西安交通大学生命科学与技术学院导师教师师资介绍简介-宗瑜瑾

删除或更新信息，请邮件至freekaoyan#163.com(#换成@)

本站小编 Free考研考试/2021-06-26

个人主页 - 宗瑜瑾基本信息

宗瑜瑾
教授，博导
生物医学影像与应用研究所，副所长

联系方式
办公室：教二楼北107s室/创新港泓生楼(18号楼)3073室
通信地址： 西安交通大学生命科学与技术学院，西安市咸宁西路28号
邮编：710049
电话：**-805
电子邮箱：yjzong@xjtu.edu.cn

站点计数器

个人简介
西安交通大学生命科学与技术学院教授，博士生导师。2006年毕业于西安交通大学，获生物医学工程专业博士学位，2015年2月-2016年1月在美国华盛顿大学工业与医学超声中心作访问****。现任西安交通大学生物医学影像与应用研究所副所长。
主要研究方向：
超声造影成像、超分辨成像；
图像引导的超声基因/药物递送
多模造影剂及其诊疗应用

主讲研究生课程“波动理论及其医学应用”。近年来主持国家级科研项目6项，包括国家重点研发计划项目课题1项、国家自然科学基金面上项目5项；作为骨干人员参与国家重大科学仪器研制项目1项、国家重点研发计划项目课题1项、973项目课题1项，发表SCI论文40余篇，授权发明专利4项，作为副主编出版教材2部，撰写出版英文专著1章，作为主要完成人获陕西省科技进步一等奖1项，参与完成的研究成果入选“2017年中国医学十大进展”。现任中国超声医学工程学会第八届仪器工程开发专委会副主任委员，陕西省超声医学工程学会常委，中国超声医学工程学会超声治疗及生物效应专委会、分子影像专委会委员。

近五年科研项目

没有找到条目。

项目编号项目名称项目来源起讫时间承担角色项目类别
** 肿瘤微血管内外微泡和相变液滴定位复合超分辨超声成像及其引导的液滴介导药物递送国家自然科学基金项目 2021-1~ 负责人纵向项目
** 超声脑小血管超分辨及动态多参量成像系统国家重大科研仪器研制项目 2019-1~ 骨干成员纵向项目
** 超声/磁场对双峰分布双模相变纳米液滴的协同操控及其在肿瘤诊疗中的应用国家自然科学基金项目 2018-1~ 负责人纵向项目
2016YFC** 经颅血脑屏障开放/溶栓三维微泡与空化超声成像及诊疗系统国家重点研发计划项目课题 2016-6~ 负责人纵向项目

招生信息
本课题组常年招收生物医学工程、生物物理学专业硕士和博士研究生，欢迎生物医学工程、材料、生物、化学等相关专业的有志青年报考。
常年招收生物医学工程、电子信息、材料、生物和化学等领域的优秀博士后研究人员。

研究领域 - 宗瑜瑾主要研究领域

科研项目

1. 国家自然科学基金面上项目（**），肿瘤微血管内外微泡和相变液滴定位复合超分辨超声成像及其引导的液滴介导药物递送，2021.01-2024.12，61万元，在研，主持
2. 国家重大科研仪器研制项目 (**)，超声脑小血管超分辨及动态多参量成像系统，2019.01-2023.12，796.72万元，在研，主要参加
3. 国家自然科学基金面上项目（**），超声/磁场对双峰分布相变纳米液滴的协同操控及其在肿瘤诊疗中的应用，2018.01-2021.12，58万元，在研，主持
4. 国家重点研发计划课题（2016YFC**）,经颅血脑屏障开放/溶栓三维微泡与空化超声成像及诊疗系统,2016.07-2018.12, 80万元，已结题，主持
5. 国家自然科学基金面上项目（**），基于可控空化内皮损伤的动脉粥样硬化斑块动物模型及其活体评价，2015.01-2018.12，85万元，已结题，主持。
6. 国家自然科学基金面上项目（**），基于血管内膜超声微泡空蚀的局部可控易损斑块动物模型建立及活体评价方法，2013.01-2013.12，15万元，已结题，主持。
7. 国家973项目课题（2010CB732603），易损斑块无创、高分辨超声功能与分子定量成像，2010.01-2014.08，396万元，已结题，主要参加。
8. 国家自然科学基金面上项目（**），深部稀疏微小血管及管内单泡超宽带超声灌注成像，2008.01-2010.12，25万元，已结题，主持。

科研奖励
1、获2016年度陕西省科学技术奖一等奖
2、参与完成的研究成果入选“2017年中国医学十大进展”

科研成果
BOOKS
1. 万明习，宗瑜瑾，王素品，生物医学超声学，北京：科学出版社，2010
2. 万明习，宗瑜瑾，王素品，陆明珠，生物医学超声实验，西安：西安交通大学出版社，2010
3.Yujin Zong, Shanshan Xu, Tom Matula, Mingxi Wan, Chapter 5. Cavitation-enhanced mechanical effects and applications, in book: Cavitation in Biomedicine, Principles and Techniques, Editor: M.Wan, Y. Feng, Gail ter Haar, Springer, 2015

RECENT PUBLISHED JOURNAL ARTICLES:
1.Wei Dong, Pengying Wu, Di Zhou, Jixiu Huang, Mengfan Qin, Xinxing Yang, Mingxi Wan, andYujin Zong*, Ultrasound-Mediated Gene Therapy of Hepatocellular Carcinoma Using Pre-microRNA Plasmid-Loaded Nanodroplets, Ultrasound in Med. & Biol., 2020, 46(1): 90-107
2.Pengying Wu, Yue Sun, Wei Dong, Huige Zhou, Shifang Guo, Lei Zhang, Xiaobing Wang*, Mingxi Wan* andYujin Zong*, Enhanced anti-tumor e?cacy of hyaluronic acid modi?ed nanocomposites combined with sonochemotherapy against subcutaneous and metastatic breast tumors, Nanoscale, 2019, 11, 11470
3.Pengying Wu, Wei Dong, Xuyan Guo, Xiaoyang Qiao, Shifang Guo, Lei Zhang,Mingxi Wan*, andYujin Zong*, ROS-Responsive Blended Nanoparticles: CascadeAmplifying Synergistic Effects of Sonochemotherapy with On-demand Boosted Drug Release During SDT Process, Adv. Healthcare Mater. 2019, 8, **
4.Shifang Guo, Xuyan Guo, Xin Wang, Di Zhou, Xuan Du, Meng Han,Yujin Zong*, Mingxi Wan*,Reduced clot debris size in sonothrombolysis assisted with phase-change nanodroplets, Ultrasonics Sonochemistry, 2019, 54:183-191
5.Shukuan Lu, Xianbo Yu, Renyan Li,Yujin Zong*, Mingxi Wan*, Passive cavitation mapping using dual apodization with cross-correlation in ultrasound therapy monitoring, Ultrasonics Sonochemistry, 2019, 54: 18-31
6.Shanshan Xu, Nan Chang, Rui Wang, Xiaodong Liu, Shifang Guo, Supin Wang,Yujin Zong*, Mingxi Wan*, Acoustic droplet vaporization and inertial cavitation thresholds and efficiencies of nanodroplets emulsions inside the focused region using a dual-frequency ring focused ultrasound, Ultrasonics Sonochemistry, 2018, 48: 532–537
7.Bai Chen, Mengling Ji, Ayache Bouakaz,Yujin Zong*, and Mingxi Wan*, Design and Characterization of an Acoustically and Structurally Matched 3-D-Printed Model for Transcranial Ultrasound Imaging, IEEE Trans on UFFC, 2018, 65(5): 741-748
8.Dui Qin, Lei Zhang, Nan Chang, Pengying Ni,Yujin Zong, Ayache Bouakaz, Mingxi Wan*, Yi Feng*, In situ observation of single cell response to acoustic droplet vaporization: Membrane deformation, permeabilization, and blebbing, Ultrasonics Sonochemistry, 2018, 47: 141–150
9.Shukuan Lu, Hong Hu, Xianbo Yu, Jiangying Long, Bowen Jing,Yujin Zong*, Mingxi Wan*,Passive acoustic mapping of cavitation using eigenspace-based robust Capon beamformer in ultrasound therapy, Ultrasonics Sonochemistry, 2018, 41: 670-679
10.Diya Wang, Mengnan Xiao, Hong Hu, Yu Zhang, Zhe Su, Shanshan Xu,Yujin Zong, Mingxi Wan, DCEUS-based focal parametric perfusion imaging of microvessel with single-pixel resolution and high contrast, Ultrasonics, 2018, 84: 392-403
11.Gao Xing, NanYang, Yuan Yuan, Gong Xue, Sun Yuanyuan, Zhou Huihui, Zong Yujin, Zhang Lijun, Yu Ming, Gas-filled ultrasound microbubbles enhance the immunoactivity of the HSP70-MAGEA1 fusion protein against MAGEA1-expressing tumours，Molecular Medicine Reports, 2018, 18(1):315-32112.
12. Xiaoping Xi,Yujin Zong, Yanghong Li, Bing Wang, Huasheng Liu, Experiment research of focused ultrasound combined with drug and microbubble for treatment of central nervous system leukemia, Oncotarget, 2018, 9(4):5424-5434
13.Shifang Guo, Aiwei Shi, Shanshan Xu, Xuan Du, Xin Wang,Yujin Zong, Ayache Bouakaz, and Mingxi Wan, Lowering of acoustic droplet vaporization threshold via aggregation, Appl. Phys. Lett., 2017, 111: 254102
14.Diya Wang,Yujin Zong, Xuan Yang, Hong Hu, Jinjin Wan, Lei Zhang, Ayache Bouakaz, Mingxi Wan, Ultrasound Contrast Plane Wave Imaging Based on Bubble Wavelet Transform:in vitroandin vivoValidations, Ultrasound in Medicine & Biology, 2016,42(7): 1584-1597
15.J. Hu^#,Y. Zong^#, J. Li, X. Zhou, J. Zhang, T. Zhu, M. Jiao, H. Su*, B. Bo*, InVitro and In Vivo Evaluation of Targeted Sunitinib-Loaded Polymer Microbubbles against Proliferation of Renal Cell Carcinoma, Journal of Ultrasound in Medicine, 2016, 35: 589-597.
16.A. Shi, P. Huang, S. Guo, L. Zhao, J. Jia,Y. Zong*, M. Wan*, Precise spatial control of cavitation erosion in a vessel phantom by using an ultrasonic standing wave, Ultrasonics Sonochemistry, 2016, 31: 163-172.
17.J. Tan, B. Pham,Y. Zong, C. Perez, D. Maris, A. Hemphill, C. Miao, T. Matula, P. Mourad, H. Wei, D. Sellers, P. Horner*, S. Pun*, Microbubbles and Ultrasound Increase Intraventricular Polyplex Gene Transfer to the Brain, Journal of Controlled Release, 2016, 231:86-93.

CONFERENCES:
1. Yujin Zong，Gang Liu，Jiangying Long，Di Zhou，Lei Zhang，Feng Yi，Mingxi Wan(*)，Focused ultrasound cavitation induced injury and localized atherosclerosis plaques of rabbit abdominal arterial endothelium，2017 IEEE International Ultrasonics Symposium, Washington.
2.Y. Zong, R. Wang, X. Zou, L. Zhang, G. Liu, and M. Wan*, “Local cavitation induced vessel wall injury of artery and its potential application in animal model of atherosclerosis,” IEEE International Ultrasonics Symposium, Taipei, Oct. 21-24, 2015.
3.Y. Zong, X. Zou, R. Wang, Y. Feng, M. Wan*, Ultrasound-enhanced extravasation of multifunctional nanodroplets from leaky vessel, IEEE Ultrasonics Symposium (IUS), IEEE International Ultrasonics Symposium, Taipei, Oct. 21-24, 2015
4.Y.J. Zong, J.J. Wan,MX. Wan. (2014) Non-invasive assessment of mechanical and hemodynamic parameters of carotid artery and plaque,International conference on biomedical ultrasound, (Shenzhen)
5.YJ. Zong, N. Zheng, SS Xu, MX. Wan.(2013)Low intensity focused ultrasound triggered local drug delivery from liposome-loaded microbubbles,International Society for Therapeutic Ultrasound Symposium (Shanghai)

科研团队 - 宗瑜瑾团队名称
学科带头人：万明习教授(生物医学工程学科领军****)

研究平台

研究队伍

招生信息 - 宗瑜瑾招生信息

常年招收生物医学工程、生物物理学专业博士研究生，欢迎生物医学工程、电子信息、物理、材料、生物和化学等领域的考生与课题组联系申请！！招收相关领域的博士后研究人员，期待你的加入!
常年招收生物医学工程、生物物理学专业硕士研究生，欢迎生物医学工程、电子信息、物理、材料、生物、化学等相关专业的毕业生报考。
考试科目：

English - 宗瑜瑾INFORMATION
Yujin Zong, Ph.D.
Professor, Department of Biomedical Engineering
Xian Jiaotong University, Beilin District, Xi’an, 710049, China
Office: Room 107s Jiao-Er Building
Tel: +86--805
Fax: +86--801
Email: yjzong@xjtu.edu.cn

GRANTS

PI
1. Super-broadband ultrasound perfusion imaging of deep microvascular and single bubble within the vascular, 2008-2010, National Nature Science Foundation of China (No. **).
2. Study on the methods of building local plaque animal modal based on ultrasound cavitation endothelium damage, 2013, National Nature Science Foundation of China (No. **)
3. Atherosclerosis animal model based on controlled ultrasound cavitation endothelial injury and its in vivo evaluation, 2015-2018, National Nature Science Foundation of China (No. **)
4.

Co-PI
1. Noninvasive and high resolution ultrasound functional and molecular quantitative imaging of vulnerable plaque, National Basic Research Program 973 (No. 2010CB732603) from Ministry of Science and Technology, 2010-2014
2. Drug-carried microparticles or Microbubbles, Locallized Controlled Release by Low Intensity Focused Ultrasound (LIFU) and Real-time Monitoring Imaging, State Key Program of National Natural Science of China (No. **).

Education
2006 Ph.D. in Biomedical Engineering
Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University, China
2000 M.S. in Material Engineering
School of Materials Science & Engineering, Xian Jiaotong University, China
1995 B.S. in Chemical Engineering
Dept. Chemical Engineering, Qingdao University of Science and Technology

Research Experience
2006-08 Research assistant, Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University
2008-14 Associate Professor, Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University
2015-16 Visiting Scholar, Center of Medical and Industrial Ultrasound, Applied Physics Laboratory, University of Washinton, Seattle
2016-19 Associate Professor, Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University
2020- Professor, Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University

Publications
BOOKS
1. 万明习，宗瑜瑾，王素品，生物医学超声学，北京：科学出版社，2010
2. 万明习，宗瑜瑾，王素品，陆明珠，生物医学超声实验，西安：西安交通大学出版社，2010
3.Yujin Zong, Shanshan Xu, Tom Matula, Mingxi Wan, Chapter 5. Cavitation-enhanced mechanical effects and applications, in book: Cavitation in Biomedicine, Principles and Techniques, Editor: M.Wan, Y. Feng, Gail ter Haar, Springer, 2015

RECENT PUBLISHED JOURNAL ARTICLES:
1.Wei Dong, Pengying Wu, Di Zhou, Jixiu Huang, Mengfan Qin, Xinxing Yang, Mingxi Wan, andYujin Zong*, Ultrasound-Mediated Gene Therapy of Hepatocellular Carcinoma Using Pre-microRNA Plasmid-Loaded Nanodroplets, Ultrasound in Med. & Biol., 2020, 46(1): 90-107
2.Pengying Wu, Yue Sun, Wei Dong, Huige Zhou, Shifang Guo, Lei Zhang, Xiaobing Wang*, Mingxi Wan* andYujin Zong*, Enhanced anti-tumor e?cacy of hyaluronic acid modi?ed nanocomposites combined with sonochemotherapy against subcutaneous and metastatic breast tumors, Nanoscale, 2019, 11, 11470
3.Pengying Wu, Wei Dong, Xuyan Guo, Xiaoyang Qiao, Shifang Guo, Lei Zhang,Mingxi Wan*, andYujin Zong*, ROS-Responsive Blended Nanoparticles: CascadeAmplifying Synergistic Effects of Sonochemotherapy with On-demand Boosted Drug Release During SDT Process, Adv. Healthcare Mater. 2019, 8, **
4.Shifang Guo, Xuyan Guo, Xin Wang, Di Zhou, Xuan Du, Meng Han,Yujin Zong*, Mingxi Wan*,Reduced clot debris size in sonothrombolysis assisted with phase-change nanodroplets, Ultrasonics Sonochemistry, 2019, 54:183-191
5.Shukuan Lu, Xianbo Yu, Renyan Li,Yujin Zong*, Mingxi Wan*, Passive cavitation mapping using dual apodization with cross-correlation in ultrasound therapy monitoring, Ultrasonics Sonochemistry, 2019, 54: 18-31
6.Shanshan Xu, Nan Chang, Rui Wang, Xiaodong Liu, Shifang Guo, Supin Wang,Yujin Zong*, Mingxi Wan*, Acoustic droplet vaporization and inertial cavitation thresholds and efficiencies of nanodroplets emulsions inside the focused region using a dual-frequency ring focused ultrasound, Ultrasonics Sonochemistry, 2018, 48: 532–537
7.Bai Chen, Mengling Ji, Ayache Bouakaz,Yujin Zong*, and Mingxi Wan*, Design and Characterization of an Acoustically and Structurally Matched 3-D-Printed Model for Transcranial Ultrasound Imaging, IEEE Trans on UFFC, 2018, 65(5): 741-748
8.Dui Qin, Lei Zhang, Nan Chang, Pengying Ni,Yujin Zong, Ayache Bouakaz, Mingxi Wan*, Yi Feng*, In situ observation of single cell response to acoustic droplet vaporization: Membrane deformation, permeabilization, and blebbing, Ultrasonics Sonochemistry, 2018, 47: 141–150
9.Shukuan Lu, Hong Hu, Xianbo Yu, Jiangying Long, Bowen Jing,Yujin Zong*, Mingxi Wan*,Passive acoustic mapping of cavitation using eigenspace-based robust Capon beamformer in ultrasound therapy, Ultrasonics Sonochemistry, 2018, 41: 670-679
10.Diya Wang, Mengnan Xiao, Hong Hu, Yu Zhang, Zhe Su, Shanshan Xu,Yujin Zong, Mingxi Wan, DCEUS-based focal parametric perfusion imaging of microvessel with single-pixel resolution and high contrast, Ultrasonics, 2018, 84: 392-403
11.Gao Xing, NanYang, Yuan Yuan, Gong Xue, Sun Yuanyuan, Zhou Huihui, Zong Yujin, Zhang Lijun, Yu Ming, Gas-filled ultrasound microbubbles enhance the immunoactivity of the HSP70-MAGEA1 fusion protein against MAGEA1-expressing tumours，Molecular Medicine Reports, 2018, 18(1):315-32112.
12. Xiaoping Xi,Yujin Zong, Yanghong Li, Bing Wang, Huasheng Liu, Experiment research of focused ultrasound combined with drug and microbubble for treatment of central nervous system leukemia, Oncotarget, 2018, 9(4):5424-5434
13.Shifang Guo, Aiwei Shi, Shanshan Xu, Xuan Du, Xin Wang,Yujin Zong, Ayache Bouakaz, and Mingxi Wan, Lowering of acoustic droplet vaporization threshold via aggregation, Appl. Phys. Lett., 2017, 111: 254102
14.Diya Wang,Yujin Zong, Xuan Yang, Hong Hu, Jinjin Wan, Lei Zhang, Ayache Bouakaz, Mingxi Wan, Ultrasound Contrast Plane Wave Imaging Based on Bubble Wavelet Transform:in vitroandin vivoValidations, Ultrasound in Medicine & Biology, 2016,42(7): 1584-1597
15.J. Hu^#,Y. Zong^#, J. Li, X. Zhou, J. Zhang, T. Zhu, M. Jiao, H. Su*, B. Bo*, InVitro and In Vivo Evaluation of Targeted Sunitinib-Loaded Polymer Microbubbles against Proliferation of Renal Cell Carcinoma, Journal of Ultrasound in Medicine, 2016, 35: 589-597.
16.A. Shi, P. Huang, S. Guo, L. Zhao, J. Jia,Y. Zong*, M. Wan*, Precise spatial control of cavitation erosion in a vessel phantom by using an ultrasonic standing wave, Ultrasonics Sonochemistry, 2016, 31: 163-172.
17.J. Tan, B. Pham,Y. Zong, C. Perez, D. Maris, A. Hemphill, C. Miao, T. Matula, P. Mourad, H. Wei, D. Sellers, P. Horner*, S. Pun*, Microbubbles and Ultrasound Increase Intraventricular Polyplex Gene Transfer to the Brain, Journal of Controlled Release, 2016, 231:86-93.

CONFERENCES:
1. Yujin Zong，Gang Liu，Jiangying Long，Di Zhou，Lei Zhang，Feng Yi，Mingxi Wan(*)，Focused ultrasound cavitation induced injury and localized atherosclerosis plaques of rabbit abdominal arterial endothelium，2017 IEEE International Ultrasonics Symposium, Washington.
2.Y. Zong, R. Wang, X. Zou, L. Zhang, G. Liu, and M. Wan*, “Local cavitation induced vessel wall injury of artery and its potential application in animal model of atherosclerosis,” IEEE International Ultrasonics Symposium, Taipei, Oct. 21-24, 2015.
3.Y. Zong, X. Zou, R. Wang, Y. Feng, M. Wan*, Ultrasound-enhanced extravasation of multifunctional nanodroplets from leaky vessel, IEEE Ultrasonics Symposium (IUS), IEEE International Ultrasonics Symposium, Taipei, Oct. 21-24, 2015
4.Y.J. Zong, J.J. Wan,MX. Wan. (2014) Non-invasive assessment of mechanical and hemodynamic parameters of carotid artery and plaque,International conference on biomedical ultrasound, (Shenzhen)
5.YJ. Zong, N. Zheng, SS Xu, MX. Wan.(2013)Low intensity focused ultrasound triggered local drug delivery from liposome-loaded microbubbles,International Society for Therapeutic Ultrasound Symposium (Shanghai)