秦楠 研究员
硕士招生类型：学术型
硕士招生专业：基础医学
博士招生类型：学术型
博士招生专业：基础医学
所在院系：附属第十人民医院
联系方式：qinnan001@126.com
课题组链接：
研究方向
主要任职
科研业绩

1.病原体诊断及耐药性
2.肠道菌群与感染性疾病的关系
3.高通量测序及生物信息学
1. Pathogen diagnosis and drug resistance.
2.The relationship between human microbiome and infectious diseases and metabolic diseases.
3.High-throughput sequencing and bioinformatics.
中华预防医学会微生态学分会常务委员；
中华预防医学会微生态学分会青年委员会副主任委员；
中国食品科学技术学会青年工作委员会委员；
《中国微生态学杂志》编辑委员会委员；
中山大学附属第一医院特聘专家；
上海锐翌生物科技有限公司创始人。
The permanent council member of the Microecology Section, deputy director of the youth council and deputy team leader of digestion and nutrition of Chinese Preventive Medicine Association.
Member of the youth council of the Chinese Institute of Food Science and Technology.
Member of the editorial committee of "Chinese Journal of Microecology".
Distinguished expert of the First Affiliated Hospital of Sun Yat-sen University.
Founder of Shanghai Realbio Technology.
秦楠教授近期的研究工作揭示了空气颗粒物所附着的微生物种类，及其对呼吸道相关疾病等城市公共卫生的影响，相关研究成果发表在《Genome Biology》期刊上。秦教授曾任浙江大学附属第一医院感染性疾病诊治国家重点实验室特聘研究员，博士生导师，期间肝硬化肠道菌群宏基因组研究成果两次发表在《Nature》上，并入选2014年度高校十大科技进展。美国弗吉尼亚理工大学微生物学博士。2008-2011年任华大基因（BGI）微生物基因组部门负责人。秦教授作为项目负责人或主要参与者主持及参加了十余项国家及省部级的科研项目、人才计划项目。2009年至今共发表论文40余篇。曾获评2017年第七批上海市海外高层次人才引进计划专家，2015年盖茨基金会-大挑战青年科学家，2015年第二届树兰医学青年奖。
Professor Nan Qin’s recent research has been published in the journal Genome Biology, which has revealed the types of microorganisms attached to airborne particles and their impact on urban public health such as respiratory-related diseases. Prof. Qin received his Ph.D. from the Department of Biological Sciences, Virginia Tech, US in 2008. Afterwards, he joined BGI in Shenzhen as the director of department of microbial genomics. In 2011, he joined Zhejiang University School of Medicine as a Visiting-Fellow and doctoral supervisor in Collaborative Innovation Center of Diagnosis and Treatment of Infectious Diseases, and his research about metagenomics of gut microbiome in liver cirrhosis has been published in Nature in 2014 and 2015. Prof. Qin has presided over or participated in a number of national, provincial and ministerial scientific research projects and talent plan projects. He has more than 40 papers in Nature, Science, PLOS Biology and other top academic journals since 2009. He was recognized as the Shanghai Overseas High-level Talent Program Expert, and one of Grand Challenges 2015-Young Scientists by Ministry of Science and Technology and Bill & Melinda Gates Foundation, and won the 2nd Shulan Medical Youth Award.
Key publications:
1.Nan Qin#, Emmanuelle Le Chatelier#, Jing Guo, Edi Prifti, Lanjuan Li & S. Dusko Ehrlich. Decompensated cirrhosis and microbiome interpretation Reply [J]. Nature, 2015, 525(7569): E2-E3.
2.Nan Qin#, Fengling Yang#, Ang Li#, Edi Prifti# , Yanfei Chen#, Li Shao#, Jing Guo, Emmanuelle Le Chatelier, Jian Yao, Lingjiao Wu, Jiawei Zhou, Shujun Ni, Lin Liu, Nicolas Pons, Jean Michel Batto, Sean P. Kennedy, Pierre Leonard, Chunhui Yuan, Wenchao Ding, Yuanting Chen, Xinjun Hu, Beiwen Zheng,Guirong Qian, Wei Xu, S. Dusko Ehrlich*, Shusen Zheng* & Lanjuan Li*. Alterations of the human gut microbiome in liver cirrhosis [J]. Nature, 2014, 513(7516): 1-6.
3.Roberto Bonasio#, Guojie Zhang#, Chaoyang Ye#, Navdeep S. Mutti#, Xiaodong Fang#, Nan Qin#, Greg Donahue, Pengcheng Yang, Qiye Li, Cai Li, Pei Zhang, Zhiyong Huang, Shelley L. Berger*, Danny Reinberg*, Jun Wang*, Jürgen Liebig*. Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator [J]. Science, 2010, 329 (5995), 1068-1071.
4.Renyuan Gao#, Zhiguo Wang#, Hao Li#, Zhan Cao, Zhiguang Gao, Hongqi Chen, Xiaohui Zhang, Dengdeng Pan, Rong Yang, Hui Zhong, Rongrong Shen, Lu Yin, Zhenyi Jia, Tongyi Shen, Nan Qin*, Zhiqian Hu*, Huanlong Qin*. Gut microbiota dysbiosis signature is associated with the colorectal carcinogenesis sequence and improves the diagnosis of colorectal lesions [J]. Journal of Gastroenterology and Hepatology, 2020.
5.Nan Qin*#, Peng Liang#, Chunyan Wu#, Guanqun Wang, Qian Xu, Xiao Xiong, Tingting Wang, Moreno Zolfo, Nicola Segata, Huanlong Qin, Rob Knight, Jack A. Gilbert* and Ting F. Zhu*. Longitudinal survey of microbiome associated with particulate matter in a megacity [J]. Genome Biology, 2020, 21:55, 1-11.
6.Zi Ye#, Chunyan Wu#, Ni Zhang#, Liping Du, Qingfeng Cao, Xinyue Huang, Jihong Tang, Qingfeng Wang, Fuzhen Li, Chunjiang Zhou, Qian Xu, Xiao Xiong, Aize Kijlstra, Nan Qin*, Peizeng Yang*. Altered gut microbiome composition in patients with Vogt-Koyanagi-Harada disease [J]. Gut Microbes, 2020, 2-17.
7.Yuan Wang#, Sa Wang#, Chunyan Wu#, Xi Chen, Zhuhui Duan, Qian Xu, Wen Jiang, Lei Xu, Tingting Wang, Lingkai Su, Ying Wang, Yadong Chen, Jie Zhang, Yun Huang, Suman Tong, Cheng Zhou, Shuli Deng*, Nan Qin*. Oral Microbiome Alterations Associated with Early Childhood Caries Highlight the Importance of Carbohydrate Metabolic Activities [J]. mSystems, 2019, 4:6, 1-15.
8.Yi Zheng#, Tingting Wang#, Xiaoxuan Tu, Yun Huang, Hangyu Zhang, Di Tan, Weiqin Jiang, Shunfeng Cai, Peng Zhao, Ruixue Song, Peilu Li, Nan Qin* & Weijia Fang*. Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma [J]. ournal for ImmunoTherapy of Cancer, 2019, 7:193, 1-7.
9.Bingbing Xiao*#, Chunyan Wu#, Wenfeng Song, Xiaoxi Niu, Nan Qin, Zhaohui Liu & Qian Xu*. Association Analysis on Recurrence of Bacterial Vaginosis Revealed Microbes and Clinical Variables Important for Treatment Outcome [J]. Frontiers in Cellular and Infection Microbiology, 2019, 9:189, 1-11.
10.Zi Ye#, Ni Zhang#, Chunyan Wu, Xinyuan Zhang, Qingfeng Wang, Xinyue Huang, Liping Du, Qingfeng Cao, Jihong Tang, Chunjiang Zhou, Shengping Hou, Yue He, Qian Xu, Xiao Xiong, Aize Kijlstra, Nan Qin, Peizeng Yang*. A metagenomic study of the gut microbiome in Behcet’s disease [J]. Microbiome, 2018, 6: 135, 1-13.
11.Yiwei Qian#, Xiaodong Yang#, Shaoqing Xu, Chunyan Wu, Yanyan Song, Nan Qin*, Sheng-Di Chen*, Qin Xiao*. Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease [J]. Brain, Behavior, and Immunity, 2018, 70:194-202.
12.Yiwei Qian#, Xiaodong Yang#, Shaoqing Xu, Chunyan Wu, Nan Qin*, Sheng-Di Chen* and Qin Xiao*. Detection of Microbial 16S rRNA Gene in the Blood of Patients with Parkinson’s Disease [J]. Frontiers in Aging Neuroscience, 2018, 10(156): 1-11.
13.Chengping Wen#*, Zhijun Zheng#, Tiejuan Shao#, Lin Liu#, Zhijun Xie#, Emmanuelle Le Chatelier, Zhixing He, Wendi Zhong, Yongsheng Fan, Linshuang Zhang, Haichang Li, Chunyan Wu, Changfeng Hu, Qian Xu, Jia Zhou, Shunfeng Cai, Dawei Wang, Yun Huang, Maxime Breban, Nan Qin* and Stanislav Dusko Ehrlich*. Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis [J]. Genome Biology, 2017, 18(1):142. 1-13.