导师姓名： 芦雪峰 专业代码： 100211
性别： 女 专业名称： 妇产科学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式： 手机：**邮箱：xuefenglu126@126.com邮箱：315018@sh9hospital.org
邮编： 邮箱地址： xuefenglu163@163.com

研究方向 (点击浏览详细信息)
辅助生殖技术

社会任职
上海市医学会生殖医学 青年委员
欧美同学会医师协会青年委员会 常委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
基于雌二醇下降的紧急取卵策略在自然周期中的应用及其治疗效果评估-一项随机对照临床研究 上海市卫生健康委员会 2020-01~2022-12 20万元 课题负责人
** 高孕激素促排卵对子代DNA甲基化修饰的影响及其机理的研究 上海交通大学医学院地高大双**** 2019-10~2022-09 115万元 课题负责人
** 高孕激素促排卵对子代DNA甲基化修饰的影响及其机理的研究 国家自然科学基金委 2019-01~2022-12 85万元 课题负责人
** SIRT6组蛋白去乙酰化激动剂探针设计及其在肝癌中功能研究的应用 国家自然科学基金委 2018-01~2020-12 70万元 子课题负责人
临+计划 低LH患者PPOS促排卵方案加用克罗米芬的疗效评估 上海交通大学医学院附属第九人民医院 2017-09~2020-08 40万元 课题负责人
** 以Nanog转基因小鼠为模型研究多潜能因子Nanog在乳腺癌发生及转移中的作用 国家自然科学基金委 2013-01~2016-12 24万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Xinyi Liu, Shaoyong Lu, Kun Song, Qiancheng Shen, Duan Ni, Qian Li, Xinheng He, Hao Zhang, Qi Wang, Yingyi Chen, Xinyi Li, Jing Wu, Chunquan Sheng, Guoqiang Chen, Yaqin Liu, Xuefeng Lu （通讯作者）, Jian Zhang Unraveling allosteric landscapes of allosterome with ASD Nucleic Acids Res 2020 48 (D1):D394-D401
Shuzin Khor, Qifeng Lyu, Yanping Kuang, Xuefeng Lu （通讯作者） Novel FSHR variants causing female resistant ovary syndrome Mol Genet Genomic Med 2020 8(2):e1082
Xuefeng Lu, Zheng Yan, Renfei Cai et al. Pregnancy and Live Birth In Women With Pathogenic LHCGR Variants Using Their Own Oocytes J Clin Endocrinol Metab 2019 104 (12):5877-5892
Lihua Sun, Jing Ye, Yun Wang, Qiuju Chen, Yonglun Fu, Hui Tian, Qifeng Lyu, Xuefeng Lu* （通讯作者）, Yanping Kuang* Elevated basal luteinizing hormone does not impair the outcome of human menopausal gonadotropin and medroxyprogesterone acetate treatment cycles Scientific Report 2018 8:13835
Xuefeng Lu, Shuzin Khor, Qianqian Zhu, Lihua Sun, Yun Wang, Qiuju Chen, Ling Wu, Yonglun Fu, Hui Tian, Qifeng Lyu, Renfei Cai. Decrease in preovulatory serum estradiol is a valuable marker for predicting premature ovulation in natural/unstimulated in vitro fertilization cycle. J Ovarian Res 2017 11:96
Lu, Xuefeng,Hong, Qingqing,Sun, LiHua,Chen, Qiuju,Fu, Yonglun,Ai,Ai,Lyu, Qifeng,Kuang, Yanping Dual trigger for final oocyte maturation improves the oocyte retrieval rate of suboptimal responders to gonadotropin-releasing hormone agonist Fertility and Sterility 2016 106（6）：1356~1362
Xuefeng Lu, Qiuju Chen, Yonglun Fu, Ai Ai, Qifeng Lyu,Yanping Kuang. Elevated progesterone on the trigger day does not impair the outcome of Human Menotrophins Gonadotrophin and Medroxyprogesterone acetate treatment cycles. Scientific report 2016 6:31112.
Xuefeng Lu, Zhilan Liua, Xiaoxin Zhanga, Xiaomi、Wei Shenb, Aimin Zhao Prothrombotic state of patients with unexplained recurrent spontaneous abortion International Journal of Gynecology and Obstetrics 2015 131: 161-65
Wenkang Huang, Lv Geng, Rong Deng, Shaoyong Lu, Guangli Ma, Jianxiu Yu, Jian Zhang, Wei Liu, Tingjun Hou and Xuefeng Lu Prediction of Human Clearance Based on Animal Data and Molecular Properties Chem Biol Drug Des 2015 86: 990-97
Linkai Mou, Molin Li, Shao-Yong Lu, Shuai Li, Qiancheng Shen, Jian Zhang, Chuangang Li and Xuefeng Lu Unraveling the role of Arg4 and Arg6 in the auto-inhibition mechanism of GSK3β from molecular dynamics simulation Chem Biol Drug Des 2014 83:721-30
Shijin Xiao, Xuefeng Lu （共同第一作者）,Li Zhang, Shimin Bao, and Aimin Zhao Study on the pathogenesis of autoimmune-type recurrent spontaneous abortion by establishing a new mouse model Eur J Obstet Gynecol Reprod Biol 2014 178:84-8
Mingfei Ji, Xubo Su, Xiaohong Su, Yingyi Chen, Wenkang Huang, Jian Zhang, Zhaobin Gao, Chuangang Li and Xuefeng Lu Identification of Novel Compounds for Human Bitter Taste Receptors Chem Biol Drug Des 2014 84:63-74
Xuefeng Lu, Mazur SJ, Tongxiang Lin, Appella E, Yang Xu. The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis Oncogene 2014 33:2655-54
Xuefeng Lu, Mazur SJ, Tongxiang Lin, Appella E, Yang Xu. The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis Oncogene 2014 33:2655-54
Xuefeng Lu, Dongping Liu, Yang Xu The gain of function of p53 cancer mutant in promoting mammary tumorigenesis Oncogene 2012 299:1-7
Yaxue Zhao, Xuefeng Lu, Chaoyie Yang, Zhimin Huang, Wei Fu, Tingjun Hou, Jian Zhang Computational modeling toward understanding agonist binding on dopamine J Chem Inf Model. 2010 50:1633-43.
Du D, Xu F, Yu L, Zhang C, Lu X, Yuan H, Huang Q, Zhang F, Bao H, Jia L, Wu X, Zhu X, Zhang X, Zhang Z, Chen Z. The tight junction protein, occludin, regulates the directional migration of epithelial cells Dev Cell. 2010 18:52-63
Guang Yang, Qingrun Li, Siyuan Ren, Xuefeng Lu, Longhou Fang,Wenchao Zho,Fan Zhang,Feilai Xu,Zhe Zhang, Rong Zeng, Friedrich Lottspeich and Zhengjun Chen. Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins Proteomics 2009 9:4944–4961
Guang Yang, Qingrun Li, Siyuan Ren, Xuefeng Lu, Longhou Fang,Wenchao Zho,Fan Zhang,Feilai Xu,Zhe Zhang, Rong Zeng, Friedrich Lottspeich and Zhengjun Chen. Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins Proteomics 2009 9:4944–4961
Xiujing Feng, Xuefeng Lu （共同第一作者）, Wenchao zhou, Xiaobo Man, Lake Qunfeng, Pjotr Knyazev, Zhe Zhang, Axel Ullrich, Zhengjun Chen Overexpression of Csk binding protein (Cbp) contributes to renal cell carcinogenesis Oncogene 2009 185:1-12
Guang Yang, Qingrun Li, Siyuan Ren, Xuefeng Lu, Longhou Fang,Wenchao Zho,Fan Zhang,Feilai Xu,Zhe Zhang, Rong Zeng, Friedrich Lottspeich and Zhengjun Chen. Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins Proteomics 2009 9:4944–4961
Xuefeng Lu （共同第一作者）, Xiujing Feng, Xiaobo Man, Guang Yang, Liang Tang, Dan Du, Haixin Yuan, Zhe Zhang, Yinkun Liu, Dennis Strand and Zhengjun Chen Aberrant Splicing of Hugl-1, the Human Homologue of Drosophila Tumor Suppressor Gene lgl, is Associated with Hepatocellular Carcinoma Progression Clinical cancer research 2009 15:3287-96