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西北工业大学医学研究院导师教师师资介绍简介-卫高菲

本站小编 Free考研考试/2021-07-03


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基本信息 The basic information
卫高菲

医学研究院


博士研究生毕业

理学博士


副教授




药学


wei_gaofei@nwpu.edu.cn




工作经历 Work Experience
2019.09-至今 西北工业大学 医学研究院 副教授

2016.11-2019.08 中山大学 药学院 副研究员

2016.02-2016.10 中化集团 沈阳化工研究院 工程师





教育经历 Education Experience
2006.09-2010.06 本科 沈阳药科大学 药学院 基础药学国家理科基地班
2010.09-2012.06 硕士 沈阳药科大学 制药工程学院 药物化学(导师:刘洋教授)
2012.09-2015.06 博士 沈阳药科大学 制药工程学院 药物化学(导师:程卯生教授)





招生信息 Admission Information
招生专业:
硕士研究生:药学、生物与医药
*欢迎具有药学、生物学、医学及化学等背景的同学报考研究生!


联系方式:
Email: wei_gaofei@nwpu.edu.cn





荣誉获奖 Awards Information
2020年入选陕西省青年科技新星。




科学研究 Scientific Research
主持承担科研项目情况:
1. 国家自然科学基金青年基金:2018.1.1-2020.12.31,负责。

2. 广东省自然科学基金自由申请项目:2017.5.1-2020.4.30,负责。
3. 广东省医学科研基金:2017.7.1-2019.6.30,负责。
4. 中央高校基本科研业务费-中山大学青年教师培育项目:2018.1.1-2019.12.31,负责。
5. 中央高校基本科研业务费-西北工业大学新进教师科研启动项目:2020.1.1-2021.12.1,负责。
6. 陕西省创新能力支撑计划-青年科技新星项目:2021.1.1-2023.12.31,负责



研究方向:
1. 基于肿瘤微环境的小分子前药和纳米递药系统的构建及评价
2. 抗肿瘤药物设计、合成及机制研究





学术成果 Academic Achievements
(#代表共同第一作者,*代表通讯作者。)

Tang X#, Luo X#, Su Q, Wei G*, Meng S*, Chan A*. Chemoselective Dual Functionalization of Phenols via Relay Catalysis of Borane with Different Forms. CCS Chemistry, 2020, 2, 2245–2258.
Wei G*, Sun J, Luan W, Hou Z, Wang S, Cui S, Cheng M*, Liu Y*. A Natural Product AlbA Conjugated with Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate to Inducing Apoptosis-Ferroptosis-M2-TAMs Polarization for Combined Cancer Therapy. J. Med. Chem., 2019, 62, 8760-8772.

Huang Z#, Wei G#, Zeng Z, Huang Y, Huang L, Shen Y, Sun X, Xu C, Zhao C*. Enhanced Cancer Therapy through Synergetic Photodynamic/Immune Checkpoint Blockade Mediated by A Dual Functional Conjugate of Porphyrin and IDO Inhibitor loaded liposome. Theranostics, 2019, 9, 5542-5557.

Wei G#, Huang L#, Shen Y, Huang Z, Xu X, Zhao C*. Porphyrin-Based Porous Organic Frameworks as Oxygen Reservoirs to Overcome Tumor Hypoxia for Enhanced Photodynamic Therapy. Adv. Therap., 2019, **.

Wei G#*, Huang L#, Jiang Y#, Shen Y, Huang Z, Huang Y, Sun X, Zhao C*. Lenvatinib-zinc phthalocyanine conjugates as potential agents for enhancing synergistic therapy of multidrug-resistant cancer by glutathione depletion. Eur. J. Med. Chem., 2019, 169, 53-64.

Wei G, Sun J, Hou Z, Luan W, Wang S, Cui S, Cheng M, Liu Y* Novel antitumor compound optimized from natural saponin Albiziabioside A induced caspase-dependent apoptosis and ferroptosis as a p53 activator through the mitochondrial pathway. Eur. J. Med. Chem., 2018, 157, 759-772.
Huang L#, Wei G#*, Sun X, Jiang Y, Huang Z, Huang Y, Shen Y, Xu X, Liao Y, Zhao C*. A tumor-targeted Ganetespib-zinc phthalocyanine conjugate for synergistic chemo-photodynamic therapy, Eur. J. Med. Chem., 2018, 151, 294-303.

Wei G, Cui S, Luan W, Wang S, Hou Z, Liu Y, Liu Y*, Cheng M*. Natural product-based design, synthesis and biological evaluation of Albiziabioside A derivatives that selectively induce HCT116 cell death. Eur. J. Med. Chem., 2016, 113, 92-101.
Wei G, Luan W, Wang S, Cui S, Li F, Liu Y, Liu Y*, Cheng M*. A library of 1,2,3-triazole-substituted oleanolic acid derivatives as anticancer agents: design, synthesis, and biological evaluation. Org. Biomol. Chem., 2015, 13, 1507-1514.

Wei G, Wang S, Cui S, Guo J, Liu Y, Liu Y*, Cheng M*. Synthesis and evaluation of the anticancer activity of Albiziabioside A and its analogues as apoptosis inducers against human melanoma cells. Org. Biomol. Chem., 2014, 12, 5928-5935.







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