), 刘珍莉1, 陈钰1, 买晓琴3,4() 1 深圳大学心理与社会学院
2 深圳市情绪与社会认知科学重点实验室, 深圳 518060
3 中国人民大学心理学系
4 中国人民大学心理学系实验室, 北京 100872
收稿日期:2018-08-01出版日期:2019-02-25发布日期:2018-12-24通讯作者:张丹丹,买晓琴E-mail:zhangdd05@gmail.com;maixq@ruc.edu.cn基金资助:中国人民大学中央高校建设世界一流大学(学科)和特色发展引导专项资金支持The role of right ventrolateral prefrontal cortex on social emotional regulation in subclinical depression: An tDCS study
ZHANG Dandan1,2,3,4(), LIU Zhenli1, CHEN Yu1, MAI Xiaoqin3,4() 1 College of Psychology and Sociology, Shenzhen University, Shenzhen 518060, China
2 Shenzhen Key Laboratory of Affective and Social Cognitive Science, Shenzhen University, Shenzhen 518060, China
3 Department of Psychology, Renmin University of China, Beijing 100872, China
4 Laboratory of the Department of Psychology, Renmin University of China, Beijing 100872, China
Received:2018-08-01Online:2019-02-25Published:2018-12-24Contact:ZHANG Dandan,MAI Xiaoqin E-mail:zhangdd05@gmail.com;maixq@ruc.edu.cn摘要/Abstract
摘要： 已有的经颅直流电刺激(transcranial direct current stimulation, tDCS)研究证明, 右腹外侧前额叶(right ventrolateral prefrontal cortex, RVLPFC)是社会情绪调节的重要脑区, 激活RVLPFC可显著降低人们对社会性负性情绪体验的强度。社会功能受损是抑郁症患者或抑郁倾向人群的重要特征之一。该群体对社会排斥的敏感性高, 且对负性社会情绪体验的情绪调节能力降低。在本研究中, 我们采用外显的情绪调节任务, 研究了高、低抑郁水平的两组成年人被试在RVLPFC接受阳性tDCS后其情绪调节能力的改变。结果表明, 虽然采用tDCS激活RVLPFC可帮助被试通过情绪调节(认知重评)减弱负性情绪体验, 但高抑郁水平被试的负性情绪强度下降程度明显小于低抑郁水平被试。另外本文还发现, 与源于个人的负性情绪相比, tDCS效应对源于社会的负性情绪(即社会排斥)更强。本研究是采用电或磁刺激提高抑郁人群社会情绪调节能力的首次尝试。实验结果表明, 高抑郁水平成年人的RVLPFC仅通过单次、短时间(34 min)的tDCS激活, 其情绪调节能力并未得到显著提升。这提示对抑郁倾向群体或抑郁症患者的干预或治疗需要多次施加tDCS。
图/表 3
表1本研究四组被试的人口学特征(M ± SD)
| 变量 | 低抑郁倾向 tDCS阳性 刺激 (n = 25) | 高抑郁倾向 tDCS阳性 刺激 (n = 25) | 低抑郁倾向 tDCS伪刺激 (n = 26) | 高抑郁倾向 tDCS伪刺激 (n = 22) |
|---|---|---|---|---|
| 年龄 | 20.73 ± 2.47 | 21.73 ± 3.65 | 21.55 ± 3.22 | 20.89 ± 2.21 |
| 性别, 男/女 | 13/13 | 13/11 | 13/12 | 12/11 |
| SDS | 0.45 ± 0.04 | 0.57 ± 0.08 | 0.43 ± 0.05 | 0.54 ± 0.09 |
| STAI-T | 41.82 ± 6.67 | 41.81 ± 4.62 | 40.88 ± 6.09 | 42.23 ± 3.65 |
表1本研究四组被试的人口学特征(M ± SD)
| 变量 | 低抑郁倾向 tDCS阳性 刺激 (n = 25) | 高抑郁倾向 tDCS阳性 刺激 (n = 25) | 低抑郁倾向 tDCS伪刺激 (n = 26) | 高抑郁倾向 tDCS伪刺激 (n = 22) |
|---|---|---|---|---|
| 年龄 | 20.73 ± 2.47 | 21.73 ± 3.65 | 21.55 ± 3.22 | 20.89 ± 2.21 |
| 性别, 男/女 | 13/13 | 13/11 | 13/12 | 12/11 |
| SDS | 0.45 ± 0.04 | 0.57 ± 0.08 | 0.43 ± 0.05 | 0.54 ± 0.09 |
| STAI-T | 41.82 ± 6.67 | 41.81 ± 4.62 | 40.88 ± 6.09 | 42.23 ± 3.65 |
图1实验流程示意图。A, 实验材料示例。B, 单个试次中刺激的呈现(以个体负性图片为例)。
图1实验流程示意图。A, 实验材料示例。B, 单个试次中刺激的呈现(以个体负性图片为例)。
图2负性情绪强度评定结果。A, 任务、组别和tDCS类型的三重交互作用。B, 任务、图片类型和tDCS类型的三重交互作用。图中的误差条(error bar)表示标准误。*p < 0.05, **p < 0.01, ***p < 0.001。
图2负性情绪强度评定结果。A, 任务、组别和tDCS类型的三重交互作用。B, 任务、图片类型和tDCS类型的三重交互作用。图中的误差条(error bar)表示标准误。*p < 0.05, **p < 0.01, ***p < 0.001。参考文献 49
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