导师姓名： 段俊丽 专业代码： 100201
性别： 女 专业名称： 内科学
培养单位： 附属新华医院 三级学科/
专业领域： 心血管病
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： 邮箱地址： junlishanghai2005@yahoo.com.cn

研究方向 (点击浏览详细信息)
缺血性心脏病的血管新生疗法



社会任职
中华医学会中西医分会高血压学会委员
中华医学会老年医学分会基础学组委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
YG2019ZDA21 超声相控阵智能模拟针刺手法系统 上海交通大学“交大之星”计划医工交叉研究基金 2020-01~2022-12 100万元 课题负责人
** 超声相控阵模拟针刺手法对脑梗死后遗症肢体活动障碍改善的疗效研究 上海市科学技术委员会医学引导类（中、西医）科技支撑项目 2018-09~2021-09 25万元 课题负责人
** “健康样”血管新生的超声干预与光声评估方法研究 国家自然科学基金面上项目 2018-01~2021-12 65万元 课题负责人
** 利用光谱移动效应对动脉硬化早期诊断的研究 国家自然科学基金 2016-01~2019-10 75万元 课题负责人
15LC18 低强度连续超声波辅助治疗下肢动脉硬化闭塞症的临床研究 院基金 2016-01~2018-01 6万元 课题负责人
** 单细胞内药物分布的扫描探针研究 国家自然科学基金 2014-01~2017-12 90万元 课题负责人
11nm** 磷酸钙纳米载体负载Ang-VEGF双基因用于治疗性血管新生研究 上海市科学技术委员会科研计划项目纳米专项资助 2011-10~2014-09 60万元 课题负责人
09JC** 计算机辅助血压、血糖动态特性与心血管疾病关联性的研究 上海市科委"创新行动计划"基础研究重点项目 2009-09~2011-08 30万元 课题负责人
胆碱能抗炎机制在限制热量摄入延缓脑梗死发生中的作用研究 上海交通大学医工合作专项 2009-06~2011-05 5万元 课题负责人
2009CB521900 脑血管疾病发生和防治的基础研究 973项目课题中承担其中一部分 2009-01~2014-12 60万元 主要责任人
08ZR** 凝聚态物理学方法对血压波动在老年血管损伤现象的研究 上海市科委，自然科学基金 ~2010-09 10万元

学术论文 作者论文标题期刊名出版年卷期页码
Xue-Lian Wang, Jia Qi1, Yi-Qin Shi, Zhao-Yang Lu, Rui-Lin Li, Gao-Jian Huang, Bing-Bing Ning,Liang-Shi Hao, Huan Wang, Chang-Ning Hao, Yue Li, Hong-Sheng Zhou, Jun-Li Duan （通讯作者） Atorvastatin plus therapeutic ultrasound improve postnatal neovascularization in response to hindlimb ischemia via the PI3K-Akt pathway Am J Transl Res 2019 11(5):2877-2886
Zhi-Xiao Su,Yi-Qin Shi,Zhao-Yang Lu, Rui-Lin Li, Xue-Lian Wang, Bing-Bing Ning, Jun-Li Duan, Liang-Shi Hao, Jun-Hui Duan, Yue Li, Ying-Jie Zhu, Chang-Ning Hao, Rui Wang Comparative study of nanostructured carriers of calcium phosphate and magnesium phosphate loaded with SRT1720 for the protection of H2O2-induced senescent endothelium. Am J Transl Res 2018 10(7): 2068–2077
Jia Qi, Feng Wang, Ping Yang,Xuelian Wang, Renjie Xu, Jihui Chen, Yanggang Yuan, Zhaoyang Lu, Junli Duan （通讯作者） Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway Front Pharmacol. 2018 9:176
Lu ZY, Zhou HS, Su ZX, Qi J, Zhang J, Xue GH, Li Y, Hao CN, Shi YQ ,Duan JL （通讯作者） Therapeutic ultrasound plus pulsed electromagnetic field improves recovery from peripheral arterial disease in hypertension. Am J Transl Res 2017 9: 4184-4194
An Hu,Jing-Juan Huang,Jing-Fei Zhang,Wei-Jun Dai,Rui-Lin Li,Zhao-Yang Lu,Jun-Li Duan,Ji-Ping Li, Xiao-Ping Chen,Jing-Ping Fan,Wei-Hua Xu,Hong-Liang Zheng Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53-dependent pathway Oncotarget 2017 8:50747-50760
Huang JJ, Shi YQ, Li RL, Hu A, Lu ZY, Weng L, Han YP, Wang SQ, Zhang L, Hao CN , Duan JL （通讯作者） Therapeutic ultrasound protects HUVECs from ischemia/hypoxia-induced apoptosis via the PI3K-Akt pathway. Am J Transl Res 2017 9: 1990-1999
Qi J,Wang JJ, Duan JL （通讯作者）, Lu ZY, Yuan YG Leonurine Improves Age-Dependent Impaired Angiogenesis: Possible Involvement of Mitochondrial Function and HIF-1α Dependent VEGF Activation Front Pharmacol. 2017 :284
Lu ZY, Li RL, Zhou HS, Huang JJ, Qi J, Su ZX, Zhang L, Li Y, Shi YQ, Hao CN, Duan JL. （通讯作者） Rescue of hypertension-related impairment of angiogenesis by therapeutic ultrasound Am J Transl Res 2016 8(7):3087-3096
Li RL, Lu ZY,Huang JJ, Qi J, Hu A, Su ZX, Zhang L, Shi YQ, Hao CN, Duan JL （通讯作者） SRT1720, a SIRT1 specific activator, protected H2O2-induced senescent endothelium Am J Transl Res 2016 8(7):2876-2888
An Hu, Jing-Juan Huang, Rui-Lin Li, Zhao-Yang Lu, Jun-Li Duan （通讯作者）, Wei-Hua Xu,Xiao-Ping Chen,Jing-Ping Fan Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1 Sci Rep 2015 5:13429. doi: 10.1038/srep13429
An Hu, Jing-Juan Huang, Wei-Hua Xu, Xiao-Jie Jin, Ji-Ping Li, Yuan-Jia Tang, Xin-Fang Huang, Hui-JuanCui, Guang-Bin Sun, Rui-Lin Li, Jun-Li Duan （通讯作者） MiR-21/miR-375 ratio is an independent prognostic factor in patients with laryngeal squamous cell carcinoma Am J Cancer Res 2015 5(5):1775-1785
Wei-Ming Wang, Zhao Liu,Ai-Jun Liu,Yu-Xiang Wang,Hong-Gang Wang, Di An,Bin Heng,Lai-Hua Xie,Jun-Li Duan （通讯作者）,Yan-Qiang Liu The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation CNS Neuroscience & Therapeutics 2015 21(9):708-717
Li YING, Gang LI, Si-si WEI, Hong WANG1, An PEI, Xun WANG, Kai GUO, Xian-jin LUO, Ji-min GAO, Qing ZHOU, WeiLI, Ying YU, Yi-gang LI, Jun-li DUAN （通讯作者）, Yue-peng WANG Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation Acta Pharmacologica Sinica 2015 36(2):229-240
Jing-Juan Huang, Yi-Qin Shi, Rui-Lin Li, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang, Bao Li, Chang-Ning Hao, Jun-Li Duan （通讯作者） Angiogenesis effect of therapeutic ultrasound on HUVECs through activation of the PI3K-Akt-eNOS signal pathway Am J Transl Res 2015 7(6):1106-1115
Rui-Lin Li, Jing-Juan Huang, Yi-Qin Shi, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang, Chang-Ning Hao, Jun-Li Duan （通讯作者） Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia Am J Transl Res 2015 7(3):430-444
Huang ZY, Xiong DY, Zhang GX, Shi YQ, Hao CN, Duan JL （通讯作者） Nonnegative Matrix Factorization Numerical Method for Integrated Photonic Cavity Based Spectroscopy Hindawi Publishing Corporation Journal of Nanomaterials 2014 310601, 1-5
Hao CN, Huang ZH, Song SW, Shi YQ, Cheng XW , Lu W, Su DF, Duan JL （通讯作者） Arterial Baroreflex Dysfunction Impairs Angiogenesis: A Murine Model of Hindlimb Ischemia J Am Heart Assoc. 2014 3:e000804 doi: 10.1161
Chao Qi,Jing-Juan Huang,Feng Chen,Jin Wu, Chang-Ning Hao, Yi-Qin Shi,Jun-Li Duan （通讯作者）,Ying-Jie Zhu Synthesis, characterization and applications of calcium carbonate/fructose 1,6-bisphosphate composite nanospheres and carbonated hydroxyapatite porous nanospheres J. Mater. Chem. B 2014 2(47). DOI: 10.1039/C4TB01342E
Hao CN, Huang JJ, Shi YQ, Li HY, Guo XG, Cheng XW,Li RL, Lu W, Zhu YZ,Duan JL （通讯作者） Pulsed Electromagnetic Field Improves Cardiac Function in Response to Myocardial Infarction Am J Transl Res 2014 6(3):281-290
Jing-Juan Huang,Yi-Qin Shi, Rui-Lin Li, An Hu, Hong-Sheng Zhou, Qian Cheng, Zheng Xu, Zhi-MingYang, Chang-Ning Hao, Jun-Li Duan （通讯作者） Angiogenesis effect of therapeutic ultrasound on ischemic hind limb in mice Am J Transl Res 2014 6(6):703-713
Guo JM, Liu AJ, Zang P, Dong WZ, Ying L, Wang W, Xu P, Song XR, Cai J, Zhang SQ, Duan JL, Mehta JL, Su DF ALDH2 protects against stroke by clearing 4-HNE Cell Res 2013 23:915-30
Sun Y, Gui H, Li Q, Luo ZM, Zheng MJ, Duan JL （通讯作者）, Liu X MicroRNA-124 protects neurons against apoptosis in cerebral ischemic stroke CNS Neurosci Ther 2013 19 :813-9.
Huang ZH, Guo W, Zhang LL, Song SW, Hao CN, Duan JL （通讯作者） Donepezil Protect Endothelial Cells against Hydrogen Peroxide Induced Cell Injury CNS Neuroscience & Therapeutics 2012 18:185-7
Hao CN, Geng YJ, Li F, Yang T, Su DF, Duan JL （通讯作者）,Li Y Insulin-like growth factor-1 receptor activation prevents hydrogen peroxide-induced oxidative stress, mitochondrial dysfunction and apoptosis. Apoptosis Apoptosis 2011 16: 1118-27
Ma K, Liu Y, Zhu Q, Liu CH, Duan JL,Tan BK, Zhu YZ H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S? PLoS One 2011 6:1-7
Hao CN, Huang ZH, Shi YQ, Lu W, Duan JL （通讯作者） A New Index to Predict the Incidence of Cerebral Infarction CNS Neuroscience & Therapeutics. 2011 17:783-4
Huang ZH, Hao CN, Zhang LL, Huang YC, Shi YQ, Jiang GR, Duan JL （通讯作者） Non-invasive blood glucose sensing on human body with near-infrared reflection spectroscopy Interational Symposium on Photoelectronic Detection and Imaging 2011 8193: 1-10
Song SW, Liu AJ, Bai B, Ma XJ, Shen FM, Duan JL （通讯作者）,Su DF Blood pressure reduction combining baroreflex restoration for stroke prevention in hypertension in rats Original Research Article 2010 30:1–7
Duan JL （通讯作者）,Hao CN, Lu W, Han L, Pan ZH, Gu Y, Liu BJ, Tao R, Shi YQ, Du YY A new method for assessing variability of 24-h blood pressure and its first application in 1526 elder men Clin Exp Pharmacol Physiol 2009 36: 1093–1098
Li L, Zhao L, Yi-Ming W, Yu YS, Xia CY, Duan JL （通讯作者）, Su DF Sirt1 hyperexpression in SHR heart related to left ventricular hypertrophy Can J Physiol Pharmacol 2009 87: 56-62
Li DJ, Tang Q, Shen FM, Su DF, Duan JL （通讯作者）, X Tao Overexpressed α7 nicotinic acetylcholine receptor inhibited proinflammatory cytokine release in NIH3T3 cells Journal of Bioscience and Bioengineering 2009 108（2）: 85–91
Sasaki K, Duan J （共同第一作者）,Murohara T, Ikeda H, Shintani S, Shimada T, Akita T, K Egami, Imaizumi T Rescue of hyercholesterolemia-related impairment of angiogenesis by oral folate supplementation J Am Coll Cardiol 2003 42(2):364-372
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Duan J （共同第一作者）, Murohara T, Ikeda H, Kotoh A, Kawada H, Yamamoto N, Ueno T, Imaizumi T Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: Nitric oxide-dependent mechanism. circulation 2000 102:370-6
Duan J （共同第一作者）, Murohara T, Ikeda H, Kotoh A, Kawada H, Yamamoto N, Ueno T, Imaizumi T Hyperhomocysteinemia impairs angiogenesis and collateral vessel formation in response to hindlimb ischemia Arterioscler Thromb Vasc Biol. 2000 20:2579-85
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