梁淑静 讲师，主治医师
硕士招生类型：学术型
硕士招生专业：肿瘤学
博士招生类型：无
博士招生专业：无
所在院系：附属东方医院
联系方式：liangshujing02@126.com
课题组链接：
研究方向
主要任职
科研业绩

乳腺癌等免疫治疗及纳米材料在其治疗中的应用The application of nanomaterials and immunotherapy in breast cancer and other types of tumors
同济大学附属东方医院主治医师，同济大学硕士生及本科生导师Attending doctor of Breast Cancer Center in Shanghai East Hospital, affiliated to Tongji University School of Medicine;master and undergraduate students tutor of Tongji University
目前已参与多项生物纳米及肿瘤免疫相关领域相关研究工作，掌握乳腺癌及其它肿瘤免疫治疗及纳米材料应用领域的最新研究进展，熟悉免疫细胞的分离培养，掌握小鼠乳腺原位荷瘤鼠模型的建立，及分子生物学实验等技术。本课题申请者承担国家自然科学基金、浦东新区卫计委卫生科研青年项目及优秀青年人才培养行动计划等多项科研课题，已在纳米生物医学相关领域SCI及核心期刊杂志发表文献数篇。协助培养多名硕士生及博士生。具备临床及科研工作的能力及基础。
At present, she has participated in multiple research work in the fields of bio-nano and tumor immunization, mastered the latest research progress of the immunotherapy and nanomaterial application in breast cancer, and been familiar with the isolation and culture of immune cells, establishment of tumor-bearing mouse model and molecular biology experiments technologies. She has also undertaken a number of scientific research projects such as the National Nature Science Foundation of China, the Project of Excellent Youth Training of Tongji University, and the Youth Project of Health and Family Planning Committee of Pudong New Area and so on. Several articles have been published in SCI and core journals related to nanobiomedicine. She has assisted in the postgraduate training of the department of Breast Cancer Center, and possessed the clinical and scientific research ability.
代表性论文（Representative paper）：1.Shujing Liang, Chao Li, Chunlei Zhang, etc.CD44v6 Monoclonal Antibody-Conjugated Gold Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy of Gastric Cancer Stem-like Cells [J]. Theranostic, 2015, 5(9): 970-984.(IF:8.854)
2.Yonglin Lu, Yain Ma, Chan Feng, Donglei Zhu, Jie Liu, Lv Chen, Shujing Liang?, Chunyan Dong?. Co-delivery of Cyclopamine and Doxorubicin Mediated by Bovine Serum Albumin Nanoparticles Reverses Doxorubicin Resistance in Breast Cancer by Down-regulating P-glycoprotein Expression [J]. J Cancer, 2019,10(10):2357-2368. (IF:3.182)
3.Chao Li, Shujing Liang, Chunlei Zhang, Yanlei Liu, Meng Yang, Jingpu Zhang, Xiao Zhi, Fei Pan, Daxiang Cui. Allogenic dendritic cell and tumor cell fused vaccine for targeted imaging and enhanced immunotherapeutic efficacy of gastric cancer [J]. Biomaterial, 2015, 54, 177-187.(IF: 8.557 )
4.Chao Li, Ji Yang, Can Wang, Shujing Liang, Fei Pan, Chunlei Zhang, Feng Chen, Hualin Fu, Kan Wang and Daxiang Cui. BRCAA1 antibody-and Her2 antibody-conjugated amphiphilic polymer engineered CdSe/ZnS quantum dots for targeted imaging of gastric cancer[J]. Nanoscale Res Lett, 2014, 9, 1-13. (IF:2.779)
5.Zhang C, Li C, Liu Y, Jingpu Zhang, Chenchen Bao, Shujing Liang, Qing Wang, Yao Yang, Hualin Fu, Kan Wang, and Daxiang Cui. Gold Nanoclusters‐Based Nanoprobes for Simultaneous Fluorescence Imaging and Targeted Photodynamic Therapy with Superior Penetration and Retention Behavior in Tumors[J]. Advanced Functional Materials, 2015, 25, 1314–1325 (IF:11.805)
6.Liang Xu, Xiaobo Wu, Chun Hu, Zhiying Zhang, Le Zhang, Shujing Liang, Yingchun Xu, Fengchun Zhang. A meta-analysis of combination therapy versus single-agent therapy in anthracycline- and taxane-pretreated metastatic breast cancer: results from nine randomized Phase III trials. Onco Targets Ther. 2016, Jul 4;9:4061-74(IF:2.272).
7.Liang Xu, Le Zhang, Chun Hu, Shujing Liang, Xiaochun Fei, Ningning Yan, Yanyun Zhang, Fengchun Zhang. WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and metastasis of breast cancer stem cells. Int J Oncol. 2016 Mar;48(3):1175-86(IF: 2.371).
8.Chun Hu, Liang Xu, Shujing Liang, Zhiying Zhang, Yanyun Zhang, Fengchun Zhang. Lentivirus-mediated shRNA targeting Nanog inhibits cell proliferation and attenuates cancer stem cell activities in breast cancer. J Drug Target. 2016;24(5):422-32(IF:2.821).
9.梁淑静，徐丽敏等.疣状表皮发育不良的共聚焦激光扫描显微镜下表现[J]. 中国皮肤性病学杂志，2011,25(3):231-233.2
10.梁淑静，徐丽敏等. 扁平苔藓的共聚焦激光扫描显微镜特征表现[J].临床皮肤科杂志，2011,40（3）：139-141.