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西北工业大学医学研究院导师教师师资介绍简介-李乐

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基本信息 The basic information
李乐

医学研究院


博士研究生毕业

哲学博士


教授




生物医学工程,生物学-生物物理学


lile5@nwpu.edu.cn




工作经历 Work Experience
2021/03-至今 西北工业大学,医学研究院,教授
2019/01-2020/02 中山大学,附属第一医院,研究员,博导
2014/09-2016/09 美国得克萨斯大学休斯顿健康科学中心,访问****

2010/08-2018/12 中山大学,附属第一医院,副研究员,硕导
2010/07-2010/08香港理工大学,医疗科技与资讯学系,Research Associate
2008/07-2010/06香港理工大学,医疗科技与资讯学系,博士后
2007/03-2008/06 香港理工大学,医疗科技与资讯学系,Research Associate





教育经历 Education Experience
2003/06-2007/12 香港理工大学,医疗科技与资讯学系,博士,导师:Prof. Kaiyu Tong
2000/08-2003/06 西安交通大学,生物医学工程,硕士,导师:郑崇勋教授
1996/09-2000/07西安交通大学,生物医学工程,本科





教育教学 Education And Teaching
《生物电磁特性及应用》课程编码:M22M11003





招生信息 Admission Information
招生专业:
博士研究生:生物医学工程、生物物理学
硕士研究生:生物医学工程、生物物理学
1)医疗仪器与康复工程
2)生物力学与生物物理学
*欢迎具有生物医学工程、生物物理学等相关背景,且有志于从事人体生物力学与生物组织介电特性研究的同学报考硕士、博士研究生!





荣誉获奖 Awards Information
黄东锋 李乐 毛玉瑢 宋嵘 丁明晖 肖湘 鲍晓 林强 赵江莉 徐智勤. 脑卒中多感交互效应运动康复重建技术研究及临床转化。2018年中国产学研合作创新成果一等奖。





科学研究 Scientific Research
主要从事生物力学与康复工程、康复医学与理疗学、生物医学信号处理等领域的工作,重点研究生物力学与医学超声图像建模技术、肌肉组织电阻抗、神经肌肉骨骼系统康复评估、运动分析和表面肌电等。主持包括3项国家自然科学基金在内的10多项科研项目,个人负责经费超过400万。发表SCI论文近70篇(含已录用),其中JCR1区和2区文章26篇,获授权/公开专利9件及软件著作权2件。Google Scholar统计总被引1400+次,单篇最高引用近300次,h-index=19,i10-index=30(截至2020年12月)。





学术成果 Academic Achievements
代表性项目:
1)国家自然科学基金面上项目,**、神经肌肉兴奋变化结合肌肉生物力学参数模型研究脑卒中痉挛肌张力异常的机制、2021-01-2024-12、58万、在研、主持
2)国家自然科学基金面上项目,**、肌肉形态参数和电阻抗生理参数模型研究脑卒中后肌力变化的机制、2018.01-2021.12、61万、在研、主持。
3)国家自然科学基金青年基金, **、 肌肉肌腱力学特性改变对脑卒中步态重建的神经肌肉骨骼建模研究、2012/01-2014/12、 22万、已结题、主持。
4)国家重点研发计划,SQ2019YFC200232,肢体运动功能障碍康复训练系统研制及训练模式研究,2020-01至2024-12,160万,在研,参加(骨干)
代表性专著:
(1) Wai Leung Ambrose Lo, Le LI, Quantitative Evaluation, in Intelligent Biomechatronics in Neurorehabilitation, Ed. Xiaoling Hu, Academic Press(an imprint of Elsevier), London, pp193-208.
(2) Biomechatronics in Medicine and Healthcare 2011.8 ISBN-13: 18 Pan Stanford Publishing,Singapore 编委(3) 国家级实验示范中心《基础医学实验系列教材》医学机能学实验,编委,科学出版社,2013年7月
(4) Applications, Challenges, and Advancements in Electromyography Signal Processing,Hershey, PA: IGI Global. doi:10.4018/978-1-4666-6090-8 编委


代表性论文:
1. Li X, Liu H, Ge L, Yan YF, Lo WLA, Li L*, Wang CH*.Cortical representation of transversus abdominis and multifidus muscles were discrete in patients with chronic low back pain:Evidence elicited by TMS. Neural Plasticity.2021. Accept.
2. Leng Y, LoW#, Hu CP, Bian RH, Xu ZQ, Shan XY, Huang DF*, Li L*.The effects of extracorporeal shock wave therapy on spastic muscle of the wrist joint in stroke survivors: Evidence from neuromechanical analysis.Front Neurosci. 2021.
3. Li X#, Lo WLA#, Lu SW, Liu H, Lin KY, Lai JY, Li L*, Wang CH*.Trunk Muscle Activity during Pressure Feedback Monitoring among Individuals With and Without Chronic Low Back Pain.BMC Musculoskeletal Disorders.2020;21(1):569
4. Yu Zhuang?, Yan Leng?, Shaowei Yao, Jie Zhou, Rong Song*, Le Li*, and Steven W. Su. Voluntary Control of an Ankle Joint Exoskeleton by Able-Bodied Individuals and Stroke Survivors using EMG-Based Admittance Control Scheme. IEEE BME Trans2021
5. Wai Leung Ambrose Lo, Di Lei, Yan Leng, Huanjie Huang, Biru Wang, and Qiuhua Yu and Le Li*. The impact of non-surgical spinal decompression system on paraspinal muscle morphology and mechanical properties in young adults with low back pain.Journal of International Medical Research. 2020. Accept
6. Li X, Liu H, Lin KY, Miao P, Zhang BF, Lu SW, Li L*, Wang CH*. Effects of different sling settings on electromyographic activities of selected trunk muscles: A preliminary research.Biomed Res Int.2020.**. IF=2.276
7. Hu CP#, Hu HJ#, Mai XP, Lo WL*Li L*. Correlation between muscle structures and electrical properties of tibialis anterior in subacute stroke survivors: a pilot study. Front Neurosci. 2019:13;1270.
8. Lo WL, Yu QH; Mao YR; Li WF; Hu CP; Li L*.Lumbar muscles biomechanical characteristics in young people with chronic spinal pain.BMC Musculoskeletal Disorders. 2019;20:559
9. Luo ZC, Lo WL, Bian RH, Wong SF*,Li L*. Advanced Quantitative EstimationMethods for Spasticity: A Literature Review. J Int Med Res. 2019
10. Chen N, Xiao X, Hu H, Chen Y, Song R, Li L*. Identify the alteration of balance control and risk of falling in stroke survivors during obstacle crossing based on kinematic analysis.Front. Neurol. 2019;10:813.
11. Leng Y, Wang Z, Bian RH, Lo WL, Xie XY, Wang RL, Huang DF*, Li L*. Alterations of elastic property of spastic muscle with its joint resistance evaluated from shear wave elastography and biomechanical model. Front. Neurol. 2019;10:736.
12. Xiao X, Hu HJ, Li LF, Li L*. Comparison of Dominant hand to non-dominant hand in conduction of reaching task from 3D kinematic data: trade-off between successful rate and movement efficiency. Mathematical Biosciences and Engineering.2019;16 (3): 1611–1624.
13. Li H, Huang G, Lin Q, Mao RY, Zhao JL, Lo WL, Chen L, DF Huang*, Li L*.Combining Movement-Related Cortical Potentials and Event-Related Desynchronization to Study Movement preparation and execution. Front. Neurol.2018:9;822.
14. Mao YR, Wu XQ, Zhao JL, Lo WL, Chen L, Ding MH, Xu ZQ, Bian RH, Huang DF*, Li L*. The crucial changes of sit-to-stand phases in subacute stroke survivors identified by movement decomposition analysis. Front. Neurol.2018. 9:185.
15. Chen Y, Hu H, Ma C, Zhan Y, Chen N, Li L*, Song R*. Stroke-Related Changes in the Complexity of Muscle Activation during Obstacle-Crossing using Fuzzy Approximate Entropy Analysis.Front. Neurol.,2018;9:131.
16. Li L, Shin H, Stampas A, Li X, Zhou P. Electrical Impedance Myography Changes after Incomplete Cervical Spinal Cord Injury: An Examination of Hand Muscles. Clin. Neurophysiol.2017; 128(11):2242-2247
17. Lin Q, Li H, Mao YR, Lo W, Zhao JL, Chen L, Leng Y, Huang DF* and Li L* The difference of neural networks between bimanual anti-phase and in-phase upper limb movements: a preliminary functional magnetic resonance imaging study. Behavioural Neurology. 2017:**
18. Xiao X, Lin Q, Lo W, Mao YR, Shi XC, Cates RS, Zhou SF, Huang DF*, Li L*. Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-based Training: A Preliminary Study. Behavioural Neurology.2017:**.
19. Li L, Stampas A, Shin H, Li X, Zhou P. Alterations in localized electrical impedance myography of biceps brachii muscles paralyzed by spinal cord injury. Front. Neurol. 2017;8:253.
20. Ma CM, Chen N, Mao YR, Huang DF, Song R, Li L* Alterations of muscle activation pattern in stroke survivors during obstacle crossing. Front. Neurol.2017; 8:70.
21. Li L*, Tong KY. Combined ultrasound imaging and biomechanical modeling to estimate triceps brachii musculotendon changes in stroke survivors. Biomed Res Int. 2016:**.
22. Li L, Li X, Hu H, Shin H, Zhou P*. The Effect of Subcutaneous Fat on Electrical Impedance Myography: Electrode Configuration and Multi-frequency Analyses. Plos One. 2016;11(5):e**.
23. Li L, Shin H, Li X, Li S, Zhou P*. Localized Electrical Impedance Myography of the Biceps Brachii Muscle during Contraction and Fatigue. Sensors (Basel). 2016. 22;16(4).
24. Li L, Li X*, Liu J, Zhou P. Alterations in multidimensional motor unit number index of hand muscles after incomplete cervical spinal cord injury. Front. Hum. Neurosci.2015;9:238.
25. Liu P, Wang YJ, Hu HJ, Mao YR, Huang DF, Li L*. Change of muscle architecture following body weight support treadmill training for persons after subacute stroke: evidence from Ultrasonography. Biomed Res Int. 2014;270676.
26. Li L, Rong W, Ke Z, Hu XL, Tong KY. The effects of training intensities on motor recovery and gait symmetry in a rat model of ischemia. Brain Inj., 2013;27(4):408-416
27. Li L, Rong W, Hu XL, Ke Z, Tong KY.Muscle activation changes during treadmill training after focal cortical ischemia: a rat hindlimb model. J ElectromyogrKinesiol. 2011;21:318-326.
28. Li L, Ke Z, Tong KY, Ying M. Evaluation of cerebral blood flow changes in focal cerebral ischemia rats by using Transcranial Doppler ultrasonography. Ultrasound in Med. & Biol, 2010; 36:595-603.
29. Li L, Tong KY, Hu XL, Hung LK, Koo TKK. Incorporating Ultrasound-Measured Musculotendon Parameters to Subject-Specific EMG-Driven Model to simulate voluntary elbow flexion for Persons after Stroke. Clin. Biomech. 2009; 24:101-109.
30. Li L, Tong KY, Song R, Koo TKK. Is maximum isometric muscle stress the same among prime elbow flexors? Clin. Biomech. 2007; 22: 874-883.
31.Li L, Tong KY, Hu XL. The Effect of Poststroke Impairments on Brachialis Muscle Architecture as Measured by Ultrasound. Arch. Phys. Med. Rehabli. 2007; 88(2):243-250.




代表性奖项:

(1)黄东锋 李乐 毛玉瑢 宋嵘 丁明晖 肖湘 鲍晓 林强 赵江莉 徐智勤. 脑卒中多感交互效应运动康复重建技术研究及临床转化。2018年中国产学研合作创新成果一等奖。
代表性专利成果:
(1) 盛海波 黄东锋 李乐 评估身体平衡的系统和方法中国发明专利:ZL7.8, 中国发明专利,授权公告日2020-08-21
(2) 扈慧静 丁力 吴泽鑫 李乐 王晓云唐丹手指持续被动运动仪, 2015.7.15,中国发明专利,ZL2.0.
(3) 嵘 许跃 蒋庆 张志光 李乐 辅助口颌系统进行康复训练的系统和运动参数记录方法 宋2014.5.7中国发明专利 ZL1.9
(4) 黄东锋 毛玉瑢 李乐 赵江莉 一种上肢实用动作的康复评估工具箱 2018.10.23中国实用新型专利,ZL6.5
(5) 雷迪 陈少贞 李乐 罗洁 卞瑞豪 一种精准运动智能监测系统 中国实用新型专利 ZL5.3, 授权公告日2019年11月12日,公告号 CNU
(6) 黄东锋 毛玉瑢 李乐 软件著作权:脑康复临床科研管理数据平台[简称:康复数据库]V1.0登记号:2020SR**





社会兼职 Social Appointments
中国生物医学工程学会康复工程分会青年委员(2019-)
广东省生物医学工程学会康复工程分会副主任委员(2017-)
中国医师协会整合医学分会整合康复专委会委员(2016-)
广东省康复医学与临床转化工程技术研究中心副主任 (2018-)
SCI期刊Frontiers in Bioengineering and Biotechnology 客座主编
国家自然科学基金(青年、面上等)评议人





团队信息 Team Information
正在组建生物组织介电特性和康复工程研究团队,经费充足,欢迎研究生报考,博士后加入!
办公室地址:西工大友谊校区毅字楼339
lile5@nwpu.edu.cn





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