Yunfei Du ——Professor
Nationality:
CHINA

Phone:


Email:
duyunfeier@tju.edu.cn

Office:
Room A208, Building 24, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
K-3776-2015

Group weblink








Education Experience
2007 Ph. D. Tianjin University, CN

Professional Experience
2007-2009 Assistant Professor Tianjin University.
2009-2013 Associate Professor Tianjin University
2012-2019 Associate Dean / Party Vice-Secretary Tianjin University
2013-2019 Professor Tianjin University
2019- Associate Dean Tianjin U

Research Area
The research area of the Du group involves investigation of hypervalent iodine (III) – mediated transformations, including oxidative coupling, rearrangement, cascade reactions, and asymmetric reactions. Additionally, the group develops metal-free methodology for the constructionof heterocyclic compounds and pharmaceutical agents.




Honors and Awards
四乙酰核糖和二乙酰阿昔洛韦合成的新工艺，天津市人民政府，科技进步奖，二等奖，2010。（赵康、陈维瑜、魏静、杜云飞、王松青、苏艳芳、张秀东、陈炎泉）
第十二届“挑战杯”天津市大学生课外学术科技作品竞赛优秀指导教师，天津市委员会、天津市科学技术委员会、天津市教育工作委员会等，优秀指导教师，2013。（杜云飞）
天津大学“北洋青年****”，2015年。
天津市“131”创新型人才培养工程第一层次人选，2016年。

Patents
杜云飞，袁玉成，赵康，一种通过C–N氧化偶联合成取代二氨基烯烃衍生物的方 法，中国，20**
杜云飞，程然，赵康，一种通过环合消除一锅法合成4（3H）-喹唑啉酮衍生物的 方法，中国，5.0。
杜云飞，程然，赵康，一种通过环合消除一锅法合成4（3H）-喹唑啉酮衍生物的 方法，中国，5.0。
杜云飞，尚巳耘，赵康，一种合成二苯并二氢-1,3-二氮杂?类衍生物的方法， 中国，4.8。
杜云飞，吕晶磊，赵康，一种2-吲哚酮-3-羧酸酯类衍生物的合成方法，中国，2 .2。
杜云飞，李旭明，张翔，赵康，一种二苯西平类衍生物的合成方法，中国，2.1。
杜云飞，吕晶磊，尚巳耘，赵康，一种四氢-γ-咔啉类衍生物的合成方法，中 国，8.4。
杜云飞，刘乐，贺巧巧，赵康，1,3-二腈基2-取代-1H-茚类衍生物及其制备方 法，中国，9.1。
杜云飞，赵康，赵菲菲，刘昕，齐蕊，2-三氟甲基噁唑类衍生物的合成方法， 中国，8.7。
杜云飞，云希柳，毕文英，赵康，一种氮取代四氢咔唑酮衍生物的制备新方法 ，中国，3.0。
祁秀香，杜云飞，闫俏，赵康，李慧，合成N-芳基吲哚-3-腈衍生物的方法，中 国，3.2。
杜云飞，汤丽娜，庞永乐，阎俏，祁秀香，一种合成Coumestan类衍生物的新方 法，中国，9.0。
杜云飞，马辉，赵康，异吲哚啉羧酸酯衍生物的制备方法及其应用，中国，8.1。

Highlighted Publications
Shang, S.; Zhang-Negrerie, D.; Du, Y.;* Zhao, K.* Intramolecular Metal-free Oxidative Aryl-aryl Coupling: An Unusual Hypervalent Iodine-mediated Rearrangement of 2-Substituted N-Phenylbenzamides. Angew. Chem., Int. Ed. 2014, 53, 6216. (Hot Paper)
Yu, J.; Zhang-Negrerie, D.; Du, Y.* Cu(OAc)2-Mediated Cascade Annulation of Diarylalkyne Sulfonamides through Dual C-N Bond Formation: Synthesis of 5,10-Dihydroindolo[3,2-b]indoles. Org. Lett. 2016, 18, 3322–3325.
Cao, Y.; Zhang, X.; Lin, G.; Zhang-Negrerie, D.; Du, Y.* Chiral Aryliodine-Mediated Enantioselective Organocatalytic Spirocyclization: Synthesis of Spirofurooxindoles via Cascade Oxidative C-O and C-C Bond Formation. Org. Lett. 2016, 18, 5580–5583.
Zhang, B.; Zhang,X.; Hu, B.; Sun, D.; Wang, S.; Zhang-Negrerie, D.; Du. Y.* PhI(OCOCF3)2-Mediated Construction of 2-Spiropseudoindoxyl Skeleton via Cascade Annulation of 2-Sulfonamido-N-phenylpropiolamide Derivatives. Org. Lett. 2017, 19, 902.
Zhao, X.; Li, Q.; Xu, J.; Wang, D.; Zhang-Negrerie, D.; Du, Y.* Cascade Synthesis of Benzothieno[3,2-b]indoles Under Oxidative Conditions Mediated by CuBr and tert-Butyl Hydroperoxide. Org. Lett. 2018, 20, 5933-5937.

ResearcherID Publications
Year Title Author(s) Source Volume
2013 Formation of Functionalized 2H-Azirines through PhIO-Mediated Trifluoroethoxylation and Azirination of Enamines Sun, Xiaoqian; Lyu, Youran; Zhang-Negrerie, Daisy; et al. Organic Letters 15
2013 Direct Conversion of N-Alkoxyamides to Carboxylic Esters through Tandem NBS-Mediated Oxidative Homocoupling and Thermal Denitrogenation Zhang, Ningning; Yang, Rui; Zhang-Negrerie, Daisy; et al. Journal of Organic Chemistry 78
2013 Control of Regioselectivity and Stereoselectivity in (4 3) Cycloadditions of Chiral Oxyallyls with Unsymmetrically Disubstituted Furans Du, Yunfei; Krenske, Elizabeth H.; Antoline, Jennifer E.; et al. Journal of Organic Chemistry 78
2013 Constructions of tetrahydro-gamma-carboline skeletons via intramolecular oxidative carbon-carbon bond formation of enamines Lv, Jinglei; Li, Ji; Zhang-Negrerie, Daisy; et al. Organic & Biomolecular Chemistry 11
2014 The applications of hypervalent iodine(III) reagents in the constructions of heterocyclic compounds through oxidative coupling reactions Zheng ZiSheng; Zhang-Negrerie, Daisy; Du YunFei; et al. Science China-Chemistry 57
2014 Synthesis of substituted tetrahydron-1H-carbazol-1-one and analogs via PhI(OCOCF3)(2)-mediated oxidative C-C bond formation Shi, Hao; Guo, Tianjian; Zhang-Negrerie, Daisy; et al. Tetrahedron 70
2014 PhICl2 Mediated Conversion of Enamines into alpha,N-Dichloroimines and Their Reverse Conversion Mediated by Zinc in Methanol Tang, Linlin; Zhang-Negrerie, Daisy; Du, Yunfei; et al. Synthesis-Stuttgart 46
2014 PhICl2 and Wet DMF: An Efficient System for Regioselective Chloroformyloxylation/alpha-Chlorination of Alkenes/alpha,beta-Unsaturated Compounds Liu, Le; Zhang-Negrerie, Daisy; Du, Yunfei; et al. Organic Letters 16
2014 PhI(OCOCF3)(2)-Mediated Intramolecular Oxidative N-N Bond Formation: Metal-Free Synthesis of 1,2,4-Triazolo[1,5-a]pyridines Zheng, Zisheng; Ma, Shuangyu; Tang, Linlin; et al. Journal of Organic Chemistry 79
2014 PhI(OAc)(2)-Mediated Intramolecular Oxidative Aryl-Aldehyde Csp(2)-Csp(2) Bond Formation: Metal-Free Synthesis of Acridone Derivatives Zheng, Zisheng; Dian, Longyang; Yuan, Yucheng; et al. Journal of Organic Chemistry 79