Haixia Chen——Professor
Nationality:
CHINA

Phone:


Email:
chenhx@tju.edu.cn

Office:
Room C512, Building 24, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
K-1661-2015

Group weblink








Education Experience
1997-2002 Ph. D. Huazhong Agricultural University, CN
2002-2004 Postdoctoral Ocean University of China, CN

Professional Experience
2013- Professor Tianjin University
2004-2013 Associate Professor Tianjin University
2011-2012 Visiting scholar University of California, Berkeley
2002-2004 Postdoctoral fellow Ocean University of China

Research Area
The research of the Chen group concerns isolation, identification, bioactivity, and mechanism of constituents from natural resources. In particular, the group focuses on functional mechanism and structure-activity relationships of macromolecules (polysaccharides and proteins) as well as small biomolecules. Methods are being developed in the group to quantify bioactivity of polysaccharides and small biomolecules from Traditional Chinese Medicine and natural resources. Additionally, the group investigates functional food and new medicine from natural sources.
Her research would be helpful to the investigation and utilization of natural resources. She has been the Primary Investigator (PI) in 15 projects such as the funds from National Natural Science Foundation of China (NSFC), National High Technology Research and Development Program ("863"Program) of China, Project of National Key Technology Research and Development Program for The 12th Five-year Plan, National Program on Key Basic Research Project (973 Program). More than 100 research papers of Dr. Haixia Chen have been published, and73 of the papers are published on SCI/SCIE journals with Haixia Chen being the first author or correspondence author. She has participated in 8 published books. 35 Chinese patents have been applied and 17 of them were authorized. Her papers on the study of bioactive polysaccharides have been cited by many researchers around the world and the citation frequency reached 2200 times in SCI database with H index of 25. One of her paper has been cited more than 225 times at the end of April 2019. She has been the editorial board member of some journals such as EC Pharmacology and Toxicology, Journal of Food Safety & Quality, Pharmarceutical Journal of Chinese People’s Liberationl Armay. She has also been the reviewer of NSFC, MOST and MOE and many international journals and Chinese journals such as Frontiers in Pharmacology, Food Chemistry, Carbohydrate Polymers, International Journal of Biological Macromolecules, Food research international, Journal of Agricultural and Food Chemistry etc.



Honors and Awards
2018： Leader in Science and Technology Innovation of Tianjin City；
2015: The First Level of "131" Innovative Talent?of Tianjin City
2013: Peiyang Talent Foundation of Tianjin University
2012: Peiyang Talent Foundation of Tianjin University (Young faculty)
2010: Excellent Women Faculty of Tianjin University
2009: Ten Outstanding Young People (Teacher) of Tianjin University
2008: Excellent Teacher of Tianjin University on Teaching and Education
2008: THIRD-GRADE AWARD in lecturing contest of youth teacher of Tianjin City
2004: Excellent Doctoral Dissertation of Huazhong Agricultural University

Patents
1.Chen Haixia, Wang Jingya, Liu Wei, Chen Zhongqin, Hu Bo, Li Hongyi. A stable enteric sustained release tea polyphenol microcapsule and its preparation method, 2018.07.24 Chinese Patent, Patent No. 9.8
2.Chen Haixia, Wang Xiuming, Li Shuqin. A method for synthetically extracting active components from walnut, Chinese Patent, 2018.06.15, Patent No. .9
3.Chen Haixia, Xing Lisha, Wang Jia, Wang Yanwei. A method for preparing Green garlic, Chinese Patent, 2016.06.15, Patent No. 0.3
4.Chen Haixia, Wang Yanwei, Wang Jia, Xing Lisha. A method for preparation of Corn protein active Peptide by immobilized double enzyme with complex Carrier, Chinese Patent , 2015.06.17, Patent No. 6.3
5.Chen Haixia, Chen Shuhan, Tian Jingge. Preparation of Corn protein membrane with High Antioxidant Properties, Chinese Patent, 2015.08.19, Patent No. 6.6
6.Chen Haixia, Zhang Ning, Zhang Yu, Ma Lishuai, a method for synthetically obtaining active ingredients from Lentinus edodes, Chinese Patent, 2014.11.26, Patent No. .9
7.Chen Haixia, Zhang Yu, Zhang Ning, Ma Li Shuai. A method for extracting active proteins with Antioxidant and hypoglycemic effects from Lentinus edodes, Chinese Patent, 2013.03.06, Patent No. 9.0
8.Chen Haixia, Ma Li Shuai, Zhang Ning, Zhang Yu. A synthetic method for the extraction of steroids, polysaccharides and polyphenols from Betula obliquus, Chinese Patent, 2013.11.27, Patent No.2.7
9.Chen Haixia, Zhang Xin, Fu Lingling, Dong Peng. A method for extracting Tea polysaccharides and Tea polyphenols from coarse Green Tea, Chinese Patent, 2011.02.09, Patent No.5.0
10.Chen Haixia, Lu Xueming. Preparation method of Betula obliquus extract as an inhibitor of α -glucosidase, Chinese Patent, 2011.04.06, Patent No. 200810 152916.3
11.Chen Haixia, Lan Gao Shuang. A Jade Bamboo Hawthorn Apple compound drink and its preparation method, Chinese Patent, 2012.07.04, Patent No. 5.4

Highlighted Publications
Gao XD, Wang C, Chen ZQ, Chen Y, Santhanam R K, Xue ZH,Ma QQ, Guo QW, Liu W, Zhang M, Chen HX*. Effects of N-trans-feruloyltyramine isolated from laba garlic on antioxidant, cytotoxic activities and H2O2-induced oxidative damage in HepG2 and L02 cells. Food and Chemical Toxicology, 2019, 130, 130-141.
Xue ZH, Chen Y, Jia YN, Wang YJ, Lu YP, Chen HX*, Zhang M*. Structure, thermal and rheological properties of different soluble dietary fiber fractions from mushroom Lentinula edodes (Berk.) Pegler residues. Food Hydrocolloids. Food Hydrocolloids,2019 ,95, 10-18
Guo QW, Xu LL, Chen Y, Ma QQ, Santhanam RK, Xue ZH, Gao XD, Chen HX*.Structural characterization of corn silk polysaccharides and its effect in H2O2?induced oxidative damage in L6 skeletal muscle cells. Carbohydrate Polymers. 2019, 208,? 161-167
Chen ZQ ,Wang C, Gao XD , Chen Y, Santhanam R K ,Wang CL, Xu LL, Chen HX*. Interaction characterization of preheated soy protein isolate with cyanidin- 3-O-glucoside and their effects on the stability of black soybean seed coat anthocyanins extracts. Food Chemistry, 2019,271, 266–273
Guo QW, Chen ZQ, Santhanam RK, Xu LL, Gao XD, Ma QQ, Xue ZH, Chen HX*. Hypoglycemic effects of polysaccharides from corn silk (Maydis stigma) and their beneficial roles via regulating the PI3K/Akt signaling pathway in L6 skeletal muscle myotubes，International Journal of Biological Macromolecules, 2019, 121 , 981–988

ResearcherID Publications
Year Title Author(s) Source Volume
2005 4,5,9,14-tetramethyl-19-norcholest-24-en-3-one Liu, KY; Gao, WY; Zhang, TJ; et al. Acta Crystallographica Section E-Structure Reports Online 61
2006 Studies on the physicochemical, morphological, thermal and crystalline properties of starches separated from different Dioscorea opposita cultivars Wang, SJ; Gao, WY; Liu, HY; et al. Food Chemistry 99
2006 Studies on the morphological, thermal and crystalline properties of starches separated from medicinal plants Wang, Shujun; Gao, Wenyuan; Chen, Haixia; et al. Journal of Food Engineering 76
2006 Effects of a glycoconjugate from Lycium barbarum on body composition in growing mice Zhang, M; Chen, HX Journal of the Science of Food and Agriculture 86
2006 Characterization of new starches separated from different Chinese yam (Dioscorea opposita Thunb.) cultivars Wang, SJ; Liu, HY; Gao, WY; et al. Food Chemistry 99
2006 1-[(2-Chlorophenyl)(4-chlorophenylimino)-methyl] ferrocene Zhang, Y; Gao, WY; Chen, HX Acta Crystallographica Section E-Structure Reports Online 62
2007 The effect of acid hydrolysis on morphological and crystalline properties of rhizoma Dioscorea starch Wang Shujun; Yu Jinglin; Yu Jiugao; et al. Food Hydrocolloids 21
2007 Compositional analysis and preliminary toxicological evaluation of a tea polysaccharide conjugate Chen, Haixia; Zhang, Min; Qu, Zhishuang; et al. Journal of Agricultural and Food Chemistry 55
2007 5-(2,3-dihydroxy-3-methylbutoxy)-7H-furo[3,2-g]chromen-7-one Deng, Ke-Zhong; Gao, Wen-Yuan; Xiong, Ying; et al. Acta Crystallographica Section E-Structure Reports Online 63
2007 5,6-dihydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3,4]cycloocta[1,2-f][1,3]-benzodioxol-5-yl benzoate sesquihydrate Xiong, Ying; Gao, Wen-Yuan; Deng, Ke-Zhong; et al. Acta Crystallographica Section E-Structure Reports Online 63