所属部门：
食品科学与工程学院
职务/职称：
讲师
荣誉：

电子邮件：
wangming@nwu.edu.cn
个人简介
王明，男，中共党员，博士，讲师。主要从事天然产物化学及药理学研究工作。2019年12月毕业于西北大学生命科学学院中药学专业。2020年3月-至今，讲师，西北大学食品科学与工程学院。已在British Journal of Pharmacology, Journal of Agricultural and Food Chemistry, Phytomedicine, Nature Communications等杂志发表SCI论文15篇。
研究成果
论文：
[1] Ming Wang^#, Dan-Qian Chen^#, Lin Chen, Gang Cao, Hui Zhao, Dan Liu, Nosratola DVaziri, Yan Guo, Ying-Yong Zhao*. Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis. British Journal of Pharmacology 2018;(175):2689-2708. [IF=6.583] (TOP期刊，ESI高被引论文)
[2] Ming Wang^#, Dan-Qian Chen^#, Lin Chen, Hui Zhao, Dan Liu, Zhi-Hao Zhang, Nosratola D. Vaziri, Yan Guo, Ying-Yong Zhao*, Gang Cao. Novel RAS inhibitors poricoic acid ZG and poricoic acid ZH attenuate renal fibrosis via Wnt/β-catenin pathway and targeted phosphorylation smad3 signaling. Journal of Agricultural and Food Chemistry 2018;66(8):1828-1842. [IF=3.571] (TOP期刊，ESI高被引论文，ESI热点论文)
[3] Ming Wang^#, Dan-Qian Chen^#, Min-Chang Wang, Hua Chen, Lin Chen, Dan Liu, Hui Zhao, Ying-Yong Zhao*. Poricoic acid ZA, a novel RAS inhibitor, attenuates tubulo-interstitial fibrosis and podocyte injury by inhibiting TGF-β/Smad signaling pathway. Phytomedicine 2017; 36:243-253. [IF=4.180] (TOP期刊)
[4] Ming Wang, Lin Chen, Dan Liu, Hua Chen, Dan-Dan Tang, Ying-Yong Zhao*. Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine. Chemico-Biological Interactions 2017;273:133-141. [IF=3.407] (ESI高被引论文)
[5] Dan-Qian Chen, Gang Cao, Hua Chen, Christos P. Argyopoulos, Hui Yu, Wei Su, Lin Chen, David C. Samuels, Shougang Zhuang, George P. Bayliss, Shilin Zhao, Xiao-Yong Yu, Nosratola D. Vaziri, Ming Wang, Dan Liu, Jia-Rong Mao, Shi-Xing Ma, Jin Zhao, Yuan Zhang, You-Quan Shang, Huining Kang, Fei Ye, Xiao-Hong Cheng, Xiang-Ri Li, Li Zhang, Mei-Xia Meng, Yan Guo, Ying-Yong Zhao*. Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan. Nature Communications 2019;10:1476. [IF=11.878] (TOP期刊，ESI高被引论文)
[6] Lin Chen, Gang Cao, Ming Wang, Ya-Long Feng, Dan-Qian Chen, Nosratola D. Vaziri, Shougang Zhuang, Ying-Yong Zhao*. The matrix metalloproteinase-13 inhibitor poricoic acid ZI ameliorates renal fibrosis by mitigating epithelial-mesenchymal transition. Molecular Nutrition & Food Research 2019;63(13):**. [IF=4.653] (ESI高被引论文)
[7] Dan-Qian Chen, Ya-Long Feng, Lin Chen, Jing-Ru Liu, Ming Wang, Nosratola D. Vaziri, Ying-Yong Zhao*. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/Axl-NF-κB/Nrf2 axis. Free Radical Biology and Medicine 2019;134:484-497. [IF=5.657] (ESI高被引论文)
[8] Dan-Qian Chen, Hua Chen, Lin Chen, Nosratola D. Vaziri, Ming Wang, Xiang-Ri Li, Ying-Yong Zhao*. The link between phenotype and fatty acid metabolism in advanced chronic kidney disease. Nephrology Dialysis Transplantation 2017;32(7):1154-1166. [IF=4.198]
[9] Fang Dou, Hua Miao, Jing-Wen Wang, Lin Chen, Ming Wang, Hua Chen, Ai-Dong Wen*, Ying-Yong Zhao*. An integrated lipidomics and phenotype study reveals protective effect and biochemical mechanism of traditionally used Alisma orientale Juzepzuk in chronic kidney disease. Frontiers in Pharmacology 2018;9:53. [IF=3.845]
[10] Lin Chen, Dan-Qian Chen, Ming Wang, Dan Liu, Hua Chen, Fang Dou, Nosratola D. Vaziri, Ying-Yong Zhao*. Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy. Chemico-Biological Interactions 2017;273:56-72. [IF=3.407]
[11] Dan-Qian Chen, Gang Cao, Hui Zhao, Lin Chen, Tian Yang, Ming Wang, Nosratola D. Vaziri, Yan Guo, Ying-Yong Zhao*. Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum. Therapeutic Advances in Chronic Disease 2019;10:1-19. [IF=4.455]
[12] Xi-Rui He*, Jia-Cheng Fang, Qing Guo, Ming Wang, Yong-Sheng Li, Yi-Bin Meng, Lin-Hong Huang. Advances in antiviral polysaccharides derived from edible and medicinal plants and mushrooms. Carbohydrate Polymers 2020;229:115548. [IF=6.044]
[13] Ya-Long Feng, Gang Cao, Dan-Qian Chen, Nosratola D. Vaziri, Lin Chen, Jun Zhang, Ming Wang, Yan Guo, Ying-Yong Zhao*. Microbiome-metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease. Cellular and Molecular Life Sciences 2019;76(24):4961-4978. [IF=7.014]
[14] Hua Chen, Gang Cao, Dan-Qian Chen, Ming Wang, Nosratola D. Vaziri, Zhi-Hao Zhang, Jia-Rong Mao, Xu Bai, Ying-Yong Zhao*. Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression. Redox Biology 2016;10:168-178. [IF=7.793]
[15] Liu Xiao, Li Qian, Yue Ming*, Zhang Xiao-fei, Zhang Rui-chang, Zhang Bing, Wang Ming. Nitric oxide is involved in integration of UV-B absorbing compounds among parts heterogeneous UV-B environment. Physiologia Plantarum 2015, 155(2):180-191.[IF=2.580]
[16] 王明，刘丹，陈淋，陈丹倩，陈华，赵英永*。中药治疗心脑血管疾病、肝肾损伤及抗炎抗病毒的血清代谢组学研究进展[J]，药物分析杂志，2017,37(9):1549-1556。
[17] 王明，陈振兴，陈革豫，侯宝龙，王翠玲，刘建利*。苯乙烯喹啉衍生物的合成及光学活性[J]，光谱学与光谱分析，2017;37(3): 865-868。
[18] 王明，侯宝龙，闫佳旭，王翠玲，刘建利*。苯乙烯喹啉衍生物的合成及抗癌活性[J]，精细化工，2015, 32 (10):1132-1136。
[20] 王明，巩江，高昂，巩丹青，侯恩太，路锋，倪士峰，崔延堂。食品膨化技术及其养生意义研究概况[J]，安徽农业科学，2010,38(34):19577-19578。
专利：
[1] 刘建利，王明，王翠玲，张宁。樱草素衍生物及其合成方法和应用CNA
[2] 赵英永，王明，陈华。茯苓新酸用于制备利尿药物的应用CNA
[3] 赵英永，陈华，王明。茯苓酸A用于制备利尿药物的应用CNA
获奖情况