西安电子科技大学生命科学技术学院导师教师师资介绍简介-吕锐婵

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吕锐婵，西安电子科技大学教授/博导。洪堡****，陕西省普通高校“青年杰出人才”，“华山****”菁英人才。"生物材料与信息转化BIT"团队负责人，近年来主要从事分子影像纳米探针设计、生物成像及抗癌诊疗，在哈尔滨工程大学获得工学学士（2006-2010）和工学博士学位（2012-2015），并在中航企业工作两年（2010-2012），在美国纽约州立大学ILPB和德国马堡大学的Biophotonik实验室进行了生物光子与发光材料的博士后工作（2015-2017）。主持多项国家自然科学基金和横向项目，国家重点研发计划骨干，并与医院和企业合作推进生物材料、影像探针的临床应用许可。发表SCI论文59篇，引用2200余次，其中第一/通讯作者39篇，含中科院分区一区论文13篇，IF>10论文7篇，封面论文8篇，授权专利6项。现任中国医药生物技术协会造影技术分会委员，获“徐叙瑢发光学优秀青年学术论文奖”、珠海分子影像“青年学子奖”等。
目前主要研究方向：
1、发光材料、生物材料、无机非金属材料的合成、表征、性能优化。2、探针用于生物成像、癌症早诊、术中导航。3、优化算法用于组合化学、生物信息靶点挖掘。 4、疾病检测软硬件。
教育及工作简历：
2016-至今西安电子科技大学，生命科学与技术学院，教授。
2016-2017马堡大学，物理系，“洪堡****”博士后。
2015-2016 纽约州立大学布法罗分校，化学系，博士后；
2012-2015 哈尔滨工程大学，材料科学与技术，工学博士；
2010-2012 中航光电科技股份有限公司，工艺员；
2006-2010 哈尔滨工程大学，化学工程与工艺，工学学士；
学术兼职：
Adv. Mater.、Nano Lett.、ACS Nano、Adv. Sci.、Biomaterials、Chem. Mater.、Chem. Sci.、Nanoscale、Chem. Eng. J. 、Biomater. Sci.、Biomacromolecules、Inorg. Chem.、ACS Biomater. Sci. Eng.、J. Lumin.、Part. Part. Syst. Char.等国际SCI杂志的审稿人。

生物材料信息转化研究室
BIT团队：只做发光这一点；培养理念：每天进步一点点；
团队口号：发光增强精准成像；医工研医佑护健康。

SCI杂志封面

个人简介
吕锐婵教授，博导
洪堡****，陕西省普通高校“青年杰出人才”，华山****“菁英人才”
Email: rclv@xidian.edu.cn
地址：西安电子科技大学南校区G323-1
籍贯：河南孟津；毕业学校：哈尔滨工程大学

简讯
9. 2021-06 生物材料与信息转化BIT团队举办毕业生座谈会，祝福毕业硕士刘军及三名本科生前程似锦。https://news.xidian.edu.cn/info/1399/214989.htm
8. 2021-06-25 News!!! BIT团队（硕士孙松）开发的“糖尿病视网膜病变眼底照片AI检测系统”用于西安市第九人民医院内分泌科，卡帕值0.92。
7. 2021-06-19 参加首届分子医学华山论坛做报告《生物信息挖掘靶点修饰发光材料用于精准影像》。
6. 2021-05-28 参加微纳米会议做报告《发光材料用于疾病诊疗》。
5. 2021-04 与上海交通大学医学院第九人民医院合作，利用稀土纳米晶NaGdF4复合多肽实现对原位舌癌的MRI成像（NIRII灵敏度需进一步加强）。网址：https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c01807
中文宣传网址：https://www.x-mol.com/paper/****/t
4. 2021-04 吕锐婵入选华山系列“菁英教授”；2021年4月，获横向项目（9.1万）；获学校前沿交叉研究院“人才培育项目”资助（14万）；获科研院专著资助项目（5万）。
3. 2021-04.19 BIT参加中国化学会第32届年会，做口头报告《发光材料用于体外检测和活体成像》，王燕兴、林碧、徐丹阳墙报展示。
2. 2021-04BIT课题组在祥峪森林公园春游、烧烤等系列活动。
1. 2021-03News!!! 课题组（吕锐婵、王燕兴、林碧、彭向荣等）利用稀土纳米晶NaYF4复合抗体（采用生物信息挖掘突变靶点）实现对原位肺癌的NIR II精准诊断和初步术中导航，论文发表在Analy. Chem.(中科院一区，影响因子6.8)上（DOI:10.1021/acs.analchem.1c00374）。网址：https://pubs.acs.org/doi/10.1021/acs.analchem.1c00374中文网址：https://www.x-mol.com/news/569300
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22. 2020-12 News!!! 热烈祝贺生物材料与信息转化团队（BIT团队）入选第五届学校“三好三有”研究生导学团队。新闻网址：https://news.xidian.edu.cn/info/2106/211948.htm宣传网址：https://news.xidian.edu.cn/info/2106/212382.htm
21. 2020-11 课题组在探针用于口腔癌早诊方面取得进展。其中林碧论文被Biomaterials Science接收；https://pubs.rsc.org/en/content/articlelanding/2021/bm/d0bm01737王燕兴论文被Journal of Bio-X Research接收。https://journals.lww.com/jbioxresearch/pages/currenttoc.aspx
20. 2020-11 恭喜博士王燕兴、硕士徐丹阳获得感恩中国近现代科学家奖学金（医学药学类专项）！
19. 2020-10 参加“微纳米技术与医疗健康创新大会暨中国微米纳米技术学会第四届微米纳米技术应用创新大会”（2020.10.23-10.26，厦门）；吕锐婵做分会报告“上转换/NIRII纳米探针用于肿瘤诊疗”。林碧、王燕兴“Enhanced luminescence guided synergistic immuno-/photodynamic anticancer therapy”海报展示。
18. 2020-10团队研究成果（硕士杨凡、徐丹阳）发表在Langmuir，并入选为封面。研究了不同波长（655，808，980，1064nm）条件下二维碳化钛材料与稀土复合后光热转化为光动力的过程。
17. 2020-10恭喜团队硕士研究生刘军、徐丹阳获得国家奖学金！https://news.xidian.edu.cn/info/2106/214467.htm
16. 2020-09 祝贺组内2017级（已毕业）硕士研究生杨凡、冯淼、蒋雪的学位论文均获得校优秀硕士学位论文。
15. 2020-09 吕锐婵获学院“党支部书记讲党课”竞赛一等奖，并参加学校组织2020年度“基层党组织书记讲党课”竞赛。
网址：https://mp.weixin.qq.com/s/S9spJKon9pjs5tZq5N0-Ww
14. 2020-09 参加第十九届全国头颈部影像学进展学术研讨会（2020.09.04-2020.09.07,上海）并作大会报告，题目“可降解靶向型荧光纳米探针用于头颈癌精准影像”。
13. 2020-08 吕锐婵Frontier in Nanotechnology客座编辑，主题：Advances in Biophotonics: Luminescent Biomaterials for Sensing and Imaging。（生物光子前沿：荧光生物材料用于传感和成像）。链接：https://www.frontiersin.org/research-topics/15898/advances-in-biophotonics-luminescent-biomaterials-for-sensing-and-imaging
12. 2020-08 课题组（硕士徐丹阳）发表论文在ACS Biomater. Sci. Eng. （DOI:10.1021/acsbiomaterials.0c00984）上。研究了片状黑磷与稀土复合材料用于免疫协同治疗，尤其对其光热/光动力效率进行探讨。
11. 2020-07 特邀综述“离散偶极近似仿真金属调制稀土荧光及应用研究”录用在《发光学报》杂志。链接：http://cjl.lightpublishing.cn/thesisDetails?columnId=**&Fpath=home&index=0&l=zh
10. 2020-06 课题组（硕士冯淼）发表论文在Dalton Transactions上，设计了一种pH响应、可降解的上转换/NIRII探针。
9. 2020-06-01 吕锐婵获得2019~2020年度校级“优秀工会干部”表彰。https://gh.xidian.edu.cn/info/1082/7367.htm
8. 2020-05-22 对成都地区进行高考本科招生宣传，线上进行“2020年普通高校招生政策及院校介绍”系列专题直播。
7. 2020-05-17 吕锐婵在Ltb2020&IDL2020做invited talk。报告题目为“Luminescence modulation of phosphors”。
6. News! 2020-04 课题组发表论文在Chem. Mater. (doi:10.1021/acs.chemmater.0c01031)，并入选封面（林碧/刘军/王燕兴并列一作，吕锐婵通讯）(中科院一区，影响因子10.2)，将DDSCAT用于精确指导发光粉强度，所设计的梭形结构发光粉具有精准的表面金粒子分布，这一结构与跟光敏剂/免疫检查点阻断剂联合用于诊疗以及线粒体标记。链接：https://pubs.acs.org/doi/10.1021/acs.chemmater.0c01031
5. 2020-04 课题组（硕士杨凡）发表论文在ACS Comb. Sci. (DOI: 10.1021/acscombsci.0c00035)上（杨凡第一作者，吕锐婵通讯）（IF3.2），将优化算法与组合化学结合优化发光粉，并将机器学习SVM用于发光粉合成稳定性探测；同时，在实验上也开始将光致发光发光粉与电致发光LED结合。
4. 2020-03 课题组（硕士蒋雪）发表论文在Langmuir (DOI: 10.1021/acs.langmuir.0c00343)（中科院二区，JCR一区），通过不同稀土-光热转化剂的对比，深入探讨了吸收/热/发光/稳定性的关系；并入选为杂志封面。
3. 2020-02 生命科学与技术学院吕锐婵教授给绵阳外国语学校高三学子做高考心理疏导。
2. 2020-02 恭喜课题组与陕西肿瘤医院合作，课题组发表论文Biomaterials Science, 2020,8, 1270-1278（王燕兴博士第一作者，吕锐婵通讯），（中科院二区，JCR一区，IF 6.2）稀土复合叶绿素探针用于肿瘤标记、光动力治疗和手术导航！RSC英国皇家化学会对Biomater.Sci., 2020,8, 1270报道，链接：https://mp.weixin.qq.com/s/UWe2fOrLAjaGXanjmf5ggg
1. 2020-01 BIT实验室做年终总结、反思不足、保持优势，2020不忘初心，砥砺前行，再创佳绩！
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23. 2019-12 发表论文在Journal of luminescence (中科院二区，IF3.0)。论文链接：https://www.sciencedirect.com/science/article/abs/pii/S2220
22. 2019-12 BIT小组吕锐婵“华山****”菁英人才期满，考核“优秀”。
21. 2019-12恭喜课题组获资助“医工交叉”横向项目一项。
20. 2019-12 吕锐婵参加“第一届近红外II区光学分子影像学术研讨会”作邀请报告。
19. 2019-11 吕锐婵参加2019年国际肿瘤与生物标记物大会（西安）做邀请报告，并任大会委员。
18. 2019-11 吕锐婵、王燕兴参加Phosphor Safari 2019会议，吕锐婵作invited talk邀请报告。
17. 2019-10-28 BIT实验室组织组内终南山团建活动。
16. 2019-10-18 吕锐婵当选为中国医药生物技术协会造影技术分会委员。
15. 2019-09-24 祝贺冯淼同学获得2018-2019年度国家奖学金。
14. 2019-09 热烈庆祝“生物材料信息转化”BIT(BiomaterInfor Trans Lab)实验室成立。
13. 2019-09 蒋雪、吕锐婵等发表论文在Biomaterials Science（中科院二区，IF 6.2）, 该篇论文入选期刊封面文章。
论文链接：https://pubs.rsc.org/en/content/articlelanding/2019/bm/c9bm00853e#!divAbstract
12. 2019-09 硕士研究生刘军等发表论文在ACS Biomaterials. Sci. Eng.（中科院二区，IF4.5）上，该篇论文入选期刊封面文章.
论文链接：https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b01112
11. 2019-08 欢迎浙江师范大学李春霞研究员到学院及课题组交流并做报告。
10. 2019-08 吕锐婵参加第15届发光学学术会议任分会主席，作“稀土发光材料的生物成像和诊疗性能”邀请报告，获“第8届徐叙瑢发光学优秀青年学术论文奖”。
9. 2019-08 欢迎南洋理工大学Timothy Tan到学院及课题组交流并作报告。
8. 2019-07 吕锐婵参加国家重点研发计划“纳米专项”中期答辩会议，并作课题二工作汇报。
7. 2019-07 冯淼、吕锐婵等发表论文在ACS Biomaterials. Sci. Eng.（中科院二区，IF 4.5）上，该篇论文入选期刊封面文章。
论文链接：https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00688
6. 2019-06 组内肖历杨硕士研究生毕业，祝前程似锦。
5. 2019-06 组内硕士研究生杨凡等发表论文在RSC Adv.（JCR二区，IF 2.9）上。
论文链接：https://pubs.rsc.org/--/content/articlehtml/2019/ra/c9ra03116b
4. 2019-05 恭喜王燕兴在组内硕博连读。
3. 2019-05 王燕兴、吕锐婵等发表论文在ACS Biomaterials. Sci. Eng.（中科院二区，IF 4.5）上，该篇论文入选期刊封面文章。
论文链接：https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00438
2. 2019-04肖历杨、吕锐婵等发表论文在Inorg. Chem. （中科院二区，IF4.8）上。
论文链接：https://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.9b00667
1. 2019-03 欢迎林碧、代瑞仪、徐丹阳、彭向荣、孙松加入课题组。
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6. 2018-11 冯淼、吕锐婵等发表论文在Inorg. Chem. （JCR一区，IF4.8）上。
5. 2018-11 肖历杨、吕锐婵发表论文在ACS Biomaterials. Sci. Eng.（JCR一区，IF4.5）上。
4. 2018-10 吕锐婵、冯淼、Wolfgang J. Parak等发表论文在Nanomaterials（JCR一区，IF3.25）上。
3. 2018-10 吕锐婵、Paras N. Prasad等发表论文在ACS Appl. Bio Mater.（新刊）上。
2. 2018-08 欢迎王燕兴、刘军加入课题组。
1. 2018-08 恭喜吕锐婵获主持国家自然科学基金青年项目。
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2. 2017年12月，吕锐婵获批首届陕西省普通高校“青年杰出人才”，10万。
1. 2017年5月，吕锐婵留学归来，获得西安电子科技大学双一流经费支持，170万。
1. 2016年7月，吕锐婵加入西安电子科技大学生命科学技术学院（教授），并获得华山****菁英人才项目支持，40万。

SCI论文
Year: 2021
(1) Lv, R.; Wang, Y.; Lin, B.; Peng, X.; Liu, J.; Lü, W.-d.; Tian, J. Targeted Luminescent Probes for Precise Upconversion/NIR II Luminescence Diagnosis of Lung Adenocarcinoma. Anal. Chem. 2021, 93 (11), 4984-4992, DOI: 10.1021/acs.analchem.1c00374.https://pubs.acs.org/doi/10.1021/acs.analchem.1c00374
(2) Wu, J.; Liu, J.; Lin, B.; Lv, R.*; Yuan, Y.*; Tao, X*. Met-Targeted Dual-Modal MRI/NIR II Imaging for Specific Recognition of Head and Neck Squamous Cell Carcinoma. Acs Biomater. Sci. Eng. 2021, 7 (4), 1640-1650, DOI: 10.1021/acsbiomaterials.0c01807.
https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c01807
(3) Lin, B.; Wu, J.; Wang, Y.; Sun, S.; Yuan, Y.; Tao, X.; Lv, R. Peptide functionalized upconversion/NIR II luminescent nanoparticles for targeted imaging and therapy of oral squamous cell carcinoma. Biomater. Sci. 2021, 9 (3), 1000-1007, DOI: 10.1039/D0BM01737J.
https://pubs.rsc.org/en/content/articlelanding/2021/bm/d0bm01737
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Year: 2020

(1) Bi Lin，Jun Liu，Yanxing Wang，Fan Yang，Liyu Huang，and RuichanLv*, 2020, Chem. Mater. 2020, 32, 11, 4627–4640.
论文链接：https://pubs.acs.org/doi/10.1021/acs.chemmater.0c01031封面链接：https://pubs.acs.org/toc/cmatex/32/11
(2) Yanxing Wang, Wei-Dong Lü, Bi Lin, Fan Yang, Miao Feng, and Ruichan Lv,* Optimized lanthanide-chlorophyll nanocomposite for dual-modal imaging-guided surgery navigation and anti-cancer theranostics, Biomater. Sci. 2020,8, 1270-1278. 论文链接： https://pubs.rsc.org/en/content/articlelanding/2020/bm/c9bm02057h#!divAbstract封面链接：https://pubs.rsc.org/en/journals/journalissues/bm#!issueid=bm008005&type=current&issnprint=2047-4830
(3）Xue Jiang,Yanxing Wang, Danyang Xu, Bi Lin, Fan Yang, andRuichan Lv,*Lanthanide-based Nanocomposites for Photothermal Therapy under Near Infrared Laser: Relationship between Light and Heat, Bio-stability and Reaction Temperature, Langmuir,2020, 36, 15, 4033–4043. 论文链接：https://pubs.acs.org/doi/10.1021/acs.langmuir.0c00343
（4）Fan Yang，Yanxing Wang，Xue Jiang，Bi Lin，andRuichan Lv,*Optimized Multi-Metal Sensitized Phosphor for Enhanced Red Up-conversion Luminescence by Machine Learning, ACS Comb. Sci., 2020, 22, 5, 285–296. 论文链接：https://pubs.acs.org/doi/10.1021/acscombsci.0c00035
(5） Ruichan Lv*， Fan Yang, Xue Jiang, Bo Hu, Xianghan Zhang, Xueli Chen, Jie Tian, Plasmonic modulated upconversion fluorescence by adjustable distributed gold nanoparticles. J. Lumin. 2020, 116974.论文链接：https://www.sciencedirect.com/science/article/abs/pii/S2220
（6）Miao Feng, Yanxing Wang, Bi Lin, Xiangrong Peng, Ying Yuan, Xiaofeng Tao*and Ruichan Lv*，Degradable pH-responsive NIR-II imaging probes based on a polymer-lanthanide composite for chemotherapy， Dalton Transac.,doi.org/10.1039/D0DT02042G
论文连接：https://pubs.rsc.org/en/content/articlelanding/2020/dt/d0dt02042g/unauth#!divAbstract
（7）吕锐婵*，王燕兴，杨凡，陈朝晖，田捷*，林君*，离散偶极近似仿真金属调制稀土荧光及应用研究，《发光学报》，特邀综述。论文链接：http://cjl.lightpublishing.cn/thesisDetails?columnId=**&Fpath=home&index=0&l=zh
（8）Yanxing Wang，WeidongLü, Ruiyi Dai, Bi Lin, andRuichan Lv*，Lanthanide-semiconductor probes for precise imaging-guided phototherapy and immunotherapy,Journal of Bio-X Research.3(4):193-204. 论文链接：https://journals.lww.com/jbioxresearch/Fulltext/2020/12000/Lanthanide_semiconductor_probes_for_precise.7.aspx
（9）Danyang Xu，Jun Liu，Yanxing Wang，Yingying Jian，Weiwei Wu，andRuichan Lv*，Black Phosphorus Nanosheet with High Thermal Conversion Efficiency for Photodynamic/Photothermal/Immunotherapy，ACS Biomater. Sci. Eng.2020, 6, 9, 4940–4948。论文链接：https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c00984
(10)Danyang Xu, Fan Yang, Danyao Qu, Zhenni Wang, Long Gu, Weiwei Wu*, and Ruichan Lv*, Transferred Photothermal to Photodynamic Therapy Based on the Marriage of Ultrathin Titanium Carbide and Up-Conversion Nanoparticles, Langmuir, DOI: 10.1021/acs.langmuir.0c02521，论文链接：https://pubs.acs.org/doi/10.1021/acs.langmuir.0c02521
_______________________________________________________________________________________________________________________
Year: 2019

(1) Yang, F.; Liu, J.; Jiang, X.; Wu, W.; Wang, Z.; Zeng, Q.; Lv, R.*, Mesoporous semiconductors combined with up-conversion nanoparticles for enhanced photodynamic therapy under near infrared light. RSC Adv. 2019, 9, 17273-17280.
论文链接：https://pubs.rsc.org/--/content/articlehtml/2019/ra/c9ra03116b
(2) Lv, R. *; Xiao, L.; Wang, Y.; Yang, F.; Tian, J. *; Lin, J. *, Searching for the Optimized Luminescent Lanthanide Phosphor Using Heuristic Algorithms. Inorg. Chem. 2019, 58, 6458-6466.
论文链接：https://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.9b00667
(3) Lv, R. *; Wang, Y.; Liu, J.; Feng, M.; Yang, F.; Jiang, X.; Tian, J. *, When a Semiconductor Utilized as an NIR Laser-Responsive Photodynamic/Photothermal Theranostic Agent Integrates with Upconversion Nanoparticles. ACS Biomater. Sci. Eng. 2019, 5, 3100-3110.
论文链接：https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00438
(4) Lv, R. *; Jiang, X.; Yang, F.; Wang, Y.; Feng, M.; Liu, J.; Tian, J. *, Degradable magnetic-response photoacoustic/up-conversion luminescence imaging-guided photodynamic/photothermal antitumor therapy. Biomater. Sci. 2019, 7, 4558-4567.
论文链接：https://pubs.rsc.org/en/content/articlelanding/2019/bm/c9bm00853e#!divAbstract
(5) Lv, R. *; Feng, M.; Liu, J.; Jiang, X.; Yuan, H.; Yan, R.; Tian, J. *, Improved Red Emission and Short-Wavelength Infrared Luminescence under 808 nm Laser for Tumor Theranostics. CS Biomater. Sci. Eng. 2019, 5, 4683-4691.
论文链接：https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00688
(6) Liu, J.; Yang, F.; Feng, M.; Wang, Y.; Peng, X.; Lv, R. *, Surface Plasmonic Enhanced Imaging-Guided Photothermal/Photodynamic Therapy Based on Lanthanide-Metal Nanocomposites under Single 808 nm Laser. ACS Biomater. Sci. Eng.2019, 5, 5051-5059.
论文链接：https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b01112
(7) J Yang, R Xie, L Feng, B Liu, R Lv, C Li, S Gai, F He, P Yang, J Lin, Hyperthermia and Controllable Free Radical Coenhanced Synergistic Therapy in Hypoxia Enabled by Near-Infrared-II Light Irradiation. ACS nano 13 (11), 13144-13160
__________________________________________________________________________________________________
Year: 2018
(1).Lv Ruichan*, Feng Miao,Parak Wolfgang J., Up-Conversion Luminescence Properties of Lanthanide-Gold Hybrid Nanoparticles as Analyzed with Discrete Dipole Approximation. Nanomaterials (Basel, Switzerland), 2018. 8(12).
(2).Feng Miao, Lv Ruichan*, Xiao Liyang, Hu Bo, Zhu Shouping, He Fei, Yang Piaoping*,Tian Jie*, Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy. Inorganic Chemistry, 2018. 57(23): p. 14594-14602.
(3).Lv Ruichan*, Feng Miao, Xiao Liyang, Damasco Jossana A., Tian Jie*,Prasad Paras N.*, Multilevel Nanoarchitecture Exhibiting Biosensing for Cancer Diagnostics by Dual-Modal Switching of Optical and Magnetic Resonance Signals. ACS Applied Bio Materials, 2018. 1(5): p. 1505-1511.
(4).Lv Ruichan*, Xiao Liyang, Jiang Xue, Feng Miao, Yang Fan,Tian Jie*, Optimization of Red Luminescent Intensity in Eu3+-Doped Lanthanide Phosphors Using Genetic Algorithm. ACS Biomaterials Science & Engineering, 2018. 4(12): p. 4378-4384.
(5).Feng Lili, Gai Shili, Dai Yunlu, He Fei, Sun Chunqiang, Yang Piaoping*, Lv Ruichan, Niu Na, An Guanghui,Lin Jun*, Controllable Generation of Free Radicals from Multifunctional Heat-Responsive Nanoplatform for Targeted Cancer Therapy. Chemistry of Materials, 2018. 30(2): p. 526-539.
——————————————————————————————————————————————————
Before 2017
1)Lv Ruichan, Yang Piaoping, Hu Bo, Xu Jiating, Shang Wenting,Tian Jie, In Situ Growth Strategy to Integrate Up-Conversion Nanoparticles with Ultrasmall CuS for Photothermal Theranostics.ACS Nano, 2017. 11(1): p. 1064-1072. (IF13.94)
2) Lv Ruichan, Yang Piaoping, He Fei, Gai Shili, Li Chunxia, Dai Yunlu, Yang Guixin,Lin Jun, A Yolk-like Multifunctional Platform for Multimodal Imaging and Synergistic Therapy Triggered by a Single Near-Infrared Light.ACS Nano, 2015. 9(2): p. 1630-1647. (IF13.94)
3) Lv Ruichan, Yang Dan, Yang Piaoping, Xu Jiating, He Fei, Gai Shili, Li Chunxia, Dai Yunlu, Yang Guixin,Lin Jun, Integration of Upconversion Nanoparticles and Ultrathin Black Phosphorus for Efficient Photodynamic Theranostics under 808 nm Near-Infrared Light Irradiation.Chemistry of Materials, 2016. 28(13): p. 4724-4734. (IF9.47)
4)Lv Ruichan, Yang Piaoping, He Fei, Gai Shili, Yang Guixin, Dai Yunlu, Hou Zhiyao,Lin Jun, An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.Biomaterials, 2015. 63: p. 115-127. (IF8.40)
5)Lv Ruichan, Yang Piaoping, He Fei, Gai Shili, Yang Guixin,Lin Jun, Hollow Structured Y2O3:Yb/Er-CuxS Nanospheres with Controllable Size for Simultaneous Chemo/Photothermal Therapy and Bioimaging.Chemistry of Materials, 2015. 27(2): p. 483-496. (IF9.47)
6)Lv Ruichan, Zhong Chongna, Li Rumin, Yang Piaoping, He Fei, Gai Shili, Hou Zhiyao, Yang Guixin,Lin Jun, Multifunctional Anticancer Platform for Multimodal Imaging and Visible Light Driven Photodynamic/Photothermal Therapy.Chemistry of Materials, 2015. 27(5): p. 1751-1763. (IF9.47)
7)Lv Ruichan, Yang Guixin, He Fei, Dai Yunlu, Gai Shili,Yang Piaoping, LaF3:Ln mesoporous spheres: controllable synthesis, tunable luminescence and application for dual-modal chemo-/photo-thermal therapy.Nanoscale, 2014. 6(24): p. 14799-14809. (IF7.37)
(8)Lv Ruichan, Gai Shili, Dai Yunlu, Niu Na, He Fei,Yang Piaoping, Highly Uniform Hollow GdF3 Spheres: Controllable Synthesis, Tuned Luminescence, and Drug-Release Properties.ACS Applied Materials & Interfaces, 2013. 5(21): p. 10806-10818. (IF7.50)
9)Lv Ruichan, Yang Piaoping, Dai Yunlu, Gai Shili, He Fei,Lin Jun, Lutecium Fluoride Hollow Mesoporous Spheres with Enhanced Up-Conversion Luminescent Bioimaging and Light-Triggered Drug Release by Gold Nanocrystals.ACS Applied Materials & Interfaces, 2014. 6(17): p. 15550-15563. (IF7.50)
10)Lv Ruichan, Gai Shili, Dai Yunlu, He Fei, Niu Na,Yang Piaoping, Surfactant-Free Synthesis, Luminescent Properties, and Drug-Release Properties of LaF3 and LaCO3F Hollow Microspheres.Inorganic Chemistry, 2014. 53(2): p. 998-1008. (IF4.86)
11)Lv Ruichan, Yang Piaoping, Chen Guanying, Gai Shili, Xu Jiating, Paras N. Prasad, Dopamine-mediated photothermal theranostics combined with up-conversion platform under near infrared light.Scientific Reports,2017. 7: 13562 (IF4.26)
12)Lv Ruichan, Wang Depeng, Xiao Liyang, Chen Guanying, Xia Jun, Paras N. Prasad, Stable ICG-loaded upconversion nanoparticles: silica core/shell theranostic nanoplatform for dual-modal upconversion and photoacoustic imaging together with photothermal therapy. Scientific Reports, 2017.DOI: 10.1038/s41598-017-16016-x (IF4.26)
13)Lv Ruichan, Zhong Chongna, Gulzar Arif, Gai Shili, He Fei, Gu Rui, Zhang Shenghuan, Yang Guixin,Yang Piaoping, Synthesis, luminescence, and anti-tumor properties of MgSiO3:Eu-DOX-DPP-RGD hollow microspheres.Dalton Transactions, 2015. 44(42): p. 18585-18595. (IF4.03)
14)Lv Ruichan, Yang Guixin, Dai Yunlu, Gai Shili, He Fei,Yang Piaoping, Self-produced bubble-template synthesis of La2O3:Yb/Er@Au hollow spheres with markedly enhanced luminescence and release properties.Crystengcomm, 2014. 16(41): p. 9612-9621. (IF3.47)
15)Lv Ruichan, Yang Guixin, Gai Shili, Dai Yunlu, He Fei,Yang Piaoping, Multifunctional LaPO4:Ce/Tb@Au mesoporous microspheres: synthesis, luminescence and controllable light triggered drug release.RSC Advances, 2014. 4(108): p. 63425-63435. (IF3.11)
16)Lv Ruichan, Yang Guixin, He Fei, Dai Yunlu, Gai Shili,Yang Piaoping, Mesoporous NaYF4:Yb,Er@Au-Pt(IV)-FA nanospheres for dual-modal imaging and synergistic photothermal/chemo-anti-cancer therapy.RSC Advances, 2015. 5(54): p. 43391-43401.(IF3.11)
17)Lv Ruichan, Zhong Chongna, Gulzar Arif Kuhan, He Fei, Gu Rui, Gai Shili, Zhang Shenghuan, Yang Guixin,Yang Piaoping, Near-infrared light-induced imaging and targeted anti-cancer therapy based on a yolk/shell structure.RSC Advances, 2016. 6(26): p. 21590-21599. (IF3.11)

新增栏目1

荣誉获奖
主持科研项目：
11、专著资助项目（2021）经费：5万； 10. 前沿交叉研究院（2021）经费：14万（50万/3年）；9. 医工交叉项目（2021）经费：4.5w+4.6w ;8. 医工交叉横向项目（2010）经费：10****民币;7、国家自然科学基金青年项目（2018）NSFC**经费：21****民币;6、陕西省普通高校“青年杰出人才支持计划”（2017）经费：10****民币;5、西安电子科技大学双一流经费（2017）经费：170****民币。（已购置：爱丁堡稳态-瞬态荧光仪FLS1000）;4、高校基本科研业务费（2017）JBX181202 经费：10****民币;3、华山****“菁英人才”科研启动金（2016）经费：40****民币;2、高校基本科研业务费（2016）XJS17011 经费：6****民币;1、“洪堡****"奖学金（2016）
参与科研项目：国家重点研发计划纳米专项（骨干）
目前学校任职：
西安电子科技大学生命科学技术学院教授，博导; 生物材料与信息转化BIT团队负责人；学校“智能传感交叉前沿研究”分中心主任；学校留联会理事会委员；生命科学技术学院教授委员会委员；生命科学技术学院学位委员会委员；“生物材料信息转化研究室”主任；“生物医学影像与转化”教师党支部副书记等。

仪器设备
1.1 材料合成实验间（含通风橱、烘箱、离心机、超声清洗机、磁力搅拌器、加热套等）
1.2 细胞房（含超净系统、超净工作台、培养箱、灭菌锅、倒置显微镜等）
2、材料/光谱表征：
扫描电子显微镜（SEM）：美国FEI公司
透射电子显微镜（TEM）: 日本JEOL, JEM 2100
X-射线衍射谱仪（XRD）:德国Bruker；紫外可见近红外分光光度计（UV-vis）：UNICO, UV-3802
瞬态稳态荧光光谱仪（FL）：英国爱丁堡，FLS1000
其他：不同波段激光器。
3、细胞/活体表征：
流式细胞仪：Accuri C6
共聚焦显微镜：日本奥林巴斯，FV3000
莱卡荧光显微镜：日本莱卡，Leica DMI 4000 B
近红外二区小动物成像仪：Grand-Imaging，In-vivo Master
小动物光声成像仪：德国iThera Medical， MSOT inVision 128 PA
能量光散射光谱（EDS）:日本日立，HITACHI SU8220
CT小动物成像仪：匈牙利梅迪索，NanoScan PET/CT
酶标仪：BIOTEK, SYNERGY 2
热成像仪：FLIR

荣誉奖励
13. 校级“三好三有”研究生导学团队（负责人）（2020）
12. 珠海分子影像“青年学子奖”（2020）
11. 校级“优秀工会干部”。（2020）
10. 第8届徐叙瑢发光学优秀青年学术论文奖（2019）
9. 西安电子科技大学第四十一届运动会 100米第一名（教工组）（2019）
8. 西安电子科技大学第四十一届运动会 100米第一名（教工组）（2019）
7. 西安电子科技大学第四十一届运动会4X100米接力团体第二名（教工组）（2019）
6. 西安电子科技大学2018校园迷你马拉松比赛二等奖（教工组）（2018）
5. 本科生招生宣传先进个人（二等奖）（2017）
4. 哈尔滨工程大学优秀博士学位论文（2017）
3. 陕西省普通高校“青年杰出人才”（2017）
2.“洪堡****”（2017）
1. 博士研究生国家奖学金（2015）

Album
album
Our Team-2020 Our Team-2020

Our Team-2020 Our Team-2019

Our Team-2019 Our Team-2018

Team
博士研究生Phd student
2019级 王燕兴（硕博连读，xidianyanxing@163.com；本科太原理工大学，主要方向：稀土发光）
2020级 林碧（硕博连读，xidianlinbi@163.com；本科哈尔滨医科大学，主要方向：靶向诊疗）
硕士研究生Master student
2019级 硕士研究生
彭向荣（本科西电，方向：疾病诊断，生物信息挖掘）
徐丹阳（本科西电，2020年获得国家奖学金，方向：无机非金属用于协同诊疗）
孙松（本科南昌大学，方向：早筛，深度学习）
代瑞仪（本科新乡医学院，方向：稀土发光、淋巴结示踪）
2020级硕士研究生
惠鑫（本科西北农林，方向：多分子成像及检测）
刘正浩（本科西电，方向：体外检测与发光）
马亚群（本科西电，方向：染料探针构建及诊断）
李晨煦（本科西电，方向：磁热诊疗及靶向）
2021级硕士研究生
王展（本科西电保研）李文静（本科西电）王民（本科河南科技大学）

已毕业学生Graduated
已毕业硕士研究生：Graduated
2018级硕士研究生（1个）
刘军（2020年获得国家奖学金）：稀土UCL及NIRII发光调制
2017级硕士研究生（3个）：
Xue JIANG 蒋雪获校优秀硕士学位论文（2020）：近红外稀土上转换用于诊疗
Miao FENG 冯淼获校优秀硕士学位论文（2020）国家奖学金（2019）：稀土高掺杂NIRII发光、可降解体系构建
Fan YANG 杨凡获校优秀硕士学位论文（2020） ;金属调制稀土发光、DDA模拟
2016级硕士研究生（1个）：
Liyang XIAO 肖历杨：启发式算法优化稀土下转换发光（Eu及CeTb）
已毕业本科毕业生：
2017级（3个）：Kaikai LIU刘凯凯; Zhan WANG 王展; Wenjign LI 李文静
2016级（2个）：Huijuan YUAN 袁慧娟; Ruyu YAN 闫如玉
2014级（1个）:Xinyi WANG 王欣怡

课程教学
目前承担的教学任务：
本科生（大一）《线性代数》（32学时）
本科生（大二）《生物材料》（32学时）
本科生（大三）《工程概论》（16学时）
本科生（大三）《计算机科学类课程设计》（8学时）
研究生（研一）《生物医用材料》（48学时）
本科生（大一、大三、大四）《专业教育》（4学时/学年）
本科生（大一）《新生研讨课》（2学时）
本科生（2019级）《导学团队》（16学时/学年）
教改论文：
1、学科交叉融合背景下的实验室安全问题研究，2019，《西北大学学报》
2、前沿交叉学科“课程思政”教学改革实践探索——以《生物医用材料》课为例，2020，《教育教学论坛》

教学视频回放地址
2020 线上教学直播地址：
《线性代数》第一章行列式（**、0226、0304）
1.1 1.2 二/三阶行列式，全排列及对换
1.3 1.4 行列式的定义和性质 http://zhibo.chaoxing.com/** https://zhibo.chaoxing.com/**
1.5 行列式展开及克莱默法则 https://zhibo.chaoxing.com/**
第二章矩阵（**、0318、0325、0401）
2.1 矩阵的概念 https://zhibo.chaoxing.com/**
2.2 矩阵的运算及特殊矩阵https://zhibo.chaoxing.com/**
2.3 逆矩阵https://zhibo.chaoxing.com/**
2.4 分块矩阵https://zhibo.chaoxing.com/**
第三章矩阵和线性方程组（**、0415、0422）
3.1 矩阵的初等变换https://zhibo.chaoxing.com/**
3.2 矩阵的秩https://zhibo.chaoxing.com/**
3.3 线性方程组的解https://zhibo.chaoxing.com/**
第四章向量组的线性关系（** 0506 0513）
4.1 向量组及4.2线性关系https://zhibo.chaoxing.com/**
4.3 向量组的秩及4.4基础解系https://zhibo.chaoxing.com/**
4.5 向量空间及5.1欧式空间https://zhibo.chaoxing.com/**
第五章向量组的线性关系（2020 0603）
5.2 特征值和特征向量 5.3 相似矩阵
5.4 对称阵的对角化 5.5 二次型及标准型（正交转化和5.6配方法）
5.7 正定二次型

招生要求
招生专业：
1、博士研究生招生：生物信息科学与技术
2、硕士研究生招生：（1）学术型 077700 生物医学工程（包含：生物材料与细胞工程）
（2）学术型 083100生物医学工程
（3）专业学位型： 085600 材料与化工
——————————————————————————————————————————
（已结束）
欢迎2020级硕士研究生加入，BIT课题组每年有3-5个硕士名额，在今年的硕士生队伍补充中，我们欢迎以下方向：
1、化学/材料类 2、生物技术/医学工程类 3、光学工程类
感兴趣的学生请Email: rclv@xidian.edu.cn
报考代码：学术型：生物医学工程（077700方向/083100方向二）；专业学位型：电子信息（085400）
目前主要研究方向：
1、算法指导组合化学。2、纳米科技与生物成像。3、生物光子和抗癌诊疗。
每年有2-4名硕士研究生名额，欢迎化学、物理、材料、生物及交叉方向的学生报考。
有意者联系 rclv@xidian.edu.cn

Profile
2016- Professor
School of life science and technology, Xidian University
2016-2017 Humboldt fellowship
Faculty of Physics, Philipps University of Marburg, (Host: Wolfgang J. Parak)
2015-2016 Postdoctoral Associate
Department of Chemistry, University at Buffalo, SUNY (Host: Paras N. Prasad)
2012 – 2015 Ph. D.
College of Material Science and Chemical Engineering,
Harbin Engineering University, (Supervisor: Piaoping Yang)
2010 –2012 Engineer
China Aviation Optical-Electrical Technology Co, Ltd
2006 –2010 B. S. (Chemical Engineering and Technology)
College of Material Science and Chemical Engineering, Harbin Engineering University
Being reviewer ofSCI journals including:Adv. Mater.、Nano Lett.、ACS Nano、Adv. Sci.、Biomaterials、Chem. Mater.、Chem. Eng. J. 、Biomater. Sci.、Biomacromolecules、Inorg. Chem.、ACS Biomater. Sci. Eng.、J. Lumin.、Part. Part. Syst. Char.、RSC Adv.、Appl. Organomet. Chem.、Mater. Chem. Phys.
My research interest is focused on Biomaterials, Bioimaging, and Cancer Theranostics:
1. Algorithm-guided optimization of various micro/nano- imaging probes.
2. Rare earth luminescent materials and their applications in bio-imaging, early diagnosis, and surgery navigation.
3. The multi-modal imaging properties of up-conversion luminescence, short-wavelength near-infrared, etc..
4. The multi-modal imaging-guided synergistic anti-cancer therapy platform.

Update
Year: 2020
News!2020-05课题组论文Chem. Mater. (doi:10.1021/acs.chemmater.0c01031)入选为杂志封面！
8. News! 2020-04 课题组发表论文在Chem. Mater. (doi:10.1021/acs.chemmater.0c01031)上，（林碧/刘军/王燕兴并列一作，吕锐婵通讯）(中科院一区，影响因子10.2)，将DDSCAT用于精确指导发光粉强度，所设计的梭形结构发光粉具有精准的表面金粒子分布，这一结构与跟光敏剂/免疫检查点阻断剂联合用于诊疗以及线粒体标记。链接：https://pubs.acs.org/doi/10.1021/acs.chemmater.0c01031
6. 2020-03 A new paper ！课题组发表论文在Langmuir (DOI: 10.1021/acs.langmuir.0c00343)上（蒋雪第一作者，吕锐婵通讯）（中科院二区，JCR一区），通过不同稀土-光热转化剂的对比，深入探讨了吸收/热/发光/稳定性的关系；并入选为杂志封面。链接：https://pubs.acs.org/doi/10.1021/acs.langmuir.0c00343
5. 2020-02 RSC英国皇家化学会对Biomater.Sci., 2020,8, 1270报道，链接：https://mp.weixin.qq.com/s/UWe2fOrLAjaGXanjmf5ggg
4.2020-02 A new paper ！！论文Biomater. Sci. 2020,DOI: 10.1039/C9BM02057H入选为杂志封面front cover。
封面链接：https://pubs.rsc.org/en/journals/journalissues/bm#!issueid=bm008005&type=current&issnprint=2047-4830
3. 2020-02 生命科学与技术学院吕锐婵教授给绵阳外国语学校高三学子做高考心理疏导。
2. 2020-02 A new paper ！！恭喜课题组与陕西肿瘤医院合作，课题组发表论文Biomaterials Science, 2020,8, 1270-1278（王燕兴博士第一作者，吕锐婵通讯），（中科院二区，JCR一区，IF5.25）稀土复合叶绿素探针用于肿瘤标记、光动力治疗和手术导航！
论文链接：http://xlink.rsc.org/?DOI=C9BM02057H
1. 2020-01 BIT实验室做年终总结、反思不足、保持优势，2020不忘初心，砥砺前行，再创佳绩！
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Year: 2019
23. 2019-12A new paper ！！课题组硕士研究生杨凡等发表论文在Journal of luminescence (中科院二区，IF2.96)！
论文链接：https://www.sciencedirect.com/science/article/abs/pii/S2220
22. 2019-12 BIT小组吕锐婵“华山****”菁英人才期满，考核“优秀”！
21. 2019-12恭喜课题组获资助“医工交叉”横向项目一项！
20. 2019-12 吕锐婵参加“第一届近红外II区光学分子影像学术研讨会”作邀请报告。
19. 2019-11 吕锐婵参加2019年国际肿瘤与生物标记物大会（西安）做邀请报告，并任大会委员。
18. 2019-11 吕锐婵、王燕兴参加Phosphor Safari 2019会议，吕锐婵作invited talk邀请报告。
17. 2019-10-28 BIT实验室组织组内终南山团建活动！
16. 2019-10-18 吕锐婵当选为中国医药生物技术协会造影技术分会委员！
15. 2019-09-24 祝贺冯淼同学获得2018-2019年度国家奖学金！
14. 2019-09 热烈庆祝“生物材料信息转化”BIT(BiomaterInfor Trans Lab)实验室成立！
(20).2019.09 A new paper ！！"Degradable magnetic-response photoacoustic/up-conversion luminescence imaging-guided photodynamic/photothermal antitumor therapy" published in Biomaterials Science. by authors: Ruichan Lv,* Xue Jiang, Fan Yang, Yanxing Wang, Miao Feng, Jun Liu, and Jie Tian*.DOI: ?10.1039?/C9BM00853E
(19).2019.08A new paper ！！"Surface Plasmonic Enhanced Imaging-Guided Photothermal/ Photodynamic Therapy Based on Lanthanide-Metal Nanocomposite Under Single 808 nm Laser" published in ACS Biomaterials Sicence & Engineering. by authors:Jun Liu; Fan Yang; Miao Feng; Yanxing Wang; Xiangrong Peng; Ruichan Lv*.
and highlighted as the journal cover!!
(18).2019.07 A new paper ！！"Improved Red Emission and Short Wavelength Infraed Luminescence Under 808nm Laser for Tumor Theranostics" published in ACS Biomaterials Sicence & Engineering. by authors: Lv, Ruichan*; Feng, Miao; Liu, Jun; Jiang Xue; Yuan, Huijuan; Yan Ruyu; Tian, Jie*.
and highlighted as the journal cover!!
(17) 2019.06 “Mesoporous semiconductors combined with up-conversion nanoparticles for enhanced photodynamic therapy under near infrared light”.published in"Rsc Adv.", 2019. 9(30): p. 17273-17280. by authors:.Yang Fan, Liu Jun, Jiang Xue, Wu Weiwei, Wang Zhenni, Zeng Qi, Lv Ruichan*.
(16) 2019.05 A new paper ！！“When the Semiconductor Utilized as the NIR Laser-Responsive Photodynamic/ Photothermal Theranostic Agent Integrated with Upconversion Nanoparticles” published in ACS Biomaterials Sicence & Engineering” (IF: 4.4). by Author(s): Lv Ruichan, Wang Yanxing, Liu Jun, Feng Miao, Yang Fan, Jiang Xue, Tian Jie . DOI: 10.1021/acsbiomaterials.9b00438
and highlighted as the journal cover!!
(15) 2019.04 A new paper ！！“Searching for the Optimized Luminescent Lanthanide Phosphor Using Heuristic Algorithms” published in “Inorg. Chem." (IF: 4.7). by Author(s): Lv Ruichan*, Xiao Liyang, Wang Yanxing, Yang Fan, Tian Jie*, Lin Jun*. DOI: 10.1021/acs.inorgchem.9b00667
2019-04-10 Welcome our fresh graduate students: Lin Bi, Dai Ruiyi, Xu Danyang, Peng Xiangrong, Sun Song!!
(14) 2018.11 A new paper ！！“Up-Conversion Luminescence Properties of Lanthanide-Gold Hybrid Nanoparticles as Analyzed with Discrete Dipole Approximation” published in “Nanomaterials” (IF:3.5). by Author(s): Lv Ruichan*, Feng Miao, Wolfgang J. Parak. DOI: 10.3390/nano**
(13) 2018.11 A new paper ！！“Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy” published in “Inorganic Chemistry” (IF:4.7). by Author(s): Feng Miao, Lv Ruichan*, Xiao Liyang, Hu Bo, Zhu Shouping, He Fei, Yang Piaoping*, Tian Jie*.DOI:10.1021/acs.inorgchem.8b02257
(12) 2018.10 A new paper ！！ “Optimization of Red Luminescent Intensity in Eu³⁺-Doped Lanthanide Phosphors Using Genetic Algorithm” published in “ACS Biomaterials Science & Engineering”(IF:4.43).byLv Ruichan*;Xiao Liyang; Jiang Xue; Feng Miao; Yang Fan; Tian Jie*. DOI: 10.1021/acsbiomaterials.8b00513
(11) 2018.10 A new paper ！！ “A Multilevel Nanoarchitecture Exhibiting Biosensing for Cancer Diagnostic by Dual Modal Switching of Optical and Magnetic Resonance Signals” published in “ACS Applied Bio Materials” by Lv Ruichan*; Feng Miao; Xiao Liyang; Damasco Jossana; Tian Jie*; Prasad Paras*.DOI: 10.1021/acsabm.8b00429
(10) 2017.11 A new paper “Stable ICG-loaded upconversion nanoparticles: silica core/shell theranostic nanoplatform for dual-modal upconversion and photoacoustic imaging together with photothermal therapy” published in “Scientific Reports” (IF: 4.26).Lv Ruichan, Wang Depeng, Xiao Liyang, Chen Guanying, Xia Jun, Paras N. Prasad. 2017. DOI: 10.1038/s41598-017-16016-x
(9) 2017.10 A new paper “Dopamine-mediated photothermal theranostics combined with up-conversion platform under near infrared light” published in “Scientific Reports” (IF: 4.26), Lv Ruichan, Yang Piaoping, Chen Guanying, Gai Shili, Xu Jiating, Paras N. Prasad. 2017. 7: 13562
(8) Oral presentation.2017.05.13 Lv Ruichan participated inthe “2017 Humboldt Kolleg on Smart Materials: From Molecules to Engineering” (Beijing), and made an oral presentation named “Rare Earth Based Mesoprous Materials for Theranostics”.
(7) 2017.05.03 Lv Ruichan finishedthepostdoc work with Prof. Wolfgang J. Parak, and came back to Xidian University.
(6) 2017.02 A new paper!! “In Situ Growth Strategy to Integrate Up-Conversion Nanoparticles with Ultrasmall CuS for Photothermal Theranostics” published in “ACS Nano” (IF: 13.33).2017, 11, (1), 1064-1072.
(5) 2016.10 Lv Ruichan finished the postdoc with Prof. Paras N. Prasad in ILPB (SUNY at buffalo).
(4) (Oral) Highly stable upconversion imaging guided photothermal therapy inspired by transferred dopamine under single NIR light, 8^th annual postdoc research research symposium, Buffalo, June 10, 2016.
(3) (Poster) A Yolk-like Multifunctional Platform for Multimodal Imaging and Synergistic Therapy Triggered by a Single Near-Infrared Light , China Nanomedicine 2015, Hangzhou, April 6-9, 2015.

Philipps-Universität Marburg: Prof. Wolfgang J. Parak
(2) (Poster) Lutecium Fluoride Hollow Mesoporous Spheres with Enhanced Up-Conversion Luminescent Bioimaging and Light-Triggered Drug Release by Gold Nanocrystals, Phosphor Safari 2014, Kunming, November 8-10, 2014.
CIAC researcher: Jun Lin
(1) (Poster) Surfactant-Free Synthesis, Luminescent Properties, and Drug-Release Properties of LaF₃ and LaCO₃F Hollow Microspheres, 29th Annual Seminar Chinese Chemical Society, Beijing, August 4-7, 2014.

Introduction
Ruichan Lv Professor
Humboldt Fellowship
Department: School of life science and technology
Email: rclv@xidian.edu.cn

Research Interests
Biophotonic;
Nanotechnology

Research
目前研究团队承担的科研项目：

Papers
Year: 2020
Journal cover

(1) Bi Lin，Jun Liu，Yanxing Wang，Fan Yang，Liyu Huang，andRuichanLv*, 2020,Chem. Mater.DOI:10.1021/acs.chemmater.0c01031
论文链接：https://pubs.acs.org/doi/10.1021/acs.chemmater.0c01031
(2) Yanxing Wang, Wei-Dong Lü, Bi Lin, Fan Yang, Miao Feng, andRuichan Lv,*Optimized lanthanide-chlorophyll nanocomposite for dual-modal imaging-guided surgery navigation and anti-cancer theranostics,Biomater. Sci.2020,2020,8, 1270-1278.
DOI: 10.1039/C9BM02057H
论文链接：https://pubs.rsc.org/en/content/articlelanding/2020/bm/c9bm02057h#!divAbstract
封面链接：https://pubs.rsc.org/en/journals/journalissues/bm#!issueid=bm008005&type=current&issnprint=2047-4830
（3）Xue Jiang,Yanxing Wang, Danyang Xu, Bi Lin, Fan Yang, andRuichan Lv,*Lanthanide-based Nanocomposites for Photothermal Therapy under Near Infrared Laser: Relationship between Light and Heat, Bio-stability and Reaction Temperature,Langmuir,2020, 36, 15, 4033–4043.
论文链接：https://pubs.acs.org/doi/10.1021/acs.langmuir.0c00343
（4）Fan Yang，Yanxing Wang，Xue Jiang，Bi Lin，andRuichan Lv,*Optimized Multi-Metal Sensitized Phosphor for Enhanced Red Up-conversion Luminescence by Machine Learning,ACS Comb. Sci., 2020, 22, 5, 285–296
论文链接：https://pubs.acs.org/doi/10.1021/acscombsci.0c00035
(5)Lv, R. *; Yang, F.; Jiang, X.; Hu, B.; Zhang, X.; Chen, X.; Tian, J., Plasmonic modulated upconversion fluorescence by adjustable distributed gold nanoparticles. J. Lumin. 2020, 116974.
论文链接：https://www.sciencedirect.com/science/article/abs/pii/S2220
（6）Miao Feng, Yanxing Wang,Bi Lin,Xiangrong Peng, Ying Yuan, Xiaofeng Tao*andRuichan Lv*，Degradable pH-responsive NIR-II imaging probes based on a polymer-lanthanide composite for chemotherapy， Dalton Transac.,doi.org/10.1039/D0DT02042G
论文连接：https://pubs.rsc.org/en/content/articlelanding/2020/dt/d0dt02042g/unauth#!divAbstract
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Year: 2019

(1) Yang, F.; Liu, J.; Jiang, X.; Wu, W.; Wang, Z.; Zeng, Q.; Lv, R.*, Mesoporous semiconductors combined with up-conversion nanoparticles for enhanced photodynamic therapy under near infrared light. RSC Adv. 2019, 9, 17273-17280.
(2) Lv, R. *; Xiao, L.; Wang, Y.; Yang, F.; Tian, J. *; Lin, J. *, Searching for the Optimized Luminescent Lanthanide Phosphor Using Heuristic Algorithms. Inorg. Chem. 2019, 58, 6458-6466.
(3) Lv, R. *; Wang, Y.; Liu, J.; Feng, M.; Yang, F.; Jiang, X.; Tian, J. *, When a Semiconductor Utilized as an NIR Laser-Responsive Photodynamic/Photothermal Theranostic Agent Integrates with Upconversion Nanoparticles. ACS Biomater. Sci. Eng. 2019, 5, 3100-3110.
(4) Lv, R. *; Jiang, X.; Yang, F.; Wang, Y.; Feng, M.; Liu, J.; Tian, J. *, Degradable magnetic-response photoacoustic/up-conversion luminescence imaging-guided photodynamic/photothermal antitumor therapy. Biomater. Sci. 2019, 7, 4558-4567.
https://pubs.rsc.org/en/content/articlelanding/2019/bm/c9bm00853e#!divAbstract
(5) Lv, R. *; Feng, M.; Liu, J.; Jiang, X.; Yuan, H.; Yan, R.; Tian, J. *, Improved Red Emission and Short-Wavelength Infrared Luminescence under 808 nm Laser for Tumor Theranostics. CS Biomater. Sci. Eng. 2019, 5, 4683-4691.
(6) Liu, J.; Yang, F.; Feng, M.; Wang, Y.; Peng, X.; Lv, R. *, Surface Plasmonic Enhanced Imaging-Guided Photothermal/Photodynamic Therapy Based on Lanthanide-Metal Nanocomposites under Single 808 nm Laser. ACS Biomater. Sci. Eng.2019, 5, 5051-5059.
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Year: 2018
(1).Lv Ruichan*, Feng Miao,Parak Wolfgang J., Up-Conversion Luminescence Properties of Lanthanide-Gold Hybrid Nanoparticles as Analyzed with Discrete Dipole Approximation. Nanomaterials (Basel, Switzerland), 2018. 8(12).
(2).Feng Miao, Lv Ruichan*, Xiao Liyang, Hu Bo, Zhu Shouping, He Fei, Yang Piaoping*,Tian Jie*, Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy. Inorganic Chemistry, 2018. 57(23): p. 14594-14602.
(3).Lv Ruichan*, Feng Miao, Xiao Liyang, Damasco Jossana A., Tian Jie*,Prasad Paras N.*, Multilevel Nanoarchitecture Exhibiting Biosensing for Cancer Diagnostics by Dual-Modal Switching of Optical and Magnetic Resonance Signals. ACS Applied Bio Materials, 2018. 1(5): p. 1505-1511.
(4).Lv Ruichan*, Xiao Liyang, Jiang Xue, Feng Miao, Yang Fan,Tian Jie*, Optimization of Red Luminescent Intensity in Eu3+-Doped Lanthanide Phosphors Using Genetic Algorithm. ACS Biomaterials Science & Engineering, 2018. 4(12): p. 4378-4384.
(5).Feng Lili, Gai Shili, Dai Yunlu, He Fei, Sun Chunqiang, Yang Piaoping*, Lv Ruichan, Niu Na, An Guanghui,Lin Jun*, Controllable Generation of Free Radicals from Multifunctional Heat-Responsive Nanoplatform for Targeted Cancer Therapy. Chemistry of Materials, 2018. 30(2): p. 526-539.
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Before 2017
1)Lv Ruichan, Yang Piaoping, Hu Bo, Xu Jiating, Shang Wenting,Tian Jie, In Situ Growth Strategy to Integrate Up-Conversion Nanoparticles with Ultrasmall CuS for Photothermal Theranostics.ACS Nano, 2017. 11(1): p. 1064-1072. (IF13.94)
2) Lv Ruichan, Yang Piaoping, He Fei, Gai Shili, Li Chunxia, Dai Yunlu, Yang Guixin,Lin Jun, A Yolk-like Multifunctional Platform for Multimodal Imaging and Synergistic Therapy Triggered by a Single Near-Infrared Light.ACS Nano, 2015. 9(2): p. 1630-1647. (IF13.94)
3) Lv Ruichan, Yang Dan, Yang Piaoping, Xu Jiating, He Fei, Gai Shili, Li Chunxia, Dai Yunlu, Yang Guixin,Lin Jun, Integration of Upconversion Nanoparticles and Ultrathin Black Phosphorus for Efficient Photodynamic Theranostics under 808 nm Near-Infrared Light Irradiation.Chemistry of Materials, 2016. 28(13): p. 4724-4734. (IF9.47)
4)Lv Ruichan, Yang Piaoping, He Fei, Gai Shili, Yang Guixin, Dai Yunlu, Hou Zhiyao,Lin Jun, An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.Biomaterials, 2015. 63: p. 115-127. (IF8.40)
5)Lv Ruichan, Yang Piaoping, He Fei, Gai Shili, Yang Guixin,Lin Jun, Hollow Structured Y2O3:Yb/Er-CuxS Nanospheres with Controllable Size for Simultaneous Chemo/Photothermal Therapy and Bioimaging.Chemistry of Materials, 2015. 27(2): p. 483-496. (IF9.47)
6)Lv Ruichan, Zhong Chongna, Li Rumin, Yang Piaoping, He Fei, Gai Shili, Hou Zhiyao, Yang Guixin,Lin Jun, Multifunctional Anticancer Platform for Multimodal Imaging and Visible Light Driven Photodynamic/Photothermal Therapy.Chemistry of Materials, 2015. 27(5): p. 1751-1763. (IF9.47)
7)Lv Ruichan, Yang Guixin, He Fei, Dai Yunlu, Gai Shili,Yang Piaoping, LaF3:Ln mesoporous spheres: controllable synthesis, tunable luminescence and application for dual-modal chemo-/photo-thermal therapy.Nanoscale, 2014. 6(24): p. 14799-14809. (IF7.37)
(8)Lv Ruichan, Gai Shili, Dai Yunlu, Niu Na, He Fei,Yang Piaoping, Highly Uniform Hollow GdF3 Spheres: Controllable Synthesis, Tuned Luminescence, and Drug-Release Properties.ACS Applied Materials & Interfaces, 2013. 5(21): p. 10806-10818. (IF7.50)
9)Lv Ruichan, Yang Piaoping, Dai Yunlu, Gai Shili, He Fei,Lin Jun, Lutecium Fluoride Hollow Mesoporous Spheres with Enhanced Up-Conversion Luminescent Bioimaging and Light-Triggered Drug Release by Gold Nanocrystals.ACS Applied Materials & Interfaces, 2014. 6(17): p. 15550-15563. (IF7.50)
10)Lv Ruichan, Gai Shili, Dai Yunlu, He Fei, Niu Na,Yang Piaoping, Surfactant-Free Synthesis, Luminescent Properties, and Drug-Release Properties of LaF3 and LaCO3F Hollow Microspheres.Inorganic Chemistry, 2014. 53(2): p. 998-1008. (IF4.86)
11)Lv Ruichan, Yang Piaoping, Chen Guanying, Gai Shili, Xu Jiating, Paras N. Prasad, Dopamine-mediated photothermal theranostics combined with up-conversion platform under near infrared light.Scientific Reports,2017. 7: 13562 (IF4.26)
12)Lv Ruichan, Wang Depeng, Xiao Liyang, Chen Guanying, Xia Jun, Paras N. Prasad, Stable ICG-loaded upconversion nanoparticles: silica core/shell theranostic nanoplatform for dual-modal upconversion and photoacoustic imaging together with photothermal therapy. Scientific Reports, 2017.DOI: 10.1038/s41598-017-16016-x (IF4.26)
13)Lv Ruichan, Zhong Chongna, Gulzar Arif, Gai Shili, He Fei, Gu Rui, Zhang Shenghuan, Yang Guixin,Yang Piaoping, Synthesis, luminescence, and anti-tumor properties of MgSiO3:Eu-DOX-DPP-RGD hollow microspheres.Dalton Transactions, 2015. 44(42): p. 18585-18595. (IF4.03)
14)Lv Ruichan, Yang Guixin, Dai Yunlu, Gai Shili, He Fei,Yang Piaoping, Self-produced bubble-template synthesis of La2O3:Yb/Er@Au hollow spheres with markedly enhanced luminescence and release properties.Crystengcomm, 2014. 16(41): p. 9612-9621. (IF3.47)
15)Lv Ruichan, Yang Guixin, Gai Shili, Dai Yunlu, He Fei,Yang Piaoping, Multifunctional LaPO4:Ce/Tb@Au mesoporous microspheres: synthesis, luminescence and controllable light triggered drug release.RSC Advances, 2014. 4(108): p. 63425-63435. (IF3.11)
16)Lv Ruichan, Yang Guixin, He Fei, Dai Yunlu, Gai Shili,Yang Piaoping, Mesoporous NaYF4:Yb,Er@Au-Pt(IV)-FA nanospheres for dual-modal imaging and synergistic photothermal/chemo-anti-cancer therapy.RSC Advances, 2015. 5(54): p. 43391-43401.(IF3.11)
17)Lv Ruichan, Zhong Chongna, Gulzar Arif Kuhan, He Fei, Gu Rui, Gai Shili, Zhang Shenghuan, Yang Guixin,Yang Piaoping, Near-infrared light-induced imaging and targeted anti-cancer therapy based on a yolk/shell structure.RSC Advances, 2016. 6(26): p. 21590-21599. (IF3.11)
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(18).Xu Jiating, Kuang Ye, Lv Ruichan, Yang Piaoping, Li Chunxia, Bi Huiting, Liu Bin, Yang Dan, Dai Yunlu, Gai Shili, He Fei, Xing Bengang,Lin Jun, Charge convertibility and near infrared photon co-enhanced cisplatin chemotherapy based on upconversion nanoplatform.Biomaterials, 2017. 130: p. 42-55.
(19).Xu Jie, Li Lei, He Fei, Lv Ruichan,Yang Piaoping, A Novel double-shelled C@NiO hollow microsphere: Synthesis and application for electrochemical capacitor.Electrochimica Acta, 2014. 148: p. 211-219.
(20).Xu Jiating, Lv Ruichan, Du Shaokang, Gai Shili, He Fei, Yang Dan,Yang Piaoping, UCNPs@gelatin-ZnPc nanocomposite: synthesis, imaging and anticancer properties.Journal of Materials Chemistry B, 2016. 4(23): p. 4138-4146.
(21).Xu Jiating, Sun Mingdi, Kuang Ye, Bi Huiting, Liu Bin, Yang Dan, Lv Ruichan, Gai Shili, He Fei,Yang Piaoping, Markedly enhanced up-conversion luminescence by combining IR-808 dye sensitization and core-shell-shell structures.Dalton Transactions, 2017. 46(5): p. 1495-1501.
(22).Xu Jiating, Yang Dan, Lv Ruichan, Liu Bin, Gai Shili, He Fei, Li Chunxia,Yang Piaoping, Design, fabrication, luminescence and biomedical applications of UCNPs@mSiO(2)-ZnPc-CDs-P(NIPAm-MAA) nanocomposites.Journal of Materials Chemistry B, 2016. 4(35): p. 5883-5894.
(23).Yang Dan, Yang Guixin, Gai Shili, He Fei, An Guanghui, Dai Yunlu, Lv Ruichan,Yang Piaoping, Au-25 cluster functionalized metal-organic nanostructures for magnetically targeted photodynamic/photothermal therapy triggered by single wavelength 808 nm near-infrared light.Nanoscale, 2015. 7(46): p. 19568-19578.
(24).Yang Dan, Yang Guixin, Gai Shili, He Fei, Lv Ruichan, Dai Yunlu,Yang Piaoping, Imaging-Guided and Light-Triggered Chemo-/Photodynamic/Photothermal Therapy Based on Gd (III) Chelated Mesoporous Silica Hybrid Spheres.ACS Biomaterials Science & Engineering, 2016. 2(11): p. 2058-2071.
(25).Yang Dan, Yang Guixin, Wang Xingmei, Lv Ruichan, Gai Shili, He Fei, Gulzar Arif,Yang Piaoping, Y2O3:Yb, Er@mSiO(2)-CuxS double-shelled hollow spheres for enhanced chemo-/photothermal anti-cancer therapy and dual-modal imaging.Nanoscale, 2015. 7(28): p. 12180-12191.
(26).Yang Dan, Yang Guixin, Yang Piaoping, Lv Ruichan, Gai Shili, Li Chunxia, He Fei,Lin Jun, Assembly of Au Plasmonic Photothermal Agent and Iron Oxide Nanoparticles on Ultrathin Black Phosphorus for Targeted Photothermal and Photodynamic Cancer Therapy.Advanced Functional Materials, 2017. 27(18).
(27).Yang Guixin, He Fei, Lv Ruichan, Gai Shili, Cheng Ziyong, Dai Yunlu,Yang Piaoping, A cheap and facile route to synthesize monodisperse magnetic nanocrystals and their application as MRI agents.Dalton Transactions, 2015. 44(1): p. 247-253.
(28).Yang Guixin, Lv Ruichan, Gai Shili, Dai Yunlu, He Fei,Yang Piaoping, Multifunctional SiO2@Gd2O3:Yb/Tm Hollow Capsules: Controllable Synthesis and Drug Release Properties.Inorganic Chemistry, 2014. 53(20): p. 10917-10927.
(29).Yang Guixin, Lv Ruichan, He Fei, Qu Fengyu, Gai Shili, Du Shaokang, Wei Zibo,Yang Piaoping, A core/shell/satellite anticancer platform for 808 NIR light-driven multimodal imaging and combined chemo-/photothermal therapy.Nanoscale, 2015. 7(32): p. 13747-13758.
(30).Yang Guixin, Yang Dan, Yang Piaoping, Lv Ruichan, Li Chunxia, Zhong Chongna, He Fei, Gai Shili,Lin Jun, A Single 808 nm Near-Infrared Light-Mediated Multiple Imaging and Photodynamic Therapy Based on Titania Coupled Upconversion Nanoparticles.Chemistry of Materials, 2015. 27(23): p. 7957-7968.
(31).Bi Huiting, Dai Yunlu, Lv Ruichan, Zhong Chongna, He Fei, Gai Shili, Gulzar Arif, Yang Guixin,Yang Piaoping, Doxorubicin-conjugated CuS nanoparticles for efficient synergistic therapy triggered by near-infrared light.Dalton Transactions, 2016. 45(12): p. 5101-5110.
(32).Bi Huiting, Dai Yunlu, Xu Jiating, Lv Ruichan, He Fei, Gai Shili, Yang Dan,Yang Piaoping, CuS-Pt(IV)-PEG-FA nanoparticles for targeted photothermal and chemotherapy.Journal of Materials Chemistry B, 2016. 4(35): p. 5938-5946.
(33).Feng Lili, He Fei, Dai Yunlu, Liu Bin, Yang Guixin, Gai Shili, Niu Na, Lv Ruichan, Li Chunxia,Yang Piaoping, A Versatile Near Infrared Light Triggered Dual-Photosensitizer for Synchronous Bioimaging and Photodynamic Therapy.Acs Applied Materials & Interfaces, 2017. 9(15): p. 12993-13008.
(34).Feng Lili, He Fei, Liu Bin, Yang Guixin, Gai Shili, Yang Piaoping, Li Chunxia, Dai Yunlu, Lv Ruichan,Lin Jun, g-C3N4 Coated Upconversion Nanoparticles for 808 nm Near-Infrared Light Triggered Phototherapy and Multiple Imaging.Chemistry of Materials, 2016. 28(21): p. 7935-7946.
(35).He Fei, Yang Guixin, Yang Piaoping, Yu Yuxiu, Lv Ruichan, Li Chunxia, Dai Yunlu, Gai Shili,Lin Jun, A New Single 808 nm NIR Light-Induced Imaging-Guided Multifunctional Cancer Therapy Platform.Advanced Functional Materials, 2015. 25(25): p. 3966-3976.
(36).Xu Jiating, He Fei, Cheng Ziyong, Lv Ruichan, Dai Yunlu, Gulzar Arif, Liu Bin, Bi Huiting, Yang Dan, Gai Shili, Yang Piaoping,Lin Jun, Yolk-Structured Upconversion Nanoparticles with Biodegradable Silica Shell for FRET Sensing of Drug Release and Imaging-Guided Chemotherapy.Chemistry of Materials, 2017. 29(17): p. 7615-7628.

Honors
Certificate of "Humboldt Fellowship"

Team
Our BIT Team-2020 Our BIT Team-2019
Our Team-2019 Our Team-2018
Ph. D Student: Yanxing WANG BiLIN
Master students
Grade2020: Chenxu LI Xin HUI Yaqun MA Zhenghao LIU
Grade2019:Ruiyi DAI Danyang XU Xiangrong PENG Song SUN
Grade2018: Jun LIU
Grade2017: Miao FENG Xue JIANG Fan YANG

Teaching
For Undergraduate student:
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For Graduate student :
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Admission
Recruitment/Admissions INFORMATION
Doctoral candidate (Year 2020)
The candidate should be master students, with undergraduate and master's degree in chemistry/biology/material science or relative.
Additionally: It is better that the candidate have priority in paper publication，and familiar with chemical synthesis and mateterials sicence, biological experiment, and relative.
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ResearchInterest:
Biomaterials, bioimaging, and cancer theranostics
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Please contact withProf. Ruichan LV ____ Email: rclv@xidian.edu.cn
(School of Life Science and Technology, Xidian University)