王莫，博士，教授，博士生导师，硕士生导师
在国际主流学术杂志发表论文18篇，其中第一作者7篇。曾获得中国科学院院长优秀奖、朱李月华优秀博士生奖、振声奖学金优秀奖、北京生命科学研究院优秀研究生奖、保罗生物科技优秀学生特别奖、中国科学院优秀博士学位论文，中国科学院优秀毕业生奖等多个奖项。目前作为PLOS ONE的审稿人。


联系方式：
邮箱：wangmo108@163.com


学习及工作经历：
2017.3- 福建农林大学植物免疫研究中心，教授
2013.3-2017.1俄亥俄州立大学，博士后
2006.9-2013.3 中国科学院遗传与发育生物学研究所，遗传学，博士
2002.9 -2006.7 中国农业大学，农学，学士


研究方向：
植物免疫反应主要分为两个层次：第一道防线是来自于细胞表面的模式识别受体(pattern-recognition receptors, PRRs) 对病原菌(pathogen-associated molecular patterns, PAMPs) 的识别。由PAMP介导的免疫反应称作PTI (PAMP-triggered immunity)，其赋予植物对病原菌的广谱抗性。而经过长期自然筛选，病原菌通过分泌effector蛋白可以抑制宿主的PTI，随之植物也进化出由R基因介导防御的第二道防线(effector-triggered immunity，ETI)，即植物R蛋白直接或间接识别effector蛋白，从而产生细胞坏死以抑制病原菌的生长。我们实验室主要以拟南芥和水稻为研究材料，通过遗传学、细胞生物学、生物化学等研究方法，克隆植物PTI及ETI通路的抗病基因并对其功能进行深入研究。此外，我们还在探索细菌及真菌性病原菌所产生的毒性蛋白影响植物生长发育的分子机理。
具体研究内容包括以下几方面：
1. 植物叶绿体蛋白参与免疫反应的分子机制
2. 染色体重组蛋白以及细胞周期调节因子调控植物防御反应的机理研究
3. 植物细菌性病原菌分泌的Harpin 蛋白激活植物免疫反应的分子机理
4. 稻曲病的发病机理以及水稻抗稻曲病基因的克隆与功能分析
发表文章：
以第一作者发表的文章：
1.Wang M, Zhang K, Yan HJ, Zhao WY, Lin JE, Shi H, Rui L, Blakeslee JJ, Mackey D, Tang DZ, Wei ZM and Wang GL (2016). The major leaf ferredoxin Fd2 regulates plant innate immunity in Arabidopsis.(in submission).
2.Wang M, Tang D, Luo Q, Jin Y, Shen Y, Wang KJ and Cheng ZK (2012). BRK1, the Bub1-related kinase, is essential for generating proper tension between homologous kinetochores at metaphase I in rice meiosis. Plant Cell24: 4961-4973.
3.Wang M, Tang D, Wang KJ, Shen Y, Qin BX, Miao CB, Li M and Cheng ZK (2011). OsSGO1 maintains synaptonemal complex stabilization in addition to protecting centromericcohesion during rice meiosis. Plant Journal67: 583-594.
4.Wang M, Wang KJ, Tang D, Wei CX, Li M, Shen Y, Chi ZC, Gu MH and Cheng ZK(2010). The Central Element Protein ZEP1 of the Synaptonemal Complex Regulates the Number of Crossovers during Meiosis in Rice. Plant Cell22: 417-430.
5.Wang KJ^*, Wang M^*, Tang D^*, Miao CB, Hu Q, Lu TG and Cheng ZK (2012). The Role of Rice HEI10 inthe Formation of Meiotic Crossovers. PLoS Genetics 8: e**.(* Co-first authors)
6.Wang KJ^*, Wang M^*, Tang D^*, Shen Y, Qin BX, Li M and Cheng ZK (2011). PAIR3, an axis-associated protein, is essential for the recruitment of recombination elements onto meiotic chromosomes in rice. Molecular Biology of the Cell22:12-19 (* Co-first authors).
7.Yu HX^*, Wang M^*, Tang D, Wang KJ, Chen FL., Gong ZY, Gu MH and Cheng ZK (2010). OsSPO11 is essential for both homologous chromosome pairing and crossover formation in rice. Chromosoma119: 625-636(* Co-first authors).
8.Zhang BW^*, Wang M^*, Tang D, Li YF, Xu M, Gu MH, Cheng ZK, Yu HX(2015).XRCC3 is essential for proper double-strand break repair and homologous recombination in ricemeiosis. Journal of Experimental Botany66:5713-5725 (* Co-first authors).

以共同作者发表的文章：
1.Park CH, Shirsekar G, Bellizzi M, Chen SB, Songkumarn P, Xie X, Shi XT, Ning Y, Zhou B, Suttiviriya P, Wang M, Umemura KJ, Wang GL (2016). The E3 Ligase APIP10 Connects the Effector AvrPiz-t to the NLR Receptor Piz-t in Rice. PLoS Pathogens12: e**.
2.Liu JL, Park CH, He F, Nagano M, Wang M, Bellizzi M, Zhang K, Zeng XS, Liu WD, Ning Y, Kawano YJ, Wang GL (2015). The RhoGAP SPIN6 Associates with SPL11 and OsRac1 and Negatively Regulates Programmed Cell Death and Innate Immunity in Rice. PLoS Pathogens11: e**.
3.WangN, WangM, ZhuYH, GroselTW, SunDK, KudryashovDS, WuJQ (2015). The Rho-GEF Gef3 interacts with the septin complex and activates the GTPase Rho4 during fission yeast cytokinesis. Molecular Biology of the Cell26: 238-255.
4.Miao CB, Tang D, Zhang HG, Wang M, Li YF, Tang SZ, Yu HX, Gu MH, Cheng ZK (2013). CENTRAL REGION COMPONENT1, a Novel Synaptonemal Complex Component, Is Essential for Meiotic Recombination Initiation in Rice. Plant Cell25: 2998-3009.
5.Luo Q, Tang D, Wang M, Luo WX, Zhang L, Qin BX, Shen Y, Wang KJ, Li YF and Cheng ZK (2013). The Role of OsMSH5 in Crossover Formation during Rice Meiosis. Molecular Plant6: 729-742.
6.Shen Y, Tang D, Wang KJ, Wang M, Huang J, Luo WX, Luo Q, Hong LL, Li M and Cheng ZK (2012). ZIP4 inhomologous chromosome synapsis and crossover formation in rice meiosis. Journal of Cell Science125: 2581–2591.
7.Ji JH, Tang D, Wang KJ, Wang M, Che LX, Li M and Cheng ZK (2012). The role of OsCOM1 inhomologous chromosome synapsis and recombination in rice meiosis. Plant Journal72: 18–30.
8.Che LX, Tang D, Wang KJ, Wang M, Zhu KM, Yu HX, Gu MH and Cheng ZK (2011). OsAM1 is required for leptotene-zygotene transition in rice. Cell Research21:654–665.
9.Shao T, Tang D, Wang KJ, Wang M, Che LX, Qin BX, Yu HX, Li M, Gu MH and Cheng ZK (2011). OsREC8 is essential for chromatid cohesion and metaphase I monopolar orientation in rice meiosis I. Plant Physiology156: 1386-1396.
10.Xu J, Sun XJ, Jing YD, Wang M, Liu K, JianYL, Yang M, Cheng ZK and Yang CL (2011). MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells. Cell Research22: 886-902.
11.Wang KJ, Tang D, Wang M, Lu JF, Yu HX, Liu JF, Qin BX, Gong ZY, Wang X, Chen JM, Gu MH and Cheng ZK (2009). MER3 is required for normal meiotic crossover formation, but not for presynaptic alignment in rice. Journal of Cell Science122: 2055-2063.