王康^1,2, 崔玉琳^1,3, 高政权⁴, 孟春晓⁴, 秦松^1,3
1.中国科学院烟台海岸带研究所 海岸带生物学与生物资源保护重点实验室, 山东 烟台 264003;2.中国科学院大学, 北京 100049;3.中国科学院海洋大科学研究中心, 山东 青岛 266071;4.滨州医学院 药学院, 山东 烟台 264003

摘要:
微藻在生产蛋白质、油脂、色素等方面具有作为细胞工厂的潜力，在解决传统生物量生产和市场未来的一些局限性方面发挥着推进作用。基因工程促进了微藻的改良，推动了微藻的产业化进程。本文综述了近年来微藻基因工程的研究进展以及基因工程在微藻生产生物燃料、医药等方面的应用。本文能为基因工程技术在微藻中的研究及应用提供思路，从而使微藻以及微藻产品变得更具有经济竞争力。
关键词:微藻细胞工厂高价值化合物基因工程
DOI：10.11759/hykx20191122003
分类号:
基金项目:国家自然科学基金（31972815）

Application of microalgae genetic engineering in the production of high-value compounds
WANG Kang^1,2, CUI Yu-lin^1,3, GAO Zheng-quan⁴, MENG Chun-xiao⁴, QIN Song^1,3
1.Key Laboratory of Coastal Biology and Biological Resource Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China;2.University of Chinese Academy of Sciences, Beijing 100049, China;3.Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China;4.School of Pharmacy, Binzhou Medical University, Yantai 264003, China
Abstract:
Microalgae has the potential to be a cell factory in the production of proteins, oils, and pigments and is crucial in solving problems of traditional biomass production and future market. Genetic engineering promotes the improvement and industrialization of microalgae. In this paper, the research progress of microalgae genetic engineering and genetic engineering application in the microalgae production of biofuels and medicines are reviewed. This article can provide some ideas for the research and application of genetic engineering technology in microalgae, thereby facilitating microalgae and microalgae products to become more economically competitive.
Key words:microalgaecell factoryhigh-value compoundsgenetic engineering





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