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西安电子科技大学生命科学技术学院导师教师师资介绍简介-陈雪利

本站小编 Free考研考试/2021-07-10


基本信息
陈雪利 华山********
博士/硕士生导师
生物医学光子学与分子影像研究室负责人
国家级青年人才项目
陕西省****基金获得者
霍英东青年教师基金获得者
陕西省“特支计划”青年人才项目
西安电子科技大学生命科学技术学院
分子与神经影像教育部工程研究中心

联系方式
通讯地址:陕西省西安市长安区西沣路兴隆段266号 邮编 710126
电子邮箱:xlchen at xidian.edu.cn
办公地点:南校区G楼G401
实验地点:南校区G楼G433/G428
招生信息>>
招聘信息>>

教学任务
医学仪器(本)
计算方法(本)
生物医学光子学(研)
先进医学仪器(研)


个人简介
任职经历
2020.01-至今,西安电子科技大学,华山********
2017.07-至今,西安电子科技大学,生命科学技术学院,教授 (年限破格)
2015.03-2017.03,普渡大学生物医学工程系博士后研究员(CSC项目)
2014.07-2015.02,西安电子科技大学,生命科学技术学院,副教授
2011.07-2014.06,西安电子科技大学,生命科学技术学院,讲师

教育经历
2007.08-2012.03,西安电子科技大学,电子工程学院,模式识别与智能系统博士,导师;高新波教授、田捷教授
2003.08-2007.07,西安电子科技大学,电子工程学院,生物医学工程本科

社会兼职
2021.01-至今,Photonics,客座副主编
2021.01-至今,Frontiers in Oncology,客座副主编
2020.03-至今,Frontiers in Oncology/Pharmacology,客座副主编
2020.01-至今,Artifical Intelligence in Medical Imaging,主编
2019.12-至今,陕西省抗癌协会核医学专委会,委员
2019.10-至今,中国医药生物技术协会造影技术分会,委员
2019.09-至今,科技部重点研发计划政府间/港澳台重点专项通讯评审专家
2019.07-至今,中国光学学会生物医学光子学分会,高级会员(终身)
2019.03-至今,中国生物医学工程学会生物医学光子学分会,高级会员
2018.12-至今,陕西省生物医学工程学会,理事
2018.07-至今,陕西省科技厅社发处科技统筹项目验收组组长/专家
2016.08-至今,美国光学学会,会员
2016.04-至今,自然科学基金委信息学部/医学部/生命学部通讯评审专家
2012.03-至今,美国电气与电子工程师协会,会员
2011.09-至今,国际光学工程学会,会员

期刊审稿
IEEE Trans. Med. Imaging, IEEE Trans. Biomed. Eng., IEEE Photonics J., Opt. Lett.,Opt. Express, Phys. Med. Biol., Biomed. Opt. Express, Eur. Radiol., Opt. Commun., Appl. Opt., J. Biomed. Opt., J. Biomed. Nanotech., Oncogene, Chin. Opt. Lett., etc.

学术成果
截至2020年12月,研究室主持包括国家重点研发计划课题,国家自然科学基金重大科研仪器研制项目课题、面上项目,国家级青年人才项目,陕西省****科学基金、“特支计划”青年人才项目等省部级科研项目18项;已在Nature Communications、Photonics Research、IEEE Transactions on Biomedical Engineering、European Radiology等国际学术期刊发表SCI论文80余篇;获授权美国专利2项,中国发明专利20余项;获陕西省自然科学奖二等奖、教育部科学技术进步奖二等奖、陕西省科学技术奖三等奖、陕西高校科学技术奖一等奖等多项省部/厅局级科技奖励。


研究方向
团队以服务国家和陕西省在医药卫生健康领域的重大战略需求为使命、以重大疾病早期精确检测和中药质量控制为前沿科学问题,围绕早期病变的精确有效定量和中药控制的快检评价,立足信息技术手段,从微观-宏观两个尺度、细胞-动物-人体三个层面研究多尺度定量光学分子成像与检测技术,涵盖成像系统、检测理论、定量与分析方法、成像与检测探针、生物医学基础与转化医学应用。
具体研究方向>>

新闻动态

?2021年研究生招生已结束!现在开始接收2022级研究生,包括推免生和优研计划(招生代码包括083100、085400、077700)。

?[2021-03-31]Congratulations!祝贺团队教师谢晖副教授负责的《现代工科微生物学》入选了陕西省课程思政示范课(省级)!祝贺!!!

?[2020-12-20]Congratulations!祝贺团队教师谢晖副教授荣获第二届全国高校混合式教学创新设计大赛一等奖!祝贺!!!

?[2020-11-16]Congratulations!祝贺研究室负责人陈雪利教授入选国家青年人才项目!祝贺!!!

?[2020-04-17]Congratulations!4月16日,陕西省人民政府发布了《陕西省人民政府关于2019年度陕西省科学技术奖励的决定》,研究室陈雪利教授牵头完成的“面向胃癌早期检测的定量光学分子成像新方法”获得陕西省自然科学奖二等奖!祝贺!!!

?[2020-04-03]Congratulations!近日2020年陕西省科技计划项目公布,研究室负责人陈雪利教授获得陕西省****科学基金项目(陕西省****)资助!祝贺!!!

更多新闻>>




基本信息
陈雪利 华山********
博士/硕士生导师
生物医学光子学与分子影像研究室负责人
国家级青年人才项目
陕西省****基金获得者
霍英东青年教师基金获得者
陕西省“特支计划”青年人才项目
西安电子科技大学生命科学技术学院
分子与神经影像教育部工程研究中心

联系方式
通讯地址:陕西省西安市长安区西沣路兴隆段266号 邮编 710126
电子邮箱:xlchen at xidian.edu.cn
办公地点:南校区G楼G401
实验地点:南校区G楼G433/G428
招生信息>>
招聘信息>>

教学任务
医学仪器(本)
计算方法(本)
生物医学光子学(研)
先进医学仪器(研)


个人简介
任职经历
2020.01-至今,西安电子科技大学,华山********
2017.07-至今,西安电子科技大学,生命科学技术学院,教授 (年限破格)
2015.03-2017.03,普渡大学生物医学工程系博士后研究员(CSC项目)
2014.07-2015.02,西安电子科技大学,生命科学技术学院,副教授
2011.07-2014.06,西安电子科技大学,生命科学技术学院,讲师

教育经历
2007.08-2012.03,西安电子科技大学,电子工程学院,模式识别与智能系统博士,导师;高新波教授、田捷教授
2003.08-2007.07,西安电子科技大学,电子工程学院,生物医学工程本科

社会兼职
2021.01-至今,Photonics,客座副主编
2021.01-至今,Frontiers in Oncology,客座副主编
2020.03-至今,Frontiers in Oncology/Pharmacology,客座副主编
2020.01-至今,Artifical Intelligence in Medical Imaging,主编
2019.12-至今,陕西省抗癌协会核医学专委会,委员
2019.10-至今,中国医药生物技术协会造影技术分会,委员
2019.09-至今,科技部重点研发计划政府间/港澳台重点专项通讯评审专家
2019.07-至今,中国光学学会生物医学光子学分会,高级会员(终身)
2019.03-至今,中国生物医学工程学会生物医学光子学分会,高级会员
2018.12-至今,陕西省生物医学工程学会,理事
2018.07-至今,陕西省科技厅社发处科技统筹项目验收组组长/专家
2016.08-至今,美国光学学会,会员
2016.04-至今,自然科学基金委信息学部/医学部/生命学部通讯评审专家
2012.03-至今,美国电气与电子工程师协会,会员
2011.09-至今,国际光学工程学会,会员

期刊审稿
IEEE Trans. Med. Imaging, IEEE Trans. Biomed. Eng., IEEE Photonics J., Opt. Lett.,Opt. Express, Phys. Med. Biol., Biomed. Opt. Express, Eur. Radiol., Opt. Commun., Appl. Opt., J. Biomed. Opt., J. Biomed. Nanotech., Oncogene, Chin. Opt. Lett., etc.

学术成果
截至2020年12月,研究室主持包括国家重点研发计划课题,国家自然科学基金重大科研仪器研制项目课题、面上项目,国家级青年人才项目,陕西省****科学基金、“特支计划”青年人才项目等省部级科研项目18项;已在Nature Communications、Photonics Research、IEEE Transactions on Biomedical Engineering、European Radiology等国际学术期刊发表SCI论文80余篇;获授权美国专利2项,中国发明专利20余项;获陕西省自然科学奖二等奖、教育部科学技术进步奖二等奖、陕西省科学技术奖三等奖、陕西高校科学技术奖一等奖等多项省部/厅局级科技奖励。


研究方向
团队以服务国家和陕西省在医药卫生健康领域的重大战略需求为使命、以重大疾病早期精确检测和中药质量控制为前沿科学问题,围绕早期病变的精确有效定量和中药控制的快检评价,立足信息技术手段,从微观-宏观两个尺度、细胞-动物-人体三个层面研究多尺度定量光学分子成像与检测技术,涵盖成像系统、检测理论、定量与分析方法、成像与检测探针、生物医学基础与转化医学应用。
具体研究方向>>

新闻动态

?2021年研究生招生已结束!现在开始接收2022级研究生,包括推免生和优研计划(招生代码包括083100、085400、077700)。

?[2021-03-31]Congratulations!祝贺团队教师谢晖副教授负责的《现代工科微生物学》入选了陕西省课程思政示范课(省级)!祝贺!!!

?[2020-12-20]Congratulations!祝贺团队教师谢晖副教授荣获第二届全国高校混合式教学创新设计大赛一等奖!祝贺!!!

?[2020-11-16]Congratulations!祝贺研究室负责人陈雪利教授入选国家青年人才项目!祝贺!!!

?[2020-04-17]Congratulations!4月16日,陕西省人民政府发布了《陕西省人民政府关于2019年度陕西省科学技术奖励的决定》,研究室陈雪利教授牵头完成的“面向胃癌早期检测的定量光学分子成像新方法”获得陕西省自然科学奖二等奖!祝贺!!!

?[2020-04-03]Congratulations!近日2020年陕西省科技计划项目公布,研究室负责人陈雪利教授获得陕西省****科学基金项目(陕西省****)资助!祝贺!!!

更多新闻>>




团队科研方向
围绕国家和陕西省在医药卫生健康领域重大战略需求,以服务国家战略为使命、以解决临床需求为初心、以影像技术发展为指引、以国家重大项目为依托,以重大疾病早期精确检测和中药质量控制为前沿科学问题,围绕早期病变的精确有效定量和中药控制的快检评价,立足信息技术手段,从微观-宏观两个尺度、细胞-动物-人体三个层面研究跨尺度定量光学成像与检测技术,内容涵盖成像系统、成像理论、定量方法、图像分析、分子探针以及生物基础与转化医学应用。具体研究方向包括:
基于拉曼效应的高分辨率动态光谱成像技术
多尺度多模态拉曼-光学投影成像技术
快速高分辨率相干拉曼显微成像技术(基于Raman tag的多色/多通道免标记成像)
基于贝塞尔光束的便携式拉曼光谱成像仪
基于无透镜模式的计算显微成像技术(高通量细胞计数/flow cytometry imaging)
基于荧光效应的高分辨率成像技术
基于共聚焦模式的显微成像技术(内镜、confocal、超分辨)
荧光-拉曼多模态成像技术
基因编码荧光探针及其应用
面向胃癌/食管癌等重大疾病早期检测的定量高灵敏度光学成像技术
胃癌问题特异性的定量光学三维成像理论与方法
定量动态荧光/放射荧光成像技术(软件开发与应用)
高灵敏度微弱光学信号探测技术
多功能多模态分子影像探针
肿瘤乏氧的在体定量可视化技术
智能纳米药物递送系统及在体定量可视化技术
面向转化医学应用的多模态消化内镜技术
内窥光谱成像技术
内窥契伦科夫荧光成像系统及其转化医学应用
基于共聚焦-契伦科夫荧光的多模态内镜系统(国科金重大科研仪器研制项目)







在研与已结题科研项目
研究室先后承担了包括国家重点研发计划课题,国家自然科学基金重大科研仪器研制项目子课题、面上项目(2项)、青年项目(4项),陕西省****科学基金、特支计划青年人才项目、青年科技新星项目、留学人员科技活动择优资助优秀类资助项目、自然科学基金青年项目(结题优秀)等省部级以上科研项目20余项;作为课题骨干参与包括国家自然科学基金委重大科研仪器研制项目、重大项目、科技部973项目等6项。


在研项目(纵向):

陕西省重点研发计划项目,2021ZDLSF04-05、基于“多谱学+药效大数据”的丹参饮质量评估技术体系研究、2021/01-2023/12、100万元。(项目负责人:曾琦)
中央高校基本科研业务费专项基金扶贫专项,QTZX2105、基于贝塞尔光拉曼光谱的金银花药效成分及农药残留检测技术研发、2021/01-2022/12、12万元。(项目负责人:陈雪利、曾琦)
国家级青年人才项目,多尺度定量光学分子成像、2021/01-2023/12、160万元。(项目负责人:陈雪利)
国家自然科学基金青年项目,**、基于大脑信号-在线行为及学习能力的虚拟仿真实验多模态评价研究、2021/01-2023/12、24万元。(项目负责人:谢晖)
国家自然科学基金青年项目,**、基于深度学习和并行蒙特卡洛方法的高精度光学断层重建方法研究、2020/01-2022/12、26.5万元。(项目负责人:任胜寒)
陕西省****科学基金,2020JC-27、多尺度定量光学成像、2020/01-2022/12、30万元。(项目负责人:陈雪利)
国家自然科学基金面上项目,**、基于有限角度稀疏采样的拉曼-光学投影断层成像技术与方法、2019/01-2022/12、57万元。(项目负责人:陈雪利)
国家重点研发计划“精准医学”专项课题,2018YFC**、面向食管癌精准诊疗的高时空分辨率、高灵敏度的多尺度多模态融合分子影像技术研发,2018/07-2020/12、699万元。(课题负责人:陈雪利)
国家重点研发计划“精准医学”专项子课题,2018YFC**、食管癌高特异性、高生物安全性的分子影像探针研制,2018/07-2020/12、608万元。(子课题负责人:陈雪利、徐欣怡,西电经费96.15万元)
霍英东教育基金会第十六届高等学校青年教师基金,161104、内窥式契伦科夫荧光成像的信号增强技术和三维成像方法、2018/03-2021/02、17.4万元。(项目负责人:陈雪利)
陕西省“特支计划”青年人才项目,多尺度多模态生物光学成像技术、2018/01-2020/12、100万元。(项目负责人:陈雪利)
国家自然科学基金重大科研仪器研制项目子课题,**、多模态消化内镜的系统研制及临床应用技术、2017/01-2021/12、220万元。(子课题负责人:陈雪利)


在研项目(横向)

地波远程雷达模型研究,2021/01-2021/06,24.5万元。(项目负责人:陈多芳)


已结题项目:

国家自然科学基金青年项目,**、基于光学分子影像技术的吉马酮对乳腺癌一直活性的在体研究、2018/01-2020/12、20万元。(项目负责人:曾琦)
国家自然科学基金面上项目,**、基于放射荧光-PET-CT多模成像的肿瘤受体三维定量方法、2016/01-2019/12、66.4万。(项目负责人:陈雪利)
国家自然科学基金青年项目,**、内窥式切伦科夫发光断层成像方法研究、2012/01-2014/12、23万元。(项目负责人:陈雪利)
国家自然科学基金青年项目,**、非接触式生物发光成像前向问题研究、2011/01-2013/12、23万元。(项目负责人:陈多芳)
陕西省青年科技新星项目,2018KJXX-018、内窥式放射荧光成像技术及其三维成像方法、2018/01-2020/12、10万。(项目负责人:陈雪利)
陕西省自然科学基金青年项目,2019JQ-201、基于光学投影断层成像及线虫抗菌蛋白表达的抗菌肽备选药物评价研究、2019/01-2020/12、3万元。(项目负责人:谢晖)
陕西省留学人员科技活动择优资助优秀类资助项目,**、基于贝塞尔光束的自发拉曼投影断层成像方法与技术、2018/01-2019/12、5万。(项目负责人:陈雪利)
陕西省自然科学基金面上项目,2018JM7072、基于鸡骨草乙酸乙酯促愈活性的纳米复合贴皮制剂研究、2018/01-2019/12、3万元。(项目负责人:曾琦)
陕西省自然科学基础研究计划青年人才项目,2015JQ6249、内窥式契伦科夫荧光三维成像方法与信号增强技术研究、2015/01-2016/12、2万元 (评价结果为优)。(项目负责人:陈雪利)
中国科学院自动化研究所复杂系统管理与控制国家重点实验室开放课题,**、内窥式契伦科夫荧光成像系统研制、2012/12-2014/12、6万元。(项目负责人:陈雪利)
中央高校基本科研业务费新体制成像项目群类一般项目,NISY6、信号增强型内窥式契伦科夫荧光三维成像方法、2014/05-2016/04、10万元。(项目负责人:陈雪利)
国家自然科学基金联合基金项目,U**、基于多模态影像融合与可视化的复杂先心病手术辅助关键技术研究、2015/01-2018/12、96.8万元。(第四参与人:陈雪利)
国家自然科学基金重大科研仪器设备研制专项(小动物光学多模融合分子影像成像设备),**、光学-PET-CT多模态成像系统研制、2013/01-2017/12、1000万元。(课题骨干:陈雪利;可支配经费200万元)
国家自然科学基金委重点项目,**、核素-切伦科夫多模态显像关键技术研究、2013/01-2017/12、280万元。(第二参与人:陈雪利)
国家自然科学基金重大项目(胃癌恶性生物学行为的分子影像基础研究)子课题,**、多模态分子成像理论、信息融合与在体定量分析、2011/01-2014/12、201万元。(课题骨干:陈雪利;可支配经费50万元)
科技部973项目(多模态分子影像关键科学问题研究) 子课题,2011CB707702、多源影像信息融合与计算平台及多模态成像系统、2011/01-2015/12、93万元。(课题骨干:陈雪利;可支配经费20万元)







Book Chapters

Xueli Chen, Dongmei Chen, Fenglin Liu, Wenxiang Cong, Ge Wang, and Jimin Liang*. Optical-CT Imaging (Chapter 11), Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications (Editors: George C. Kagadis, Nancy L. Ford, Dimitrios Karnabatidis, and George K. Loudos), Taylors & Francis Inc, 11/03/2016
Jie Tian, Jimin Liang, Xueli Chen, and Xiaochao Qu. Molecular Optical Simulation Environment (Chapter 2), Molecular Imaging: Fundamentals and Applications (Editor: Jie Tian), Zhejiang University Press and Springer-Verlag, 15-46, 2012.


Selected Papers

Xueli Chen#,*, Xinyu Wang#, Lin Wang#, Peng Lin, Yonghua Zhan, and Ji-Xin Cheng,“Stimulated Raman scattering signal generation in scattering medium using self-reconstructing Bessel beams,” Photonics Research 2020, 8(6), 929-939. DOI: 10.1364/PRJ.384604. (Raman)
Xueli Chen#,*, Shouping Zhu#, Huiyuan Wang, Cuiping Bao, Defu Yang, Chi Zhang, Peng Lin, Ji-Xin Cheng, Yonghua Zhan, Jimin Liang, and Jie Tian, “Accelerated stimulated Raman projection tomography by sparse reconstruction from sparse-view data,” IEEE Transactions on Biomedical Engineering 2020, 67(5), 1293-1302. DOI: 10.1109/TBME.2019.** (Raman)
Yunpeng Dai#, Guodong Wang#, Duofang Chen, Jipeng Yin, Yonghua Zhan, Yongzhan Nie, Kaichun Wu, Jimin Liang*, and Xueli Chen*, “Intravenous administration-oriented pharmacokinetic model for dynamic bioluminescence imaging,” IEEE Transactions on Biomedical Engineering 2019, 66(3), 843-847. (Quantification)
Xueli Chen#, Chi Zhang#, Peng Lin, Kai-Chih Huang, Jimin Liang, Jie Tian, and Ji-Xin Cheng*, “Volumetric chemical imaging by stimulated Raman projection microscopy and tomography,” Nature Communications 2017, 8, 15117. DOI: 10.1038/ncomms15117 (Raman)
Xueli Chen#, Defu Yang#, Fangfang Sun, Xu Cao, and Jimin Liang*, “Adaptively alternative light-transport-model-based three-dimensional optical imaging for longitudinal and quantitative monitoring of gastric cancer in live animal,” IEEE Transactions on Biomedical Engineering 2016, 63(10), 2095-2107. (Quantification)
Xin Cao#, Xueli Chen#, Fei Kang#, Yonghua Zhan, Xu Cao, Jing Wang*, Jimin Liang*, and Jie Tian*, “Intensity enhanced Cerenkov luminescence imaging using terbium-doped Gd2O2S microparticles,” ACS Applied Materials & Interfaces 2015, 7(22), 11775-11782. (Cerenkov endoscope)
Hao Hu#, Xin Cao#, Fei Kang#, Min Wang, Yenan Lin, Muhan Liu, Shujun Li, Liping Yao, Jie Liang, Jimin Liang, Yongzhan Nie, Xueli Chen*, Jing Wang*, Kaichun Wu*, “Feasibility study of novel endoscopic Cerenkov luminescence imaging system in detecting and quantifying gastrointestinal disease: first human results,” European Radiology 2015, 25(6), 1814-1822. (SCI Citation: 25) (Cerenkov endoscope)
Xueli Chen, Xinbo Gao*, Duofang Chen, Xiaopeng Ma, Xiaohui Zhao, Man Shen, Xiangsi Li, Xiaochao Qu, Jimin Liang, Jorge Ripoll, and Jie Tian*, “3D reconstruction of light flux distribution on arbitrary surfaces from 2D multi-photographic images,” Optics Express 2010, 18(19), 19876-19893. (SCI Citation: 36) (Quantification)

2021YEAR

Xinyu Wang, Lin Wang, Peng Lin, Hui Xie, Xinyi Xu, Qi Zeng, Yonghua Zhan, and Xueli Chen*, "Simulation of stimulated Raman scattering signal generation in scattering tissues excited by Bessel beams," Journal of Innovative Optical Health Sciences 2021, Accepted.
Shenghan Ren#, Yanxia Luo#, Tianyu Yan, Lin Wang, Duofang Chen*, and Xueli Chen, “Machine learning based automatic segmentation of region of interest in dynamic optical imaging,” AIP Advances 2021, 11(1), 015029. DOI: 10.1063/5.**.

2020YEAR

Xin Cao, Jun Zhang, Jianan Yang, Chuixiao Fan, Fengjun Zhao, Wei Zhou, Lin Wang, Guohua Geng, Mingquan Zhou, and Xueli Chen*, “A deep unsupervised clustering-based post-processing framework for high-fidelity Cerenkov luminescence tomography,” Journal of Applied Physics 2020, 128, 193104. DOI: 10.1063/5.**
Xueli Chen#,*, Xinyu Wang#, Lin Wang#, Peng Lin, Yonghua Zhan, and Ji-Xin Cheng,“Stimulated Raman scattering signal generation in scattering medium using self-reconstructing Bessel beams,” Photonics Research 2020, 8(6), 929-939. DOI: 10.1364/PRJ.384604.
Xueli Chen#,*, Shouping Zhu#, Huiyuan Wang, Cuiping Bao, Defu Yang, Chi Zhang, Peng Lin, Ji-Xin Cheng, Yonghua Zhan, Jimin Liang, and Jie Tian, “Accelerated stimulated Raman projection tomography by sparse reconstruction from sparse-view data,” IEEE Transactions on Biomedical Engineering 2020, 67(5), 1293-1302. DOI: 10.1109/TBME.2019.**
Yunpeng Dai#, Duofang Chen#, Guodong Wang, Jipeng Yin, Yonghua Zhan*, Kaichun Wu, Jimin Liang, and Xueli Chen*, “Kinetic modeling and analysis of dynamic bioluminescence imaging of substrates administered by intraperitoneal injection,” Quantitative Imaging in Medicine and Surgery 2020, 10(2), 389-396.
Duofang Chen, Shouping Zhu, Yi Huang, Jimin Liang, and Xueli Chen*, “Removal of random-valued impulse noise from Cerenkov luminescence images,” Medical & Biological Engineering & Computing 2020, 58(1), 131-141.
Nan Wang#, Honghao Cao#, Lin Wang, Feng Ren, Qi Zeng, Xinyi Xu, Jimin Liang, Yonghua Zhan, and Xueli Chen*, “Recent advances in spontaneous Raman spectroscopic imaging: instrumentation and applications,” Current Medicinal Chemistry 2020, 27(36), 6188-6207. DOI: 10.2174/6**1
Ruichan Lv*, Fan Yang, Xue Jiang, Bo Hu, Xianghan Zhang, Xueli Chen, and Jie Tian, “Plasmonic modulated upconversion fluorescence by adjustable distributed gold nanoparticle,” Journal of Luminescence 2020, 220, 116974.
Shenghan Ren, Lin Wang, Qi Zeng, Duofang Chen*, Xueli Chen, and Jimin Liang, “Effective reconstruction of bioluminescence tomography based on GPU-accelerated inverse Monte Carlo method,” AIP Advances 2020, 10, 105329.
Shenghan Ren#, Tianyu Yan#, Lin Wang, Nan Wang, Jimin Liang, Qi Zeng*, and Xueli Chen, “Wide-field Raman spectroscopic imaging with frequency modulation based spatially encoded light illumination,” AIP Advances 2020, 10, 095012.

2019YEAR

Yunpeng Dai#, Guodong Wang#, Duofang Chen, Jipeng Yin, Yonghua Zhan, Yongzhan Nie, Kaichun Wu, Jimin Liang*, and Xueli Chen*, “Intravenous administration-oriented pharmacokinetic model for dynamic bioluminescence imaging,” IEEE Transactions on Biomedical Engineering 2019, 66(3), 843-847.
Ke Li#, Wenhua Zhan#, Yulong Chen, Rajiv Kumar Jha*, and Xueli Chen*, “Docetaxel and doxorubicin codelivery by nanocarriers for synergistic treatment of prostate cancer,” Frontiers in Pharmacology 2019, 10, 1436. doi: 10.3389/fphar.2019.01436
Tianyu Yan#, Qi Zeng#, Lin Wang, Nan Wang, Honghao Cao, Xinyi Xu, and Xueli Chen*, “Harnessing the power of optical microscopic and macroscopic imaging for natural products as cancer therapeutics,” Frontiers in Pharmacology 2019, 10, 1438. DOI: 10.3389/fphar.2019.01438
Lin Wang, Honghao Cao, Xin Cao, Shenghan Ren, Ke Li, Yonghua Zhan, Xueli Chen*, and Xiaowei He*, “Adaptively hybrid 3rd simplified spherical harmonics with diffusion equation based multispectral Cerenkov luminescence tomography,” IEEE Access 2019, 7, 160779. DOI: 10.1109/ACCESS.2019.**
Hui Xie#, Huiyuan Wang#, Lin Wang, Nan Wang, Jimin Liang, Yonghua Zhan, and Xueli Chen*, “Comparative studies of total-variation-regularized sparse reconstruction algorithms in projection tomography,” AIP Advances 2019, 9, 085122. Aug. 23, 2019. DOI: 10.1063/1.**
Nan Wang#, Duofang Chen#, Dan Chen, Cuiping Bao, Jimin Liang, Xueli Chen*, and Shouping Zhu*, “Feasibility study of limited-angle reconstruction for in vivo optical projection tomography based on novel sample fixation,” IEEE Access 2019, 7(1), 87681-87691.
Xinyi Xu#, Hanrui Li#, Ke Li, Qi Zeng, Yin Liu, Yun Zeng, Dan Chen, Jimin Liang, Xueli Chen*, and Yonghua Zhan*, “A photo-triggered conjugation approach for attaching RGD ligands to biodegradable mesoporous silica nanoparticles for the tumor fluorescent imaging,” Nanomedcine-Nanotechnology, Biology, and Medicine 2019, 19(4), 136-144.
Xiaoxia Cai, Qingxia Zhu, Yun Zeng, Qi Zeng, Xueli Chen, and Yonghua Zhan*, “Manganese oxide nanoparticles as MRI contrast agents in tumor multimodal imaging and therapy,” Internal Journal of Nanomedicine 2019, 14, 8321-8344.
Hanrui Li#, Ke Li#, Qi Zeng, Yun Zeng, Dan Chen, Liaojun Pang, Xueli Chen, and Yonghua Zhan*, “Novel vinyl-modified RGD conjugated silica nanoparticles based on photo click chemistry for in vivo prostate cancer targets fluorescence imaging,” RSC Advances 2019, 9, 25318.
Qi Zeng, Hongjin Song, Xinyi Xu, Wenjie Mao, Hui Xie, Jimin Liang, Xueli Chen, Dan Chen, and Yonghua Zhan*, “Health effects of kiwi wine on rats: an untargeted metabolic fingerprint study based on GC-MS/TOF,” RSC Advances 2019, 9(24), 13797-13807.

2018YEAR

Yunpeng Dai#, Guodong Wang#, Duofang Chen, Jipeng Yin, Yonghua Zhan, Yongzhan Nie, Kaichun Wu, Jimin Liang*, and Xueli Chen*,“Intravenous administration-oriented pharmacokinetic model for dynamic bioluminescence imaging,” IEEE Transactions on Biomedical Engineering 2018, In press. DOI:10.1109/TBME.2018.**
Yun Zeng#, Jingwen Ma#, Yonghua Zhan, Xinyi Xu, Qi Zeng, Jimin Liang*, and Xueli Chen*,“Hypoxia-activated prodrugs and redox-responsive nanocarriers,” International Journal of Nanomedicine 2018, 12(9-10), 542-546.
Lin Wang#, Xin Cao#,*, Xu Cao, Fei Kang, Yonghua Zhan, Xiaowei He, Jing Wang*, and Xueli Chen*,“Feasibility study of radioluminescence film imaging: an optical way to detect medical radionuclides,” Optoelectronics and Advanced Materials-Rapid Communications 2018, 12(9-10), 542-546.
Defu Yang, Chenggang Yan*, Lei Yang, Dongliang Peng, and Xueli Chen*,“An alternative reconstruction framework with optimal permission source region for bioluminescence tomography,” Optical Communications 2018, 427(11), 112-122.
Defu Yang, Lin Wang, Dongmei Chen, Chenggang Yan, Xiaowei He, Jimin Liang, and Xueli Chen*, “Filtered maximum likelihood expectation maximization based global reconstruction for bioluminescence tomography,” Medical & Biological Engineering & Computing 2018, Online. DOI:10.1007/s11517-018-1842-z
Hanrui Li#, Ke Li#, Yunpeng Dai, Xinyi Xu, Xu Cao, Qi Zeng, Huyulong He, Liaojun Pang, Jimin Liang, Xueli Chen*, and Yonghua Zhan*,“In vivo near infrared fluorescence imaging and dynamic quantification of pancreatic metastatic tumors using folic acid conjugated biodegradable mesoporous silica nanoparticles,” Nanomedicine-Nanotechnology Biology and Medicine 2018, 14(6),1867-1877.
Lin Wang, Xin Cao, Qingyun Ren, Xueli Chen*, Xiaowei He*,“Hybrid model based unified scheme for endoscopic Cerenkov and radio-luminescence tomography: simulation demonstration,” Journal of Applied Physics 2018, 123(18), 184701.
Yunpeng Dai#, Xueli Chen#,*, Jipeng Yin, Guodong Wang, Bo Wang, Yonghua Zhan*, Yongzhan Nie, Kaichun Wu, and Jimin Liang*, “Investigation of the influence of sampling schemes on quantitative dynamic fluorescence imaging,” Biomedical Optics Express 2018, 9(4), 1859-1870.
Lin Wang, Shenghan Ren, andXueli Chen*, “Comparative evaluations of the Monte Carlo-based light propagation simulation package for optical imaging,”Journal ofInnovative Optical Health Sciences2018, 11(1), **.
Hui Xie, Yonghua Zhan, Xueli Chen, Qi Zeng, Dan Chen, and Jimin Liang, “Brevinin-2 drug family-new applied peptide candidates against methicillin-resistant Staphylococcus arreus and their effects on Lys-7 expression of innate immune pathwary DAF-2/DAF-16 in Caenorhabditis elegans,” Applied Science 2018, 8, 2627.
Xu Cao, Yuzhu Gong, Shouping Zhu, Xuanxuan Zhang, Xueli Chen, and Yonghua Zhan*,“In vivo optical imaging with Y2O2S:Eu:Mg:Ti persistent luminescent nanoparticles,” Optoelectroincs and Advanced Materials-Rapid Communications 2018, 12(7-8), 467-471.
Xuanxuan Zhang, Shouping Zhu, Yang Li, Yonghua Zhan, Xueli Chen, Fei Kang, Jing Wang, and Xu Cao*,“Gamma rays excited radioluminescence tomographic imaging,” Biomedical Engineering Online 2018, 17, 45.

2017YEAR

Xueli Chen#, Chi Zhang#, Peng Lin, Kaichih Huang, Jimin Liang, Jie Tian, and Ji-Xin Cheng*, “Volumetric chemical imaging by stimulated Raman projection microscopy and tomography,” Nature Communications 2017, 8, 15117. DOI: 10.1038/ncomms15117
Yonghua Zhan#, Xu Cao#, Xin Cao, Yingchao Li, Jie Tian, Jimin Liang*, and Xueli Chen*, “Silica Cross-Linked Micellar Core-Shell Nanoparticles Encapsulating IR-780 with Strong Bright and Good Biocompatibility for Optical Imaging In Vivo,” Journal of Biomedical Nanotechnology 2017, 13(2), 144-154. DOI:10.1166/jbn.2016.2332
Yonghua Zhan#, Wenhua Zhan#, Hanrui Li, Xinyi Xu, Xu Cao, Shouping Zhu, Jimin Liang*, and Xueli Chen*, “In vivo dual-modality fluorescence and magnetic resonance imaging-guided lymph node mapping with good biocompatibility manganese oxide nanoparticles,” Molecules 2017, 22(12), 2208. DOI: 10.3390/molecules**
Defu Yang, Xueli Chen*, Chunhui Zhang, Lu Wang, Fanzhen Meng, Qingguo Xie, and Jimin Liang, “Cerenkov luminescence imaging guided selective-reconstruction for a flexible dual-head PET,” Journal of Instruments 2017, 12(4), P04005. DOI: 10.1088/1748-0221/12/04/P04005
Lin Wang#, Yonghua Zhan#, Defu Yang, and Xueli Chen*, “Specific modeling of light propagation in live body with coupled SP3-radiosity-diffusion equation,” Journal of Medical Imaging and Health Informatics 2017, 7(4), 820-832.DOI:10.1166/jmihi.2017.2088
Xin Cao#, Yonghua Zhan#, Xu Cao, Jimin Liang, and Xueli Chen*, “Harnessing the power of Cerenkov luminescence imaging for gastroenterology: Cerenkov luminescence endoscopy,” Current Medical Imaging Reviews 2017, 13(1), 50-57. DOI: 10.2174/**66**4
Yonghua Zhan#, Xu Cao#, Yingchao Li, Xueli Chen*, and Xiaofeng Huang*, “Synthesis and biological evaluation of a novel apogossypolone derivative,” Letters in Drug Design & Discovery 2017, 14(1), 96-101. DOI: 10.2174/**66**5
Fanzhen Meng, Xu Cao, Xuezhou Cao, Jianxun Wang, Liang Li, Xueli Chen, Shouping Zhu*, and Jimin Liang*, “Influence of rotation increments on imaging performance for a rotatory dual-head PET system,” Biomed Research International 2017, **.
Fanzhen Meng, Shouping Zhu*, Liang Li, Jianxu Wang, Xuezhou Cao, Xu Cao, Xueli Chen, and Jimin Liang,“Performance evaluation of a rotatory dual-head PET system with 90o increments for small animal imaging,” Journal ofInstrumentation 2017, 12(9), P09001.

2016YEAR

Xueli Chen#, Defu Yang#, Fangfang Sun, Xu Cao, and Jimin Liang*, “Adaptively alternative light-transport-model-based three-dimensional optical imaging for longitudinal and quantitative monitoring of gastric cancer in live animal,” IEEE Transactions on Biomedical Engineering 2016, 63(10), 2095-2107. DOI: 10.1109/TBME.2015.**.
Yunpeng Dai, Xueli Chen*, Jipeng Yin, Xiaoyu Kang, Guodong Wang, Xianghan Zhang, Yongzhan Nie, Kaichun Wu, and Jimin Liang*, “Investigation of injection dose and camera integration time on quantifying pharmacokinetics of a Cy5.5-GX1 probe with dynamic fluorescence imaging in vivo,” Journal of Biomedical Optics 2016, 21(8), 086001. DOI: 10.1117/1.JBO.21.8.086001.
Yunpeng Dai, Jipeng Yin, Yu Huang, Xueli Chen*, Guodong Wang, Yajun Liu, Xianghan Zhang, Yongzhan Nie, Kaichun Wu, and Jimin Liang*, “In vivo quantifying molecular specificity of Cy5.5-labeled cyclic 9-mer peptide probe with dynamic fluorescence imaging,” Biomedical Optics Express 2016, 7(3), 1149-1159. DOI:10.1364/BOE.7.001149
Yonghua Zhan#, Xu Cao#, Xin Cao, Fei Kang, Jing Wang, Jimin Liang, Zhimin Li*, and Xueli Chen*, “Simultaneous multimodality molecular imaging with neodymium-doped Y3Al3O12 nanoparticles,” Optoelectronics and Advanced Materials-Rapid Communications 2016, 10(9-10), 685-688.
Shenghan Ren, Haihong Hu, Gen Li, Xu Cao, Shouping Zhu, Xueli Chen, and Jimin Liang*, “Multi-atlas registration and adaptive hexahedral voxel discretization for fast bioluminescence tomography,” Biomedical Optics Express 2016, 7(3), 1549-1560.
Shenghan Ren, Xueli Chen, Xu Cao, Shouping Zhu, and Jimin Liang*, “GPU accelerated simplified harmonic spherical approximation equations for three-dimensional optical imaging,” Chinese Optics Letters 2016, 14(7), 071701.
Fengjun Zhao, Jimin Liang*, Xueli Chen, Junting Liu, Dongmei Chen, Xiang Yang, and Jie Tian, “Quantitative analysis of vascular parameters for micro-CT imaging of vascular networks with multi-resolution,” Medical & Biological Engineering & Computing 2016, 54(2-3), 511-524.
Xu Cao, Yang Li, Yonghua Zhan, Xueli Chen, Fei Kang, Jing Wang, and Jimin Liang*, “Removing noises induced by Gamma radiation in Cerenkov luminescence imaging using a temporal median filter,” Biomed Research International 2016, **.

2015YEAR

Xueli Chen*, Fangfang Sun, Defu Yang, and Jimin Liang, “Coupled 3rd order simplified spherical harmonics and diffusion equation based fluorescence tomographic imaging of liver cancer,” Journal of Biomedical Optics 2015, 20(9), 090502. DOI: 10.1117/1.JBO.20.9.090502
Xueli Chen*, Fangfang Sun, Defu Yang, Shenghan Ren, Qian Zhang, and Jimin Liang*, “Hybrid simplified spherical harmonics with diffusion equation for fluorescent light propagation in tissues,” Physics in Medicine and Biology 2015, 60(16), 6305-6322.
Xin Cao#, Xueli Chen#, Fei Kang#, Yonghua Zhan, Xu Cao, Jing Wang*, Jimin Liang*, and Jie Tian*, “Intensity enhanced Cerenkov luminescence imaging using terbium doped Gd2O2S microparticles,” ACS Applied Materials & Interfaces 2015, 7(22), 11775-11782. DOI: 10.1021/acsami.5b00432. Jun 10, 2015
Xin Cao, Xueli Chen*, Fei Kang, Xu Cao, Yonghua Zhan, Jing Wang, Kaichun Wu, and Jimin Liang*, “Sensitivity improvement of Cerenkov luminescence endoscope with terbium doped Gd22S nanoparticles,” Applied Physics Letters 2015, 106(21), 213702. DOI: 10.1063/1.**
Hao Hu#, Xin Cao#, Fei Kang#, Min Wang, Yenan Lin, Muhan Liu, Shujun Li, Liping Yao, Jie Liang, Jimin Liang, Yongzhan Nie, Xueli Chen*, Jing Wang*, Kaichun Wu*, “Feasibility study of novel endoscopic Cerenkov luminescence imaging system in detecting and quantifying gastrointestinal disease: first human results,” European Radiology 2015, 25(6), 1814-1822. DOI: 10.1007/s00330-014-3574-2
Defu Yang, Xueli Chen*, Jing Wang, Jimin Liang, and Jie Tian, “Performance investigation of SP3 and diffusion approximation for three-dimensional optical imaging,” Medical & Biological Engineering & Computing 2015, 53(9), 805-814. DOI: 10.1007/s11517-015-1293-8
Chuihui Zhang, Xueli Chen, Shouping Zhu, Lu Wan, Qingguo Xie, and Jimin Liang*, “Performance evaluation of a 900-rotating dual-head small animal PET system,” Physics in Medicine and Biology 2015, 60(15), 5873-5890.
Fengjun Zhao, Jimin Liang*, Dongmei Chen, Chuan Wang, Xiang Yang, Xueli Chen, and Feng Cao, “Automatic segmentation method for bone and blood vessel in murine hindlimb,” Medical Physics 2015, 42(7), 4043-4054.

2014YEAR and Before

Xueli Chen*, Defu Yang, Qitan Zhang, and Jimin Liang*, “L1/2 regularization based numerical method for effective reconstruction of bioluminescence tomography,” Journal of Applied Physics 2014, 115(18), 184702. May 14, 2014
Xueli Chen*, Qitan Zhang, Defu Yang, and Jimin Liang*, “Hybrid radiosity-SP3 equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions,” Journal of Applied Physics 2014, 115(2), 024702. Jan 14, 2014
Xin Cao#, Xueli Chen#, Fei Kang#, Yenan Lin, Muhan Liu, Hao Hu, Yongzhan Nie, Kaichun Wu, Jing Wang*, Jimin Liang*, and Jie Tian*, “Performance evaluation of endoscopic Cerenkov luminescence imaging system: in vitro and pseudotumor studies,” Biomedical Optics Express 2014, 5(10), 3660-3670.
Xueli Chen*, Jimin Liang, Xin Cao, Defu Yang, Dongmei Chen, Jorge Ripoll, and Jie Tian*, “Feasibility study of endoscopic X-ray luminescence computed tomography: simulation demonstration and phantom application,” Journal of Applied Physics 2013, 114(8), 084701. Aug 28, 2013
Defu Yang#, Xueli Chen#, Zhen Peng, Xiaorui Wang, Jorge Ripoll, Jing Wang, and Jimin Liang*, “Light transport in turbid media with non-scattering, low-scattering and high absorption heterogeneities based hybrid simplified spherical harmonics with radiosity model,” Biomedical Optics Express 2013, 4(10), 2209-2223.
Xueli Chen#, Defu Yang#, Xiaochao Qu, Hao Hu, Jimin Liang*, Xinbo Gao, and Jie Tian*, “Comparisons of hybrid radiosity-diffusion model and diffusion equation for bioluminescence tomography in cavity cancer detection,” Journal of Biomedical Optics 2012, 17(6), 066015.
Zhenhua Hu#, Xueli Chen#, Jimin Liang*, Xiaochao Qu, Duofang Chen, Weidong Yang, Jing Wang, Feng Cao, and Jie Tian*, “Single photon emission computed tomography- guided Cerenkov luminescence tomography,” Journal of Applied Physics 2012, 112(2), 024703.
Qitan Zhang#, Xueli Chen#, Xiaochao Qu, Jimin Liang*, and Jie Tian*, “Comparative studies of lp-regularization-based reconstruction algorithms for bioluminescence tomography,” Biomedical Optics Express 2012, 3(11), 2816-2836.
Xueli Chen, Jimin Liang*, Xiaochao Qu, Yanbin Hou, Shouping Zhu, Duofang Chen, Xinbo Gao, and Jie Tian*, “Mapping of bioluminescent images onto CT volume surface for dual-modality BLT and CT imaging,” Journal of X-ray Science and Technology 2012, 20(1), 31-44.
Xueli Chen, Jimin Liang*, Heng Zhao, Xiaochao Qu, Duofang Chen, Qitan Zhang, Xinbo Gao, and Jie Tain*, “Modeling and reconstruction of optical tomography for endoscopic applications: simulation demonstration,” Applied Physics Letters 2011, 99(7), 073702.
Xueli Chen, Xinbo Gao*, Duofang Chen, Xiaopeng Ma, Xiaohui Zhao, Man Shen, Xiangsi Li, Xiaochao Qu, Jimin Liang, Jorge Ripoll, and Jie Tian*, “3D reconstruction of light flux distribution on arbitrary surfaces from 2D multi-photographic images,” Optics Express 2010, 18(19), 19876-19893.
Xueli Chen, Xinbo Gao*, Xiaochao Qu, Duofang Chen, Xiaopeng Ma, Jimin Liang, and Jie Tian*, “Generalized free-space diffuse photon transport model based on the influence analysis of camera lens,” Applied Optics 2010, 49(29), 5654-5664.
Xueli Chen, Xinbo Gao*, Xiaochao Qu, Jimin Liang, Lin Wang, Da’an Yang, Anikitos Garofalakis, Jorge Ripoll, and Jie Tian*, “A study of photon propagation in free-space based on hybrid radiosity-radiance theorem,” Optics Express 2009, 17(18), 16266- 16280.


Conference Presentations

Nan Wang, Feng Ren, Xu Nie, Xinyu Xu, Qi Zeng, Yonghua Zhan, Shouping Zhu, and Xueli Chen*, “Drug detection in different pharmaceutical dosage forms with Bessel beam-based Raman spectroscopy,” SPIE Photonics West 2021, March 6-11, 2021, San Francisco, CA, USA. Oral Presentation.
Feng Ren, Haoyu Wang, Nan Wang, Yichao Liu, Yonghua Zhan, and Xueli Chen*, “Feasibility study of Bessel beam based Raman spectroscopy,” SPIE Photonics West 2020, February 1-6, 2020, San Francisco, CA, USA. Oral presentation.
Duofang Chen, Xixin Luo, Zhaohui Wang, Jimin Liang, and Xueli Chen*, “Label-free cell analysis and classification with lens-less computational imaging,” SPIE Photonics West 2020, February 1-6, 2020, San Francisco, CA, USA. Oral presentation.
Xixin Luo, Duofang Chen, Yonghua Zhan, Jimin Liang, and Xueli Chen*, “Raman tomography with frequency modulated excitation and spatially coded detection,” SPIE Photonics West 2019, February 2-7, 2019, San Francisco, CA, USA. Oral presentation. Appear in the Label-free Biomedical Imaging and Sensing (LBIS) 2019, Proc. of SPIE 2019, 10890, **. DOI: 10.1117/12.**
Tianyu Yan, Feiyang Lu, Duofang Chen, Yonghua Zhan, Jimin Liang, and Xueli Chen*, “Raman spectroscopic imaging with frequency modulation based spatially encoded light,” SPIE Photonics West 2019, February 2-7, 2019, San Francisco, CA, USA. Oral presentation. Appear in the Label-free Biomedical Imaging and Sensing (LBIS) 2019, Proc. of SPIE 2019, 10890, **. DOI: 10.1117/12.**
Xinyu Wang, Yonghua Zhan, Jimin Liang, and Xueli Chen*, “Simulation of the stimulated Raman scattering signal generation in scattering media excited by Bessel beams,” SPIE Photonics West 2019, February 2-7, 2019, San Francisco, CA, USA. Oral presentation. Appear in the Label-free Biomedical Imaging and Sensing (LBIS) 2019, Proc. of SPIE 2019, 10890, 108900R. DOI: 10.1117/12.**
Huiyuan Wang, Cuiping Bao, Shouping Zhu, Yonghua Zhan, Jimin Liang, and Xueli Chen*, “Fast stimulated Raman projection tomography with iterative reconstruction from sparse projections,” SPIE Photonics West 2019, February 2-7, 2019, San Francisco, CA, USA. Oral presentation. Appear in the Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVI 2019, Proc. of SPIE 2019, 10883, 108830E. DOI: 10.1117/12.**
Nan Wang, Duofang Chen, Cuiping Bao, Jimin Liang, Xueli Chen, and Shouping Zhu*, “Feasibility study of limited-angle reconstruction based in vivo optical projection tomography,” SPIE Photonics West 2019, February 2-7, 2019, San Francisco, CA, USA. Oral presentation. Appear in the Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVI 2019, Proc. of SPIE 2019, 10883, 108830S. DOI: 10.1117/12.**
Yonghua Zhan*, Xu Cao, Xueli Chen, and Jimin Liang, “Radiolabeled antibody- conjugated manganese oxide nanoparticles as a platform for tumor vasculature target PET and MRI,” 2018 SNNMI Mid-Winter Symposium and ACNM Annual Meeting, January 25-27, 2018, Orlando, FL, USA. Oral presentation.
Xueli Chen*, Xin Cao, Fei Kang, Muhan Liu, Yonghua Zhan, Jing Wang, Kaichun Wu, Jimin Liang, and Jie Tian, “Monitoring ApoG2 therapy in gastric and colorectal cancer with endoscopic Cerenkov luminescence imaging and positron emission tomography,” Proceeding of the 2014 World Molecular Imaging Congress, Seoul, Korea, Sep. 17-20. Oral presentation.
Xueli Chen*, Defu Yang, Xin Cao, and Jimin Liang, “Specific modeling of light transport in biological tissues for Cerenkov luminescence tomography,” 2014 Annual Meeting of Society of Nuclear Medicine and Molecular Imaging, June 7-11, 2014, St. Louis, USA. Oral presentation; included in The Journal of Nuclear Medicine 2014, 55(Supp1), 264.
Xin Cao, Hao Hu, Yenan Lin, Xiaowei Ma, Xueli Chen, Jing Wang, Kaichun Wu, and Jimin Liang*, “A feasibility study of an endoscopic Cerenkov luminescence imaging system,” 2013 Annual Meeting of Society of Nuclear Medicine and Molecular Imaging, June 8-12, 2013, Vancouver, BC, Canada. Oral presentation; included in The Journal of Nuclear Medicine 2013, 52(Supp2), 599.
Yunpeng Dai, Xueli Chen*, and Jimin Liang, “In vivo quantifying dose-dependent pharmacokinetics of Cy5.5-labeled cyclic 9-mer peptide probe with dynamic fluorescence imaging,” Proceeding of the 2016 World Molecular Imaging Congress, New York USA, Sep. 7-10. Poster presentation. (Winner of student travel award)
Xin Cao, Yenan Lin, Fei Kang, Xueli Chen*, Jing Wang, Kaichun Wu, Jimin Liang, and Jie Tian, “A novel imaging algorithm for endoscopic Cerenkov luminescence tomography,” Proceeding of the 2014 World Molecular Imaging Congress, Seoul, Korea, Sep. 17-20. Poster presentation. (Winner of student travel award)
Defu Yang, Xueli Chen*, Fanzhen Meng, Jimin Liang, and Jie Tian, “Image reconstruction for a dual-head PET guided by the Cerenkov luminescence imaging,” Proceeding of the 2014 World Molecular Imaging Congress, Seoul, Korea, Sep. 17-20. Poster presentation. (Winner of student travel award)
Defu Yang, Xueli Chen, Xiaochao Qu, Jimin Liang, and Jie Tian*, “Light transport in turbid media based on simplified spherical harmonics coupled with radiosity theory,” Proceeding of the 2012 World Molecular Imaging Congress, Dublin, Ireland, Sep. 5-8. Poster presentation. (Winner of student travel award)
Xueli Chen, Jimin Liang, Xiaochao Qu, Duofang Chen, Defu Yang, and Jie Tian*, “Endoscopic bioluminescence tomography: A new solution to deep bioluminescent probe imaging,” Proceeding of the 2011 World Molecular Imaging Congress, San Diego, USA, Sep. 7-10. Poster presentation. (Winner of student travel award)

国内会议邀请报告

2020年12月28日,徐欣怡、陈雪利,中国生物物理学会材料生物学与智能诊疗计数分会青年****年会暨2020年生物医学材料与技术交叉青年论坛生物医学诊疗材料与技术分论坛邀请报告(基于“基因密码子扩展”的纳米抗体探针用于肿瘤成像研究),浙江宁波。
2020年12月27日,陈雪利,中国生物物理学会材料生物学与智能诊疗计数分会青年****年会暨2020年生物医学材料与技术交叉青年论坛生物医学影像材料与技术分论坛邀请报告(定量光学分子成像技术:理论、方法与应用),浙江宁波。
2020年12月7日,陈雪利,第四届光学青年科学家论坛:光学成像专题邀请分会口头报告(深度网络辅助的个位数投影断层成像方法),浙江宁波。
2020年12月6日,周王婷、陈雪利,第四届光学青年科学家论坛:生物光子学专题邀请分会口头报告(光声/OCT引导动脉粥样硬化斑块的脂质选择性消融术),浙江宁波
2020年11月30日,陈雪利,华南师范大学生物光子学研究院邀请学术报告(多尺度定量光学分子成像),广东广州。
2020年11月2日,陈雪利,慈溪医工所邀请学术报告(光学分子影像技术的临床应用探索:从契伦科夫荧光内窥镜到多模态跨尺度内镜),浙江慈溪。
2020年8月7日,陈雪利,卓立汉光名师讲堂邀请报告(贝塞尔光束在拉曼光谱成像技术中的应用),线上会议。
2020年6月2日,陈雪利、曾琦、谢晖,商洛学院生物医药与食品工程学院学术报告(天然活性物质的发现与功能评价),陕西商洛。
2020年1月7日,陈雪利、曾琦,浙江宏胜饮料集团有限公司学术报告(基于拉曼光谱的物质成分快速检测技术),浙江杭州。
2019年12月21日,陈雪利,第十一届西部光子学会议分会场主持人,主持专题:微纳光子学、信息光子学技术与应用、空天光学与光电工程,陕西西安。
2019年10月26-27日,陈雪利,Nature转化影像学会议(Nature BME与ISMI 2019共同主办)青年****奖报告(Wide-field, high-throughput imaging of pathological slides with lens-less computational imaging),广东珠海。
2019年10月23-25日,陈雪利,第二届海峡两岸生物医学前沿交叉学术研讨会邀请报告(Quantitative biophotonic imaging: a platform for gastric cancer detection),台湾新竹。
2019年8月19-21日,陈雪利,中国生物医学工程学会大连青年论坛邀请报告(基于贝塞尔光束的深度扩展型受激拉曼显微成像方法),辽宁大连。
2019年8月9-11日,陈雪利,中国光学学会学术大会生物医学光子学专题邀请报告(基于贝塞尔光的散射介质中受激拉曼显微成像),安徽合肥。
2019年7月5-7日,陈雪利,第一届分子与神经影像、智能影像与质量安全专题学术会议邀请报告(光学分子影像及其在胃肠道临床检测中的转化应用探索),江苏镇江。
2018年11月21日,陈雪利,西安医学院基础与转化医学研究所邀请学术报告(光学分子成像及其转化医学应用),陕西西安。
2018年10月27-28日,陈雪利,第二届珠海分子影像国际论坛特邀报告(Quantitative Biophotonics Imaging: a platform for gastric cancer detection),广东珠海。
2018年6月2日,陈雪利,首届北京航空航天大学医用光子学国际研讨会分会主席与邀请报告(多尺度生物光学成像),北京。
2017年8月27日,陈雪利,第二届生物医学成像新技术新方法青年论坛特邀报告(基于受激拉曼投影成像的三维显微容积成像方法),西安曲江。
2019年8月22-25日,徐欣怡、陈雪利,中国生物材料大会暨中国生物医学工程学会生物材料分会年会墙报快速演讲(A photo-triggered conjugation approach for attaching RGD ligands to biodegradable mesoporous silica nanoparticles for the tumor fluorescent imaging),辽宁大连。
2019年8月19-21日,徐欣怡、陈雪利,中国生物医学工程学会大连青年论坛邀请报告(新型靶向分子荧光探针成像研究),辽宁大连。
2020年11月29日,王楠、任枫、陈雪利,第二届全国光子技术论坛口头报告(基于贝塞尔光拉曼光谱仪的散射介质中药物检测),广东广州。
2020年11月29日,闫天宇、陈雪利,第二届全国光子技术论坛口头报告(一种用于胃癌早期检测的多模态消化内镜),广东广州。
2019年12月21日,王鑫宇、陈雪利,第十一届西部光子学学术会议口头报告(深层生物组织中受激拉曼显微成像仿真的设计与实现),陕西西安。
2019年12月21日,范大玮、陈雪利,第十一届西部光子学学术会议口头报告(基于硅光电倍增管的共聚焦激光扫描显微镜的设计与实现),陕西西安。
2019年8月17-19日,王汇元、陈雪利,第十二届光学与光电子国际学术会议口头报告(Comparative studies of TV-regularized sparse reconstruction algorithms in projection tomography),陕西西安。
2018年12月7-10日,王楠、陈雪利,全国第二届生物医学拉曼光谱学术会议口头报告(Fast stimulated Raman projection tomography by sparse reconstruction from few-views data),上海。
2018年11月5-9日,王楠、陈雪利,第八届光学方法高级研讨会口头报告(Fast stimulated Raman projection tomography by sparse reconstruction from few-views data),广东深圳。
2018年11月5-9日,曹鸿昊、陈雪利,第八届光学方法高级研讨会口头报告(Performance improvement of Cerenkov luminescence endoscope by optimizing system structure),广东深圳。
2018年11月5-9日,闫天宇、陈雪利,第八届光学方法高级研讨会口头报告(Raman spectroscopic imaging with frequency modulation based spatially encoded light),广东深圳。
2018年11月5-7日,蔡晓霞、詹勇华、陈雪利,生物医学材料国际合作论坛暨第十届全国低场核磁共振技术与应用研讨会口头报告(Radiolabeled, Antibody-Conjugated Manganese Oxide Nanoparticles for Tumor Vasculature Targeted Positron Emission Tomography and Magnetic Resonance Imaging),浙江宁波。
2018年10月27-28日,李函蕊(博一)、蔡晓霞(研二)获第二届珠海分子影像国际论坛“青年学子奖”,曹鸿昊(研二)获第二届珠海分子影像国际论坛“最佳摘要奖”。


同行评价
转化应用:与临床医院合作开展的胃肠道肿瘤内窥契伦科夫荧光成像临床试验相关工作(European Radiology 2015, 25(6), 1814-1822)受到了成像领域著名专家和临床医生的高度评价。国际同行(契伦科夫荧光成像概念提出者之一的A.E. Spinelli,法国马赛大学医院核医学科医生D. Ta?e,契伦科夫荧光成像领域著名专家、美国纽约纪念斯隆凯特琳癌症中心的J. Grimm,以及英国国王健康联盟癌症中心主任、英国癌症研究协会高级临床顾问、伦敦国王学院乳腺癌专家A. Purushotham)的高度评价,称我们首次获得了病人的内窥式契伦科夫荧光成像结果(引文见Biomed. Opt. Express 2015, 6(6): 2168-2180),这在胃肠道恶性肿瘤的检测中具有潜在应用价值(引文见Eur. J. Nucl. Med. Mol. Imaging 2015, 42(7): 1144-1155),是首次的临床研究(引文见J. Nucl. Med. 2016, 57(11): 1661-1666),是迄今为止契伦科夫荧光成像技术的三个临床试验之一(引文见J. Nucl. Med. 2017, 58(6), 891-898)。
成像系统:高分辨率定量三维受激拉曼显微成像技术(Nature Communications 2017, 8, 15117)被哥伦比亚大学Wei Min教授在国际顶级期刊上撰文称候选人研发的快速三维受激拉曼显微成像技术为深层组织、大体积活体成像提供了希望(Nat. Commun. 2018,9:29995)、与样本透明化相结合可实现快速三维成像(PNAS 2019,116: 6608);卡迪夫大学P. Borri教授在分析化学顶级期刊上撰文称实现了快速三维容积成像(Anal. Chem. 2018,90:3775)。内窥契伦科夫荧光成像系统(Biomedical Optics Express 2014, 5, 3660)被国际同行、达特茅斯大学B. Pogue教授评价称通过采用内窥的方式探测人体内部器官是可行的(Biomed. Opt. Express 2015, 6, 3053)。
成像理论:关于自由空间光传输模型的研究结果(Optics Express 2010, 18(19), 19876-19893)得到光学三维成像领域国际著名专家(时任Opt. Express 副主编) Hamid Dehghani的肯定评价,称该工作扩展了自由空间光传输理论建模问题,为透镜系统提供了概念上的准确描述,同时可准确地提供体表三维能量的定性分布,对生物发光断层成像是非常有用的(引文见J. Opt. Soc. Am. A 2013, 30(12): 2572-2584)。关于生物组织光传输混合模型的研究结果(Journal of Biomedical Optics 2015, 20(9), 090502)得到国家同行、印度理工学院坎普尔分院N. Naik博士的肯定评价,在医学影像领域顶级期刊IEEE Transactions on Medical Imaging上撰文称该模型实现了计算效率和建模精度之间的平衡(IEEE Trans. Med. Imaging 2017, 36: 2308)。针对胃癌肿瘤特性的空腔结构处理模型(Applied Optics 2013, 52(3), 400-408)被意大利博洛尼亚大学先进信息与通信电子系统研究中心的S. Placati 博士评价为我们的方法相比于简单扩散近似模型显著改进了精度,相比于辐射传输方程或蒙特卡洛方法显著改进了计算效率(IEEE Trans. Biomed. Eng. 2016, 63:1874)。
成像方法:基于L0正则化的三维重建算法(Biomedical Optics Express 2012, 3(11), 2916-2936)被生物医学成像领域国际著名专家、德克萨斯大学分子影像中心的Eva M Sevick- Muraca 教授评价为其改进了计算效率和重建图像质量(Phys. Med. Biol. 2014, 59:R1)。




荣誉奖励

第二届“三秦青年科技创新之星”(2020)
国家级青年人才项目(2020)
陕西省****(2020)
陕西省自然科学奖二等奖(2019年度,1/6)
校级优秀教师(2019)
Nature转化影像学会议青年****奖(Nature Biomedical Engineering与ISMI 2019共同主办)
陕西高等学校科学技术奖一等奖(2019, 1/9)
校级优秀教师(2018)
陕西省“特支计划”青年人才项目(2018)
霍英东教育基金会第十六届高等院校青年教师基金(2018)
陕西省青年科技新星(2018)
西安电子科技大学第六届新开发实验及新研制实验设备成果奖(2018, 2/6)
第一届海峡两岸生物医学前沿交叉学术研讨会优秀墙报奖(2017, 国家自然科学基金委与台湾李国鼎发展基金会主办)
西安电子科技大学优秀博士学位论文(2014)
陕西高等学校科学技术奖二等奖(2014, 1/8)
陕西高等学校科学技术奖一等奖(2011, 6/11)
世界分子影像大会旅行资助奖(WMIC 2011, 中国大陆仅6人获得)
教育部高等学校科学研究优秀成果奖科学技术进步奖二等奖(2011, 6/9)
西安电子科技大学优秀博士学位论文资助项目(4万元/年)


学生获奖

2021年西安电子科技大学“挑战杯”校赛一等奖(指导教师)
2020年西安电子科技大学第六届“校长杯”创新创业大赛暨第六届中国“互联网+”大学生创新创业大赛校赛银奖(指导老师)
2019年优秀本科生导学团队(2018-2019学年)
2019年西安电子科技大学第五届“校长杯”创新创业大赛暨第五届中国“互联网+”大学生创新创业大赛校赛银奖(指导老师)
团队入选学校三好三有研究生导学团队
国际学术会议青年学子奖(ISMI 2018):李函蕊、蔡晓霞
国际学术会议最佳摘要奖(ISMI 2018):曹鸿昊
国际学术会议学生旅行资助奖(Student travel award, WMIC):杨德富(2012, 2014)、曹欣(2014)、代云鹏(2016)
西安电子科技大学优秀博士学位论文:曹欣(2018)
研究生国家奖学金:王楠(2019)、李函蕊(2018)、代云鹏(2016)、曹欣(2015, 2014, 2013)、杨德富(2012)
优秀大学生党员:王楠(2019)


发明专利

Xueli Chen, Yonghua Zhan, Nan Wang, Honghao Cao, Duofang Chen, Shouping Zhu, Jimin Liang; Two-mode Raman projection tomography system, US patent: US10,365,219 B1, July 20, 2019.
Jimin Liang, Xueli Chen, Xiaochao Qu, Shouping Zhu, Duofang Chen, Heng Zhao, Jie Tian; System and method for X-ray luminescence computed tomograhpic imaging, US patent, US 10,034,647, July 31, 2018.
陈雪利、曹鸿昊、王楠、鲍翠平、朱守平、梁继民。一种双模态拉曼-光学投影断层成像系统。PCT/CN2018/084672
陈雪利、罗锡鑫、梁继民、詹勇华、陈多芳、曾琦。一种基于频率调制和空间编码的拉曼断层成像系统。ZL6.6,2020.12.01
陈雪利、曹鸿昊、王楠、鲍翠平、朱守平、梁继民。一种双模态拉曼-光学投影断层成像系统。ZL7.3,2020.11.24
陈雪利、代云鹏、孙芳芳、杨德富、梁继民。一种基于体素和自适应光传输模型的光学三维成像方法。ZL5.1,2019.01.29
田捷、陈雪利、刘红波、朱守平、曹旭、陈多芳、梁继民。一种CT/FT/PET三模态同步成像装置。ZL8.0,2016.11.02
陈雪利、孟凡珍、梁继民、张春晖、曹旭、朱守平、田捷。基于多边形视野对称性的旋转双平板PET系统及其成像方法。ZL4.8,2016.09.07
梁继民、陈雪利、屈晓超、朱守平、陈多芳、赵恒、田捷。内窥式X射线发光断层成像装置及方法。ZL7.3,2016.06.22
陈雪利、林叶楠、曹欣、梁继民、屈晓超、曹旭、朱守平、陈多芳、田捷。一种激发荧光双目内窥系统的成像方法。ZL9.4,2016.05.25
陈雪利、曹欣、梁继民、林叶楠、杨德富、屈晓超、陈多芳、田捷。深度与强度可调式的探头激光共聚焦显微内窥镜系统。ZL3.1,2015.08.26
陈雪利、曹欣、梁继民、林叶楠、杨德富、朱守平、屈晓超、陈多芳、田捷。一种医用经内窥镜切伦科夫荧光成像系统。ZL8.7,2015.07.01
陈雪利、张岐坦、梁继民、杨德富、曹欣、陈多芳、朱守平、屈晓超、田捷。一种生物发光断层成像重建方法。ZL7.1,2015.04.08
陈雪利、梁继民、杨德富、朱守平、陈多芳、屈晓超、田捷。一种锥束X射线发光断层成像方法。ZL9.2,2015.01.28
梁继民、陈雪利、田捷、屈晓超、陈多芳、朱守平、赵恒。基于生物组织特异性的光学三维成像方法。ZL0.6,2013.04.03
梁继民、陈雪利、田捷、屈晓超、赵恒、陈多芳、侯彦宾、朱守平、高新波。全光学生物发光断层成像方法。ZLZL2.3,2012.03.28
田捷、陈雪利、梁继民、屈晓超、高新波、赵恒、王琳、刘俊廷。非接触式光学断层成像方法。ZL2.1,2011.04.04




团队教师


在读研究生


博士研究生




研究成果:
论文
1.Nan Wang#, Duofang Chen#, Dan Chen, Cuiping Bao, Jimin Liang, Xueli Chen*,and Shouping Zhu*, “Feasibility study of limited-angle reconstruction for in vivooptical projection tomography based on novel sample fixation,” IEEE Access 2019, 7(1), 87681-87691.
2.Nan Wang#; Honghao Cao#; Lin Wang; Feng Ren; Qi Zeng; Xinyi Xu; Jimin Liang; Yonghua Zhan; Xueli Chen, “Recent advances in spontaneous Raman spectroscopic imaging: instrumentation and applications,”Current Medicinal Chemistry 2020, 27(36), 6188-6207.
3.Nan Wang, Duofang Chen, Cuiping Bao, Jimin Liang, Xueli Chen, and Shouping Zhu*, “Feasibility study of limited-angle reconstruction based in vivo opticalprojection tomography,” SPIE Photonics West 2019, February 2-7, 2019, San Francisco, CA, USA. Oral presentation. Appear in the Three-Dimensional andMultidimensionalMicroscopy: Image Acquisition and Processing XXVI 2019, Proc. of SPIE 2019, 10883, 108830S. DOI: 10.1117/12.**.
4.Nan Wang, Feng Ren, Xu Nie, Xinyu Xu, Qi Zeng, Yonghua Zhan, Shouping Zhu, and Xueli Chen*, “Drug detection in different pharmaceutical dosage forms with Bessel beam-based Raman spectroscopy,” SPIE Photonics West 2021, March 6-11, 2021, San Francisco, CA, USA. Oral Presentation.
会议及口头报告
王楠 2018级博士研究生 1.Nan Wang, Xueli Chen*, Fast stimulated Raman projection tomography (SRPT) by sparse reconstruction from few-view data. 第八届光学方法高级研讨会,广东深圳,口头报告.
研究方向:光学-拉曼投影成像 2.王楠,陈雪利*,基于不完全角度数据稀疏重建的快速受激拉曼投影断层成像。全国第二届生物医学拉曼光谱学术会议,上海,口头报告.
及其应用 3.Nan Wang, Xueli Chen*, Chemical sensing of drugs in scattering media with bessel beam Raman spectroscopy. 第二届全国光子技术论坛,广东广州,口头报告.
邮箱: nwang_2@stu.xidian.edu.cn 4.王楠,陈雪利*,基于贝塞尔光拉曼光谱仪的散射介质中药物检测,第四届光学青年科学家论坛,浙江宁波,poster.
专利
1.Two-mode Raman optical projection tomography system,US 10,365,219 B1
2.一种双模态拉曼-光学投影断层成像系统,PCT/CN2018/084672
3.一种基于空间编码光的拉曼成像系统, 7.0


研究成果:
论文
1.Tianyu Yan#, Qi Zeng#, Lin Wang, Nan Wang, Honghao Cao, Xinyi Xu, Xueli Chen*, “Harnessing the power of optical microscopic and macroscopic imagingfor natural products as cancer therapeutics,” Frontiers in Pharmacology 2019, doi: 10.3389/fphar.2019.01438
2.Tianyu Yan, Feiyang Lu, Duofang Chen, Yonghua Zhan, Jimin Liang, Xueli Chen*, “Raman spectroscopic imaging with frequency modulation based spatially encoded light,” Proceedings of SPIE 2019, doi: 10.1117/12.**
会议及口头报告
1.Tianyu Yan, Xueli Chen*, Raman spectroscopic imaging with frequency modulation based spatially encoded light. 第八届光学方法高级研讨会,广东深 圳,口头报告.
2.闫天宇,陈雪利*,一种用于胃癌早期检测的多模态消化内镜,第二届全国光子技术论坛,广东广州,口头报告.
闫天宇 2019级博士研究生 专利
研究方向:荧光-拉曼双模成像 一种基于空间光编码器联结的契伦科夫内窥镜系统(4.3)
方法及其应用
邮箱:tyyan_128@stu.xidian.edu.cn







康欢 2020级博士研究生
研究方向:计算显微成像及其在病理切片诊断中的应用
邮箱:h.kang@stu.xidian.edu.cn



研究成果:
论文
1.Xueli Chen#,*, Xinyu Wang#, Lin Wang#, Peng Lin, Yonghua Zhan, and Ji-Xin Cheng, "Stimulated Raman scattering signal generation in scattering medium using self-reconstructing Bessel beams," Photonics Research 2020, 8(6), 929-939.
2.Xinyu Wang, Lin Wang, Peng Lin, Hui Xie, Xinyi Xu, Qi Zeng, Yonghua Zhan, and Xueli Chen*, "Simulation of stimulated Raman scattering signal generationin scattering tissues excited by Bessel beams," Journal of Innovative Optical Health Sciences 2021.
会议论文
1.Simulation of the Stimulated Raman scattering signal generation in scattering media excited by Bessel beams. Prof. of SPIE 2020. (oral presentation)
会议及口头报告
1.王鑫宇,陈雪利*,深层生物组织中受激拉曼显微成像仿真的设计与实现。西部光子会议,陕西西安,口头报告。
王鑫宇 2021级博士研究生(2018级硕士研究生)
研究方向:契伦科夫内窥镜、激光共聚焦显微内镜
邮箱:xyuwang@stu.xidian.edu.cn



李宇 2021级博士研究生
邮箱:lyyyyy9605@163.com


硕士研究生


2019级硕士研究生





2020级硕士研究生





2021级硕士研究生




已毕业研究生

王汇元:北京航空航天大学博士研究生
2018级硕士研究生
毕业时发表第三作者文章1篇(指导教师为前两共同作者,IEEE Trans. Biomed. Eng.), 共一文章1篇(AIP Advance), 国际会议论文1篇(SPIE, Oral)

王浩宇:深圳迈瑞生物医疗电子股份有限公司
2018级硕士研究生
毕业时发表第二作者国际会议论文1篇(SPIE)

任枫:中国移动通信集团湖南有限公司
2018级硕士研究生
毕业时发表第一作者国际会议论文1篇(SPIE, Oral), 第二作者国际会议论文1篇(SPIE, Oral), 受理中国发明专利3项

罗锡鑫:招商网络科技有限公司
2018级硕士研究生
毕业时发表第一作者国际会议论文1篇(SPIE, Oral),第二作者国际会议论文1篇(指导教师为第一作者, SPIE), 授权中国发明专利1项, 受理中国发明专利1项

刘一超:余姚舜宇智能光学
2018级硕士研究生

聂旭:上海艾瑞德生物科技公司
2018级硕士研究生
毕业时发表第三作者SCI论文1篇(planta medica),共一作者发表国际期刊论文2篇(journal of bio-x),第二作者发表国际期刊论文1篇(journal of bio-x)

曹鸿昊:深圳华为
2017级硕士研究生
毕业时发表共一作者SCI论文1篇(Curr.Med. Chem.),第二作者SCI论文1篇(IEEE Access),授权美国专利1项、PCT国际专利1项,受理中国发明专利1项,软件著作权2项,国际学术会议口头报告1次

鲍翠平:西安圆周率信息科技有限公司
2015级硕士研究生
毕业时发表第二作者SCI论文1篇(指导教师为第一作者,IEEE Trans. Biomed. Eng.)

代云鹏:西安华为
2013级博士研究生;2016年研究生国家奖学金;2016年世界分子影像大会旅行资助奖
毕业时发表第一作者SCI论文2篇(Biomed. Opt. Express、J. Biomed. Opt.),在审3篇(Biomed. Opt. Express、IEEE Trans. Biomed Eng.、Phys. Med. Biol.;在审分别于2018年发表于Biomed. Opt. Express、2019年发表于IEEE Trans. Biomed Eng.、2020年发表于Quantat. Imaging Med. Surg.)。

曹欣:西北大学,副教授
2012级博士研究生;2013、2014、2015年研究生国家奖学金;2014年世界分子影像大会旅行资助奖;校级优秀博士学位论文
毕业时发表第一作者SCI论文4篇(ACS Appl. Mater. Inter., Appl. Phys. Lett., Biomed. Opt. Express, Current Med. Imaging Rev.)

孙芳芳:廊坊新奥集团
2013级硕士研究生
毕业时发表第二作者SCI论文2篇(指导教师为第一作者,Phys. Med. Biol., J. Biomed. Opt.)

杨德富:杭州电子科技大学,讲师
2011级博士研究生;2012年研究生国家奖学金;2012、2014年世界分子影像大会旅行资助奖
毕业时发表第一作者SCI论文5篇(Biomed. Opt. Express, Appl. Opt., Med. Biol. Eng. Comput., JINST, IEEE Trans. Biomed. Eng.)





团队2021年研究生招生已结束!欢迎大家咨询报考2022年研究生。
~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~
研究生招生信息:
预计每年招收硕士研究生7-8名(生物医学工程专业,学硕和专硕),博士研究生1-2名(生物信息科学与技术专业)。请计划报考的同学能报考前联系,做初步的面试,要求至少在数学、英语、软硬件开发等方面有某一方面的特长,最好有辅证材料。满足如下要求之一者优先考虑:
(1)具有良好的数学基础,并愿意继续攻读博士学位者;
(2)具有良好的英语水平者(英文读写、交流能力);
(3)具有光学工程、医学、生化相关背景者;
(4)参加过数学类竞赛、程序设计大赛,并取得较好成绩者。
对考生的要求:
(1)品行端正、积极主动、能吃苦,有坚韧不拔的毅力,具有团队协作意识;
(2)建议有以下特点的同学不好报考:准备混学位者、消极厌世者、不思进取者、依赖性强者;
(3)报考前请大家通过邮件(xlchen@xidian.edu.cn,同时抄送徐老师xyxu@xidian.edu.cn)与我们联系,以确定名额是否还有空缺。
也欢迎对科研有兴趣的本科生加入我们研究组,参与项目,或者在研究组支持下做自己感兴趣的课题。
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教师岗位招聘
生物医学光子学与分子影像研究室诚聘全球英才
研究室长期招聘生物医学成像领域华山****菁英教授、菁英副教授、准聘副教授、讲师和博士后若干名,包括但不限于光学工程、光学分子影像、超声/光声成像、成像与检测探针等相关背景。要求具有光学工程、超声、医学成像、化学、大数据分析相关专业博士学位,有拉曼/SERS、共聚焦、双光子、超声/光声、生物信息学等相关研究经验者优先考虑。有兴趣加入研究室的优秀博士和在站博士后请与我邮件(xlchen@xidian.edu.cn,同时务必抄送曾老师qzeng@xidian.edu.cn)联系。
基本条件:须具有博士研究生学历。身心健康。具备为人师表的基本素质。遵守中华人民共和国宪法和有关法律规定,有强烈的事业心和高度的责任感,热爱高等教育事业。取得同行专家认可的科研成果,且具有一定的发展潜力。全职来校工作。
入职学科方向:生物医学成像方向
入职岗位:华山****菁英教授、菁英副教授、准聘副教授,教学科研并重岗,博士后。
招聘学科:生物医学工程、光学工程、化学、生物、医学、药学、电子信息、人工智能等相关学科。
研究背景:生物医学成像、光学显微成像(拉曼/SERS、共聚焦、双光子等)、分子影像、生物医学大数据及其他相关研究方向。




新闻动态
目前接收2021级研究生!
?[2021-6-27]2021年6月27日,团队负责人陈雪利教授受山东大学马晓鹏教授邀请到山东大学智能医学工程研究中心学术交流,并作题为“基于贝塞尔光束的深度扩展型拉曼光谱成像技术”的邀请报告。

?[2021-6-25]2021年6月25日,团队负责人陈雪利教授受浙江大学钱骏教授邀请到浙江大学光电学院学术交流,并作题为“多尺度定量光学分子成像”的邀请报告。

?[2021-6-20]2021年6月20日到6月25日,团队负责人陈雪利教授被选派前往浙江大学继续教育学院参加陕西省教工委组织的基层党支部书记培训,并顺利结业。

?[2021-6-15]Congratulations!祝贺团队陈雪利教授、王鑫宇同学关于信号增强型契伦科夫荧光内窥镜的文章被Quantitative Imaging in Medicine and Surgery接收(中科院医学II区)。祝贺!

?[2021-6-3]2021年6月3日,团队教师谢晖副教授受邀参加西南交大承办的2021年四川省一流课程建设培训会,并作了以“新工科智能信息化混合式一流课程的建设及申报”为题的大会报告。
https://mp.weixin.qq.com/s/owUg6L1kqp-ayucbZmYFKA
https://mp.weixin.qq.com/s/2GfEko58byKY4fWO8LqdtA

?[2021-5-25]Congratulations!祝贺团队研究生王汇元、罗锡鑫、任枫、刘一超、王浩宇、聂旭同学顺利通过硕士学位论文答辩!希望大家在未来工作岗位继续发扬和传承BMI精神和文化,努力、踏实工作,前程似锦!
王鑫宇 西安电子科技大学博士研究生
王汇元 北京航空航天大学博士研究生
王浩宇 深圳迈瑞生物医疗电子股份有限公司
罗锡鑫 招商网络科技有限公司
任枫 中国移动通信集团湖南有限公司
刘一超 余姚舜宇智能光学
聂旭 中国银行软件中心(西安)

?[2021-5-20]2021年5月20日,为庆祝中国共产党成立100周年,学校举行百名党员过“政治生日”仪式,团队负责人陈雪利教授受邀在仪式暖场视频中进行“共话入党初心”的采访。
https://mp.weixin.qq.com/s/nsnU-sCUQQLx-H-fpZQZOA

?[2021-4-21]Congratulations!祝贺团队陈多芳副教授、王朝晖同学关于基于无透镜计算成像+深度网络的细胞分类文章被Quantitative Imaging in Medicine and Surgery接收(中科院医学II区)。祝贺!

?[2021-4-4]热烈祝贺闫胚娆、杨慧婷、黄鹏飞、彭扬尧、孟煜、孙致远、关慧迪、张健、林江涛通过研究生复试!!欢迎夏冉、闫胚娆、杨慧婷、黄鹏飞、彭扬尧、孟煜、孙致远、关慧迪、张健、林江涛加入BMI Lab大家庭!!!

?[2021-3-31]2021年3月31日,陕西省教育厅公示了入选陕西省课程思政示范课、课程思政教学示范团队名单,团队教师谢晖副教授负责的《现代工科微生物学》成功入选省级课程思政示范课,教学团队入选省级课程思政教学示范团队。
http://jyt.shaanxi.gov.cn/news/gsgg/202103/31/18918.html

?[2021-3-23]2021年3月23日,2021年度陕西省科技计划项目立项名单公示,团队教师曾琦副教授牵头申报的关于中医药传承创新发展关键技术重点产业创新链(重点研发计划)项目获得资助,资助金额为100万元。这是团队获批支持的第一个陕西省重点研发计划项目。祝贺!

?[2021-3-9]2021年3月9日,学校公布了“研究生导学思政育人机制改革创新试点团队”立项结果,团队成功入选首批研究生导学思政育人创新试点团队。祝贺!

?[2021-1-15]2021年1月15日,“三好三有”研究生导学团队系列活动暨生物医学光子学与分子影像研究室2020年终总结和2021年计划会(2020年度总结表彰会)在南校区G418会议室成功举行。研究室研二、研三和博士生对2020年度的工作进行了总结汇报,并对2021年的工作做了规划;研究室全体老师对学生们的工作进行点评,并评选出BMI特殊贡献奖、BMI成果奖、BMI事务奖、BMI团建运动奖以及BMI奖状奖杯设计奖。
BMI特殊贡献奖:用于表彰对研究室有突出贡献的BMI Lab学子!获得本年度BMI突出贡献奖的同学是王鑫宇,成果发表于Photonics Research,实现研究室I区文章的突破(光学I区,中国期刊)。
BMI成果奖:用于表彰积极参与科研,并取得较高科研成果的BMI Lab学子!获得本年度BMI成果奖的同学有王楠、王鑫宇、刘慧芳、闫天宇、曹鸿昊、罗艳霞。
BMI事务奖:用于表彰积极参与研究室公共事务的BMI Lab学子!获得本年度BMI事务奖的同学有王楠、王鑫宇、刘慧芳、王浩宇、闫天宇、范大玮、聂旭、郑运。
BMI团建运动奖:用于表彰积极参与研究室每周的体育锻炼,并参与次数排在前三的BMI Lab学子!获得本年度BMI团建运动奖一等奖的同学有韩明、刘慧芳;二等奖的同学有王鑫宇;三等奖的同学有常鹏、郑运。
BMI奖状奖杯设计奖:用于表彰本年底所有奖状奖杯的设计者。本年度该奖项的获得者是王汇元。
祝贺上述同学,其他同学2021年继续努力,争取进入榜单!!!

?[2021-1-11]Congratulations!2018级硕士研究生王鑫宇同学关于贝塞尔光受激拉曼显微成像术在散射组织中的仿真研究成果被光学领域重要中国期刊Journal of Innovative Optical Health Sciences接收。这是鑫宇同学的第二篇SCI论文,祝贺!

?[2021-1-8]Congratulations!近日团省委统战部公布了第二届“寻找最美三秦青年科技之星”入选者,研究室负责人陈雪利教授入选第二届“三秦青年科技创新之星”。祝贺!
https://mp.weixin.qq.com/s/a-sIfbp836zHpXwj0j3n1A
https://www.toutiao.com/i69**799373
https://mp.weixin.qq.com/s/TD3RQSUzIRVzSE4F9uPY6g (人才陕西)

?[2020-12-28]2020年12月28日,团队青年教师谢晖副教授获得了学校首届本科教学创新奖二等奖(一等奖空缺)!!!

?[2020-12-28]2020年12月26-28日,研究室陈雪利教授、徐欣怡和曾琦副教授受邀参加在宁波举办的“中国生物物理学会材料生物学与智能诊疗技术分会青年****年会暨2020年生物医学材料与技术交叉青年论坛”,并作题为“定量光学分子成像技术:理论、方法与应用”“基于基因密码子扩展的纳米抗体探针用于肿瘤成像研究”的邀请报告。

?[2020-12-24]Congratulations!祝贺团队教师谢晖副教授的论文《基于网络微平台教学的微生物学实验精细化及个性化教学改革》入选《微生物学通报》2019年度优秀论文。

?[2020-12-20]Congratulations!祝贺团队教师谢晖副教授荣获第二届全国高校混合式教学创新设计大赛一等奖,这是西电首次在该赛事上荣获一等奖,也是陕西高校在本届大赛中荣获的唯一一等奖。
https://news.xidian.edu.cn/info/2106/212305.htm
近年来谢晖副教授致力于人工智能教育信息化研究工作,取得了系列成果:
入选国家级线上线下混合式本科一流课程(2020)
全国高校混合式教学创新设计大赛全国一等奖(2020)
2020新时代高校生命科学教学改革于创新研讨会邀请报告(2020)
国际化MOOC课程(国家级, 2020)
微生物学国家MOOC课程(2019)
陕西省疫情期间在线教学典型案例(2020)
获批陕西省疫情防控应急研究项目(2020)
陕西省首届课堂教学创新大赛一等奖(2018)
陕西省省级示范性虚拟仿真实验教学项目(陈雪利、谢晖, 2018)

?[2020-12-09]热烈祝贺王鑫宇通过2021春博士研究生入学复试!!!

?[2020-12-06]2020年12月5-7日,研究室陈雪利教授、周王婷博士受邀参加在宁波举办的第四届光学青年科学家论坛,并作题为“深度网络辅助的个位数投影断层成像方法(陈雪利)”、“光声/OCT引导动脉粥样硬化斑块的脂质选择性消融术(周王婷)”的学术报告。

?[2020-12-04]2020年12月4日,研究室负责人陈雪利教授牵头获批了学校2021年基本科研业务费扶贫专项(科技扶贫类)重点类项目资助,资助经费12万元用于开发金银花药效成分和农残检测设备。

?[2020-12-02]2020年12月2日,先进医学影像党支部/生物医学光子学与分子影像研究室举办了精准医学青年科学家论坛,深圳大学宋军教授、中山大学附属第五医院李丹研究员、西电物理与光电工程学院郜鹏教授、西电生科院吕锐婵教授、复旦大学季敏标教授(线上)参加论坛并作学术报告。

?[2020-11-30]研究室负责人陈雪利教授受邀到华南师范大学生物光子学研究院交流,并作题为“多尺度定量光学分子成像”的学术报告。

?[2020-11-29]研究室博士生闫天宇、王楠参加在广州举办的第二届全国光子技术论坛,并在论文生物医学光子学专题做口头报告(“一种用于胃癌早期检测的多模态消化内镜”-闫天宇、“基于贝塞尔光拉曼光谱仪的散射介质中药物检测”-王楠)。

?[2020-11-16]受研究室负责人陈雪利教授邀请,成都上锦南府医院/四川大学华西医院上锦医学实验医学科主任曾婷婷副主任医师来访,并作题为“医工结合——现代检验医学的必由之路”的学术报告。

?[2020-11-16]Congratulations!祝贺研究室负责人陈雪利教授入选国家级青年人才项目!!!

?[2020-11-11]2020年11月11日,SPIE Photonics West 2021结果出炉,研究室投稿1篇摘要被录用为oral presentation。祝贺王楠!!!

?[2020-11-02]研究室陈雪利教授、徐欣怡副教授受邀到慈溪医工所做学术交流,并作题为“光学分子影像技术的临床应用探索:从契伦科夫荧光内窥镜到多模态跨尺度内镜”的学术报告。

?[2020-10-31]2020年10月31日,先进医学影像党支部/先进医学影像“三好三有”研究生导学团队举办了第二届智能医学影像学术论坛暨2020年研究生学术年会,北京工业大学冯金超、浙江大学钱骏、西安交通大学吴荣谦、空军军医大学西京医院康飞、西电计算机学院马小科参加论坛并作学术报告;论坛共收到研究生论文投稿26件,最终入选12篇口头报告。

?[2020-10-30]Congratulations!研究室关于人工智能教育信息化工作发表于国内权威期刊《现代教育技术》,论文第一作者为研究室青年教师谢晖副教授,通讯作者为研究室负责人陈雪利教授。《现代教育技术》时CSSCI和北大核心期刊,年发文量197篇,接受率仅为2%。详见网页新闻:https://www.xidian.edu.cn/info/2270/43997.htm

?[2020-08-07]研究室负责人陈雪利教授受邀做卓立汉光名师讲堂邀请报告(贝塞尔光束在拉曼光谱成像技术中的应用)。

?[2020-07-04]受研究室负责人陈雪利教授邀请,华南师范大学杨思华教授给团队及学院师生以腾讯会议直播形式作题为“光声显微及内窥成像技术及其医学应用研究”的学术报告。

?[2020-06-02]研究室陈雪利教授与曾琦、谢晖副教授受邀前往商洛学院生物医药与食品工程学院交流,并作题为“天然活性物质的发现与功能评价”学术报告。

?[2020-05-27]热烈祝贺康欢、杜戈涛通过博士研究生入学复试!!!

?[2020-05-27]热烈欢迎韩明、刘瑞、张娇娇、贺江山、张瑞瑞、陈凯、张鹏源加入成像课题组;同时欢迎李丽、刘思婷、王庆雅、仪同、康雪晴、王莹、常鹏加入BMI Lab!!!

?[2020-05-25]热烈祝贺实验室研究生曹鸿昊、蔡晓霞、施科如、刘新玥、田振超顺利通过硕士学位论文答辩!!!

?[2020-04-17]实验室关于基于贝塞尔光的受激拉曼显微成像在散射介质中的应用论文已在Photonics Research (中科院I区,光学I区,中国期刊)上在线发表;欢迎老师同学们下载阅读:http://www.clp.ac.cn/EN/Article/OJd82de**b5c

?[2020-04-17]Congratulations!4月16日,陕西省人民政府发布了《陕西省人民政府关于2019年度陕西省科学技术奖励的决定》,研究室陈雪利教授牵头完成的“面向胃癌早期检测的定量光学分子成像新方法”获得陕西省自然科学奖二等奖!祝贺!!!
https://mp.weixin.qq.com/s/_7n7Huz_CMP5cL-E_PvAsA

?[2020-04-03]Congratulations!近日2020年陕西省科技计划项目公布,研究室负责人陈雪利教授获得陕西省****科学基金项目(陕西省****)资助!祝贺!!!

?[2020-03-25]Congratulations!研究室关于基于贝塞尔光的受激拉曼显微术在散射组织中的应用论文被Photonics Research (中科院I区,光学I区)接收!

?[2020-01-06]2020年01月06日,研究室举办了“不忘初心、砥砺奋进”2019年生物医学光子学与分子影像研究室年会,同学们以各种才艺表演方式对2019年工作进行总结,反响极好!

?[2020-01-03]2020年01月03日,研究室举办主题为“Look back on 2019, look forward to 2020”年终总结计划会,并对在2019年做出贡献的同学颁发“科技成果奖”和“小蜜蜂事务奖”;研究室并正式更名为"生物医学光子学与分子影像研究室BMI Lab"。

?[2019-12-21]2019年12月21日,研究室负责人陈雪利教授应邀参加第十一届西部光子学会议,并被邀做分会场主持人(主持专题:微纳光子学、信息光子学技术与应用、空天光学与光电工程,陕西西安);同时研究室研究生王鑫宇(研二)和范大玮(研一)应邀在会上作口头报告,报告题目分别为"深层生物组织中受激拉曼显微成像仿真的设计与实现"和"基于硅光电倍增管的共聚焦激光扫描显微镜的设计与实现"。

?[2019-12-13]Congratulations!研究室代云鹏博士关于动态生物发光定量方法的论文被Quantitative Imaging in Medicine and Surgery接收!

?[2019-11-28]Congratulations!研究室博士研究生闫天宇(博一)关于光学分子成像技术在天然药物抗癌作用中应用的综述论文在Frontiers in Pharmacology (中科院II区)上发表!

?[2019-11-05]Congratulations!研究室陈多芳博士关于契伦科夫荧光图像去噪的论文被Medical & Biological Engineering & Computing接收!

?[2019-10-26]Congratulations!研究室负责人陈雪利教授Nature转化影像学会议青年****奖;该会议是有Nature期刊与ISMI2019共同承办,获奖者由Nature Biomedical Engineering期刊邀请专家评出。

?[2019-10-24]2019年10月23-25日,研究室负责人陈雪利教授应邀参加第二届海峡两岸生物医学前言交叉研讨会(中华台北),并作邀请报告:Quantitative biophotonic imaging: a platform for gastric cancer detection。

?[2019-10-01]2019年10月1日,SPIE Photonics West 2020结果出炉,研究室投稿4篇摘要均被录用,其中2篇选为oral presentation。

?[2019-09-24]Congratulations!2019年9月24日,研究室博士生王楠顺利通过学院研究生国奖答辩,获得2018-2019年度博士生国家奖学金。

?[2019-08-22]2019年8月22-25日,研究室曾鋆、徐欣怡、陈雪利应邀参加中国生物材料大会暨中国生物医学工程学会生物材料分会年会(辽宁大连),并作墙报快速演讲:A photo-triggered conjugation approach for attaching RGD ligands to biodegradable mesoporous silica nanoparticles for the tumor fluorescent imaging。

?[2019-08-20]2019年8月19-21日,研究室徐欣怡应邀参加中国生物医学工程学会大连青年论坛(辽宁大连),并作邀请报告:新型靶向分子荧光探针成像研究。

?[2019-08-20]2019年8月19-21日,研究室负责人陈雪利教授应邀参加中国生物医学工程学会大连青年论坛(辽宁大连),并作邀请报告:基于贝塞尔光束的深度扩展型受激拉曼显微成像方法。

?[2019-08-16]Congratulations!研究室研究生谢晖、王汇元关于稀疏投影重建方法的论文在AIP Advances上发表!

?[2019-08-12]Congratulations!研究室关于稀疏受激拉曼投影断层成像方法的论文被IEEE Transactions on Biomedical Engineering(中科院II区)接收!

?[2019-08-10]研究室负责人陈雪利教授应邀参加中国光学学会学术大会(安徽合肥),并在生物医学光子学专题作邀请报告:基于贝塞尔光的散射介质中受激拉曼显微成像。

?[2019-07-30]Congratulations!研究室获授权一项关于双模态拉曼-光学投影成像系统的美国发明专利(US 10,365,219 B1)。

?[2019-07-06]研究室负责人陈雪利教授应邀参加第一届分子与神经影像、智能影像与质量安全专题学术会议(江苏镇江),并作邀请报告:光学分子影像及其在胃肠道临床检测中的转化应用探索。

?[2019-06-13]Congratulations!研究室博士生王楠同学关于光学投影断层成像的论文被IEEE Access(中科院II区)接收!

?[2019-05-30]2019年5月24-30日,恭喜研究室做本科毕设的四位同学顺利通过本科学位论文答辩,获得一优(范大玮)三良的好成绩。

?[2019-04-26]2019年4月26-28日,研究室负责人陈雪利教授参加中国生物医学工程学会第二届生物医学光子学分会会员代表大会暨学术交流会(海口)。

?[2019-04-23]2019年4月23日,西电生命科学技术学院公示了2019级硕士研究生录取名单,恭喜和欢迎四位新成员:范大玮、郑运、罗艳霞、郝文卿!

?[2019-04-18]2019年4月18日,恭喜研究室徐欣怡博士关于光点击偶联的荧光纳米探针的论文被Nanomedicine-Nanotechnology Biology and Medicine接收!

?[2019-03-26]2019年3月26日,恭喜王汇元同学投稿The 12th International Symposium on Photonics and Optoelectronics (SOPO 2019)的摘要被录用并选为oral presentation!

?[2019-01-21]2019年1月21-23日,研究室陈雪利教授、詹勇华副教授参加“先进超声技术在极端环境应用”高峰论坛(深圳)。

?[2019-01-12]研究室举办主题为“Look back on 2018, look forward to 2019”年终总结计划会,并对在2018年做出贡献的同学颁发“科技成果奖”和“小蜜蜂事务奖”。

?[2018-12-21]研究室负责人陈雪利教授应邀到西安交通大学交流,并作题为“多尺度定量生物光学成像”的学术报告。

?[2018-12-08]2018年12月7-10日,研究室王楠、任枫参加全国第二届生物医学拉曼光谱学术会议(上海),其中王楠在会上做题为“Fast stimulated Raman projection tomography (SRPT) by sparse reconstruction from few-views data”口头报告。

?[2018-11-21]研究室负责人陈雪利教授应邀到西安医学院基础与转化医学研究所交流,并作题为“光学分子成像技术及其转化医学应用”的学术报告。

?[2018-11-07]2018年11月5-7日,研究室徐欣怡博士、蔡晓霞参加生物医学材料国际合作论坛暨第十届全国低场核磁共振技术与应用研讨会(宁波),其中蔡晓霞(研二)在会上做“Radiolabeled, Antibody-Conjugated Manganese Oxide Nanoparticles for Tumor Vasculature Targeted Positron Emission Tomography and Magnetic Resonance Imaging”口头报告。

?[2018-11-05]2018年11月5-9日,研究室陈雪利教授、陈多芳副教授、王楠、曹鸿昊、闫天宇参加第八届光学方法高级研讨会(深圳, AOWM 2018),其中王楠(博一)、曹鸿昊(研二)、闫天宇(研二)分别在会上做英文口头报告。

?[2018-10-28]Congratulations!祝贺研究室研究生李函蕊(博一)、蔡晓霞(研二)获第二届珠海分子影像国际论坛“青年学子奖”,曹鸿昊(研二)获第二届珠海分子影像国际论坛“最佳摘要奖”。

?[2018-10-28]2018年10月27-28日,研究室负责人陈雪利教授应邀参加第二届珠海分子影像国际论坛,并做了题为“Quantitative Biophotonics Imaging: a platform for gastric cancer detection”的特邀报告。

?[2018-10-26]Congratulations!研究室作为课题二承担单位和课题一参与单位参与的国家重点研发计划精准医学专项在珠海启动,项目总经费为1923万,其中研究室承担经费为385万元。

?[2018-10-01]Congratulations!课题组投稿SPIE Photonics West的6篇摘要均被录用,其中5篇录用为oral presentation,1篇录用为poster presentation。恭喜王楠(博一)、闫天宇(研二)、王汇元(研一)、王鑫宇(研一)、罗锡鑫(研一)、曹鸿昊(研二)同学。

?[2018-09-18]2018年9月11-17日,课题组陈雪利教授、詹勇华副教授、李函蕊博士参加了在美国西雅图举办的世界分子影像大会(WMIC 2018)。

?[2018-09-18]Congratulations!祝贺研究室博士生李函蕊获得国家奖学金!

?[2018-07-18]Congratulations!课题组代云鹏博士关于动态生物发光定量成像的论文被IEEE Transactions on Biomedical Engineering(中科院II区)接收!

?[2018-04-27]Congratulations!课题组博士生李函蕊关于荧光纳米探针的论文被Nanomedicine-Nanotechnology Biology and Medicine(中科院I区)接收!

?[2018-03-31]Congratulations! 陈雪利教授入选陕西省首批青年拔尖人才!!!祝贺!!!

?[2018-03-18]Congratulations!课题组博士生代云鹏的关于定量动态荧光成像的论文被Biomedical Optics Express接收!

?[2018-03-04]Congratulations! 陈雪利教授获批“霍英东教育基金会第十六届高等学校青年教师基金资助项目”!!!祝贺!!!

?[2018-01-12]Congratulations!陈雪利教授主持申报的“2017年新实验开发与新实验设备研制教改项目”获批。

?[2017-12-09]Congratulations!恭喜课题组博士生代云鹏顺利通过博士学位论文答辩!!!

?[2017-12-01]陈雪利教授为子课题负责人的国家自然科学基金重大科研仪器研制项目在天津顺利完成年度学术交流会议,陈雪利教授和詹勇华副教授参加了交流会。

?[2017-12-01]第十九届全国光散射学术会议在广州召开,课题组成员王楠、蔡晓霞参加。

?[2017-11-17]应陈雪利教授邀请,美国波士顿大学的Delong Zhang博士来学院访问交流,并做了题为“Chemical Imaging with Molecular Vibrational Fingerprint”的学术报告。

?[2017-11-16]陈雪利教授应陕西省科技厅要求参加第二届“丝绸之路青年****分论坛”陕西科技创新分论坛。

?[2017-11-15]应陈雪利教授邀请,澳大利亚卧龙岗大学的Shiyang Tang博士来学院访问交流,并做了题为“Gallium-based Liquid Metals in Microfluidics”的学术报告。

?[2017-11-05]陈雪利教授参加了在苏州召开的第4届国际医学影像研讨会。

?[2017-11-03]Congratulations!课题组负责人陈雪利教授入选2017年陕西省留学人员科技活动择优资助优秀类资助项目。

?[2017-10-16]第一届海峡两岸生物医学前沿交叉学术研讨会在西安召开,课题组成员参加,并获最佳墙报奖。

?[2017-09-28]陈雪利教授参加了在苏州召开的第14届生物&医学光子学与成像国际会议(PIBM 2017),并应邀作为Best Poster Award的评审组成员。

?[2017-08-28]课题组负责人陈雪利教授应邀参加第二届生物医学成像新技术新方法青年论坛(西安曲江),并做了题为“基于受激拉曼投影成像的三维显微容积成像方法”的特邀报告。

?[2017-07-27]Congratulations!课题组负责人陈雪利教授入选2018年度陕西省青年科技新星!

?[2017-06-08]课题组负责人陈雪利副教授牵头申请的“三一流”建设经费获学院支持,经费150万,用于搭建多尺度拉曼显微成像系统。

?[2017-06-07]Congratulations!课题组负责人陈雪利副教授顺利通过学校职称破格答辩,年限破格晋升为教授!

?[2017-05-12]陈雪利副教授为子课题负责人的国家自然科学基金重大科研仪器研制项目在南京春晖公司召开第二次项目研讨会。

?[2017-04-24]以课题组负责人陈雪利副教授为子课题负责人的国家自然科学基金重大科研仪器研制项目到款110万!

?[2017-04-15]陈雪利副教授为子课题负责人的国家自然科学基金重大科研仪器研制项目启动会在西安•西京医院顺利召开。

?[2017-03-31]课题组获批1项基本科研业务费项目,经费8万元。

?[2017-03-30]祝贺曹鸿昊、王楠、孙冠杰、闫天宇四位同学顺利通过研究生面试,正式加入课题组。

?[2017-03-15]课题组负责人陈雪利副教授从美国普渡大学访学归来,开始组建生物光学成像、分析与应用实验室。

?[2017-03-02]Congratulations!!!课题组负责人陈雪利副教授的文章“Volumetric chemical imaging by stimulated Raman projection microscopy and tomography”被Nature Communications接收,这是西电首篇以第一单位发表的Nature子刊论文。







Profile
Xueli Chen, Ph.D., Professor
Director of Biomedical-photonics & Molecular Imaging Lab
Affiliation: School of Life Science and Technology, Xidian University

Contact Information
Address: 266 Xinglong Section of Xifeng Road, Xi\'an, Shaanxi 710126, China
Email: xlchen at xidian.edu.cn
Tel: 86-

Teachning
Course for Undergraduate
Medical Instrumentation
Calculation Method
Course for Graduate
Biomedical Photonics
Advanced Medical Instumentation

Awards & Honors
Second Prize of Natural Science Award of Shaanxi Province
Young Investigator Award of the Nature Conference on Translational Imaging (with ISMI 2019)
First Prize of Science & Technology Award in Shaanxi Universities
Young Top-notch Talent of Special Support Plan in Shaanxi Province
Young Teacher Fund of Fok Ying-Tong Education Foundation of China
Young Star of Science and Technology of Shaanxi Province


Introduction
Xueli Chen, Professor of Xidian University, Director of Biomedical-photonics & Molecular Imaging Lab. Chen carried out his undergraduate and doctoral studies at Xidian University of China from 2003 to 2012. Chen received his Bachelor degree in Biomedical Engineering and PhD degree in Pattern Recognition and Intelligent System in 2007 and 2012 respectively. His doctoral dissertation was selected as the Excellent Doctoral Dissertation of Xidian University. Chen joined Xidian University in 2012 as Assistant Professor in School of Life Science and Technology, promoted to Associate Professor in 2014 and Full Professor in 2017. During 2015 to 2017, he worked as a research postdoctoral fellow at Purdue University (Ji-Xin Cheng\'s group) on stimulated Raman scattering microscopy. Chen and his team have been constantly at the most forefront of multiscale biomedical photonics imaging in innovation, application, and clinical translation.Professor Chen has co-led the development of Cerenkov luminescence endoscope and further explored the application in early detection of clinical gastrointestinal tumors. Professor Chen has also developed the stimulated Raman projection tomography technology which can perform the volumetric imaging of single cells in a label-free manner. Professor Chen has served as the member of SPIE, OSA, IEEE, and as a committee member of the Branch of Contrast Technology in China Medicinal Biotech Association, the Nuclear Medicine Committee of Shaanxi Cancer Association, and the Shaanxi Society of Biomedical Engineering.

Selectedrepresentative papers
Xueli Chen#,*, Xinyu Wang#, Lin Wang#, Peng Lin, Yonghua Zhan, and Ji-Xin Cheng, “Stimulated Raman scattering signal generation in scattering medium using self-reconstructing Bessel beams,” Photonics Research 2020, in press. (Raman)
Xueli Chen#,*, Shouping Zhu#, Huiyuan Wang, Cuiping Bao, Defu Yang, Chi Zhang, Peng Lin, Ji-Xin Cheng, Yonghua Zhan, Jimin Liang, and Jie Tian, “Accelerated stimulated Raman projection tomography by sparse reconstruction from sparse-view data,” IEEE Transactions on Biomedical Engineering 2020, in press. DOI: 10.1109/TBME.2019.** (Raman)
Yunpeng Dai#, Guodong Wang#, Duofang Chen, Jipeng Yin, Yonghua Zhan, Yongzhan Nie, Kaichun Wu, Jimin Liang*, and Xueli Chen*, “Intravenous administration-oriented pharmacokinetic model for dynamic bioluminescence imaging,” IEEE Transactions on Biomedical Engineering 2019, 66(3), 843-847. Mar. 2019. (Quantification)
Xueli Chen#, Chi Zhang#, Peng Lin, Kai-chih Huang, Jimin Liang, Jie Tian, and Ji-Xin Cheng*, “Volumetric chemical imaging by stimulated Raman projection microscopy and tomography,” Nature Communications 2017, 8, 15117. Apr. 24, 2017. (Raman)
Xueli Chen#, Defu Yang#, Fangfang Sun, Xu Cao, and Jimin Liang*, “Adaptively alternative light-transport-model-based three-dimensional optical imaging for longitudinal and quantitative monitoring of gastric cancer in live animal,” IEEE Transactions on Biomedical Engineering 2016, 63(10), 2095-2107. Oct. 1, 2016. (Quantification)
Xin Cao#, Xueli Chen#, Fei Kang#, Yonghua Zhan, Xu Cao, Jing Wang*, Jimin Liang*, and Jie Tian*, “Intensity enhanced Cerenkov luminescence imaging using terbium-doped Gd2O2S microparticles,” ACS Applied Materials & Interfaces 2015, 7(22), 11775-11782. Jun 10, 2015. DOI: 10.1021/acsami.5b00432. (Cerenkov endoscope)
Hao Hu#, Xin Cao#, Fei Kang#, Min Wang, Yenan Lin, Muhan Liu, Shujun Li, Liping Yao, Jie Liang, Jimin Liang, Yongzhan Nie, Xueli Chen*, Jing Wang*, Kaichun Wu*, “Feasibility study of novel endoscopic Cerenkov luminescence imaging system in detecting and quantifying gastrointestinal disease: first human results,” European Radiology 2015, 25(6), 1814-1822. May 2015. (Cerenkov endoscope)
Xueli Chen, Xinbo Gao*, Duofang Chen, Xiaopeng Ma, Xiaohui Zhao, Man Shen, Xiangsi Li, Xiaochao Qu, Jimin Liang, Jorge Ripoll, and Jie Tian*, “3D reconstruction of light flux distribution on arbitrary surfaces from 2D multi-photographic images,” Optics Express 2010, 18(19), 19876-19893. Sep. 13, 2010. (Quantification)

Research Interests
We develop multiscale, quantitative optical imaging technologies from micro to macro scale at cell-animal-human level, and apply these technologies to enable early detection and accurate diagnosis of cancers. With integrated expertise in engineering, electronic information, optics, chemistry, biology, and medicine, our lab focuses on:
Raman-based high resolution, label-free dynamic imaging technology
Multiscale, multimodality optical-Raman projection tomography/Raman sheet-projection tomography
Fast, high-resolution coherent Raman scattering microscopic imaging
Raman probe-based CW stimulated Raman scattering microscopy
Bessel beam excited porable Raman spectroscopic imaging
Len-free mode-based computational microscopic imaging technology (Flow cytometry imaging)
Fluorescence-based high resolution microscopic imaging technology
Confocal based microscopic imaging (endoscopy, super resolution, confocal)
Super resolution optical projection tomography
Gene coding fluorescent probe and its applications
Quantitative and highly-sensitive optical imaging technology for small animals
Theory and method of quantitative optical imaging for specific gastric cancer
Quantification software of dynamic fluorescence/radioluminescence imaging
highly-sensitive weak signal detection techniques for optical imaging
Multimodality, multifunctional molecular imaging probes and their applications
In vivo quantitative visualization of tumor hypoxia
Intelligent nano-drug delivery system and in vivo quantitative visualization technology
Translational study of multimodal optical imaging for detection of cancers




Research
In recent years, Prof. Chen focuses mainly on the development of multiscale, quantitative optical imaging technology at micro to macro scale from cell-animal-human level. The ultimate goal is to provide solutions to early detection and accurate diagnosis of cancers. The research contents include the theoretical methods, imaging systems, and biomedical applications, which have been linked together as the main research lines. Prof. Chen has been supported by the National Key R&D projects, the Major R&D Instruments projects of the NSFC, the Fok Ying-Tong Education Foundation of China, and so on. The total research fund reached 16 million RMB.

On-going Projects:
PI, General Program of the National Natural Science Foundation of China under Grant No. **, Limited-angle and sparse sampling-based Raman-optical projection tomography, 2019.01.01-2022.12.31, 0.57 million.
PI, Subproject of the National Key R&D Program of China under Grant No. 2018YFC**, Research and development of high spatiotemporal resolution, high sensitivity, multi-scale, and multimodality molecular imaging technology for precise diagnosis and treatment of esophageal cancer, 2018.07.01-2020.12.31, 2.8845 million.
Co-PI, Secondary Subproject of the National Key R&D Program of China under Grant No. 2018YFC**, Development of molecular imaging probe with high specificity and high biosafety for esophageal cancer, 2018.07.01-2020.12.31, 0.9615 million.
PI, Youth Teacher Fund of Fok-Ying Tong Education Foundation of China under Grant No. 11604, Signal enhancement and three-dimensional reconstruction for endoscopic Cerenkov luminescence imaging, 2018.03-2021.03, 0.174 million.
PI, The Youth Talent Support Program in Shaanxi Province, Multi-scale, multimodality biophotonics imaging, 2018.01.01-2020.12.31, 1 million
PI, Subproject of Major Scientific Research Instrument Development Project of National Natural Science Foundation of China under Grant No. **, The development and clinical application of multimodality digestive endoscopy, 2017.01.01-2021.12.31, 2.2 million.

Recently Completed Projects:
PI, The Research Fund for Young Star of Science and Technology in Shaanxi Province under Grant No. 2018KJXX-018, Endoscopic radioluminescence imaging technology and 3D imaging method, 2018.01.01-2019.12.31, 0.1 million.
PI, The Best Funded Projects for the Scientific and Technological Activities for Excellent Overseas Researchers in Shaanxi Province under Grant No. **, Bessel beam based spontaneous Raman projection tomography, 2018.01.01-2019.12.31, 0.05 million.
PI, General Program of National Natural Science Foundation of China under Grant No. **, Three-dimensional quantification of tumor receptor by using multimodality imaging of radioluminescence-PET-CT, 2016.01.01-2019.12.31, 0.56 million.
PI, Natural Science Basic Research Plan in Shaanxi Province of China under Grant No. 2015JQ6249, Research on endoscopic Cerenkov luminescence tomographic method and signal enhanced techniques, 2015.01.01-2016.12.31, 0.02 million.
PI, Youth Program of the National Natural Science Foundation of China under Grant No. **, Endoscopic tomography for Cerenkov luminescence imaging, 2012.01.01- 2014.12.31, 0.23 million.
PI, Open Project Program of the State Key Laboratory of Management and Control for Complex System in CAS under Grant No. **, Development of the Endoscopic Cerenkov luminescence imaging system, 2012.12.01-2014.12.31, 0.06 million
PI, Fundamental Research Funds for the Central Universities (JB171202, JBG151206, NSIY061406, K).
Participant, Key Program of National Natural Science Foundation of China under Grant No. U**, Study on the key issues of surgery-assisted system for complex congenital heart diseases surgery with multimodality images fusion and visualization technology, 2015.01.01-2018.12.21, 0.968 million.
Participant, Subproject of Major Scientific Research Instrument Development Project of National Natural Science Foundation of China under Grant No. **, Development of the optical-PET-CT multimodality imaging system, 2013.01.01-2017.12.31, 10 million (2 million).
Participant, Key Program of National Natural Science Foundation of China under Grant No. **, Study of the key point in developing multimodal Radionuclide-Cerenkov fusion imaging, 2013.01.01-2017.12.31, 2.8 million.
Participant, Subproject of the Major Program of the National Natural Science Foundation of China under Grant No. **, 2011.01.01-2014.12.31, 2.01 million (0.5 million).
Participant, Subproject of the Program of the National Basic Research and Development Program of China (973) under Grant No. 2011CB707702, Platform for multimodality image fusion and computing, 2011.01.01-2015.12.31, 0.93 million (0.2 million).
Participant, National Natural Science Foundation of China under Grant Nos., **, **, etc. during years of 2009-2012.




Publications
The current research accomplishments: 76 peer-reviewed journal publications, including 50 first and corresponding author publications, and 2 book chapters.

Book chapters
Xueli Chen, Dongmei Chen, Fenglin Liu, Wenxiang Cong, Ge Wang, and Jimin Liang*. Optical-CT Imaging (Chapter 11), Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications (Editors: George C. Kagadis, Nancy L. Ford, Dimitrios Karnabatidis, and George K. Loudos), Taylors & Francis Inc, 11/03/2016
Jie Tian, Jimin Liang, Xueli Chen, and Xiaochao Qu. Molecular Optical Simulation Environment (Chapter 2), Molecular Imaging: Fundamentals and Applications (Editor: Jie Tian), Zhejiang University Press and Springer-Verlag, 15-46, 2012.

First & Corresponding author peer-reviewed papers
Xueli Chen#,*, Xinyu Wang#, Lin Wang#, Peng Lin, Yonghua Zhan, and Ji-Xin Cheng, “Stimulated Raman scattering signal generation in scattering medium using self-reconstructing Bessel beams,” Photonics Research 2020, in press.
Xueli Chen#,*, Shouping Zhu#, Huiyuan Wang, Cuiping Bao, Defu Yang, Chi Zhang, Peng Lin, Ji-Xin Cheng, Yonghua Zhan, Jimin Liang, and Jie Tian, “Accelerated stimulated Raman projection tomography by sparse reconstruction from sparse-view data,” IEEE Transactions on Biomedical Engineering 2020. DOI: 10.1109/TBME.2019.**
Yunpeng Dai#, Duofang Chen#, Guodong Wang, Jipeng Yin, Yonghua Zhan*, Kaichun Wu, Jimin Liang, and Xueli Chen*, “Kinetic modeling and analysis of dynamic bioluminescence imaging of substrates administered by intraperitoneal injection,” Quantitative Imaging in Medicine and Surgery 2020, in press. DOI: 10.21037/qims.2020.01.01
Duofang Chen, Shouping Zhu, Yi Huang, Jimin Liang, and Xueli Chen*, “Removal of random-valued impulse noise from Cerenkov luminescence images,” Medical & Biological Engineering & Computing 2020. DOI: 10.1007/s11517-019-02069-9. Nov. 21, 2019
Yunpeng Dai#, Guodong Wang#, Duofang Chen, Jipeng Yin, Yonghua Zhan, Yongzhan Nie, Kaichun Wu, Jimin Liang*, and Xueli Chen*, “Intravenous administration-oriented pharmacokinetic model for dynamic bioluminescence imaging,” IEEE Transactions on Biomedical Engineering 2019, 66(3), 843-847. DOI: 10.1109/TBME.2018.** Mar. 2019
Ke Li#, Wenhua Zhan#, Yulong Chen, Rajiv Kumar Jha*, and Xueli Chen*, “Docetaxel and doxorubicin codelivery by nanocarriers for synergistic treatment of prostate cancer,” Frontiers in Pharmacology 2019, 10, 1436. DOI: 10.3389/fphar.2019.01436
Tianyu Yan#, Qi Zeng#, Lin Wang, Nan Wang, Honghao Cao, Xinyi Xu, and Xueli Chen*, “Harnessing the power of optical microscopic and macroscopic imaging for natural products as cancer therapeutics,” Frontiers in Pharmacology 2019, 10, 1438. DOI: 10.3389/fphar.2019.01438
Nan Wang#, Honghao Cao#, Lin Wang, Feng Ren, Qi Zeng, Xinyi Xu, Jimin Liang, Yonghua Zhan, and Xueli Chen*, “Recent advances in spontaneous Raman spectroscopic imaging: instrumentation and applications,” Current Medicinal Chemistry 2019, 26, 1-19. DOI: 10.2174/6**1
Hui Xie#, Huiyuan Wang#, Lin Wang, Nan Wang, Jimin Liang, Yonghua Zhan, and Xueli Chen*, “Comparative studies of total-variation-regularized sparse reconstruction algorithms in projection tomography,” AIP Advances 2019, 9, 085122. Aug. 23, 2019. DOI: 10.1063/1.**
Lin Wang, Honghao Cao, Xin Cao, Shenghan Ren, Ke Li, Yonghua Zhan, Xueli Chen*, and Xiaowei He*, “Adaptively hybrid 3rd simplified spherical harmonics with diffusion equation based multispectral Cerenkov luminescence tomography,” IEEE Access 2019, 7, 160779. DOI: 10.1109/ACCESS.2019.**
Nan Wang#, Duofang Chen#, Dan Chen, Cuiping Bao, Jimin Liang, Xueli Chen*, and Shouping Zhu*, “Feasibility study of limited-angle reconstruction for in vivo optical projection tomography based on novel sample fixation,” IEEE Access 2019, 7(1), 87681-87691. DOI:10.1109/ACCESS.2019.**
Xinyi Xu#, Hanrui Li#, Ke Li, Qi Zeng, Yin Liu, Yun Zeng, Dan Chen, Jimin Liang, Xueli Chen*, and Yonghua Zhan*, “A photo-triggered conjugation approach for attaching RGD ligands to biodegradable mesoporous silica nanoparticles for the tumor fluorescent imaging,” Nanomedicine: Nanotechnology, Biology, and Medicine 2019, 19, 136-144. June 2019
Yunpeng Dai#, Xueli Chen#,*, Jipeng Yin#, Guodong Wang, Bo Wang, Yonghua Zhan*, Yongzhan Nie, Kaichun Wu, and Jimin Liang*, “Investigation of the influence of sampling schemes on quantitative dynamic fluorescence imaging,” Biomedical Optics Express 2018, 9(4), 1859-1870. Mar. 26, 2018.
Defu Yang, Lin Wang, Dongmei Chen, Chenggang Yan, Xiaowei He, Jimin Liang, and Xueli Chen*, “Filtered maximum likelihood expectation maximization based global reconstruction for bioluminescence tomography,” Medical & Biological Engineering & Computing 2018, 56, 2067-2081. (2nd affiliation) Oct. 2018
Lin Wang, Shenghan Ren, and Xueli Chen*, “Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging,” Journal of Innovative Optical Health Sciences 2018, 11(1), **. DOI: 10.1142/S**00171 (2nd affiliation) Nov. 2017
Yun Zeng#, Jingwen Ma#, Yonghua Zhan, Xinyi Xu, Qi Zeng, Jimin Liang*, and Xueli Chen*, “Hypoxia-activated prodrugs and redox-responsive nanocarriers,” International Journal of Nanomedicine 2018, 13, 6551-6574. Oct. 2018
Defu Yang, Chenggang Yan*, Lei Yang, Dongliang Peng, and Xueli Chen*, “An alternative reconstruction framework with optimal permission source region for bioluminescence tomography,” Optics Communications 2018, 427(11), 112-122. (2nd affiliation) June 2018
Lin Wang#, Xin Cao#,*, Xu Cao, Fei Kang, Yonghua Zhan, Xiaowei He, Jing Wang*, and Xueli Chen*,“Feasibility study of radioluminescence film imaging: an optical way to detect medical radionuclides,” Optoelectronics and Advanced Materials-Rapid Communications 2018, 12(9-10), 542-546. (2nd affiliation) Sep.-Oct. 2018
Hanrui Li#, Ke Li#, Yunpeng Dai, Xinyi Xu, Xu Cao, Qi Zeng, Huyulong He, Liaojun Pang, Jimin Liang, Xueli Chen*, and Yonghua Zhan*,“In vivo near infrared fluorescence imaging and dynamic quantification of pancreatic metastatic tumors using folic acid conjugated biodegradable mesoporous silica nanoparticles,” Nanomedicine: Nanotechnology, Biology, and Medicine 2018, 14(6), 1867-1877. Jul. 2018
Lin Wang, Xin Cao, Qingyun Ren, Xueli Chen*, Xiaowei He*,“Hybrid model based unified scheme for endoscopic Cerenkov and radio-luminescence tomography: simulation demonstration,” Journal of Applied Physics 2018, 123(18), 184701. (2nd aff.) May 2018
Xueli Chen#, Chi Zhang#, Peng Lin, Kai-Chih Huang, Jimin Liang, Jie Tian, and Ji-Xin Cheng*, “Volumetric chemical imaging by stimulated Raman projection microscopy and tomography,” Nature Communications 2017, 8, 15117.Apr. 24, 2017. DOI: 10.1038/ncomms15117
Yonghua Zhan#, Wenhua Zhan#, Hanrui Li, Xinyi Xu, Xu Cao, Shouping Zhu, Jimin Liang, and Xueli Chen*, “In vivo dual-modality fluorescence and magnetic resonance imaging-guided lymph node mapping with good biocompatibility manganese oxide nanoparticles,” Molecules 2017, 22(12), 2208. Dec. 2017.
Defu Yang, Xueli Chen*, Chunhui Zhang, Lu Wang, Fanzhen Meng, Qingguo Xie, and Jimin Liang, “Cerenkov luminescence imaging guided selective-reconstruction for a flexible dual-head PET,” Journal of Instrumentation 2017, 12(4), P04005. Apr. 2017
Lin Wang#, Yonghua Zhan#, Defu Yang, and Xueli Chen*, “Specific modeling of light propagation in live body with coupled SP3-radiosity-diffusion equation,” Journal of Medical Imaging and Health Informatics 2017, 7(4), 820-832. Aug. 2017
Xin Cao#, Yonghua Zhan#, Xu Cao, Jimin Liang, and Xueli Chen*, “Harnessing the power of Cerenkov luminescence imaging for gastroenterology: Cerenkov luminescence endoscopy,” Current Medical Imaging Reviews 2017, 13(1), 50-57. Apr. 2017
Yonghua Zhan#, Xu Cao#, Xin Cao, Yingchao Li, Jie Tian, Jimin Liang*, and Xueli Chen*, “Silica Cross-Linked Micellar Core-Shell Nanoparticles Encapsulating IR-780 with Strong Bright and Good Biocompatibility for Optical Imaging In Vivo,” Journal of Biomedical Nanotechnology 2017, 13(2), 144-154. Apr. 2017. DOI: 10.1166/jbn.2016.2332
Yonghua Zhan#, Xu Cao#, Yingchao Li, Xueli Chen*, and Xiaofeng Huang*, “Synthesis and biological evaluation of a novel apogossypolone derivative,” Letters in Drug Design & Discovery 2017, 14(1), 96-101. Apr. 2017DOI: 10.2174/**66**5
Xueli Chen#, Defu Yang#, Fangfang Sun, Xu Cao, and Jimin Liang*, “Adaptively alternative light-transport-model-based three-dimensional optical imaging for longitudinal and quantitative monitoring of gastric cancer in live animal,” IEEE Transactions on Biomedical Engineering 2016, 63(10), 2095-2107. Oct. 1, 2016. DOI: 10.1109/TBME.2015.**
Yonghua Zhan#, Xu Cao#, Xin Cao, Fei Kang, Jing Wang, Jimin Liang, Zhimin Li*, and Xueli Chen*, “Simultaneous multimodality molecular imaging with neodymium-doped Y3Al3O12 nanoparticles,” Optoelectronics and Advanced Materials-Rapid Communications 2016, 10(9-10), 685-688. Sep.-Oct. 2016
Yunpeng Dai, Xueli Chen*, Jipeng Yin, Xiaoyu Kang, Guodong Wang, Xianghan Zhang, Yongzhan Nie, Kaichun Wu, and Jimin Liang*, “Investigation of injection dose and camera integration time on quantifying pharmacokinetics of a Cy5.5-GX1 probe with dynamic fluorescence imaging in vivo,” Journal of Biomedical Optics 2016, 21(8), 086001. DOI: 10.1117/1.JBO.21.8.086001 Sep. 2016
Yunpeng Dai, Jipeng Yin, Yu Huang, Xueli Chen*, Guodong Wang, Yajun Liu, Xianghan Zhang, Yongzhan Nie, Kaichun Wu, and Jimin Liang*, “In vivo quantifying molecular specificity of Cy5.5-labeled cyclic 9-mer peptide probe with dynamic fluorescence imaging,” Biomedical Optics Express 2016, 7(4), 1149-1159. DOI: 10.1364/BOE.7.001149 Apr. 2016
Xueli Chen*, Fangfang Sun, Defu Yang, and Jimin Liang, “Coupled third-order simplified spherical harmonics and diffusion equation-based fluorescence tomographic imaging of liver cancer,” Journal of Biomedical Optics 2015, 20(9), 090502. Sep. 21, 2015. DOI: 10.1117/1.JBO.20.9.090502
Xueli Chen*, Fangfang Sun, Defu Yang, Shenghan Ren, Qian Zhang, and Jimin Liang*, “Hybrid simplified spherical harmonics with diffusion equation for light propagation in tissues,” Physics in Medicine and Biology 2015, 60(16), 6305-6322. Aug. 3, 2015
Xin Cao#, Xueli Chen#, Fei Kang#, Yonghua Zhan, Xu Cao, Jing Wang*, Jimin Liang*, and Jie Tian*, “Intensity enhanced Cerenkov luminescence imaging using terbium-doped Gd2O2S microparticles,”ACS Applied Materials & Interfaces 2015, 7(22), 11775-11782. Jun 10, 2015. DOI: 10.1021/acsami.5b00432.
Defu Yang, Xueli Chen*, Xu, Cao, Jing Wang, Jimin Liang, and Jie Tian, “Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals,” Medical & Biological Engineering & Computing 2015, 53(9), 805-814. DOI: 10.1007/s11517-015-1293-8 Sep. 2015
Xin Cao, Xueli Chen*, Fei Kang, Xu Cao, Yonghua Zhan, Jing Wang, Kaichun Wu, and Jimin Liang*, “Sensitivity improvement of Cerenkov luminescence endoscope with terbium doped Gd2O­2S nanoparticles,” Applied Physics Letters 2015, 106(21), 213702. DOI: 10.1063/1.** May 2015
Hao Hu#, Xin Cao#, Fei Kang#, Min Wang, Yenan Lin, Muhan Liu, Shujun Li, Liping Yao, Jie Liang, Jimin Liang, Yongzhan Nie, Xueli Chen*, Jing Wang*, Kaichun Wu*, “Feasibility study of novel endoscopic Cerenkov luminescence imaging system in detecting and quantifying gastrointestinal disease: first human results,” European Radiology 2015, 25(6), 1814-1822. (2ndaffiliation) May 2015. DOI: 10.1007/s00330-014-3574-2
Xin Cao#, Xueli Chen#, Fei Kang#, Yenan Lin, Muhan Liu, Hao Hu, Yongzhan Nie, Kaichun Wu, Jing Wang*, Jimin Liang*, and Jie Tian*, “Performance evaluation of endoscopic Cerenkov luminescence imaging system: in vitro and pseudotumor studies,” Biomedical Optics Express 2014, 5(10), 3660-3670. Oct. 1, 2014. DOI:10.1364/BOE.5.003660
Xueli Chen*, Defu Yang, Qitan Zhang, and Jimin Liang*, “L1/2 regularization based numerical method for effective reconstruction of bioluminescence tomography,” Journal of Applied Physics 2014, 115(18), 184702. May 14, 2014. DOI: 10.1063/1.**
Xueli Chen*, Qitan Zhang, Defu Yang, and Jimin Liang*, “Hybrid radiosity-SP3 equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions,” Journal of Applied Physics 2014, 115(2), 024702. Jan 14, 2014. DOI: 10.1063/1.**
Defu Yang#, Xueli Chen#, Zhen Peng, Xiaorui Wang, Jorge Ripoll, Jing Wang, and Jimin Liang*, “Light transport in turbid media with non-scattering, low-scattering and high absorption heterogeneities based on hybrid simplified spherical harmonics with radiosity model,” Biomedical Optics Express 2013, 4(10), 2209-2223. Oct. 1, 2013
Xueli Chen*, Jimin Liang, Xin Cao, Defu Yang, Dongmei Chen, Jorge Ripoll, and Jie Tian*, “Feasibility study of endoscopic X-ray luminescence computed tomography: simulation demonstration and phantom application,” Journal of Applied Physics 2013, 114(8), 084701. Aug 28, 2013. DOI: 10.1063/1.**
Xueli Chen#, Defu Yang#, Xiaochao Qu, Hao Hu, Jimin Liang*, Xinbo Gao, and Jie Tian*, “Comparisons of hybrid radiosity-diffusion model and diffusion equation for bioluminescence tomography in cavity cancer detection,” Journal of Biomedical Optics 2012, 17(6), 066015. Jun. 5, 2012. DOI: 10.1117/1.JBO.17.6.066015
Zhenhua Hu#, Xueli Chen#, Jimin Liang*, Xiaochao Qu, Duofang Chen, Weidong Yang, Jing Wang, Feng Cao, and Jie Tian*, “Single photon emission computed tomography- guided Cerenkov luminescence tomography,” Journal of Applied Physics 2012, 112(2), 024703. Jul. 25, 2012. DOI: 10.1063/1.**
Qitan Zhang#, Xueli Chen#, Xiaochao Qu, Jimin Liang*, and Jie Tian*, “Comparative studies of lp-regularization-based reconstruction algorithms for bioluminescence tomography,” Biomedical Optics Express 2012, 3(11), 2816-2836. Nov. 1, 2012
Xueli Chen, Jimin Liang*, Xiaochao Qu, Yanbin Hou, Shouping Zhu, Duofang Chen, Xinbo Gao, and Jie Tian*, “Mapping of bioluminescent images onto CT volume surface for dual-modality BLT and CT imaging,” Journal of X-ray Science and Technology2012, 20(1), 31-44. Apr. 1, 2012. DOI 10.3233/XST-2012-0317
Xueli Chen, Jimin Liang*, Heng Zhao, Xiaochao Qu, Duofang Chen, Qitan Zhang, Xinbo Gao, and Jie Tain*, “Modeling and reconstruction of optical tomography for endoscopic applications: simulation demonstration,” Applied Physics Letters 2011, 99(7), 073702. Aug. 16, 2011. DOI:10.1063/1.**
Xueli Chen, Xinbo Gao*, Duofang Chen, Xiaopeng Ma, Xiaohui Zhao, Man Shen, Xiangsi Li, Xiaochao Qu, Jimin Liang, Jorge Ripoll, and Jie Tian*, “3D reconstruction of light flux distribution on arbitrary surfaces from 2D multi-photographic images,” Optics Express 2010, 18(19), 19876-19893. Sep. 13, 2010
Xueli Chen, Xinbo Gao*, Xiaochao Qu, Duofang Chen, Xiaopeng Ma, Jimin Liang, and Jie Tian, “Generalized free-space diffuse photon transport model based on the influence analysis of camera lens,” Applied Optics 2010, 49(29), 5654-5664. Oct. 7, 2010
Xueli Chen, Xinbo Gao*, Xiaochao Qu, Jimin Liang, Lin Wang, Da’an Yang, Anikitos Garofalakis, Jorge Ripoll, and Jie Tian*, “A study of photon propagation in free-space based on hybrid radiosity-radiance theorem,” Optics Express 2009, 17(18), 16266- 16280. Aug. 31, 2009




Awards & Honors
2020: Second Prize of Shaanxi Natural Science Award, P.R. China (1st position)
2019: Young Investigator Award of the Nature Conference on Translational Imaging in Partnership with the International Symposium on Molecular Imaging (ISMI 2019).
2019: First Prize of Science & Technology Award in Shaanxi Universities, P.R. China (1st position)
2018: Young Top-notch Talent of Special Support Plan in Shaanxi Province
2018: Youth Teacher Fund of Fok-Ying Tong Education Foundation of China
2018: The Young Star of Science and Technology of Shaanxi Province
2017: Best poster award of 1st Cross-Strait Academic Symposium on Biomed. Frontiers
2015.03-2017.03: been awarded a scholarship under the State Scholarship Fund from CSC to pursue study in the USA as a postdoctoral researcher
2014: Excellent Doctoral Dissertation of Xidian University
2014: Second Prize of Science & Technology Award in Shaanxi Universities, P.R. China (1st position)
2011: First Prize of Science & Technology Award in Shaanxi Universities, P.R. China (6th position)
2011: Travel Award of the World Molecular Imaging Congress 2011 (only 6 in China)
2010: Second award for the Scientific and Technological Advancement of Outstanding Achievement of Scientific Research in University, P.R. China (6th position)
2010~2012: Outstanding Doctoral Degree Funding from Xidian University (40000 CNY/ Year)




BMI Lab
Faculty
CHEN Xueli, Professor (Principal Investigator, Biomedical-photonics & Molecular Imaging Lab)
ZENG Qi, Associate Professor (Extraction, modification and evaluation of therapeutic effect of natural drugs)
CHEN Duofang, Associate Professor (Computational microscopic imaging and quantitative opticla imaing)
XU Xinyi, Assistant Professor (Nano-antibody imaging of gene encoding unnatural amino acids based on optical click method)
XIE Hui, Associate Professor (Microbial drug screening based on OPT and computational microscopic imaging)
Wangting Zhou
Shenghan Ren

Current Members
YAN Tianyu, Ph.D. Student (2019.09~)
WANG Nan, Ph.D. Student (2018.09~)
LI Hanrui, Ph. D. Student (2018.03~)
Cao Honghao, Master Student (2017.09~)
WANG Huiyuan, Master Student (2018.09~)
WANG Xinyu, Master Student (2018.09~)
WANG Haoyu, Master Student (2018.09~)
LIU Yichao, Master Student (2018.09~)
LUO Xixin, Master Student (2018.09~)
REN Feng, Master Student (2018.09~)
ZHENG Yun, Master Student (2019.09~)
FAN Dawei, Master Student (2019.09~)
LUO Yanxia, Master Student (2019.09~)
HAO Wenqing, Master Student (2019.09~)
WANG Zhaohui, Msater Student (2019.09~)

Lab Alumni
YAN Tianyu, Master Student (2017.09~2019.08)
WANG Nan, Master Student (2017.09~2018.08)
BAO Cuiping, Master Student (2015.09~2018.06)
DAI Yunpeng, Ph.D. Student (2013.09~2017.12)
CAO Xin, Ph.d. Student (2013.09~2017.12)
SUN Fangfang, Master Student (2013.09~2015.12)
YANG Defu, Ph.D. Student (2011.09~2015.06)




Group Events
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