导师姓名： 张洪梅 专业代码： 100201
性别： 女 专业名称： 内科学
培养单位： 附属新华医院 三级学科/
专业领域： 内分泌与代谢病
导师类型： 硕士生导师 专业学位导师： 兼
联系方式： 上海市控江路1665号新华医院内分泌科
邮编： 200092 邮箱地址： spicygirlss@126.com

研究方向 (点击浏览详细信息)
糖尿病及其并发症的发病机制研究
甲状腺疾病的发病机制

社会任职
中华内分泌代谢杂志通讯编委
上海市医学会糖尿病分会委员
上海市医学会内分泌专科分会甲状腺学组委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2019PJD033 OPG信号通路参与肥胖引起的甲状腺细胞增生机制研究 上海市科委浦江人才计划 2019-11~2021-10 30万元 课题负责人
** 蛋白激酶C参与甲状腺功能减退性鼠脑发育障碍的机制 国家自然基金 2014-01~2016-12 23万元 课题负责人
10ZR** 甲状腺激素调节发育期鼠脑SNAP-25的相关机制研究 上海市自然基金 2010-03~2013-03 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Hongmei Zhang, Li Qin, Chang-Sheng Sheng, Yixin Niu, Hongxia Gu, Shuai Lu, Zhen Yang, Jingyan Tian*, Qing Su* ASCVD risk stratification modifies the effect of HbA1c on cardiovascular events among patients with type 2 diabetes mellitus with basic to moderate risk BMJ Open Diabetes Res Care 2020 8(1):e000810
Shichun Du#, Hongmei Zhang# （共同第一作者）, Hui Wu, Shu Ye, Wen Li, Qing Su Prevalence and Gender Differences of Metabolic Syndrome in Young Ketosis-Prone Type 2 Diabetic Individuals: A Retrospective Study. Diabetes Diabetes Metab Syndr Obes 2020 13:2719-2727
Fan Hu, Yixin Niu, Xiaoyuan Xu, Qiuyue Hu, Qing Su* and Hongmei Zhang* Resistant dextrin improves high-fat-high-fructose diet induced insulin resistance Nutr Metab (Lond) 2020 15;17:36
Hongmei Zhang, Yixin Niu, Hongxia Gu, Shuai Lu, Weiwei Zhang, Xiaoyong Li, Zhen Yang, Li Qin, Qing Su Low serum adiponectin is a predictor of progressing to non-alcoholic fatty liver disease Journal of Clinical Laboratory Analysis 2019 33(3):e22709
Hong-mei ZHANG, Qi-wen FENG1, Yi-xin NIU, Qing SU, Xia WANG Thyroid Nodules in Type 2 Diabetes Mellitus Curr Med Sci 2019 39(4):576-581
Hongmei Zhang, Yixin Niu, Hongxia Gu, Shuai Lu, Weikang Su, Ning Lin, Xiaoyong Li, Zhen Yang, Li Qin, Qing Su The association between white blood cell subtypes and prevalence and incidence of nonalcoholic fatty liver disease European Journal of Inflammation 2019 17:1-6
Zhang H, Niu Y, Gu H, Lu S, Zhang W, Li X, Yang Z, Qin L, Su Q. Low serum adiponectin is a predictor of progressing to non-alcoholic fatty liver disease Journal of Clinical Laboratory Analysis 2018 2018 Nov 2:e22709
Tu X, Dong Y, Zhang H （通讯作者）, Su Q. Corticosteroids for Graves’ Ophthalmopathy BioMed research International 2018 2018:**
屠晓芳,张洪梅 （通讯作者）,苏青 稳定表达全长人促甲状腺激素受体细胞株构建及功能评价 中华内分泌代谢杂志 2018 34(2):154-157
胡帆 钮忆欣 屠晓芳 苏青 张洪梅 抗性糊精通过增强胰岛素信号转导改善 db/db小鼠胰岛素抵抗 上海交通大学学报医学版 2018 Vol. 38 (10): 1157-1161
Hongmei Zhang, Yaqing Zhou, Yan Dong, Qing Su Identification and functional characterization of a novel thyrotropin receptor mutation (V87L) in a Chinese woman with subclinical hypothyroidism Exp Ther Med 2017 13 (1): 290-294
Yinnan Chen, Hongmei Zhang （通讯作者）, Yanmin Zhang Targeting receptor tyrosine kinase EphB4 in cancer therapy Seminars in Cancer Biology 2017 Epub ahead of print
Hongmei Zhang, Weiwei Zhang, Xiaofang Tu, Yixin Niu, Xiaoyong Li, Li Qin, Zhen Yang, Qing Su Elevated serum growth differentiation factor 15 levels are associated with thyroid nodules in type 2 diabetes aged over 60 years Oncotarget 2017 8 (25): 41379-41386
Hongmei Zhang, Zhen Yang, Weiwei Zhang, Yixin Niu, Xiaoyong Li, Li Qin, Qing Su White blood cell subtypes and risk of type 2 diabetes Journal of Diabetes and Its Complications 2017 31: 31-37
Hongmei Zhang, Chonghuai Yan, Zhen Yang, Weiwei Zhang, Yixin Niu, Xiaoyong Li, Li Qin, Qing Su Perinatal hypothyroidism modulates antioxidant defence status in the developing rat liver and heart Can J Physiol Pharmacol 2017 95 (2): 185-189
Hongmei Zhang, Zhen Yang, Weiwei Zhang,Yixin Niu,Xiaoyong Li,Li Qin, Qing Su HIGHER SERUM OSTEOPROTEGERIN LEVELS IN SUBJECTS WITH THYROID NODULES ENDOCRINE PRACTICE 2016 Vol 22 No. 4 (412-419)
Zhen Yang#, Hongmei Zhang# （共同第一作者）, Yixin Niu, Weiwei Zhang, Lingfei Zhu, Xiaoyong Li, Shuai Lu, Jiangao Fan, Xiaoying Li, Guang Ning, Li Qin, Qing Su Circulating periostin in relation to insulin resistance and nonalcoholic fatty liver disease among overweight and obese subjects Sci Rep 2016 6（37886）
张洪梅,张伟伟,李晓永,陈寒蓓,杨震,钮忆欣,苏青 桥本甲状腺炎合并干燥综合征肾小管酸中毒致低钾血症的临诊应对 中华内分泌代谢杂志 2016 Vol. 32, No. 4 (349-352)
Zhuhua Z, Zhiquan W, Zhen Y, Yixin N, Weiwei Z, Xiaoyong L, Yueming L, Hongmei Z, Li Q, Qing S A novel mice model of metabolic syndrome: the high-fat-high-fructose diet-fed ICR mice Exp Anim 2015 64(4):435-42
Zhang W, Yang Z, Li X, Wen J, Zhang H, Wang S, Wang X, Zhou H, Fang W, Qin L,Su Q The functional Q84R polymorphism of TRIB3 gene is associated with diabetic nephropathy in Chinese type 2 diabetic patients Gene 2015 555(2):357-61
Niu Y*, Zhang W*, Yang Z, Li X, Wen J, Wang S, Zhang H, Wang X, Zhou H, Fang W, Qin L, Su Q Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes BMC Cardiovasc Disord 2015 15:86
Kong X, Ma MZ, Huang K, Qin L, Zhang HM, Yang Z, Li XY, Su Q Increased plasma levels of the methylglyoxal in patients with newly diagnosed type 2 diabetes. J Diabetes 2014 6(6):535-540
Zhang HM, Su Q. PKC in developing hypothyroid rat brain Neurol Sci 2014 Epub ahead of print
张洪梅 方文军 胡静芳 苏青 急性甲亢性延髓麻痹的临诊应对 中华内分泌代谢杂志 2014 30(2): 153-155
Zhang HM, Lin N, Dong Y, Su Q, Luo M. Protein kinase cα is involved in impaired perinatal hypothyroid rat brain development. Journal of neuroscience research 2013 92(2): 211-219
Lin N, Chen HB, Zhang HM, Wan XY, Su Q. Mitochondrial ROS inhibition ameliorates endoplasmic reticulum stress in palmitate-induced INS-1 beta cell death Endocrine 2012 42(1):-
Lin N, Zhang HM, Su Q. Advanced glycation end products induce pancreatic beta cell injury through oxidative stress. Diabetes Metab 2012 38(3):-
Zhang HM, Lin N, Dong Y, Su Q, Luo M. Effect of perinatal thyroid hormone deficiency on expression of rat hippocampal conventional protein kinase C isozymes. Mol Cell Biochem 2011 353(1-2): 65-71
Ge QM, Dong Y, ZHANG HM,Su Q. Effects of intermittent high glucose on oxidative stress in endothelial cells. Acta Diabetol 2010 47(1):97-103
张洪梅 苏 青 罗 敏 甲状腺激素缺乏对不同发育时期大鼠脑组织氧化应激指标的影响 吉林大学学报医学版 2010 36(5): 854-856