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EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of R

本站小编 Free考研考试/2022-01-02

Jing Tang1,2,4,11,,
Bowei Zhou4,
Melanie J. Scott2,
Linsong Chen2,5,
Dengming Lai2,6,
Erica K. Fan7,
Yuehua Li2,
Qiang Wu8,
Timothy R. Billiar2,10,
Mark A. Wilson2,3,
Ping Wang9,
Jie Fan2,3,10,
1 The Department of Anesthesiology, Affiliated hospital of Guangdong Medical University, Zhanjiang 524000, China;
2 Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA;
3 Research and Development, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA;
4 Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;
5 Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China;
6 Department of Cardiovascular Surgery, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310052, China;
7 University of Pittsburgh The Graduate School of Public Health, Pittsburgh, PA 15213, USA;
8 Laboratory of Tropical Biomedicine and Biotechnology, School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou 571199, China;
9 The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA;
10 McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA;
11 Key Laboratory of Organ Injury/Protection and Translational Medicine of Zhanjiang, Zhanjiang 524000, China
Funds: This work was supported by the National Institutes of Health Grant R01-HL-079669 (J.F. and M.A.W.), National Institutes of Health Grant R01-HL-139547 (J.F. and M.A.W.), National Institutes of Health Grant R01HL076179 (P.W. and J.F.), VA Merit Award 1I01BX002729 (J.F.), VA BLR&D Research Career Scientist Award BX004211 (J.F.), National Natural Science Foundation of China 81671957 (J.T.), Key projects of Guangdong Natural Science Foundation 2018B030311038 (J.T.), Science and Technology Planning Project of Guangdong Province 2016A020215212 (J.T.), and National Institutes of Health Grant R01GM102146 (M.J.S).

Publish Date:2020-02-10




Abstract



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