姓名：张亚琼

职称：副研究员，硕士生导师

所属学科： 食品科学与工程

研究方向：
（1）食品功能因子递送体系的可控构建与评价
（2）食品功能因子的健康效应及营养干预机制
电话：
电子信箱： yqzhang2006@sjtu.edu.cn



个人简历：
张亚琼，女，博士，先后获得上海交通大学生物工程本科、药剂学硕士和生物医学工程博士学位。主要从事功能食品、食品营养与食品毒理学领域的基础及应用基础研究工作。近些年主持及参与国家自然科学基金面上项目、国家自然科学基金青年项目、“十三五”国家重点研发计划项目、农业部公益性行业项目、北京食品营养与人类健康高精尖创新中心开放基金以及企业横向等多项科研项目。相关成果已在国际重要学术期刊上发表学术论文30余篇，其中JCR一区/二区论文18篇，ESI高被引论文1篇；以第一发明人，申请公开发明专利4项，授权专利2项；参编英文专著1部；获得2018年金龙鱼青年教师奖；2011年度上海市自然科学奖三等奖1项（第三完成人）；2011年入选上海交通大学SMG-晨星青年****奖励计划优秀青年教师C类。2018年，指导的2名本科生获得第三届“绿谷杯”本科生课外科技创新项目成果组二等奖。担任国际期刊Acta Scientific Nutritional Health编委一职，食品领域国际期刊Journal of Agricultural and Food Chemistry、Food Chemistry、Food Hydrocolloids、International Journal of Biological Macromolecules等特邀审稿人；多次受邀在美国化学会年会、美国食品科技协会年会和国际功能食品年会上做大会报告，获得国际学术界和企业届的广泛关注。

主持或参加的主要科研项目：
国家自然科学基金面上项目：玉米醇溶蛋白/酪蛋白酸钠/果胶复合颗粒的可控构建及其用于食品营养递送体系的研究（项目批准号：**），2019.1-2020.12，项目负责人
国家自然科学基金青年项目：基于可食用蛋白/壳聚糖盐自组装构建姜黄素结肠释放载运体系的研究（项目批准号：**），2016.1-2018.12，项目负责人
“十三五”国家重点研发计划：风险因子与代谢标志物表征研究（课题编号：2017YFC**），2018.1-2021.12，子课题负责人
农业部公益性行业项目子课题：未知毒物的早期检测技术研究（课题编号：-1），2012.1-2016.12，项目负责人
北京食品营养与人类健康高精尖创新中心开放基金项目：3-氯丙醇酯的体内吸收、分布、代谢以及潜在的致毒代谢物研究，2017.1-2019.12，项目负责人
企业委托横向项目：粮油制品质量控制与功能化技术研究，2015.4-2016.3，项目负责人
企业委托横向项目：Sn-2棕榈酸对大鼠钙吸收和脂肪吸收的影响及其机制研究，2017.1-2017.12，项目负责人
“十三五”国家重点专项项目的子课题：番茄酱汁类制品加工过程中质量品质控制技术（子课题编号：2016YFD**）2016.6-2020.12，子课题骨干

专利：
张亚琼，姚芳懿，一种新的酪蛋白衍生物及其制备方法，发明专利，授权号：ZL 6.4
张亚琼，姚芳懿，姜黄素复合颗粒及其制备方法和应用，发明专利，公开号：3.7
张亚琼，姚芳懿，一种经改性的蛋白及其制备方法和应用，发明专利，公开号：0.6
赵越，张亚琼，陆维盈，一种除去3-氯丙二醇酯的方法，发明专利，公开号：5.6
张亚琼，杨普煜，结构脂OPO的应用，发明专利，公开号：6.4

近五年代表性论文：
Jinli Xue, Yaqiong Zhang*, Guoren Huang, Jie Liu, Margaret Slavin, Liangli (Lucy) Yu. Zein-caseinate composite nanoparticles for bioactive delivery using curcumin as a probe compound, Food Hydrocolloids, 2018, 83, 25-35
Yaqiong Zhang, Fangyi Yao, Jie Liu, Wen Zhou, Liangli (Lucy) Yu*, Synthesis and characterization of alkylated caseinate, and its structure-curcumin loading property relationship in water, Food Chemistry, 2018, 244:246-253
Yaqiong Zhang, Puyu Yang, Fangyi Yao, Jie Liu, Liangli (Lucy) Yu*, Grafting C8-C16 alkyl groups altered the self-assembly and curcumin-loading properties of sodium caseinate in water, Data in Brief, 2018, 16, 276-285.
Puyu Yang, Hong Zhang, Junchen Liu, Jinyu Hu, Jianchun Wan, Yaqiong Zhang*, Liangli Yu*, Review of Sn-2 Palmitate implications for infant health, Journal of Food Science and Technology (in Chinese), 2018, 36(4), 12-17.
Fangyi Yao, Yaqiong Zhang*, Liangli (Lucy) Yu. The Effect of Caseinate Derivatives on the Redispersibility and Storage Stability of Freeze-dried Zein Nanoparticles, Journal of Chinese Institute of Food Science and Technology (in Chinese), 2018, 18 (11): 152-158
Jianchun Wan, Songyou Hu, Jorg J. Jacoby, Jie Liu, Yaqiong Zhang*, Liangli (Lucy) Yu*, The impact of dietary sn-2 palmitic triacylglycerols in combination with docosahexaenoic acid or arachidonic acid on lipid metabolism and host faecal microbiota composition in Sprague Dawley rats, Food & Function, 2017, 8, 1793-1802.
Boyan Gao, Yinghua Luo, Weiying Lu, Jie Liu, Yaqiong Zhang*, Liangli (Lucy) Yu*, Triacylglycerol compositions of sunflower, corn and soybean oils examined with supercritical CO2 ultra-performance convergence chromatography combined with quadrupole time-of-flight mass spectrometry, Food Chemistry, 2017, 218, 569-574.
Yue Zhao¹, Yaqiong Zhang¹, Zhongfei Zhang, Jie Liu, Yi-lin Wang, Boyan Gao, Yuge Niu, Xiangjun Sun, Liangli Yu*, Formation of 3-MCPD fatty acid esters from monostearoyl glycerol and the thermal stability of 3-MCPD monoesters, Journal of Agricultural and Food Chemistry, 2016, 64, 8918-8926.（Co-first author）
Yaqiong Zhang, Yuge Niu, Fangyi Yao, Bona Dai, Qin Wang, Liangli (Lucy) Yu*, Preparation of novel cross-linked and octylated caseinates using a biphasic enzymatic procedure and their functional properties, Journal of Agricultural and Food Chemistry, 2014, 62(34):8655-8662
Yaqiong Zhang, Yuge Niu, Yangchao Luo, Mei Ge, Tian Yang, Liangli (Lucy) Yu*, Qin Wang, Fabrication, characterization and antimicrobial activities of thymol-loaded zein nanoparticles stabilized by sodium caseinate-chitosan hydrochloride double layers, Food Chemistry, 2014,142:269-275
Shengmin Zhou, Yueqiang Wang, Jorg J. Jacoby, Yuanrong Jiang, Yaqiong Zhang, Liangli (Lucy) Yu*, Effects of medium- and long-chain triacylglycerols on lipid metabolism and gut microbiota composition in C57BL/6C mice, Journal of Agricultural and Food Chemistry, 2017, 65:6599-6507
Jie Liu, Yanfang Li, Puyu Yang, Jianchun Wan, Qimeng Chang, Thomas T.Y. Wang, Weiying Lu, Yaqiong Zhang, Qin Wang, Liangli (Lucy) Yu*, Gypenosides reduced the risk of overweight and insulin resistance in C57BL/6J mice through modulating adipose thermogenesis and gut microbiota, Journal of Agricultural and Food Chemistry, 2017, 65: 9237-9246.
Yanfang Li, Puyu Yang, Qimeng Chang, Jing Wang, Jie Liu, Yuan Lv, Thomas T.Y. Wang, Boyan Gao, Yaqiong Zhang, Liangli (Lucy) Yu*, Inhibitory effect of piceatannol on TNF-α-mediated inflammation and insulin resistance in 3T3-L1 adipocytes, Journal of Agricultural and Food Chemistry, 2017, 65(23), 4634-4641
Boyan Gao, Man Liu, Guoren Huang, Zhongfei Zhang, Yue Zhao, Thomos Wang, Yaqiong Zhang, Jie Liu, Liangli Yu. * Absorption, distribution, metabolism and excretion of 3-MCPD 1-monopalmitate after oral administration in rats, Journal of Agricultural and Food Chemistry, 2017, 65, 2609-2614.
Lei Chen, Jie Liu, Yaqiong Zhang, Bona Dai, Yuan An, Liangli (Lucy) Yu*, Structural, thermal, and anti-inflammatory properties of a novel pectic polysaccharide from Alfalfa (Medicago sativa L.) stem, Journal of Agricultural and Food Chemistry, 2015,63(12): 3219-3228
Lei Chen, Jie Liu, Yaqiong Zhang, Yuge Niu, Bona Dai, Liangli (Lucy) Yu*, A novel alkaline Hemicellulosic Heteroxylan isolated from Alfalfa (Medicago sativa L.) stem and Its thermal and anti-inflammatory properties, Journal of Agricultural and Food Chemistry, 2015,63(11): 2970-2978