张占军
职称：医学博士,教授,博士生导师
研究领域 ：
电话：（8610）**
通讯地址：北京师范大学京师大厦1006室
邮编：100875
电子邮件：zhang_rzs#bnu.edu.cn
课题组网址：http://brain.bnu.edu.cn/home/zhangzhanjun/index.html

简 介
研究方向
研究人员
论文成果
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现任北京师范大学老年脑健康研究中心主任，脑与认知科学研究院副院长，国家基金获得者，于2005年获北京中医药大学临床医学院医学专业博士学位。在北京启动了老年脑健康计划BABRI（Beijing Aging Brain Rejuvenation Initiative, BABRI）计划，长 期从事人类高级认知功能的老化衰退规律及其脑机制研究，围绕人类高级认知功能的老化衰退规律及其脑机制这一个关键科学问题，深入研究人类老化进程中不同高 级认知能力的衰退模式与关键期、人脑结构功能网络的退化规律、遗传变异对脑与认知衰老的调控机制，以及中医药在防治老化中的脑保护作用。是全国百篇优秀博士论文获得者和教育部新世纪优秀人才计划的获得者，兼任中国老年医学会认知障碍分会、世界中医药联合会老年医学分会副会长。
主要研究方向为认知老化与认知障碍及中医药干预。以社区、医院认知损伤的病人（痴呆、轻度认知障碍、中风、糖尿病等）脑的高级认知功能为研究核心，结合基因、行为和影像多种技术方法，考察遗传、社区慢病对认知老化与障碍的影响及干预后的脑机制。

代表性论文：
Yaojing Chen, Peng Li, Bin Gu, Zhen Liu, Xin Li, Alan C Evans, Gaolang Gong, Zhanjun Zhang. (2014) The effects of an APOE promoter polymorphism on human cortical morphology during non-demented aging. The Journal of Neuroscience. Accepted.
Yaojing Chen, Zhen Liu, Junying Zhang, Kai Xu, Sisi Zhang, Dongfeng Wei,Zhanjun Zhang. (2014) Altered Brain Activation Patterns Under Different Working Memory Loads in Patients With Type 2 Diabetes. Diabetes Care. 37(12):3157-3163.
Yaojing Chen, Kewei Chen, Junying Zhang, Xin Li, Ni Shu, Jun Wang, Zhanjun Zhang, Eric M Reiman. (2014) Disrupted functional and structural networks in cognitively normal elderly subjects with the APOE ε4 allele. Neuropsychopharmacology. Accepted, doi:10.1038/npp.2014.302.
Junying Zhang, Yunxia Wang, Jun Wang, Xiaoqing Zhou, Ni Shu, Yongyan Wang,Zhanjun Zhang. (2014) White matter integrity disruptions associated with cognitive impairments in type 2 diabetes patients. Diabetes, 63(11):3596-3605.
Dongfeng Wei, Jinfu Tang, Weiguo Bai, Yongyan Wang, Zhanjun Zhang. (2014) Ameliorative Effects of Baicalein on an Amyloid-β Induced Alzheimer's Disease Rat Model: A Proteomics Study. Current Alzheimer Research, 11 (9):869-881.
Junying Zhang, Zijing Wang, Shijun Xu, Yaojing Chen, Kewei Chen, Li Liu, Yongyan Wang, Rongjuan Guo,Zhanjun Zhang. (2014) The effects of CCRC on cognition and brain activity in aMCI patients: a pilot placebo controlled BOLD fMRI study. Current Alzheimer Research,
Junying Zhang, Peng Li, Yanping Wang, Jianxun Liu,Zhanjun Zhang, Weidong Cheng, Yongyan Wang. (2013) Ameliorative Effects of a Combination of Baicalin, Jasminoidin and Cholic Acid on Ibotenic Acid-Induced Dementia Model in Rats. PloS one, 8(2):e56658.
Liang Wang, Ying Liang, He Li, Junying Zhang, Xin Li, Ni Shu, Yongyan Wang,Zhanjun Zhang.（2013）Topological reorganization of the default mode network in amnestic mild cognitive impairment. Radiology, 268 (1).
Ni Shu, Ying Liang, He Li, Junying Zhang, Xin Li, Liang Wang, Yong He, Yongyan Wang,Zhanjun Zhang. (2012) Disrupted Topological Organization in White Matter Structural Networks in Amnestic Mild Cognitive Impairment: Relationship to Subtype. Radiology 265(2): 518-527.
Jian Li, Runguo Wu, Fanyun Meng, Zhong Wang, Changming Wang, Yongyan Wang,Zhanjun Zhang. (2012) Synergism and Rules from Combination of Baicalin, Jasminoidin and Desoxycholic acid in Refined Qing Kai Ling for Treat Ischemic Stroke Mice Model. PloS one 7(9).