姓名
盖中朝
性别
男
出生年月
1988.02

民族
回族
籍贯
河南商丘
最高学位
博士

职称/职务
讲师

社会兼职
陕西省药理学会生化与分子药理学专业委员会委员

联系方式
电话/办公室或研究室
/实验楼1C-415

电子邮箱
zhongchaogai@sust.edu.cn

学习经历
2013-2018年，上海交通大学，博士学位
2010-2013年，华中师范大学，硕士学位
2006-2010年，商丘师范学院，学士学位

工作经历
2018-至今，陕西科技大学教师

研究方向
细胞信号转导、蛋白质工程、天然产物抑菌

主要承担项目及成果（项目、论文、专利、获奖）
1. 承担项目
主持陕西省自然科学基础研究项目1项、陕西省教育厅专项科研计划项目1项、陕西科技大学博士人才科研启动项目1项、参与国家自然基金项目2项。
2. 论文/论著
先后发表SCI学术论文十余篇，部分论文如下：
[1] Zhao J, Wang Y, Li X, Gai Z*. Genome-wide identification and characterization of Toll-like receptors (TLRs) in housefly (Musca domestica) and their roles in the insecticide resistance [J]. Int J Biol Macromol, 2020, 150:141-151. (通讯作者)
[2] Zhao J, Lei Y, Yang Y, Gao H, Gai Z*, Li X*. Metoprolol alleviates arginine vasopressin-induced cardiomyocyte hypertrophy by upregulating the AKT1-SERCA2 cascade in H9C2 cells [J]. Cell & Biosci, 2020, 10:72. (通讯作者)
[3] Gai Z*, Zhao J*. Genome-wide analysis reveals the functional and expressional correlation between RhoGAP and RhoGEF in mouse [J]. Genomics, 2020, 112(2):1694-1706.
[4] Huang J, Fang H, Gai ZC, Mei JQ, Li JN, Hu S, Lv CJ, Zhao WR, Mei LH*. Lactobacillus brevis CGMCC 1306 glutamate decarboxylase: Crystal structure and functional analysis [J]. Biochem Biophys Res Commun, 2018, 503(3):1703-1709.
[5] Kulaberoglu Y, Lin K, Holder M, Gai Z, Gomez M, Assefa Shifa B, Mavis M, Hoa L, Sharif AAD, Lujan C, Smith ESJ, Bjedov I, Tapon N, Wu G*, Hergovich A*. Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control [J]. Nat Commun, 2017, 8(1):695.
[6] Gai Z, Wang Q, Yang C, Wang L, Deng W, Wu G*. Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway [J]. Cell Discov, 2016, 2:16051.
[7] Gai Z, Chu W, Deng W, Li W, Li H, He A, Nellist M, Wu G*. Structure of the TBC1D7-TSC1 complex reveals that TBC1D7 stabilizes dimerization of the TSC1 C-terminal coiled coil region [J]. J Mol Cell Biol, 2016, 8(5):411-425.
[8] Zhang Z, Akyildiz S, Xiao Y, Gai Z, An Y, Behrens J, Wu G*. Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners [J]. Cell Discov, 2015, 1:15016.
[9] Gai Z, Zhang X, Wang X, Peng J, Li Y, Liu K*, Hong H*. Differential proteomic analysis of Trichoplusia ni cells after continuous selection with activated Cry1Ac toxin [J]. Cytotechnology, 2013, 65(3):425-435.
[10] Gai Z, Zhang X, Islam M, Wang X, Li A, Yang Y, Li Y, Peng J, Hong H, Liu K*. Characterization of Atg8 in lepidopteran insect cells [J]. Arch Insect Biochem Physiol, 2013, 84(2):57-77.
3. 获奖
“埃博霉素微生物智造技术集成与应用示范” 2021年获陕西省高等学校科技进步奖二等奖( 排名第2 / 9 )