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山东师范大学生命科学学院导师教师师资介绍简介-孙爽(校内)

本站小编 Free考研考试/2020-12-01



姓名职称:
孙爽,讲师,硕士生导师
教育经历:
2007/09-2011/07山东师范大学,生物系,本科,生物技术专业。
2011/09-2016/12上海交通大学,生命科学学院,博士,生物学专业,导师:何亚文 研究员
工作经历:
2017/07-至今 山东师范大学,生命科学学院,职位:讲师
研究兴趣,领域:
研究方向:病原菌与宿主互作
主要研究方向是病原微生物对宿主细胞骨架特别是微管细胞骨架的影响,关注病原微生物的效应蛋白的种类及分泌方式、病原微生物内效应蛋白的调控方式以及这些效应蛋白进入到宿主细胞内尤其是上皮细胞后对细胞骨架的组装或者功能产生的影响。
开设课程:
本科:微生物学、生物教学课件制作
主持或参加科研项目及人才计划项目情况:
1. 假单胞菌的氧化应激反应在其抑菌活性中的作用(ZR2018BC002),山东省自然科学基金博士基金,2018/03-2020/12,9万元,主持。
2. OxyR调控根际假单胞菌吩嗪-1-羧酸的合成机理研究(2017M622257),山东省自然科学基金博士基金,2017/11-2020/12,5万元,主持。
代表性论文:
1. Sun S*#, Zhou J#,. Phase separation as a therapeutic target in tight junction-associated human diseases. Acta Pharmacol Sin. 2020.
2. Sun S*, Tan LT, Fang YL, Jin ZJ, Zhou L, Goh BH, Lee LH, Zhou J, He YW#. Overexpression of oxyR Increases phenazine-1-carboxylic acid biosynthesis via small rna phrs in the rhizobacterium strain Pseudomonas PA1201. Mol Plant Microbe Interact. 2020;33:488-98.
3. Sun S*#, Zhou J. Molecular mechanisms underlying stress response and adaptation. Thorac Cancer. 2018;9:218-27.
4. Sun S*, Chen B, Jin ZJ, Zhou L, Fang YL, Thawai C, Rampioni G, He YW#. Characterization of the multiple molecular mechanisms underlying RsaL control of phenazine-1-carboxylic acid biosynthesis in the rhizosphere bacterium Pseudomonas aeruginosa PA1201. Mol Microbiol. 2017;104:931-47.
5. Sun S*, Zhou L, Jin K, Jiang H, He YW#. Quorum sensing systems differentially regulate the production of phenazine-1-carboxylic acid in the rhizobacterium Pseudomonas aeruginosa PA1201. Sci Rep. 2016;6:30352.
6. Jin ZJ, Zhou L, Sun S, Cui Y, Song K, Zhang X, He YW#. Identification of a strong quorum sensing- and thermo-regulated promoter for the biosynthesis of a new metabolite pesticide phenazine-1-carboxamide in Pseudomonas strain PA1201. ACS Synth Biol. 2020;9:1802-12.
7. Zhou L, Sun S, Zhang W, He YW#. Ultra-performance liquid chromatography/mass spectrometry for the detection and quantification of diffusible signal factor (DSF) family quorum-sensing signals. Methods Mol Biol. 2018;1673:97-105.
8. Jin K, Zhou L, Jiang H, Sun S, Fang Y, Liu J, Zhang X, He YW#. Engineering the central biosynthetic and secondary metabolic pathways of Pseudomonas aeruginosa strain PA1201 to improve phenazine-1-carboxylic acid production. Metab Eng. 2015;32:30-8.
9. Zhou L, Li M, Wang XY, Liu H, Sun S, Chen H, Poplawsky A, He YW#. Biosynthesis of coenzyme Q in the phytopathogen Xanthomonas campestris via a Yeast-like pathway. Mol Plant Microbe Interact. 2019;32:217-26.
10. Fang YL, Chen B, Zhou L, Jin ZJ, Sun S, He YW#. The anti-activator QslA negatively regulates phenazine-1-carboxylic acid biosynthesis by interacting with the quorum sensing regulator MvfR in the rhizobacterium Pseudomonas aeruginosa strain PA1201. Front Microbiol. 2018;9:1584.
11. Zhou L, Jiang HX, Sun S, Yang DD, Jin KM, Zhang W, He YW#. Biotechnological potential of a rhizosphere Pseudomonas aeruginosa strain producing phenazine-1-carboxylic acid and phenazine-1-carboxamide. World J Microbiol Biotechnol. 2016;32:50.



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