导师姓名： 李毅刚 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属新华医院 三级学科/
专业领域： 心血管病
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 、
邮编： 200092 邮箱地址： liyigang@xinhuamed.com.cn

研究方向 (点击浏览详细信息)
心律失常的基础与临床研究，心脏电、结构重构，心脏介入诊疗

社会任职
国际动态心电图与无创心电学会理事（ISHNE）
美国心脏节律学会委员（FHRS）
中国心血管健康联盟“无线精准EP沙龙”主任委员
美国心脏病学会委员（FACC）
中国医师学会心血管委员会常委
欧洲心脏病学会委员（FESC）
上海交通大学心律失常诊治中心主任
上海市杨浦区政协委员
中国医疗保健国际交流促进会心律与心电分会副主任委员
中国生物医学工程学会心律分会副主任委员
中国心脏联盟晕厥学会副主任委员
上海市欧美同学会杨浦分会副会长
美国明尼苏达大学心律失常中心客座教授
奥地利格拉茨医科大学学术委员会评审专家（Medical University of Graz, Austria, 2017）
中华医学会心电生理和起搏分会常务委员
上海交通大学医学院知联会副主席
欧洲心脏节律学会委员（FEHRA）
美国哈佛大学医学院高级职称评审专家（The Faculty of Medicine, Harvard University 2018）
中华医学会心血管病学分会委员
上海市生物医学工程学会心律分会副主任委员
中华医学会起搏与电生理分会常委
上海市房颤中心联盟主席
波兰国家科学院项目评审专家（National Science Center Poland 2020）
上海市卒中学会副理事长
上海交通大学医学院附属新华医院心血管内科科主任
上海交通大学医学院医学信息远程监护中心-远程心电诊断中心学科带头人
上海市医学会心血管病分会副主任委员（2008-2019）

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
0 斑马鱼病态窦房结综合征模型的构建及应用 市科委 2020-06~2023-06 20万元 课题负责人
XHKJ190207 房颤患者左心耳封堵术后停用阿司匹林的安全性研究 横向 2019-12~2025-12 250万元 课题负责人
TM201911 雾X线三维标测系统可视导引鞘管、穿刺针及房间隔穿刺技术的研 交大医学院 2019-09~2021-09 8万元 课题负责人
** 体表无创口环肺静脉立体定向放射消融在房颤治疗中的应用研究 上海市科委 2019-03~2022-03 20万元 课题负责人
2018DGDGJJL02 病态窦房结综合征的新致病基因和DNAJB6（L)作为潜在治疗靶点的分子机制的筛选系统的建立 上海交通大学医学院 2018-10~2019-09 15万元 课题负责人
JZPI201706 视黄醇类X受体a在蒽环类药物诱导心脏毒性中的 遗传机制研究（师咏勇） 新华医院 2017-07~2018-06 80万元 课题负责人
16CR2019A 螺内酯对肥厚型心肌病治疗作用的多中心随机对照研究 上海申康医院发展中心 2016-01~2018-12 80万元 课题负责人
** 内源性CaMK II活性抑制因子在心梗修复期室性心律失常中的作用及机制研究 国家自然科学基金重点项目 2016-01~2020-12 273万元 课题负责人
无 心血管内科-市级后备重点学科 学科 2015-08~2016-08 50万元 课题负责人
** 用于房颤治疗的多极消融导管及设备的动物实验研究 上海市科委 2014-07~2017-09 15万元 课题负责人
2014XH012 稳心颗粒对不同机制的自发性和诱发性心律失常的治疗作用及量效关系的研究 横向 2014-02~2015-06 30万元 课题负责人
无 校级重点学科 学科 2014-01~2016-01 10万元 课题负责人
** 神经调控刺激的动物模型建立以及对心血管疾病的影响 市科委 2013-07~2015-09 30万元 课题负责人
** 心肌梗死后局部内皮素-1与sema3a相互作用在心脏交感神经重构中的作用 国家自然基金 2013-01~2016-12 72万元 课题负责人
11cxy39 起搏心电图波形过滤系统和远程诊断的研究 市教委 2011-01~2012-12 15万元 课题负责人
** 浦肯野细胞钙通道重塑在心力衰竭后室性心律失常中的作用和机制 国家自然基金委 2010-12~2013-12 33万元 课题负责人
10XD** 成骨骼肌细胞miR206基因敲除移植心肌后对心律失常发生发展的研究 市科委 2010-04~2012-03 40万元 课题负责人
** 神经化学抑制因子Sema3a在心肌梗死后室颤发生发展中的作用及机制 国家自然基金委,面上项目 2009-01~2011-12 33万元 课题负责人
** miR181的siRNA抗缺血心肌成肌细胞移植后心律失常的研究 国家自然基金委,面上项目 2007-01~2009-12 27万元 课题负责人
留学回国人员基金 电解剖系统引导下环静脉线性消融隔离肺静脉治疗心房颤动 国家教委 2006-06~2009-05 2万元 课题负责人
05PJ14063 复杂心律失常的机制和消融治疗研究 上海市科委,浦江人才 2005-12~2007-09 20万元 课题负责人
05G06 干细胞移植对冠心病弥漫性血管病变患者治疗的可行性研究 院级 2005-03~2006-03 3万元 课题负责人
2004YJ01 Carto指导下有明确心电学消融终点的环肺静脉隔离治疗房颤有效性、安全性评价 院级 2005-01~2006-12 2万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Wei Li, Jian Sun, Peng-Pai Zhang, Yi-Gang Li （通讯作者） Catheter ablation of ventricular arrhythmias originating from the para-Hisian region: Safety is foremost. J Cardiovasc Electrophysiol. 2020 31(6):1567-1568.
Mu Chen, Qun-shan Wang, Jian Sun, Peng-Pai Zhang, Wei Li, Bin-Feng Mo, Yi-Gang Li （通讯作者） Early repolarization in the inferior leads after accessory pathway ablation is highly correlated with atrial fibrillation in Wolff–Parkinson–White syndrome. Journal of Cardiology 2020 75(3):323-329.
Mu Chen, Zhi-Quan Wang, Qun-Shan Wang, Jian Sun, Peng-Pai Zhang, Xiang-Fei Feng, Wei Li, Ying Yu, Bo Liu, Bin-Feng Mo, Rui Zhang, Mei Yang, Chang-Qi Gong, Ming-Zhe Zhao, Yi-Chi Yu, Yan Zhao, Qiu-Fen Lu, Yi-Gang Li （通讯作者） One-stop strategy for treatment of atrial fibrillation: feasibility and safety of combining catheter ablation and left atrial appendage closure in a single procedure. Chin Med J (Engl). 2020 133(12):1422-1428.
Chong-Zhe Pei, Bo Liu, Ye-Ting Li, Lu Fang, Yi Zhang, Yi-Gang Li （通讯作者）, Shu Meng MicroRNA-126 protects against vascular injury by promoting homing and maintaining stemness of late outgrowth endothelial progenitor cells. Stem Cell Res Ther 2020 11(1):28
Yi-He Chen, Hui Lin, Qian Wang, Jian-Wen Hou, Zhi-Jie Mao, Yi-Gang Li （通讯作者） Protective role of silibinin against myocardial ischemia/reperfusion injury-induced cardiac dysfunction. Int J Biol Sci. 2020 16(11):1972-1988.
Yi Yu, Qun-Shan Wang, Xi-Fang Wang, Jian Sun, Ling-Wei Yu, Ming Ding, Yi-Gang Li （通讯作者） Diagnostic value of echocardiography on detecting the various types of anomalous origin of the left coronary artery from the pulmonary artery. J Thorac Dis. 2020 12(3):319-328.
Yan Zhao, Xiao Huang, Peng-Pai Zhang, Hu-ihui Bao, Ya-ren Yu, Min Zhao, Rui Gu, Wei Li, Jun Wang, Quan-Fu Xu, Fang-fang Fan, Jian-ping Li, Yan Zhang, Yu Wang, Gen-fu Tang, Ye-feng Cai, Qiang Dong, De-lu Yin, Xiao-shu Cheng, Ming-li He, Bin-yan Wang, Xian-hui Qin, Yong Huo and Yi-Gang Li Electrocardiographic-left ventricular hypertrophy and incident stroke among Chinese hypertensive adults. J Hum Hypertens. 2020 34(4):286-292
Bin-Feng Mo, Jian Sun, Peng-Pai Zhang, Wei Li, Mu Chen, Jia-Li Yuan, Yi Yu, Qun-Shan Wang, Yi-Gang Li （通讯作者） Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study. J Interv Cardiol. 2020 Jun 25;2020:**. doi: 10.1155/2020/**.
Mei Yang, Run-ze Zhou, Xiang-jun Qiu, Xiang-fei Feng, Jian Sun, Qun-shan Wang, Qiu-fen Lu, Peng-pai Zhang, Bo Liu, Wei Li, Mu Chen, Yan Zhao, Bin-feng Mo, Xin Zhou, Xi Zhang, Ying-xue Hua, Jin Guo, Fang-fang Bi, Ya-jun Cao, Feng Ling, Sheng-ming Shi, Yi-Gang Li （通讯作者） Artificial intelligence-assisted analysis on the association between exposure to ambient fine particulate matter and incidence of arrhythmias in outpatients of Shanghai community hospitals Environ Int. 2020 Jun;139:105745. doi: 10.1016/j.envint.2020.105745.
Wei Li, Jian Sun, Peng-Pai Zhang, Yi-Gang Li （通讯作者） Catheter ablation of ventricular arrhythmias originating from the para-Hisian region: Safety is foremost. J Cardiovasc Electrophysiol. 2020 31(6):1567-1568.
Bin-Feng Mo, Ying Yu , Qun-Shan Wang, Yi-Gang Li （通讯作者） Deformation of left pulmonary vein ridge closely resembles device-related thrombus after Watchman implantation. Eur Heart J Cardiovasc Imaging 2020 21(7):819
Bin-Feng Mo, Peng-Pai Zhang, Mu Chen, Qun-Shan Wang, Yi-Gang Li （通讯作者） Complete atrioventricular block caused by pacing from proximal coronary sinus: What is the mechanism? Pacing Clin Electrophysiol 2020 43(3):350-352
Yi-He Chen , Hui Lin , Qian Wang , Jian-Wen Hou , Yi-Gang Li （通讯作者） Efficacy and Safety of Adjunctive Substrate Modification During Pulmonary Vein Isolation for Atrial Fibrillation: A Meta-Analysis. Heart Lung Circ 2020 29(3):422-436
Feng Jiang, Xi Zhang, Ying-Min Lu, Yi-Gang Li , Xin Zhou （通讯作者）, Yao-Sheng Wang Elevated level of miR-17 along with decreased levels of TIMP-1 and IL-6 in plasma associated with the risk of in-stent restenosis. Biosci Trends 2019 13(5):423-429
Xiang-Fei Feng, Ling-Chao Yang, Li-Zhuang Tan and Yi-Gang Li. Risk factor analysis of device-related infections: value of re-sampling method on the real-world imbalanced dataset. BMC Med Inform Decis Mak. 2019 19(1):185-192
Yi-Gang Li （通讯作者）,Chang-Qi Gong,Jian Sun,Qun-Shan Wang,Peng-Pai Zhang,Xiang-Fei Feng,Yi Yu,Yi-Chi Yu,Bin-Er Liang Determinants of postoperative left atrial structural reverse remodeling in patients undergoing combined catheter ablation of atrial fibrillation and left atrial appendage closure procedure. J Cardiovasc Electrophysiol 2019 30:1868-1876
Wei Li, Jian Sun, Ying Yu, Zhi-quan Wang, Peng-pai Zhang, Kai Guo, Man-tian Chen and Yi-gang Li Clinical Features of Post Cardiac Injury Syndrome Following Catheter Ablation of Arrhythmias: Systematic Review and Additional Cases. Heart Lung Circ 2019 28（11）：1689-1696
Xiao-Meng Chen,Kai Guo,Hong Li,Ling-Chao Yang,Qiu-Feng Lu,Ying Yu,Jian-Wen Hou,Yu-Dong Fei,Jian Sun,Jun Wang,Yi-Xue Li,Yi-Gang Li （通讯作者） A novel mutation KCNQ1p.Thr312del is responsible for long QT syndrome type 1. Heart and vessels 2019 34(1)：177-188
Bin-Feng Mo, Yi Wan, Abudushalamu Alimu, Jian Sun, Peng-Pai Zhang, Ying Yu, Mu Chen, Wei Li, Zhi-Quan Wang, Qun-Shan Wang, Yi-Gang Li Image fusion of integrating fluoroscopy into 3D computed tomography in guidance of left atrial appendage closure. Eur Heart J Cardiovasc Imaging 2019 2019 Nov 25
Yu-Dong Fei,Qian Wang,Jian-Wen Hou, Wei Li, Xing-Xing Cai,Yu-Li Yang,Liu-Hui Zhang,Zhi-Xing Wei,Tai-Zhong Chen,Yue-Peng Wang, Yi-Gang Li （通讯作者） Macrophages facilitate post myocardial infarction arrhythmias: roles of gap junction and KCa3.1. Theranostics 2019 9(22): 6396-6411
Shuai Song,Rui Zhang,Wei Cao,Guo-Jian Fang,Yi Yu,Yi Wan,Chuan-Hui Wang,Qun-Shan Wang,Yi-Gang Li Foxm1 is a critical driver of TGF-β-induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter. Journal of Cellular Physiology 2019 234(6):9052-9064
Xing-Xing Cai,Yu-Li Yang,Yi-Chen Shen,Wei Wang,Li Qian,Jing Cai,Run-Min Chi,Yu-Dong Fei,Shun-Xuan Yu,Le Wei,Jian-Wen Hou,Qian Wang,Jian-Guo Zhang,Deng-Bin Wang,Ma-Wei Jiang,Yi-Gang Li （通讯作者） Noninvasive Stereotactic Body Radiotherapy for Renal Denervation in a Swine Model. Journal of the American College of Cardiology 2019 74:1697–1709
Heng Liang , Man-tian Chen , Fang-fei Qi , Lei Shi , Zhen-zhen Duan, Ruoyu Yang 1 , Jin-chao He , Bin Lou , Yi-gang Li （通讯作者）, Qing Yang The proatherosclerotic function of indoleamine 2, 3- dioxygenase 1 in the developmental stage of atherosclerosis. Signal Transduction and Targeted Therapy 2019 4:23
Jian Sun, Qiu-Feng Lu, Yan Zhao, Peng-Pai Zhang, Jun Wang, Qun-Shan Wang, Xiao-Hong Liu and Yi-Gang Li A low-pass filter of 300 Hz improved the detection of pacemaker spike on remote and bedside electrocardiogram. Chinese Medical Journal 2019 132(5):534-541
Shuai Song, Rui Zhang, Bin-feng Mo, Long Chen, Liang Liu, Yi Yu, Wei Cao, Guo-jian Fang, Yi Wan, Yue Gu, Yue-peng Wang, Yi-gang Li （通讯作者）, Ying Yu and Qun-shan Wang. EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation. Journal of Molecular and Cellular Cardiology 2019 135:119-133
Jian Sun, Peng-Pai Zhang, Qun-Shan Wang, Quan-Fu Xu, Zhi-Quan Wang, Ying Yu, Qian Zhou, Ya-Qin Han, Wei Li and Yi-Gang Li Catheter ablation of ventricular arrhythmias originating from the para-Hisian region with reversed C-curve technique. J Cardiovasc Electrophysiol. 2019 30(11):2377-2386
Rui Zhang, Ling-jun Jie, Wei-ying Wu, Zhi-quan Wang, Hai-ying Sun, Guo-sheng Xiao, Yan Wang and Yi-gang Li Comparative study of carvedilol and quinidine for inhibiting hKv4. 3 channel stably expressed in HEK 293 cells. Eur J Pharmacol. 2019 853:74-83
Xiang-Fei Feng, Peng-Pai Zhang, Jian Sun, Qun-Shan Wang and Yi-Gang Li. Feasibility and Safety of Left Atrial Appendage Closure Using the LAmbre Device in Patients with Nonvalvular Atrial Fibrillation with or Without Prior Catheter Ablation A Single Centre Experience. Int Heart J. 2019 60: 63-70
Wei Li,Jian Sun,Ying Yu,Zhi-Quan Wang,Peng-Pai Zhang,Kai Guo,Man-Tian Chen,Yi-Gang Li （通讯作者） Clinical Features of Post Cardiac Injury Syndrome Following Catheter Ablation of Arrhythmias: Systematic Review and Additional Cases. Heart Lung and Circulation 2018 S1443-9506(18)：31899-31907
Mei Yang,Quan-Fu Xu,Bo Liu,Xiu Chen,Yi-Gang Li （通讯作者） Methodological exploration of bone marrow stem cell therapy in acute myocardial infarction – how to achieve greater benefit on cardiac outcomes: A systematic review and meta-analysis. Advances in Clinical and Experimental Medicine 2018 27(1)：21-37
Zhi-Quan Wang,Wei Li,Kai Guo,Yi-Gang Li （通讯作者） Meta-Analysis of Risk of Ventricular Arrhythmias and All-Cause Mortality in Patients With Chronic Total Occlusion of a Coronary Artery and/or Implantable Cardioverter-Defibrillator. AMERICAN JOURNAL OF CARDIOLOGY 2018 121(10)：1149-1154
Xiang-Fei Feng,Mu Chen,Jian Sun,Yi-Gang Li （通讯作者） Development, safety and efficacy of a novel circular-irrigated deca-channel mapping and ablation catheter for pulmonary vein isolation. BMC Cardiovasc Disord 2018 18(1)：168-175
Jian-Wen Hou,Wei Li,Yu-Dong Fei,Yi-He Chen,Qian Wang,Yue-Peng Wang,Yi-Gang Li （通讯作者） I-CaL and I-to mediate rate-dependent repolarization in rabbit atrial myocytes. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY 2018 74(1)：57-67
Xiang-Fei Feng,Peng-Pai Zhang,Jian Sun,Yi-Gang Li （通讯作者） Feasibility and Safety of Left Atrial Appendage Closure Using the LAmbre Device in Patients with Nonvalvular Atrial Fibrillation with or Without Prior Catheter Ablation. Int Heart J 2018 60(1)：63-70
Jian-Wen Hou,Yu-Dong Fei,Wei Li,Yi-He Chen,Qian Wang,Ying Xiao,Yi-Gang Li （通讯作者）,Yue-Peng Wang The transient receptor potential melastatin 4 channel inhibitor 9-phenanthrol modulates cardiac sodium channel. British Journal of Pharmacology 2018 175(23)：4325-4337
Qian Wang, Yi-He Chen,Dao-Liang Zhang,Chang-Yi Chen,Jian-Wen Hou, Yu-Dong Fei, Yue-Peng Wang, Yi-Gang Li （通讯作者） Activin receptor-like kinase 4 haplodeficiency mitigates arrhythmogenic atrial remodeling and vulnerability to atrial fibrillation in a cardiac pathological hypertrophy. Journal of the American Heart Association 2018 7(16):e008842
Yi-He Chen, Hui Lin, Cheng-Long Xie, Jian-Wen Hou, and Yi-Gang Li （通讯作者） Role of adenosine-guided pulmonary vein isolation in patients undergoing catheter ablation for atrial fibrillation: a meta-analysis. Europace 2017 19(4)：552-559
Qian Wang,Ying Yu,Peng-Pai Zhang,Yi-He Chen,Chang-Yi Li,Jie Chen,Yue-Peng Wang,Yi-Gang Li （通讯作者） The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation. Basic Research in Cardiology 2017 112(4)：47-63
Yu-Dong Fei,Wei Li,Jian-Wen Hou,Kai Guo,Xiao-Meng Chen,Yi-He Chen,Qian Wang,Xiao-Lei Xu,Yue-Peng Wang,Yi-Gang Li （通讯作者） Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling. Int J Mol Sci 2017 18(4)：688-698
Wei Li,Ying Yu,Jian-Wen Hou,Zhi-Wen Zhou,Kai Guo,Peng-Pai Zhang,Zhi-Quan Wang,Jian-Hua Yan,Jian Sun,Qing Zhou,Yue-Peng Wang,Yi-Gang Li （通讯作者） Larger rate dependence of late sodium current in cardiac Purkinje cells: A potential link to arrhythmogenesis. Heart rhythm 2017 14(3)：422-431
Jing Ren,Quan-Fu Xu,Xiao-Meng Chen,Wei Li,Kai Guo,Yang Zhao,Qian Wang,Zhi-Tao Zhang,Hui-Sheng Peng,Yi-Gang Li （通讯作者） Superaligned Carbon Nanotubes Guide Oriented Cell Growth and Promote Electrophysiological Homogeneity for Synthetic Cardiac Tissues. Advanced Materials, 2017 29(44). doi：10.1002/adma.
Qing Zhou,Si-Si Wei,Hong Wang,Qian Wang,Wei Li,Gang Li,Jian-Wen Hou,Xiao-Meng Chen,Jie Chen,Wei-Ping Xu,Yi-Gang Li （通讯作者）,Yue-Peng Wang Crucial Role of ROCK2-Mediated Phosphorylation and Upregulation ofFHOD3 in the Pathogenesis of Angiotensin II-Induced Cardiac Hypertrophy. Hypertension 2017 69(6)：1070-1083
Yao-Sheng Wang,Guang-Yu Chen,Xue-Hai Li,Xin Zhou,Yi-Gang Li （通讯作者） Prolonged P-wave duration is associated with atrial fibrillation recurrence after radiofrequency catheter ablation: A systematic review and meta-analysis. International journal of cardiology. 2017 227:355-359
Yi-He Chen,Qian Wang,Chang-Yi Li, Jian-Wen Hou,Xiao-Meng Chen,Qing Zhou, Jie Chen, Yue-Peng Wang, Yi-Gang Li （通讯作者） Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function. Journal Of Molecular And Cellular Cardiology 2017 4（105）: 1-11
Yi-He Chen, Zhao-Yang Lu, Yin-Xiang, Jian-Wen Hou, Qian-Wang, Hui Lin, Yi-Gang Li （通讯作者） Cryoablation vs. radiofrequency ablation for treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. Europace 2017 19(5)：784-794
Hui Lin, Yi-He Chen, Jian-Wen Hou, Zhao-Yang Lu,Yin Xiang,Yi-Gang Li （通讯作者） Role of contact force-guided radiofrequency catheter ablation for treatment of atrial fibrillation: A systematic review and meta-analysis. J Cardiovasc Electrophysiol 2017 28(9)：994-1005
Yan-Yan Li, Song Zhang, Yi-Gang Li, Yan Wang Isolation, culture, purification and ultrastructural investigation of cardiac telocytes. MOLECULAR MEDICINE REPORTS 2016 14(2)：1194-1200
Chang-Yi Li,Qing Zhou,Ling-Chao Yang,Yi-He Chen,Jian-Wen Hou,Kai Guo,Yue-Peng Wang,Yi-Gang Li （通讯作者） Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway. Basic Res Cardiol 2016 111(2)：19. doi: 10.1007/s00395-016-0536-7
Zhi-Quan Wang,Man-Tian Chen,Rui Zhang,Yi Zhang,Wei Li,Yi-Gang Li （通讯作者） Docosahexaenoic Acid Attenuates Doxorubicin-induced Cytotoxicity and Inflammation by Suppressing. J Cardiovasc Pharmacol 2016 67(4)：283-289
Gang Li, Li Ying, Hong Wang, Si-Si Wei, Jie Chen, Yi-He Chen, Wei-Ping Xu, Qi-Qiang Jie, Qing Zhou, Yi-Gang Li （通讯作者）, Yi-Dong Wei,Yue-Peng Wang Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways1. Oncotarget 2016 7(14):17970-17985
Jie Chen,Hong Wang,,Wei-Ping Xu,,Si-Si Wei,Hui Joyce Li （通讯作者）,Yun-Qing Mei,Yi-Gang Li,Yue-Peng Wang Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcjum-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells. Oncotarget 2016 7(35)：56129-56146
Ying Yu,Linda Ye,Yi-Gang Li （通讯作者）,Dean J. Burkinc,Dayue Darrel Duan Heart-specific overexpression of the human short CLC-3 chloride channel isoform limits myocardial ischemia-induced ERP and QT prolongation. International Journal of Cardiology 2016 214：218-24
Ji-Fang Ma, Fan Yang, Saagar N. Mahida, Ling Zhao, Xiaomin Chen,Michael L. Zhang, Zhijun Sun, Yan Yao, Yi-Xin Zhang,Gu-Yan Zheng, Jie Dong,Ming-Jun Feng, Rui Zhang, Jian Sun, Shuo Li, Qun-ShanWang, Huiqing Cao,Emelia J. Benjamin, Patrick T. Ellinor, Yi-Gang Li （通讯作者）, and Xiao-Li Tian TBX5 mutations contribute to early-onset atrial fibrillation in Chinese and Caucasians. Cardiovascular Research 2016 109(3)：442-450
Ling-Chao Yang, Peng-Pai Zhang, Xiao-Meng Chen, Chang-Yi Li, Jian Sun,Jian-Wen Hou, Ren-Hua Chen, Yue-Peng Wang, and Yi-Gang Li （通讯作者） Semaphorin3a transfection into the left stellate ganglion reduces susceptibility toventricular arrhythmias after myocardial infarction in rats. Europace 2016 18：1886–1896
Mu Chen, Xiang-Fei Feng, Jian Sun, Qun-Shan Wang, Peng-Pai Zhang, Jun Wang, Yi-Gang Li （通讯作者） Risk factors responsible for atrial fibrillation development between symptomatic patients with concealed or manifest atrioventricular accessory pathways. IJC Heart & Vasculature 2015 7：69–75
Qun-Shan Wang,Xiao-Feng Hu,Shu-Yuan Li,Xiao-Feng Wang,Jun Wang,Rui Zhang,Jian Sun,Peng-Pai Zhang,Xiang-Fei Feng,Yi-Gang Li （通讯作者） Association of the angiotensinogen M235T polymorphism with recurrence after catheter ablation of acquired atrial fibrillation. J RENIN-ANGIO-ALDO S 2015 16(4)：888-97
Yao-Sheng Wang,Jing Zhou,Kui Hong,Xiao-Shu Chen,Yi-Gang Li （通讯作者） MicroRNA-223 Displays a Protective Role Against Cardiomyocyte Hypertrophy by Targeting Cardiac Troponin I-Interacting Kinase. Cell Physiology and Biochemistry 2015 35(4)：1546-1556
Yong Tang,Ya-Chen Zhang,Yu Chen,Yin Xiang,Cheng-Xing Shen,Yi-Gang Li The role of miR-19b in the inhibition of endothelial cell apoptosis and its relationship with coronary artery disease. Scientific Reports 2015 5：15132. doi: 10.1038/srep15132
Chang-Yi Li,Ling-Chao Yang,Kai Guo,Yue-Peng Wang,Yi-Gang Li （通讯作者） Mitogen-activated protrin kinase phosphatase-1: A critical phosphatase manipulating mitogen-activated protein kinase signaling in cardiovascular disease. INT J MOL MED 2015 35(4)：1095-102
Yi-He Chen,Hui Lin,Cheng-Long Xie,Xiao-Ting Zhang,Yi-Gang Li （通讯作者） Efficacy comparison between cryoablation and radiofrequency ablation for patients with cavotricuspid valve isthmus dependent atrial flutter: a metaanalysis. Scientific Reports 2015 5:10910. doi: 10.1038/srep10910
Zhi-Quan Wang,Rui Zhang,Peng-Pai Zhang,Xiao-Hong Liu,Jian Sun,Jun Wang,Xiang-Fei Feng,Qiu-Fen Lu,Yi-Gang Li （通讯作者） Pharmacogenetics-based warfarin dosing algorithm decreases time to stable anticoagulation and the risk of major hemorrhage: an updated meta-analysis of randomized controlled trials. J Cardiovasc Pharmacol. 2015 65(4)：364-370
Jian-Wen Hou,Wei Li,Kai Guo,Xiao-Meng Chen,Yi-He Chen,Chang-Yi Li,Bu-Chang Zhao,Jing Zhao,Hong Wang,Yue-Peng Wang,Yi-Gang Li （通讯作者） Antiarrhythmic effects and potential mechanism of WenXin KeLi in cardiac Purkinje cells. Heart Rhythm 2015 13(4)：973-82
Yan Zhao,Peng-Pai Zhang,Quan-Fu Xu,Ling-Wei Yu,Yi Yu,Yi-Gang Li （通讯作者） Relationship between left atrial appendage morphology and thrombus formation in patients with atrial fibrillation. International journal of cardiology 2015 188：86-88
Wei Li,Jian Sun,Ying Yu,Kai Guo,,Qun-Shan Wang,Peng-Pai Zhang,Qing Zhou （通讯作者）,Yi-Gang Li What is the role of left bundle branch block in atrial fibrillation-induced cardiomyopathy? International Journal of Cardiology 2015 184：382-384
Ying-gang Sun,Xin-yan Wang,Xiu Chen,Cheng-xing Shen,Yi-gang Li （通讯作者） Hydrogen sulfide improves cardiomyocytes electrical remodeling post ischemia/reperfusion injury in rats. nt J Clin Exp Pathol 2015 8(1)：474-481
Bo Liu,Yi-Gang Li （通讯作者） Impact of Conditional miRNA126 Overexpression on Apoptosis-Resistant Endothelial Cell Production. PLOS ONE 2015 10(5)：e**
Yu-Quan Xie,Chang-Yi Li,Liang Bo,Shuo Jiang,Hai-Dong Kan,Wei-Xin Song,Jin-Zhou Zhao,Yi-Gang Li （通讯作者） Treg responses are associated with PM2.5-induced exacerbation of viral myocarditis. Informa healthcare 2015 27(6)：281-286
Kai Guo,Yue-Peng Wang,Zhi-Wen Zhou,Yi-Bo Jiang,Wei Li,Xiao-Meng Chen,Yi-Gang Li （通讯作者） Impact of phosphomimetic and non-phosphorylatable mutations of phospholemman on L-type calcium channels gating in HEK 293T cells. Journal of Cellular and Molecular Medicine 2015 19(3)：642-650
Ling-Chao Yang,Peng-Pai Zhang,Xiao-Meng Chen,Chang-Yi Li,Jian Sun,Jian-Wen Hou,,Ren-Hua Chen,Yue-Peng Wang （通讯作者）,Yi-Gang Li Semaphorin 3a transfection into the left stellate ganglion reduces susceptibility to ventricular arrhythmias after myocardial infarction in rats. Europace 2015 18(12)：1886-1896
Li Ying,Gang Li,Si-si Wei,,Hong Wang,Pei An,Xun Wang,Kai Guo,Xian-jin Luo,Ji-min Gao,Qing Zhou,,Wei Li （通讯作者）,Ying Yu,,Yi-gang Li,Jun-li Duan,Yue-peng Wang Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation. Original Article 2015 36(2)：229-240
Zhi-Quan Wang,Rui Zhang,,Man-Tian Chen,,Qun-Shan Wang,Yi-Zhang,Xiao-Hong Huang,Jun Wang （通讯作者）,Jian-Hua Yan,Yi-Gang Li Digoxin Is Associated With Increased All-cause Mortality in Patients With Atrial Fibrillation Regardless of Concomitant Heart Failure: A Meta-analysis. J Cardiovasc Pharmacol. 2015 66(3)：270-275
Zhi-Wen Zhou,Kai Guo,Zhang-Yuan Luo,Wei Li,Wen-Zan Zhang,Yi-Gang Li （通讯作者） Feasibility and efficacy of a remote real-time wireless ECG monitoring and stimulation system for management of ventricular arrhythmia in rabbits with myocardial infarction. Experimental and Therapeutic Medicine 2014 8(1)：201-206
Zhi-Wen Zhou,Bu-Chun Zhang,Yi Yu,Kai Guo,,Wei Li,Rui Zhang,Peng-Pai Zhang （通讯作者）,,Yi-Gang Li Acute Impact of Pacing at Different Cardiac Sites on Left Ventricular Rotation and Twist in Dogs. PLoS ONE 2014 9(10)：e111231
Quan-Fu Xu,Shu Meng,Bo Liu, Mao-Quan Li, Ye-Ting Li, Lu Fang, Yi-Gang Li （通讯作者） MicroRNA-130a regulates autophagy of endothelial progenitor cells though Runx3. Clinical and Experimental Pharmacology and physiology 2014 41(5)：351-357
Song Zhang,Mei-Qi Zhang,Steven Goldstein,Yi-Yang Li,Jun-Bo Ge,Ben He,George Ruiz The Effect of c-fos on Acute Myocardial Infarction and the Significance of Metoprolol Intervention in a Rat Model. Cell Biochem Biophys 2013 65(2)：249-255
Song Zhang,Xin Liu,Steven Goldstein,Yi-Gang Li,Jun-BO Ge, Ben He,Xue-Tao Fei,Zu-Yue Wang,George Ruiz. Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-ΚB expression. molecular medicine reports 2013 7(1)：93-98
Ren-Hua Chen,Yi-Gang Li （通讯作者）,Kun-Li Jiao,Peng-Pai Zhang,Yu Sun,Li-Ping Zhang,Xiang-Fei Fong,Wei Li,Yi Yu Overexpression of Sema3a in myocardial infarction border zone decreases vulnerability of ventricular tachycardia post-myocardial infarction in rats. J.Cell.Mol.Med 2013 17(5)：608-616
Shu Meng,Jia-Tian Cao,Xiao-Ping Zhang,Yu-Qi Fan,Lu Fang,Chang-Qian Wang,Zhong-Wei Lv,Da Fu,Yi-Gang Li （通讯作者） Downregulation of MicroRNA-130a Contributes to Endothelial Progenitor Cell Dysfunction in Diabetic Patients via Its Target Runx3. PLOS ONE 2013 8(7)：e68611
Xue-Tao Fei,Shan Jiang,Song Zhang,Yi-Gang Li,Jun-Bo Ge,Ben He,Steven Goldstein,George Ruiz Isolation, culture, and identification of amniotic fluid-derived mesenchymal stem cells. Cell Biochemistry and Biophysics 2013 67(2)：689-694
Wei Li,Yue-Peng Wang,Ling Gao,Peng-Pai Zhang,Qing Zhou,Quan-Fu Xu,Zhi-Wen Zhou,Kai Guo,Ren-Hua Chen,Huang-Tian Yan,Yi-Gang Li （通讯作者） Resveratrol protects rabbit Ventricular myocytes against oxidative stress-induced arrhythmogenic activity and Ca2+ overload. Acta Pharmacologica Sinica 2013 34(9)：1164-73
Kun-Li Jiao, Yi-Gang Li （通讯作者）,Peng-Pai Zhang,Ren-Hua Chen,Yi Yu Effects of valsartan on ventricular arrhythmia induced by programmed electrical stimulation in rats with myocardial infarction. J Cell Mol Med. 2012 16(6)：1342-1351
Zhi-Wen Zhou,Bu-Chun Zhang,Yi Yu,Kai Guo,Wei Li,Rui Zhang,Peng-Pai Zhang,Yi-Gang Li （通讯作者） Acute Impact of Pacing at Different Cardiac Sites on Left Ventricular Rotation and Twist in Dogs. PLoS ONE 2012 9(10)：e111231
Yi-Gang Li,Mei Yang,Yu-Hua Li,Qun-Shan Wang,Lin-Wei Yu,Jian Sun Spatial relationship between left atrial roof or superior pulmonary veins and bronchi or pulmonary arteries by dual-source computed tomography: implication for preventing injury of bronchi and pulmonary arteries during atrial fibrillation ablation. Europace 2011 13(6)：809-814
Shu-Yan Chen,Fei Wang,Xue-Yun Yan,Qing Zhou,Qiang Ling,Ji-Xian Ling,Ye-Zhi Rong,Yi-Gang Li （通讯作者） Autologous transplantation of EPCs encoding FGF1 gene promotes neovascularization in a porcine model of chronic myocardial ischemia. Int J Cardiol 2009 135(2)：223-32
Yi-Gang Li,Peng-Pai Zhang,Kun-Li Jiao,Yun-Zeng Zou Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction. Microvasc Res 2009 78(3)：393-404
Xiao-Jing Sun,Tiffany Hoage,Ping Bai,Yong-He Ding,Zhen-Yue Chen,Rui-Lin Zhang,Wei Huang,Ashad Jahangir,Barry Paw,Yi-Gang Li （通讯作者）,Xiao-Lei Xu Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish. PLoS One 2009 4(8)：e6596
Qun-Shan Wang,Xiao-Feng Wang,Xing-Dong Chen,Jie-Fei Yu,Jun Wang,Jian Sun,Shang-Biao Lu,Mu-Yao Shen,Ming Lu,Yi-Gang Li （通讯作者）,Li Jin Genetic Polymorphism of KCNH2 Confers Predisposition of Acquired Atrial Fibrillation in Chinese. J Cardiovasc Electrophysiol 2009 20(10)：1158-1162
Yi-Gang Li,Qun-Shan Wang,CARSTEN W. ISRAEL,GERIAN GRO¨ NEFELD,Shang-Biao Lu,JOACHIM R. EHRLICH, STEFAN H. HOHNLOSER Quantitative Analysis of the Duration of Slow Conduction in the Reentrant Circuit of Ventricular Tachycardia after Myocardial Infarction. J Cardiovasc Electrophysiol 2008 19(9)：920-927
Yi-Gang Li,WANG Q,Gr?nefeld G,Israel C,LU S,Shao Y,Ehrlich JR,Stefan H. Hohnloser Refinement of CARTO-Guided Substrate Modification in Patients With Ventricular Tachycardia after Myocardial Infarction. Chinese Medical Journal 2008 121(2)：122-127
Yi-Gang Li,Gerian Gr?nefeld,Carsten Israel,Shang-Biao Lu,Qun-Shan Wang,Stefan H Hohnloser Radiofrequency catheter ablation in patients with symptomatic atrial flutter/tachycardia after orthotopic heart transplantation. Chinese Medical Journal 2006 119(24)：2036-2041
Yi-Gang Li （共同第一作者）,Gr?nefeld G,Israel C,LU S,WANG Q,MENG S,Hohnloser SH Stepwise approach to substrate modification of ventricular tachycardia after myocardial infarction. Chinese Medical Journal 2006 119(14)：1182-1189
Yi-Gang Li,Groenefeld G,Israel C,Hohnloser SH Catheter Ablation of Frequently Recurring Ventricular Fibrillation in a Patient after Aortic Valve Repair. J Cardiovasc Electrophysiol 2004 15(1)：90-93
Yi-Gang Li （共同第一作者）,Groenefeld G,Israel C,Hohnloser SH Bundle-Branch Reentrant Tachycardia in Patients with Apparent Normal His-Purkinje Conduction: the Role of Functional Conduction Impairment. J Cardiovasc Electrophysiol 2002 13(12)：1233-1239