杨端鹏¹, 李仲先¹, 王胜男¹, 牛建峰², 王广策², 李健^1,3
1.攀枝花学院生物与化学工程学院, 四川 攀枝花 617000;2.中国科学研究院海洋研究所, 山东 青岛 266071;3.攀枝花市格萨拉生物技术有限公司, 四川 攀枝花 617000

摘要:
微藻是单细胞小型光合生物，是自然界最重要的初级生产者，在食品、能源、医药和环境等行业领域有重要应用。微藻生物技术产业发展所需要的优良微藻株系，除了通过筛选获得外，还可以利用基因诱变或者基因工程等方法获得。利用基因诱变方法获得的突变株，不是转基因作物，且具有更适宜生产需要的优良性状。本文主要综述基因诱变在微藻育种中最新的应用研究进展，为微藻产业化研发工作提供参考。
关键词:微藻基因诱变育种突变株筛选高附加值产品
DOI：10.11759/hykx20201103001
分类号:Q943
基金项目:攀枝花市重点科技技术项目（2018CY-N-5）；四川省科技厅重点科技计划项目（2019YFN0121）；四川大学攀枝花市产业联合创新基金项目（2019CDPZH-19）；四川省留学归国人员创业启动计划项目

Advances in the research and application of mutagenesis in microalgae
YANG Duan-peng¹, LI Zhong-xian¹, WANG Sheng-nan¹, NIU Jian-feng², WANG Guang-ce², LI Jian^1,3
1.College of Biological and Chemical Engineering, Panzhihua University, Panzhihua 617000, China;2.Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China;3.Panzhihua Gesala Biotechnology Co. Ltd., Panzhihua 617000, China
Abstract:
Microalgae are single-cell, photosynthetic organisms and primary producers. They have vital applications in the fields of food, energy, and medicine and the environment. Wild-type strains of microalgae have been used in industry after collection and selection efforts. The genotypes and phenotypes of wild-type strains can be improved through mutagenesis and genetic engineering. Mutants acquired through mutagenesis are not considered genetically modified organisms; however, they may bear superior traits for industrial applications. In this study, we have reviewed advances in mutagenesis of microalgal genes and provided insights for applying this methodology for the industrial exploitation of microalgae.
Key words:microalgaegene mutagenesisscreening of mutantshigh value-added products





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