姓名：田琳 性别：女 职称：教授 招生院所：公共卫生学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：劳动卫生与环境卫生学(博) 劳动卫生与环境卫生学(硕) 研究方向名称：职业性肺部疾病 电子信箱：tianlin@ccmu.edu.cn


社会任职
1. 中国毒理学会工业毒理学专业委员会常务委员
2. 国家环保总局环境与健康专家
3. 卫生部环境与健康专家
4. 北京预防医学会专业委员会委员
5. 中国毒理学会呼吸毒理专业委员会委员
6. 中国煤炭尘肺病防治基金会第一届专家委员会委员
7. 国家科技进步奖评审专家
8. 国家医师资格考试试题开发专家委员会委员
9. 国家自然科学基金同行评审专家
10. 北京市科学技术奖励专家
11. 教育部学位中心学位论文评审专家
12. 《中国职业医学》编委
13. 中国环境科学学会环境医学与健康分会委员
14. 《慢性病学杂志》编委
个人简历
1. 197809-198306:山西医学院卫生系 学习
2. 198307-198608:山西医学院卫生系 助教
3. 198608-198906:山西医学院卫生系 硕士研究生
4. 198907-200007:山西医科大学公共卫生学院 讲师、副教授
5. 200008-200406:复旦大学公共卫生学院 博士研究生
6. 200109-200705:山西医科大学公共卫生学院 教授、副主任
7. 200705-:首都医科大学公共卫生学院 教授、系主任、博士生导师
重要学术论文
1. Qiuyue Li#, Jingping Sun, Xiaowei Chen, Siling Li, Yan Wang, Chunjie Xu, Jing Zhao, Zhonghui Zhu*, Lin Tian*.Integrative characterization of fine particulate matter-induced chronic obstructive pulmonary disease in mice. Sci of Total Environ. 2020,706:135687.SCI
2. Jingping Sun, Qiuyue Li, Ximeng Lian, Zhonghui Zhu, Xiaowei Chen, Wanying Pei, Siling Li, Ali Abbas, Yan Wang*, Lin Tian*.MicroRNA-29b Mediates Lung Mesenchymal-Epithelial Transition and Prevents Lung Fibrosis in the Silicosis Model. Mol Ther-Nucl Acids. 2019,14:20-31 .SCI
3. Zhonghui Zhu1, Xiaowei Chen1, Jingping Sun, Qiuyue Li, Ximeng Lian, Siling Li, Yan Wang, Lin Tian*.Inhibition of nuclear thioredoxin aggregation attenuates PM2.5-induced. Free Radical Bio Med. 2019,130:206-214 .SCI
4. 唐星瑶，田琳*.间充质干细胞在矽肺治疗的研究进展. 山西医科大学学报. 2018,49（10）:1251-1254.核心期刊
5. Yanhua Yu, Yanming Lin, Gengxia Yang, Lin Tian*.The interplay between TGF-β/SMAD and BMP/SMAD signaling pathways in the epithelial mesenchymal transition of A549 cells induced by silica. Toxicol Mech Method. 2018,28(4）:286-292.SCI
6. Xiaoli Li, Guoliang An, Yan Wang, Di Liang, Zhonghui Zhu, Lin Tian*.Targeted migration of bone marrow mesenchymal stem cells inhibits silica-induced pulmonary fibrosis in rats. Stem Cell Res Ther. 2018,10;9:335-347.SCI
7. 李小丽，王炎，朱钟慧，田琳*.间充质干细胞的旁分泌作用在组织损伤修复中的研究进展.. 实用医学杂志. 2018,34（22）:3663-3666.核心期刊
8. Li X(#), Wang Y(#), An G, Liang D, Zhu Z, Lian X, Niu P, Guo C, Tian L*.Bone marrow mesenchymastem cells attenuate silica-induced pulmonary fibrosis via paracrine mechanisms. Toxicol Lett. 2017,270:96-107.SCI
9. Li X(#), An G(#), Wang Y, Liang D, Zhu Z, Lian X, Niu P, Guo C, Tian L*.Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis. Exp Mol Pathol. 2017,102(1):70-77.SCI
10. 宋冬梅，陈丽，马俊香，张媛媛，张诗玄，郭彩霞，陈田，田琳*，牛丕业*.锰对SH—SY5Y细胞线粒体超微结构及功能改变的研究. 实用医学杂志. 2017,33(5):680-683.核心期刊
11. 安国亮，李小丽，王炎，连西濛，朱钟慧，郭彩霞，吴惠慧，田琳*.Micro CT对骨髓间充质干细胞拮抗矽肺大鼠肺纤维化的效果评价. 首都医科大学学报. 2017,38（2}:238-243.核心期刊
12. Ximeng Lian(#), Xiaowei Chen, Jingping Sun, Guoliang An, Xiaoli Li,Yan Wang, Piye Niu, Zhonghui Zhu* and Lin Tian*.MicroRNA-29b inhibits supernatants from silica-treated macrophages from inducing extracellular matrix synthesis in lung fibroblasts. Toxicol Res. 2017,6(6): 878-888.SCI
13. Wang Y(#)，Li X(#)，An G，Zhu Z，Liang D，Lian X，Niu P，Chen L，Tian L*.SB203580 inhibits epithelial-mesenchymal transition and pulmonary fibrosis in a rat silicosis model. Toxicol Lett . 2016,30（259）:28-34.SCI
14. Yan Wang, Di Liang, Zhonghui Zhu, Xiaoli Li, Guoliang An, Piye Niu, Li Chen and Lin Tian*.Bone morphogenetic protein-7 prevented epithelial-mesenchymal transition in RLE-6TN cells. Toxicol Res. 2016,5(3):931-937.SCI
15. Di Liang(#), Guoliang An(#), Zhonghui Zhu, Yan Wang, Gengxia Yang, Xiaoli Li, Piye Niu, Li Chen, Lin Tian*.The protective effects of bone morphogenetic protein-7 against epithelial injury and matrix metalloproteases upregulation induced by silica in vitro. Hum Exp Toxicol. 2016,36 (9) :892-900.SCI
16. G Yang, Z Zhu, Y Wang, A Gao, P Niu, L Chen, L Tian*.Bone morphogenetic protein 7 attenuates epithelial–mesenchymal transition induced by silica. Hum Exp Toxicol. 2016,35(1):69-77.SCI
17. Liang D, Wang Y, Zhu Z, Yang G, An G, Li X, Niu P, Chen L, Tian L*.BMP-7 attenuated silica-induced pulmonary fibrosis through modulation of the balance between TGF-β/Smad and BMP-7/Smad signaling pathway. Chem Biol Interact. 2016,5（243）:72-81.SCI
18. Zhonghui Zhu, Yan Wang, Di Liang, Gengxia Yang, Li Chen, Piye Niu and Lin Tian*.Sodium tanshinone IIA sulfonate suppresses pulmonary fibroblast proliferation and activation induced by silica: role of the Nrf2/Trx pathway. Toxicol Res. 2016,5(1) :116-125.SCI
19. Di Liang, Yan Wang, Zhonghui Zhu, Gengxia Yang, Guoliang An, Xiaoli Li, Piye Niu, Li Chen and Lin Tian*.Increased Bone Morphogenetic Protein-7 and Its Related Pathway Provide Anti-fibrotic Effect on Silica-induced Fibrosis in Vitro. Toxicol Res. 2015,31(4):1511 - 1522.SCI
20. Wang Y, Yang G, Zhu Z, Liang D, Niu P, Gao A, Chen L, Tian L*.Effect of bone morphogenic protein-7 on the expression of mesenchymal-epithelial transition markers in silicosis model. Exp Mol Pathol. 2015,98(3):393-402.SCI
21. Yang J, Bai W, Niu P, Tian L*, Gao A*.Aberrant hypomethylated STAT3 was identified as a biomarker of chronic benzene poisoning through integrating DNA methylation and mRNA expression data. Exp Mol Pathol. 2014,96(3):346-353.SCI
22. Gao A, Yang J, Yang GX, Niu PY, Tian L*.Differential gene expression profiling analysis in workers occupationally exposed to benzene. Sci Total Environ. 2014,472:872-879.SCI
23. 郭伟,田琳*, 曹建彪, 朱钟慧, 吴惠慧, 高艾, 牛丕业.石英对人胚肺成纤维细胞TrxR/Trx表达的影响. 实用医学杂志. 2012,28(14):2315-2317.核心期刊
24. 左昕,田琳*,高艾,牛丕业,郭伟,宋珊珊,朱钟慧.5-氮杂-2’-脱氧胞苷对石英恶转细胞DNA依赖蛋白激酶基因去甲基化作用. 中国职业医学. 2011,38(2):1-3.核心期刊
25. 郭伟, 宋珊珊, 田琳*, 高艾, 左昕, 牛丕业, 朱钟慧, 吴惠慧.RNAi构建PARP-1基因低表达的石英诱发人支气管上皮细胞恶性转化细胞模型. 首都医科大学学报. 2011,32(5):645-649.核心期刊
26. Gao A, Zuo X, Song S, Guo W, Tian L*.Epigenetic modification involved in benzene-induced apoptosis through regulating apoptosis-related genes expression.. Cell Biol Int. 2011,35(4):391-396.SCI
27. 路小婷，李秋营，郭慧芬，宋静，沈秀峰，程亮，吕晶，田琳*.山西省某地环境汞污染对女性生殖健康影响. 中国公共卫生. 2010,26(5):600-601.核心期刊
28. Gao A, Song S, Zuo X, Guo W, Niu P, Tian L*.Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells. Toxicol Lett. 2010,193(3):236-241.SCI
29. Ai Gao, Xin Zuo, Qingjie Liu, Xue Lu, Wei Guo, Lin Tian*.Methylation level of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression. Toxicol Lett. 2010,195(2-3):114-118.SCI
30. 路小婷，李秋营，田琳*，郭慧芬.铅接触对工人血清骨钙素水平的影响. 中国工业医学杂志. 2010,37(1):21-23.核心期刊
31. Ai Gao, Xiao-ting Lu, Qiu-ying Li, Lin Tian*.Effect of the Delta-aminolevulinic Acid Dehydratase Gene Polymorphism on Renal and Neurobehavioral Function in Workers Exposed to Lead in China. Sci Total Environ. 2010,408:4052-4055.SCI
32. L. Tian*, HF Guo, A Gao, XT Lu, QY Li.Effects of Mercury Released from Gold Extraction by Amalgamation on Renal Function and Environment in Shanxi, China. B Environ Contam Tox. 2009,83（4）:71-74.SCI
33. 宋珊珊，高艾，牛丕业，左昕，田琳*.石英诱发人支气管上皮细胞恶性转化模型的建立. 中国职业医学. 2009,36（5）:361-363.核心期刊
34. Gao A, Song S, Wang D, Peng W, Tian L*.Effect of Silicon dioxide on Expression of Poly (ADP-Ribose) Polymerase mRNA and Protein. Cell Biol Int. 2009,33 (7):749-754.SCI
35. 田琳*，郭慧芬，罗宏，周继华， 路小婷， 李秋营，王建武.山西某地区汞的环境污染及对居民肾功能影响. 环境与职业医学. 2008,25（5）:417-419.核心期刊
36. Tian Lin, Lu Xiao-ting, Gao Ai, li Qiu-ying, Jin Tai-yi*.Application of Benchmark Dose for Occupational Epidemiology in Lead Exposure. Toxicol Mech Method. 2008,18（4）:363-367.SCI
37. 路小婷, 李秋营, 郭慧芬，田琳*.铅作业工人神经行为的因子分析. 中国工业医学杂志. 2008,21（4）:222-224.核心期刊
38. Tian Lin, Jin Tai-yi*.Benchmark Dose Approach for Renal Dysfunction in Workers Exposed to Lead. Environ Toxicol. 2007,22（3）:229-233.SCI
主编或副主编的著作/译著
1. 《《预防医学》全国高等教育医学数字化规划教材（国家医学电子书包）》,副主编,人民军医出版社,2016
2. 《职业卫生与职业医学》,副主编,中国协和医科大学出版社,201509
3. 《职业卫生与职业医学》,副主编,中国协和医科大学出版社,200709
4. 《预防专业必修课考试辅导教材《职业卫生与职业医学》》,副主编,科学技术文献出版社,200610
重要奖项
1. 非预防医学专业预防医学课程体系建设及教学改革研究 北京市高等教育教学成果奖 二等奖 201305
2. 《职业卫生与职业病学》教材改革 山西省教学成果奖 一等奖 200809
3. 石英对Ⅱ型上皮细胞的直接损伤作用及功能影响的研究 中国人民解放军科技进步奖 三等奖 199806
4. 矽肺治疗措施及疗效评价 卫生部科技进步奖 三等奖 199607
5. 染尘大鼠BALF中磷脂的变化对肺泡巨噬细胞功能影响研究 山西省科技进步奖 三等奖 199404