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中国医学科学院药物研究所导师教师师资介绍简介-吉腾飞

本站小编 Free考研考试/2020-05-10


吉腾飞

吉腾飞 博士,研究员,博士生导师
联系方式:TEL: 、;E-mail: jitf@imm.ac.cn。
教育背景
1996年7月毕业于新疆师范大学化学系,获得学士学位。
1999年7月毕业于中国科学院新疆化学研究所,获得硕士学位。
2003年1月毕业于北京协和医学院药物研究所,获得药物化学专业博士学位。
工作经历
2003年7月-至今于中国医学科学院药物研究所天然药物化学室工作,先后任助理研究员,副研究员和研究员。2012年9月-2013年9月作为卫生部选派的第七批援疆干部于新疆维吾尔自治区药物研究所植化室工作,任副主任。
专业研究方向领域
1. 基于活性天然产物的新药研究与开发。
2. 新疆特色民族药的药效物质基础研究。
承担的课题
作为项目负责人主持国家自然科学基金、中央科研公益基金重点与团队课题、新疆维吾尔自治区科技支撑计划项目和综合性新药研究开发技术大平台创新药物品种专项等课题10项。作为课题骨干人员参与国家自然基金项目、国家自然基金面上项目、“重大新药创制”科技重大专项3项:国家创新药物研究开发综合性大平台、中药新药发现与评价技术平台和中药标准物质研制和开发的技术平台建设。目前已发表论文60余篇,其中SCI收录30余篇,申请专利5项(一项为援疆期间工作)。
曾获得宁夏回族自治区科学技术进步奖二等奖一项;江西省科学技术进步奖三等奖一项;新疆药学会科学技术奖三等奖一项;2014年获得中国共产党新疆维吾尔自治区委员会授予的第七批中央和国家机关、中央企业优秀援疆干部人才奖励;2017年获得中国药学会科学技术奖二等奖。
近年发表论文(2012年至今)
1. Hong Zhang, Erna Xun, Jiaxin Wang, Ge Chen, Tiexin Cheng, Wang Zhi*, Tengfei Ji*, Lei Wang*, Immobilization of Laccase for Oxidative Coupling of Trans-Resveratrol and Its Derivatives, Int. J. Mol. Sci., 13: 5998-6008, 2012.
2. Teng-Fei Ji, Jin Li, Chun-Hui Liang*, The Chemical constituents of the twigs of Ammpiptanthus nanus, Journal of Asian Natural Products Research, 15(4):332-336,2013.
3. Yangai Wang, Jianbo Yang, Aiguo Wang, Jie Ma, Jin Tian, Tengfei Ji*, Yalun Su*, Hydrolyzable tannins from Balanophora polyandra, Acta Pharmaceutica Sinica B,3 (1):46–50,2013.
4. Jie Ma, Teng-Fei Ji, Jian-Bo, Yang, Ai-Guo Wang,Ya-Lun Su, Three new phloroglucinol derivatives from Hypericum scabrum, Journal of Asian Natural Products Research, 14(5): 508-514, 2012.
5. Di-Zao Li, Cun-Ying Wang, Rui-Hua Liu, Yan-Ming Wang, Teng-Fei Ji*, Yu-Rong Li,Xian-Dao Pan,Synthesis and cytotoxicity of novel 20-O-linked homocampto- thecin ester derivatives as potent topoisomerase I inhibitors,Journal of Asian Natural Products Research,15(4):332-336, 2013.
6. Yangai Wang, Jin Ren, Jianbo Yang, Aiguo Wang, Tengfei Ji, Qinge Ma, Jin Tian, Yalun Su*. Hepatoprotective Prenylaromadendrane-Type Diterpenes from the Gum Resin of Boswellia carterii. J. Nat. Prod., 76(11): 2074-2079, 2013.
7. Qinge Ma, Jin Tian, Jianbo Yang, Aiguo Wang, Tengfei Ji, Yangai Wang, Yalun Su*. Bioactive Carbazole Alkaloids from Murraya koenigii (L.) Spreng. Fitoterpia, 87:1-6, 2013.
8. Jin Tian, Qinge Ma, Jianbo Yang, Aiguo Wang, Tengfei Ji, Yangai Wang, Yalun Su*. Hepatoprotective Phenolic Glycosides from Gymnema tingens. Planta Medica, 79(9): 761-767, 2013.
9. Qian Wei,Jian-Bo Yang,Jin Ren,Ai-Guo Wang,Teng-Fei Ji,Ya-Lun Su* Bioactive phthalides from Ligusticum sinense Oliv cv. Chaxiong[J]. Fitoterapia, 93:226-232,2014.
10. Jun Zhao, Fang Xu, Tengfei Ji*, Jin Li*, A New Spermdine From The Fruits of Lycium ruthenicum, Chemistry of Natural Compounds, 126(5):1-3, 2014.
11. Qin-Ge Ma, Yan-Gai Wang, Wen-Min Liu, Rong-Rui Wei, Jian-Bo Yang, Ai-Guo Wang, Teng-Fei Ji, Jin Tian, and Ya-Lun Su*, Hepatoprotective Sesquiterpenes and Rutinosides from Murraya koenigii (L.)Spreng, Journal of Agricultural and Food Chemistry , 62:4145-4151, 2014.
12. Lin Ma, Ai-Hua Yu, Li-Li Sun, Wan Gao, Meng-Meng Zhang, Ya-Lun Su, Hua Liu and Tengfei Ji*, Two New Bidesmoside Triterpenoid Saponins from the Seeds of Momordica charantia L. Molecules, 19(2), 2238-2246, 2014.
13. Lili Sun, Wan Gao, Mengmeng Zhang, Cheng Li, Aiguo Wang, Yalun Su, Tengfei Ji *, Composition and Antioxidant Activity of the Anthocyanins of the Fruit of Berberis heteropoda Schrenk, Molecules, 19,19078-19096, 2014.
14. Jian-Bo Yang, Ai-Guo Wang, Teng-Fei Ji and Ya-Lun Su*, Two new oligostilbenes from the stem of Parthenocissusquinquefolia ,Journal of Asian Natural Products Research, 16(3):717-723, 2014.
15. Chuang-Jun Li, Ling Yuan, Teng-FeiJi, Jian-Bo Yang, Ai-Guo Wang, Ya-Lun Su*, Furostanolsaponins from the seeds of Allium cepa L.,Fitoterapia, 99:56-63 ,2014.
16. Zhi Wang, Chun-Yu Wang, Hao-Ran Wang, Hong Zhang, Ya-Lun Su, Teng-Fei Ji*, Lei Wang*, Lipase-catalyzed Knoevenagel condensation between α,β-unsaturated aldehydes and active methylene compounds, Chinese Chemical Letters, 25(5):802-804, 2014.
17. Lin Ma, Ai-Hua Yu, Li-Li Sun, Wan Gao, Meng-Meng Zhang, Ya-Lun Su, Hua Liu, Teng-Fei Ji*, Di-Zao Li*, Two new cucurbitanetriterpenoids from the seeds of Momordica charantia, Journal of Asian Natural Products Research, 16(5): 476-482, 2014.
18. Jin-ying Tian, Rong-ya Tao, Xiao-lin Zhang, Qian Liu, Yi-bo He, Ya-lun Su, Teng-fei Ji*, Fei Ye*, Effect of Hypericum perforatum L. extract on insulin resistance and lipid metabolic disorder in high-fat-diet induced obese mice, Phytotherapy Research, 29:86-92, 2015.
19. Guo-Ping Zhou , Yan Yu , Ming-Ming Yuan, Tengfei Ji *, Hui-Zheng Fu, Rui-Jian Zhong *, Four New Triterpenoids from Callicarpa kwangtungensis, Molecules, 20, 9071-9083, 2015.
20. Wan Gao, Jia-Wen Hu, Fang Xu, Chan-Jing Wei, Meng-Jiao Shi, Jun Zhao, Jia-Jia Wang, Bo Zhen, Teng-Fei Ji*, Jian-Guo Xing, Zheng-Yi Gu* and Fang Xu*, Polyisoprenylated benzoylphloroglucinol derivatives from Hypericum scabrum, Fitoterapia,115: 128-134, 2016.
21. Wan Gao, Jia-Wen Hu, Wei-Zhen Hou, Fang Xu, Jun Zhao, Fang Xu, Hua Sun, Jian-Guo Xing,Ying Peng, Xiao-Liang Wang, Teng-Fei Ji*, Li Li* , Zheng-Yi Gu*, Four new prenylated phloroglucinol derivatives from Hypericum scabrum,Tetrahedron Lett.,57,2244-2248,2016.
22. Wan Gao, Wei-Zhen Hou, Jun Zhao, Fang Xu, Li Li, Fang Xu, Hua Sun, Jian-Guo Xing, Ying Peng, Xiao-Liang Wang, Teng-Fei Ji* and Zheng-Yi Gu*, Polycyclic Polyprenylated Acylphloroglucinol Congeners from Hypericum scabrum, J. Nat. Prod., 79 (6):1538–1547, 2016.
23. Di-Zao Li, Qiang-Zhe Zhanga, Cun-Ying Wang, Yan-Ling Zhang, Xing-Yu Li, Ji-Tao Huang, Hong-Yan Liu, Zhao-Di Fu, Hua-Xian Song, Jin-Ping Lin, Teng-Fei Ji*, Xian-Dao Pan*, Synthesis and antitumor activity of novel substituted uracil-1′(N)-acetic acid ester derivatives of 20(S)-camptothecins, European Journal of Medicinal Chemistry, 125:1235-1246,2017
24. Jihong Nie*, Fang Wang, Tengfei Ji*, Jun Zhao, Feicui Zhao,Assessment of in vitro cardiotoxicity of extract fractions and diterpene alkaloids from Aconitum leucostomum Worosch: A short communication,Journal of Pharmaceutical and Biomedical Analysis,137:84-89,2017.
25. Jun Zhao, Shilei Zhang, Shuping You, Tao Liu*, Fang Xu, Tengfei Ji*, Gu Zhengyi*,Hepatoprotective Effects of Nicotiflorin from Nymphaea candida against Concanavalin A - Induced and D-Galactosamine - Induced Liver Injury in Mice,Int. J. Mol. Sci., 18(3), 587; doi:10.3390/ijms**, 2017.
26. Jiawen Hu, Wan Gao, Fang Xu, Canjing Wei, Mengjiao Shi, Hua Sun, Bo Zhen, Jiajia Wang, Tengfei Ji*, Jiandong Jiang* ,Polycyclic polyprenylated acylphloroglucinol derivatives from Hypericum scabrum, Bioorg.Med. Chem. Lett.,27(21):4932-4936,2017.
近年专利
1. 专利名称:香茅属植物提取物作为胰岛素增敏药物的用途;专利申请号: 5.8。
2. 专利名称:金丝桃属提取物,其制法及其药物组合物与治疗糖尿病的用途;专利证书号:** ;专利申请号:9.9。
3. 专利名称:一种具有降血糖活性的中药提取物、制法、组合物与应用;专利证书号:766128;专利申请号:9.9。
4. 专利名称:洋芫荽子酸类化合物;专利申请号:8.4。


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