导师姓名： 陈诗慧 专业代码： 100100
性别： 女 专业名称： 基础医学
培养单位： 基础医学院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式： 办公室电话：-776598电子邮箱：chensh2015@shsmu.edu.cn
邮编： 200025 邮箱地址： chensh2015@shsmu.edu.cn

研究方向 (点击浏览详细信息)
骨代谢疾病靶向治疗和病理机制研究

社会任职
国际华人骨研学会会员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
KJ 激素性骨坏死靶向治疗及病理机制研究 上海交通大学“新进青年教师启动计划” 2016-01~2018-12 20万元 课题负责人
BJ** 激素性骨坏死靶向治疗及病理机制研究 上海交通大学医学院基础医学院“海外引进人才”计划” 2015-10~2018-09 80万元 课题负责人
No. QC2013C051 含植物小分子icaritin的复合生物材料在骨修复的应用研究 黑龙江省自然科学基金青年科学基金 2014-01~2016-12 25万元 课题负责人
No. ** 新型快速成型技术构建的复合植物小分子icaritin 的生物支架材料在标准骨缺损复中的应用 国家自然科学基金委青年科学基金 2014-01~2016-12 5万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Chen SH* （通讯作者）, Wang XL, Zheng LZ, Dai Y, Zhang JY, Guo BL, Yang ZJ, Yao XS, Qin L* Comparative study of two types of herbal capsules with different Epimedium species for prevention of OVX-induced osteoporosis in rats J Orthop Transl 2015 DOI:10.1016/j.jot.2015.07.001
Qin L*, Yao D, Zheng L, Liu WC, Liu Z, Lei M, Huang L, Xie X, Wang X, Chen Y, Yao X, Peng J, Gong H, Griffith JF, Huang Y, Zheng Y, Feng JQ, Liu Y, Chen SH, Xiao D, Wang D, Xiong J, Pei D, Zhang P, Pan X, Wang X, Lee KM, Cheng CY Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits Biomaterials 2015 9:125-43
Zheng LZ, Cao HJ, Chen SH, Tang T, Fu WM, Huang L, Chow HK, Wang YX, Griffith JF, Zhao DW, Zhang G, Wang XL, Qin L* Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in rabbits J Bone Miner Res 2015 DOI: 10.1002/jbmr.2542
Li HF, Xie XH, Zheng YF, Cong Y, Zhou FY, Qiu KJ, Wang X, Chen SH, Huang L, Tian L. Qin L* Development of biodegradable Zn-1X binary alloys with nutrient alloying elements Mg, Ca and Sr Sci Rep 2015 5:10719. DOI: 10.1038/srep10719.
Zheng LZ, Wang XL, Cao HJ, Chen SH, Huang L, Qin L* Src siRNA prevents corticosteroid-associated osteoporosis in a rabbit model Bone 2015 DOI: 10.1016/j.bone.2015.11.010
Chen SH* （通讯作者）, Zheng LZ, Xie XH, Lei M, Wang XL, Lai YQ, Chen SK, Zhang M, Wang YX, James FG, Qin L* Comparative study of PLGA/TCP scaffolds incorporated or coated with osteogenic growth factors for enhancement of bone regeneration J Orthop Transl 2014 DOI: 10.1016/j.jot.2014.01.002
Chen SH, Lau PY, Lei M, Peng J, Tang T, Wang XH, Qin L*, Kumta SM* Segmental Composite Porous Scaffolds with either Osteogenesis or Anti-bone Resorption Property Tested in a Rabbit Ulna Defect Model J Tissue Eng Regen Med 2013 DOI: 10.1002/term.1828
Chen SH, Lei M, Xie XH, Zheng LZ, Yao D, Wang XL, Li W, Zhao Z, Kong A, Xiao DM, Wang DP, Pan XH, Wang YX, Qin L* A PLGA/TCP composite scaffold incorporating bioactive phytomolecule icaritin for enhancement of bone defect repair in rabbits Acta Biomater 2013 9(5): 6711-22
Wang XL, Xie XH, Zhang G, Chen SH, Yao D, He K, Wang XH, Yao XS, Leng Y, Fung KP, Leung KS, Qin L* Exogenous phytoestrogenic molecule icaritin incorporated into a porous scaffold for enhancing bone defect repair J Orthop Res 2012 doi: 10.1002/jor.22188
Chen SH, Wang XL, Xie XH, Zheng LZ, Yao D, Wang DP, Leng Y, Zhang G, Qin L* Comparative study on osteogenic potential of a composite scaffold incorporating either endogenous bone morphogenetic protein-2 or exogenous phytomolecule icaritin-an in vitro efficacy study Acta Biomater 2012 8(8):3128-37
Lin X, Peng P, Cheng L, Chen SH, Li K, Li ZY, Mo YH, Zhou Z, Li M* A natural compound induced cardiogenic differentiation of endogenous MSCs for repair of infarcted heart Differentiation 2012 83(1):1-9
Yao D, Xie XH, Wang XL, Wan C, Lee YW, Chen SH, Pei DQ, Wang YX, Li G, Qin L* Icaritin, an Exogenous Phytomolecule, Promotes Osteogenesis but not Angiogenesis-An In Vitro Efficacy Study PLoS One 2012 7(8):e41264
Cheng L, Chen H, Yao X, Qi G, Liu H, Lee K, Lee K, Zhang J, Chen SH, Lin X, Zhao W, Li J, Li M* A Plant-Derived Remedy for Repair of Infarcted Heart PLoS One 2009 4(2):e4461