Paper)





*** Recruitment/Openings *** Looking for enthusiastic graduate students, research assistants and undergraduate researchers to perform research in the followings areas:
Nano-robotics and nano-manipulation
Design and fabrication of optical sensor
Mechatronic design
Interested applicants please send your CV to kinglai@cityu.edu.hk
Last modified on 2 October, 2019