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一种基于声卡的CAPs检测系统的研制

清华大学 辅仁网/2017-07-07

一种基于声卡的CAPs检测系统的研制
宫琴1,2(),黎婷婷1,刘帅2
2. 清华大学 深圳研究生院, 生物医学研究中心, 深圳 518055
Sound card-based CAPs detection system
Qin GONG1,2(),Tingting LI1,Shuai LIU2
1. Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China
2. Research Center of Biomedical Engineering, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China

摘要:
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摘要听神经复合动作电位(CAPs)的阈值曲线和调谐曲线分别反映了听神经系统对刺激声的强度灵敏度和频率灵敏度。为了全面、客观、方便地提取听神经系统的信息,该文基于多媒体外置声卡、使用C#语言编写对声卡的控制程序设计了CAPs检测系统,实现了对声音刺激下CAPs 电信号的采集,并获取了用于表征听神经系统功能状况的CAP阈值曲线和调谐曲线。该系统为听神经复合动作电位的检测和后续研究提供了综合、客观的分析研究平台,具有较高的使用价值。

关键词 听神经复合动作电位,阈值曲线,调谐曲线
Abstract:Auditory nerve compound action potential (CAPs) threshold curves reflects the sensitivity of sound intensity while tuning curves reflects the frequency in the auditory nerve system. A CAPs detection system was developed based on an external multimedia sound card and the C# language to simplify data extraction for the auditory nerve system and to obtain more comprehensive and objective information. CAPs, threshold curves and tuning curves were acquired using sound stimulation to study the condition of the auditory nerve system. The system provides a comprehensive and objective analysis platform for detection and research of auditory nerve compound action potentials.

Key wordscompound action potentialsthreshold curvestuning curves
收稿日期: 2013-05-01 出版日期: 2015-09-03
ZTFLH: 
基金资助:国家自然科学基金资助项目 (61271133);教育部博导基金资助项目 (20120002110054)
引用本文:
宫琴, 黎婷婷, 刘帅. 一种基于声卡的CAPs检测系统的研制[J]. 清华大学学报(自然科学版), 2014, 54(5): 678-684.
Qin GONG, Tingting LI, Shuai LIU. Sound card-based CAPs detection system. Journal of Tsinghua University(Science and Technology), 2014, 54(5): 678-684.
链接本文:
http://jst.tsinghuajournals.com/CN/ http://jst.tsinghuajournals.com/CN/Y2014/V54/I5/678


图表:
检测系统的组成框图
系统软件框架流程图
测试控制流程图
实验信息录入页面
探头/电极位置校准页面
CAP / CM 、刺激声波形
CAP阈值曲线测试页面
CAP调谐曲线测试页面


参考文献:
[1] Pickles J O. An Introduction to the Physiology of Hearing [M]. 2nd Ed. London, UK: Academic Press Inc, 1988.
[2] Dallos P, Cheatham M A. Compound action potential (AP) tuning curves[J].Journal of the Acoustical of Society of America, 1976, 59(3): 591-597.
[3] Harrison R V, Aran J M, Erre J P. AP tuning curves from normal and pathological human and guinea pig cochleas[J].Journal of the Acoustical of Society of America, 1981, 69(5): 1374-1385.
[4] Eggermont J J. Compound action potential tuning curves in normal and pathological human ears[J].Journal of the Acoustical of Society of America, 1977, 62(5): 1247-1251.
[5] Ruggero M A, Temchin A N. Unexceptional sharpness of frequency tuning in the human cochlea[J].Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(51): 18614-18619.
[6] Salt A N, Garcia P. Cochlear action potential tuning curves recorded with a derived response technique[J]. Journal of the Acoustical of Society of America, 1990, 88(3): 1392-1402.
[7] 甘群文. C#多线程同步与异步的实现[J]. 电脑开发与应用, 2009, 22(9): 35-40. GAN Qunwen. The implementation of C# multi-thread synchronous and asynchronous modes[J]. Computer Development & Applications, 2009, 22(9): 35-40. (in Chinese)
[8] 凌建辉. 浅谈C#线程同步的几种方法[J]. 信息与电脑, 2009(11): 128-128. LING Jianhui. On the C # thread synchronization in several ways[J]. China Computer & Communication, 2009(11): 128-128. (in Chinese)
[9] 詹发荣. 巧用C#.NET 中委托和事件[J]. 宁夏师范学院学报: 自然科学, 2009, 30(6): 64-67. ZHAN Farong. Skillfully using delegates and events of the C#.NET[J]. Journal of Ningxia Teachers University: Natural Science, 2009, 30(6): 64-67. (in Chinese)
[10] 张金凤, 邱天爽. 诱发电位波形提取方法及进展[J]. 北京生物医学工程, 2003, 22(4): 303-307. ZHANG Jinfeng, QIU Tianshuang. Evoked potential waveform extraction method and progress[J]. Beijing Biomedical Engineering, 2003, 22(4): 303-307. (in Chinese)
[11] 杨军, 吴宝明, 彭承琳. 听觉诱发电位信号分析技术进展[J]. 生物医学工程杂志, 2003, 20(3): 563-566. YANG Jun, WU Baoming, PENG Chenglin. Advance in signal analysis of auditory evoked potential[J]. Journal of Biomedical Engineering, 2003, 20(3): 563-566. (in Chinese)
[12] 王德增, 白净, 杨福生. 检测和分离生物组织超声反射波和散射波的方法──相关系数平方包络线峰值阈值法[J]. 清华大学学报:自然科学版, 1993, 33(1): 39-46. WANG Zengde, BAI Jing, YANG Fusheng. Detection and separation of ultrasonic reflected and scattered waves from biological tissues by EPCCSDT method[J]. Journal of Tsinghua University: Science and Technology , 1993, 33(1): 39-46. (in Chinese)
[13] Jones H G, Koka K, Tollin D J. Postnatal development of cochlear microphonic and compound action potentials in a precocious species, Chinchilla lanigera[J]. Journal of the Acoustical of Society of America, 2011, 130(1): 38-43.
[14] 张家騄. 听觉部位学说与频率差阈[J]. 声学学报, 2006, 31(2): 97-100. ZHANG Jialu. On the place theory and the frequency difference limen of hearing[J].Acta Acustica, 2006, 31(2): 97-100. (in Chinese)


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