黄军就

Submitted on 周一, 10/30/2017 - 20:22


性别
男

工作电话


电子邮件
hjunjiu@mail.sysu.edu.cn

职称
教授

导师类型
博士生导师

学历
理学博士

学科方向
0710生物学-10生物化学与分子生物学


研究方向
1.细胞衰老和再生的调控机制
2.细胞基因编辑技术研究与应用
3.哺乳动物胚胎早期发育机制研究

个人经历
教育经历：
2004.09-2009.07??? 中山大学 ，细胞生物学，博士毕业，导师：刘林 （国家****，“973项目首席科学家”）
2007.09-2009.05??? University of South Florida ，生殖医学，第一届“国家建设高水平大学公派项目”联合培养博士，导师：David L. Keefe（美国生殖学学会副主席）
2000.09-2004.07??? 中山大学，生物技术专业 ，本科毕业??
1994.09-2000.06???? 江门市第一中学，高中
?
工作经历：
2017.07-至今????????? 中山大学??????? 生命科学学院，副院长
2016.06-至今????????? 中山大学??????? 生命科学学院教授，博士生导师
2016.10-2017.07????? 中山大学??????? 生命科学学院，院长助理
2011.12-2016.06?? ???中山大学??????? 副教授
2011.08-2011.11??? ??中山大学??????? 讲师
2009.08-2011.07???? 中山大学???? ?师资博士后（讲师）

讲授课程
本科生必修课：《遗传学实验》、《新生研讨课》；本科生选修课：《现代生物技术进展》
研究生选修课：《干细胞与细胞分化》
2013年，指导本科生实验队SYSU-China获得国际基因工程机器设计大赛（iGEM）亚洲区金牌， “最佳模型”（Best Model）和“最佳原生基因组件奖”（Best New BioBrick Part, Natural）两单项特别大奖；全球决赛获得全程金奖（FINALISTS）第三名，为本年度亚洲地区唯一获得世界赛大奖的高校队伍，此外还获得最佳网页奖（Best Wiki）单项特别大奖。
2014年，指导本科生实验队SYSU-China获得国际基因工程机器设计大赛（iGEM）全球铜牌以及亚洲区唯一的最佳组合型生物砖（Best New Composite part）的单项奖。
2014年，指导的iGEM本科生实验队SYSU-China获全国大学生“小平科技创新团队”称号。
2015年，指导本科生实验队SYSU-China获得国际基因工程机器设计大赛（iGEM）全球决赛金牌。
2016年，指导本科生实验队SYSU-China获得国际基因工程机器设计大赛（iGEM）全球决赛金牌。
2018年，指导本科生实验队SYSU-China获得国际基因工程机器设计大赛（iGEM）全球决赛金牌。
2018年，第八届广东省教育教学成果奖 “遗传学课程教学立体化建设的探索与实践”，二等奖（排名第二）。

学术成就
中山大学双一流建设“细胞基因编辑研究和应用”方向的团队负责人；生命科学学院基因编辑动物平台负责人。在Nature、Nature Communications、Molecular Cell、Cell Research、Stem Cells、Protein Cell等国际专业杂志上发表论文超65篇，影响因子超450点，总引用超2500次。授权专利2项，申请专利14项。世界上首次在人类胚胎通过CRISPR/Cas9技术和单碱基编辑技术修正地中海贫血症的突变基因，被Nature、Science等科技媒体的热点报道，工作入选 2015年Science杂志年度十大突破介绍和2017年Nature杂志全球年度科学事件盘点。2019年率先建立了系统评估单碱基编辑系统靶向效率的EndoV-Seq技术，被Science等杂志引用；建立了国际上首个基因编辑地中海贫血食蟹猴模型，其表型与人类疾病相似。2020年，建立双AAV介导单碱基编辑器体内编辑靶细胞基因的递送系统。2014年入选广东特支计划百千万青年拔尖人才；2015年，Nature杂志评选黄军就为年度全球十大科学人物；2015年，中国与全球化智库(CCG)评为“2015年中国留学人员创新创业50人”；2016年，获得中国干细胞协会评“干细胞青年研究员奖”；2017年，中国遗传学会基因编辑分会第一届学术委员会委员；2018年，广东省地中海贫血专委会副主任委员；2018年获邀为中国工程院全球工程前沿战略咨询研究项目医药卫生领域专家。2019年，中国遗传学会基因编辑分会第二届学术委会委员;中国医药生物技术协会基因编辑技术分会常委委员; 中国优生科学协会儿科临床与保健分会遗传与基因治疗学组委员。2020年，国家自然科学基金委生命科学部学科评审组专家。科研工作获得国家重点研发计划（组长和骨干各1项），国家基金委面上项目（3项）和青年基金，广东省自然科学基金、广州市科技攻关项目等资助。

承担课题
1.单碱基编辑治疗RHO点突变视网膜色素变性的小鼠模型研究，国家自然科学基金面上基金，60万，2020.01-2023.12，主持
2.儿童重症遗传病的基因编辑、干细胞及药物治疗，国家重点研发计划，406万，2017.07-2020.12 ，组长
3.多能干细胞自我更新和分化的表观遗传调控研究，国家重点研发计划，376.5万，2017.07-2021.12，骨干
4. CRISPR/Cas9技术治疗单纯疱疹病毒疾病的研究，广东省自然科学基金面上项目，10万，2017.05-2020.05，主持
5.细胞基因编辑技术研究，中山大学-细胞生物学研究平台，300万，2016.01-2016.12，主持
6.Bend5调控胚胎干细胞分化为原始生殖细胞的分子机制研究，国家自然科学基金面上基金，65万，2017.01-2020.12，主持
7.广东特支计划百千万青年拔尖人才，10万，2016.01-2016.12，主持
8. Nanog特异结合lncRNAs调控胚胎干细胞分化的机制研究，广东省公益研究与能力建设专项，30万，2015.09-2017.08，主持
9.HMBOX1在干细胞端粒功能和多能性调控中的作用和机制研究，国家自然科学基金面上基金，80万，2014.01-2017.12，主持
10.人端粒体相关调控蛋白的筛选、鉴定和功能研究，国家自然科学基金青年基金，28万，2011.01-2013.12，主持
11. Oct4相关蛋白对胚胎干细胞多能性调控机制的研究，2011年首届珠江科技新星专项，30万，2011.11-2014.10，主持
12. 人RCC1与Rap1在细胞凋亡中相互作用机制研究，博士后基金-面上，3万，2010.12-2012.12，主持
13. 胚胎干细胞LIF通路中Oct4相关调节蛋白的筛选和功能研究，博士后基金-第四批特别资助，10万，2011.09-2012.12，主持

论文专著
通讯作者*文章：
1.Wang J, Huang J*, Shi G*. Retrotransposons in pluripotent stem cells. Cell Regen. 2020 Jun 2;9(1):4.
2.Shi G#, Hu Y#, Zhu X, Jiang Y, Pang J, Wang C, Huang W, Zhao Y, Ma W, Liu D, Huang J*, Songyang Z*. A critical role of telomere chromatin compaction in ALT tumor cell growth. ?Nucleic Acids Res. 2020 Jun 19;48(11):6019-6031.
3.Chen Y#, Zhi S#, Liang P, Zheng Q, Liu M, Zhao Q, Ren J, Cui J, Huang J*, Liu Y*, Songyang Z*. Single AAV-Mediated CRISPR-SaCas9 Inhibits HSV-1 Replication by Editing ICP4 in Trigeminal Ganglion Neurons. Mol Ther Methods Clin Dev. 2020 May 22;18:33-43.
4.Chen Y#, Zhi S#, ?Liu W#,Wen J#,Hu S, Cao T, Sun H, Li Y, Huang L, Liu Y, Liang P*, Huang J* Development of Highly Efficient Dual-AAV Split Adenosine Base Editor for In Vivo Gene Therapy. Small Methods 2020
5.Sun H#, Zhi S#, Wu G, Wu G, Cao T, Hao H, Songyang Z*, Liang P*, Huang J*. Cost-effective generation of A-to-G mutant mice by zygote electroporation of adenine base editor ribonucleoproteins. Journal of Genetics and Genomics. 2020
6. Deng Q#, Huang S#, Wen J, Jiao Y, Su X, Shi G*, Huang J*. PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton’s jelly mesenchymal stem cells-mediated skin wound healing in mice. Stem Cell Research & Therapy. 2020 Apr 3;11(1):143.
7.Su X#, Chen W#, Cai Q, Liang P, Chen Y, Cong P*, Huang J*.Effective generation of maternal genome point mutated porcine embryos by injection of cytosine base editor into germinal vesicle oocytes. Sci China Life Sci. 2020 Jan 21
8. Liang P, Wen J, Huang J*. Off-target effects of cytidine base editor and adenine base editor: What can we do? J Genet Genomics. 2019 Nov 20;46(11):509-512 邀请评述
9.Su X#, Chen W#, Cai Q, Liang P, Chen Y, Cong P*, Huang J*. Production of non-mosaic genome edited porcine embryos by injection of CRISPR/Cas9 into germinal vesicle oocytes.J Genet Genomics. 2019 Jul 20. 封面文章
10. Lu W*, Yu J, Shi F, Zhang J, Huang R, Yin S, Songyang Z*, Huang J*. The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency. Stem Cell Research & Therapy. 2019
11. Huang Y#, Ding C#, Liang P#, Li D, Tang Y, Meng W, Sun H, Lu H, Chen Y, Chen X, Huang Q, Fang J, Zhou C*, Yang S*, Huang J*. HBB-deficient Macaca fascicularis monkey presents with human β-thalassemia. Protein Cell. 2019 May 20. 首次构建猴子地中海贫血症模型
12. Lin Z, Liang P, Yao Z, Chen Y, Zhang X, Huang R, Zhang Z, Li M, Ma W, Zheng H, Cao S, Shi G, Zhao X, Songyang Z*, Huang J*. A novel undifferentiated spermatogonia-specific surface protein 1 (USSP1) in neonatal mice. Science Bulletin. 2019.
13. Liang P, Huang J*. Off-target challenge for base editor-mediated genome editing. Cell Biol Toxicol. 2019 Apr 30. 王向东教授主编，邀请评论
14. Yu J#, Lu W#, Ge T, Huang R, Chen B, Ye M, Bai Y, Shi G, Songyang Z, Ma W*, Huang J*. Interaction between Sympk and Oct4 Promotes Mouse Embryonic Stem Cell Proliferation. Stem Cells. 2019 Feb 23.
15. Liang P#, Xie X#, Zhi S, Sun H, Zhang X, Chen Y, Chen Y, Xiong Y, Ma W, Liu D, Huang J*, Songyang Z*. Genome-wide profiling of adenine base editor specificity by EndoV-seq. Nature Communications. 2019 Jan 8;10(1):67. 首次建立单碱基编辑器ABE在全基因组靶向特异的评价系统
16. Liang P#, Sun H#, Zhang X, Xie X, Zhang J, Bai Y, Ouyang X, Zhi S, Xiong Y, Ma W, Liu D, Huang J*, Songyang Z*. Effective and precise adenine base editing in mouse zygotes. Protein Cell. 2018 Jul 31. 杂志Highlight重点推荐
17. Zhang Z, Wan T, Chen Y, Chen Y, Sun H, Cao T, Songyang Z, Tang G, Wu C, Ping Y*, Xu FJ*, Huang J*. Cationic Polymer-Mediated CRISPR/Cas9 Plasmid Delivery for Genome Editing. Macromol Rapid Commun. 2018 Apr
18. Zhan S, Cao S, Du H, Sun Y, Li L, Ding C, Zheng H*, Huang J*. Parental genetic material and oxygen concentration affect hatch dynamics of mouse embryo in vitro. Reprod Biol Endocrinol. 2018 Apr 21;16(1):39.
19. 孙宏伟，梁普平，黄军就*．《人类胚胎单碱基编辑治疗遗传疾病的研究》生命科学. 2018.8， https://doi.org/10.13376/j.cbls/**
20. Testis-specific Lypd9 is dispensable for spermatogenesis in mouse. Feng J, Liang P, Chen Y, Zhang X, Songyang Z, Zheng H, Cao S, Huang J*. Molecular Reproduction and Development. 10-Dec-2017 IF:2.12
21. 刘佳慧, 梁普平, 时光, 黄军就*.《单碱基基因编辑系统的应用和展望》? 世界科技研究与进展2017-11-10
22. Liang P, Ding C, Sun H, Xie X, Xu Y, Zhang X, Sun Y, Xiong Y, Ma W, Liu Y, Wang Y, Fang J, Liu D, Songyang Z*, Zhou C*, Huang J*. Correction of β-thalassemia mutant by base editor in human embryos.Protein Cell. 2017 Sep 23. ESI高引论文，首次在人胚胎中证实单碱基编辑技术有望阻断点突变遗传疾病，Nature、Science等科技媒体报道，Nature杂志年度盘点2017年全球科学重要事件中介绍本工作。
23. Chen Y, Liang P, Huang Y, Li M, Zhang X, Ding C, Feng J, Zhang Z, Zhang X, Gao Y, Zhang Q, Cao S, Zheng H, Liu D, Songyang Z*, Huang J*. Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility. Cell Discovery (2017) 3, 17030
24. Liang P, Zhang X, Chen Y, Huang J*. Developmental history and application of CRISPR in human disease. J Gene Med. 2017 杂志highlights
25. Liang P, Sun H, Sun Y, Zhang X, Xie X, Zhang J, Zhang Z, Chen Y, Ding C, Xiong Y, Ma W, Liu D, Huang J*, Songyang Z* Effective gene editing by high-fidelity base editor 2 in mouse zygotes. Protein Cell 2017 杂志Highlight重点推荐
26. Huang D, Lu W, Zou S, Wang H, Jiang Y, Zhang X, Li P, Songyang Z, Wang L, Wang J, Huang J*, Fang L*. Rho GDP-dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer. Cancer Sci. 2017 Apr 17.
27. Jiang S, Tang M, Xin H, Huang J*. Assessing Telomerase Activities in Mammalian Cells Using the Quantitative PCR-Based Telomeric Repeat Amplification Protocol (qTRAP). Methods Mol Biol. 2017;1587:95-101.
28. Lin Z, Bao J, Kong Q, Bai Y, Luo F, Songyang Z, Wu Y*, Huang J*. Effective production of recipient male pigs for spermatogonial stem cell transplantation by intratesticular injection with busulfan. Theriogenology. 2017 Feb;89:365-373
29. Chen M, Meng Q, Qin Y, Liang P, Tan P, He L, Zhou Y, Chen Y, Huang J*, Wang RF*, Cui J*. TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses. Mol Cell. 2016 Oct 6;64(1):105-119.
30. Zhang X, Liang P, Ding C, Zhang Z, Zhou J, Xie X, Huang R, Sun Y, Sun H, Zhang J, Xu Y, Songyang Z, Huang J*. Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9. Sci Rep. 2016 Sep 2;6:32565.
31. Hu Y, Shi G*, Zhang L, Li F, Jiang Y, Jiang S, Ma W, Zhao Y, Songyang Z, Huang J*. Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX. Sci Rep. 2016 Aug 31;6:32280.
32. 梁普平，黄军就*, 推开人类胚胎基因研究的神秘大门。《生命科学》 2016 年4月，第28卷 第4期。王恩多院士特约综述，周琪院士点评。
33. Huang Y, #, Xiong Y, #, Lin Z, Feng X, Jiang X, Songyang Z, Huang J* Specific Tandem 3'UTR Patterns and Gene Expression Profiles in Mouse Thy1+ Germline Stem Cells. Plos ONE 2015
34. Li, M., Huang, R., Jiang, X., Chen, Y., Zhang, Z., Zhang, X., Liang, P., Zhan, S., Cao, S., Songyang, Z.*, Huang J* CRISPR/Cas9 Promotes Functional Study of Testis Specific X-linked Gene in vivo. PLOS ONE 2015
35. Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., Lv, J., Xie, X., Chen, Y., Li, Y., Sun, Y., Bai, Y., Songyang, Z., Ma, W., Zhou, C*., Huang, J*. (2015). CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes. Protein & cell 6, 363-372. ESI高引论文, Nature、Science等媒体热点报道。2 015年，Nature杂志评选为全球年度十大科学人物 。
36. Lu, W., Fang, L., Ouyang, B., Zhang, X., Zhan, S., Feng, X., Bai, Y., Han, X., Kim, H., He, Q., Wan, M., Shi, F., Feng, X., Liu, D., Huang, J*., Songyang, Z*. (2015). Actl6a protects embryonic stem cells from differentiating into primitive endoderm. Stem cells 33, 1782-1793.
37. Luo, Z., Feng, X., Wang, H., Xu, W., Zhao, Y., Ma, W., Jiang, S., Liu, D., Huang, J*., and Songyang, Z*. (2015). Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression. Aging cell 14, 391-399.
38. Zhan, S., Zhang, X., Cao, S., and Huang, J*. (2015). Benzo(a)pyrene disrupts mouse preimplantation embryo development. Fertility and Sterility 103, 815-825.
39. Huang, Y., Liang, P., Liu, D., Huang, J*., and Songyang, Z*. (2014). Telomere regulation in pluripotent stem cells. Protein & cell 5, 194-202.
40. Zhang, S., Luo, Z., Shi, G., Liu, D., Songyang, Z*., Huang, J*. TPP1 as a versatile player at the ends of chromosomes. Front. Biol., 2014, 9(3): 225-233.
41. Feng X, Luo Z, Jiang S, Li F, Han X, Hu Y, Wang D, Zhao Y, Ma W, Liu D, Huang J*, Songyang Z*. The telomere-associated home
obox-containing protein TAH1 participates in telomere maintenance in ALT Cells. J Cell Sci 2013.
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第一作者文章：
1. Huang J, Okuka M, Lu W, Tsibris JC, McLean MP, Keefe DL, Liu L. Telomere shortening and DNA damage of embryonic stem cells induced by cigarette smoke. Reprod Toxicol; 35: 89-95, 2012. IF: 3.7
2. Huang J, Wang F, Okuka M, Liu N, Ji G, Ye X, Zuo B, Li M, Liang P, Ge WW, Tsibris JC, Keefe DL, Liu L. Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res; 21: 779-792, 2011. IF: 14.0
3. Huang J, Okuka M, McLean M, Keefe DL, Liu L. Telomere susceptibility to cigarette smoke-induced oxidative damage and chromosomal instability of mouse embryos in vitro. Free Radic Biol Med; 48: 1663-1676, 2010. IF: 5.8
4. Huang J, Okuka M, Wang F, Zuo B, Liang P, Kalmbach K, Liu L, Keefe DL. Generation of pluripotent stem cells from eggs of aging mice. Aging Cell; 9: 113-125, 2010.封面文章IF: 5.7
5. Huang J, Okuka M, McLean M, Keefe DL, Liu L. Effects of cigarette smoke on fertilization and embryo development in vivo. Fertil Steril; 92: 1456-1465, 2009.封面文章IF: 4.2
6. Huang J, Deng K, Wu H, Liu Z, Chen Z, Cao S, Zhou L, Ye X, Keefe DL, Liu L.* Efficient production of mice from embryonic stem cells injected into four- or eight-cell embryos by piezo micromanipulation. Stem Cells; 26: 1883-1890, 2008. IF: 5.9
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部分重要合作文章：
Li T, Luo Z, Lin S, Li C, Dai S, Wang H, Huang J, Ma W, Songyang Z, Huang Y. MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. Aging (Albany NY). 2020 Jul 18;12(14):14791-14807.
Chen Y, Liu J, Zhi S, Zheng Q, Ma W, Huang J, Liu Y, Liu D, Liang P, Songyang Z. Repurposing type I-F CRISPR-Cas system as a transcriptional activation tool in human cells. Nat Commun. 2020 Jun 19;11(1):3136.
Wang J, Liu J, Ye M, Liu F, Wu S, Huang J, Shi G. Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex. Stem Cell Res Ther. 2020 Jul 23;11(1):314.
Chen M, Zhao Z, Meng Q, Liang P, Su Z, Wu Y, Huang J, Cui J. TRIM14 Promotes Noncanonical NF-κB Activation by Modulating p100/p52 Stability via Selective Autophagy. Adv Sci (Weinh). 2019 Nov 11;7(1):**
Ge Y, Wu S, Zhang Z, Li X, Li F, Yan S, Liu H, Huang J, Zhao Y. Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers. Protein Cell. 2019 May 21.
Deng T, Huang Y, Weng K, Lin S, Li Y, Shi G, Chen Y, Huang J, Liu D, Ma W, Songyang Z. TOE1 acts as a 3' exonuclease for telomerase RNA and regulates telomere maintenance. Nucleic Acids Res. 2019 Jan 10;47(1):391-405.
Xie Y, Luo X, Li Y, Chen L, Ma W, Huang J, Cui J, Zhao Y, Xue Y, Zuo Z, Ren J. DeepNitro: Prediction of Protein Nitration and Nitrosylation Sites by Deep Learning. ?Genomics Proteomics Bioinformatics. 2018 Aug;16(4):294-306.
Jin S, Zhang X, Miao Y, Liang P, Zhu K, She Y, Wu Y, Liu DA, Huang J, Ren J, Cui J. m6A RNA modification controls autophagy through upregulating ULK1 protein abundance. Cell Res. 2018 Jul 25. doi: 10.1038/s41422-018-0069-8.
Wang M, Zhang S, Zheng G, Huang J, Songyang Z, Zhao X, Lin X. Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A. Immunity. 2018 Jul 17;49(1):66-79.e5. doi: 10.1016/j.immuni.2018.05.012 IF:21.52
Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats.? Yang H, Wu S, Feng R, Huang J, Liu L, Liu F, Chen Y. Stem Cell Res Ther. 2017 Nov 21;8(1):267. IF:4.2
?Zhang T, Zhang Z, Li F, Hu Q, Liu H, Tang M, Ma W, Huang J, Songyang Z, Rong Y, Zhang S, Chen BP, Zhao Y. Looping-out mechanism for resolution of replicative stress at telomeres. EMBO Rep. 2017 IF:8.6
Zheng XH, Nie X, Fang Y, Zhang Z, Xiao Y, Mao Z, Liu H, Ren J, Wang F, Xia L, Huang J, Zhao Y. A Cisplatin Derivative Tetra-Pt(bpy) as an Oncotherapeutic Agent for Targeting ALT Cancer. J Natl Cancer Inst. 2017 Oct 1;109(10). IF:14
Liang W, Liang P, Wong C, Ng T, Huang J, Zhang J, Waye M, Fu W. CRISPR/Cas9 Technology Targeting Fas Gene Protects Mice From Concanavalin-A Induced Fulminant Hepatic Failure. J Cell Biochem. 2017 Mar;118(3):530-536 IF:3.1
Burgess S, Cheng L, Gu F, Huang J, Huang Z, Lin S, Li J, Li W, Qin W, Sun Y, Songyang Z, Wei W, Wu Q, Wang H, Wang X, Xiong JW, Xi J, Yang H, Zhou B, Zhang B. Questions about NgAgo. Protein Cell. 2016 Nov 15. IF:3.8
Ge Y, Wu S, Xue Y, Tao J, Li F, Chen Y, Liu H, Ma W, Huang J, Zhao Y*. Preferential extension of short telomeres induced by low extracellular pH. Nucleic Acids Res. 2016 Sep 30;44(17):8086-96. IF:9.0
Huang Y, Chen B, Ye M, Liang P, Zhangfang Y, Huang J, Liu M, Songyang Z, Ma W*. Ccndbp1 is a new positive regulator of skeletal myogenesis. J Cell Sci. 2016 Jul 15;129(14):2767-77. IF:6.4
Zhang Y, Wu Y, Mao P, Li F, Han X, Zhang Y, Jiang S, Chen Y, Huang J, Liu D, Zhao Y, Ma W*, Songyang Z*. Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner. Nucleic Acids Res. 2015 IF:9.0
He Q, Kim H, Huang R, Lu W, Tang M, Shi F, Yang D, Zhang X, Huang J, Liu D, Songyang Z*. (2015). The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation. Cell Stem Cell. 3;17(3):273-86 IF:22.3
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