张富春

张富春 Zhang Fu-chun

博士、教授/副教授、博士生导师/硕士生导师



教育经历（按时间正排序）

1979/09 –1983/07，新疆大学，生物系毕业，学士学位

1986/09 –1989/07，兰州大学，生物系毕业，硕士学位

1992/09 –1995/06，中国农业大学，动物科技学院，博士学位



工作经历（科研与学术工作经历，按时间正排序）

1983/08 – 1986/08，新疆大学，生物系助教

1989/09 – 1992/08，新疆大学，生物系助教、讲师

1995/09 – 1997/09，中国科学院动物研究博士后

1997/10 – 2001/06，新疆大学生物系副教授、教授

2001/07 – 至今， 新疆大学生命科学与技术学院教授



主要研究方向及承担的科研项目

主要研究方向:

{C}1. {C}植物分子生物学-围绕新疆干旱环境特殊的盐生植物盐穗木、花花柴和主栽的农作物棉花，开展植物抗逆-抗旱耐盐的基因克隆、基因表达、生理生化特性分析、基因功能鉴定的相关研究。

{C}2. 分子免疫学-针对不同哺乳动物卵透明带3基因的克隆、表达载体构建、DNA疫苗设计、分子佐剂克隆与应用，抗血清制备、免疫剂量和免疫途径优化，DNA免疫不育疫苗抗生育的免疫效果验证等。



承担的科研项目:

{C}1. {C}国家自然科学基金-新疆联合基金重点支持项目 棉花水分高效利用关键基因的挖掘及抗旱材料创制（U**）2014-2017

{C}2. {C}自治区重点实验室专项经费 盐穗木盐胁迫响应的转录组研究及重要基因功能鉴定（2014KL001）2014-2016

{C}3. {C}国家“973”前期研究专项 新疆荒漠盐生植物耐盐的生理及分子机制（2012CB722204）2012-2014

{C}4. {C}自治区高技术发展计划项目 新疆家蚕抗菌肽工业发酵和医用消毒剂产品开发（**）2011-2013

{C}5. {C}国家自然科学基金 盐生植物花花柴耐盐和抗氧化分子机理的研究（**）2010-2012



主要论著（近5年代表性论著，限10篇）

{C}1. {C}Yan-Ling Wu, Li-Jie Xia, Jin-Yao Li And Fu-Chun Zhang. CecropinXJ inhibits the proliferation of human gastric cancer BGC823 cells and induces cell death in vitro and in vivo. Iternational journal of oncology, 2015, 46: 2181-2193.

2. Yijie Li,,Xinping Li, Huanhuan Liu, Shuzhen Zhuang, Jianhua Yang and Fuchun Zzhang﹡. Intranasal immunization with recombinant Lactococci carrying human papillomavirus E7 protein and mouse interleukin-12 DNA induces E7?specific antitumor effects in C57BL/6 mice. Oncology Letters.2014,7(2)：576-582.

3. Lijie Xia, Yanling Wu, SuKang,JiMa, JianhuaYang, and Fuchun Zhang﹡. CecropinXJ, a silkworm antimicrobial peptide, induces cytoskeleton disruption in esophageal carcinoma cells. Acta Biochim Biophys Sin,.2014.,26(10):867-876.

4. Lijie Xia, Zhongyuan Liu, Ji Ma, Surong Sun, Jianhua Yang, Fuchun Zhang. Expression, purification and characterization of Cecropin antibacterial peptide from Bombyx mori in Saccharomyces cerevisiae, protein expression and purification, 2013, Protein Expression and Purification. 2013, 90: 47-54 .

5. Lijie Xia, Zhongyuan Liu, Ji Ma, Jianhua Yang. Fuchun Zhang*. Expression and characterization of cecropinXJ, abioactive antimicrobial peptide from Bombyx mori (Bombycidae, Lepidoptera) in Escherichia coli. Experimental and Therapeutic Medicine,2013，5:1745-1751.

6.Zibirnisa Kadir,Xiaolin Ma,Jinyao Li,Fuchun Zhang.Granulocyte-Macrophage– Colony-Stimulating Factor Enhances the Humoral Immune Responses of Mouse Zona Pellucida 3 Vaccine Strategy Based on DNA and Protein Coadministration in BALB/c Mice. Reproductive Sciences. 2013, 20 （4）：400-407.

7.Ying-Hua Fu， Fu-Chun Zhang.Changes in isoflavone glucoside and aglycone contents of chickpea yoghurt during fermentation by Lactobacillus bulgaricus and Streptococcus thermophilus. Journal of Food Processing and Preservation. 2013,37: 744–750

8. Yongli Qiao, Lin Liu, Qin Xiong, Cristina Flores, James Wong, Jinxia Shi, Xianbing Wang, Xigang Liu, Qijun Xiang, Shushu Jiang, Fuchun Zhang, Yuanchao Wang, Howard S Judelson， Xuemei Chen, & Wenbo Ma. .Oomycete pathogens encode RNA silencing suppressors.nature genetics.2013,1-5.

9. Shengben Li, Lin Liu, Xiaohong Zhuang,Yu Yu, Xigang Liu,Xia Cui, Lijuan Ji, Zhiqiang Pan, Xiaofeng Cao,Beixin Mo, Fuchun Zhang, Natasha Raikhel, Liwen Jiang, and Xuemei Chen1*. MicroRNAs Inhibit the Translation of Target mRNAs on the Endoplasmic Reticulum in Arabidopsis. Cell 2013, 153:562–574.

10.Yixian Tu, Xinping Li, Zibirnisa Kadir, and Fuchun Zhang*.. Molecular adjuvant interleukin-33 enhances the antifertility effect of Lagurus laguruszona pellucida 3 DNA vaccine administered by the mucosal route. Brazilian Journal of Medical and Biological Research (2013) 46:1064-1073.



联系方式：

E-mail：zfcxju@xju.edu.cn 电话：**