导师姓名： 黄荷凤 专业代码： 100211
性别： 女 专业名称： 妇产科学
培养单位： 附属国际和平妇幼保健院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市徐汇区衡山路910号国际和平妇幼保健院
邮编： 200030 邮箱地址： huanghefg@hotmail.com

研究方向 (点击浏览详细信息)
配子/胚胎源性疾病，生殖医学及助孕安全

社会任职
中国优生优育协会 副会长
国际科学顾问委员会委员（Members of the International Scientific Advisory Board）
中国科学院大学存济医学院 副院长
中国妇幼保健协会 副会长
上海市胚胎源性疾病重点实验室 主任
中国医师协会生殖医学专业委员会第一届委员会 副主任委员
中国医师协会医学遗传医师分会第一届临床生殖遗传专业委员会 副主任委员
英国皇家妇产科学院荣誉院士
中国医学科学院学部委员
中华医学会生殖医学会 副主任委员
中国中西医结合学会妇产科学会 副主任委员
中国科学院院士
中国中西医结合学会生殖医学专业委员会 主任委员
世界中联围产医学专业委员会第一届理事会 副会长
香港大学荣誉教授
遗传发育与精神神经疾病教育部重点实验室 副主任
生殖遗传教育部重点实验室 主任
澳大利亚阿德莱德大学客座教授
中国妇幼保健协会“生育保健专业专家委员会” 主任委员
发展中国家科学院院士

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2017YFC** “生殖健康及重大出生缺陷防控研究”重点专项：人类胚胎发育中的细胞编程与配子/胚胎源性疾病的发生机制 国家重点研发计划 2017-07~2020-12 1482万元 课题负责人
中加合作健康生命轨迹计划：预防儿童肥胖的社区-家庭-母婴综合干预队列研究 国家自然科学基金委中加合作 2017-01~2021-12 1500万元 课题负责人
** 雄激素对TET介导的卵母细胞去甲基化影响及传代效应机制研究 国家自然科学基金项目 2015-01~2018-12 80万元 主要责任人
** AR基因pre-mRNA剪接变体导致排卵障碍的转录调控机制研究 国家自然科学基金项目 2015-01~2018-12 40万元 主要责任人
** 胚胎着床过程中母-胎互作关键调控通路的生理和病理作用机制 国家自然科学基金 重大项目 2015-01~2018-12 240万元 课题负责人
14DJ** 智障、耳聋、脑瘫等常见先天异常的发病机制及产前筛查、分子诊断技术研发 上海市科委重点项目 2014-01~2016-12 350万元 子课题负责人
2013CB967404 性分化异常疾病与生殖干细胞转换相关性和机制研究 国家重大科学研究计划 2013-01~2017-12 0万元 课题参与人
精原细胞向生殖干细胞和生殖细胞转化的机制研究 国家重大科学研究计划 2013-01~2017-12 0万元 子课题负责人
2012CB944900 辅助生殖诱发胚胎源性疾病的风险评估和机制研究 国家重大科学研究计划 2012-01~2016-12 2598万元 主要责任人
2012BAI32B00 生殖健康状况评估及关键技术研究 国家科技支撑计划 2012-01~2016-12 4400万元 主要责任人
** 高糖对人胚胎干细胞向胰岛细胞分化过程中Igf2/H19差异甲基化区的调控及效应机制研究 国家自然科学基金项目 2011-01~2013-12 60万元 课题负责人
** 妊娠期宫内高糖环境对子代亲源性基因印记的影响及其遗传效应机制的研究 国家自然科学基金 2010-01~2012-12 30万元 课题负责人
2007AA02Z456 积极性优生途径——植入前胚胎基因诊断技术的临床应用和推广 国家高技术研究发展计划（863计划） 2007-06~2010-11 550万元 课题负责人
** Ca2+激活K2+通道在 人子宫内膜细胞的表达，功能及其在胚胎着床中的作用 国家自然科学基金 面上项目 2007-01~2009-12 28万元 课题负责人
卵细胞源性生长因子对人类卵泡发育调节机制的研究 国家自然科学基金 中加健康研究合作 2007-01~2007-01 45万元 课题负责人
**A1022 我国人类（疾病）胚胎干细胞库的建立与应用 国家高技术研究发展计划（863计划） 2006-12~2009-12 0万元 子课题负责人
2006CB504004 人类生育调节及其相关重要疾病的基础研究——受精和早期胚胎发育的表观遗传学 国家重点基础研究发展计划（973计划） 2006-12~2009-12 0万元 课题参与人
2006CB944006 生殖细胞健康与母胎识别及豁免的分子基础－同种、种间人身母胎识别的网络调控机制 国家重大科学研究计划 2006-06~2011-12 0万元 子课题负责人
** 亲代基因印迹校正的雌核发育/雄核发育技术创建人自体胚胎干细胞的研究 国家自然科学基金 2005-01~2007-12 21万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Akbar R, Ullah K, Rahman T U, Cheng Y, Pang H Y, Jin L Y, Wang Q J, Huang H F* （通讯作者）, Sheng J Z*. miR-183-5p regulates uterine receptivity and enhances embryo implantation. Journal of molecular endocrinology 2020 64(1): 43–52.
Gao L, Wu D, Wu Y, Yang Z, Sheng J, Lin X*, Huang H* （通讯作者） MiR-3940-5p promotes granulosa cell proliferation through targeting KCNA5 in polycystic ovarian syndrome. Biochemical and biophysical research communications 2020 524(4): 791–797
Gu W, Lin J, Hou Y Y, Lin N, Song M F, Zeng W J, Shang J, Huang H F* （通讯作者） Effects of low-dose aspirin on the prevention of preeclampsia and pregnancy outcomes: A randomized controlled trial from Shanghai, China European journal of obstetrics, gynecology, and reproductive biology 2020 248: 156–163.
Zhou C L, Xu G F, Yang Q, Wang H H, Guo M X, Xiong Y M, Guo X Y, Hou M, Jin L Y, Sheng J Z, He L, Jin L*, Huang H F* （通讯作者） Diminished verbal ability among children conceived through ART with exposure to high serum estradiol in utero Journal of assisted reproduction and genetics 2020 /
Xue R H, Lin X H, Wu D D, Huang H F*. （通讯作者） Monitoring maternal triglyceride concentrations during pregnancy could be useful in reducing perinatal mortality. Acta obstetricia et gynecologica Scandinavica, 2020 /
Wu Y T, Li C, Zhang C J, Huang H F*. （通讯作者） Is termination of early pregnancy indicated in women with COVID-19? European journal of obstetrics, gynecology, and reproductive biology 2020 /
Li C, Su Y F, Jin L, Guo Y Y, Ding G L, Tang L, Cai M, Huang H F* （通讯作者）, Liu X M* Association between higher levels of serum estradiol and elevated levels of fibrin (fibrinogen) degradation products in late pregnancy following assisted reproductive technology treatment. Thrombosis research 2020 187: 63–71.
Wen L, Liu Q, Xu J, Liu X, Shi C, Yang Z, Zhang Y, Xu H, Liu J*, Yang H*, Huang H* （通讯作者）, Qiao J*, Tang F*, Chen Z J* Recent advances in mammalian reproductive biology Science China. Life sciences 2020 63(1): 18–58
Wu D D, Gao L, Huang O, Ullah K, Guo M X, Liu Y, Zhang J, Chen L, Fan J X, Sheng J Z, Lin X H*, Huang H F*. （通讯作者） Increased Adverse Pregnancy Outcomes Associated With Stage 1 Hypertension in a Low-Risk Cohort: Evidence From 47 874 Cases. Hypertension 2020 75(3): 772–780.
Zhang Y, Zhang C, Shu J, Guo J, Chang H M, Leung P C K*, Sheng J Z, Huang H*. （通讯作者） Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis. Human reproduction update 2020 26(2): 247–263
Wu Y, Zhang C, Liu H, Duan C, Li C, Fan J, Li H, Chen L, Xu H, Li X, Guo Y, Wang Y, Li X, Li J, Zhang T, You Y, Li H, Yang S, Tao X, Xu Y, Lao H, Wen M, Zhou Y, Wang J, Chen Y, Meng D, Zhai J, Ye Y, Zhong Q, Yang X, Zhang D, Zhang J, Wu X, Chen W, Dennis CL, Huang H*. （通讯作者） Perinatal depressive and anxiety symptoms of pregnant women along with COVID-19 outbreak in China American journal of obstetrics and gynecology 2020 223(2):240.e1–9.
Yu C J, Liu X, Zhou Z Y, Chen X J, Meng Y C, Gu H C, Xu J J, Ding G L, Liu X M, Sheng J Z*, Huang H F* （通讯作者） The casein kinase 2α promotes the occurrence polycystic ovary syndrome. Biochemical and biophysical research communication 2020 /
Wu Y, Liu C, Dong L, Zhang C, Chen Y, Liu J, Zhang C, Duan C, Zhang H, Mol BW, Dennis CL, Yin T*, Yang J*, Huang H* （通讯作者） Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding BJOG 2020 127(9):1109–15
Yang X, Yu Y, Zhang C, Zhang Y, Chen Z, Dubois L, Huang H* （通讯作者）, Fraser W*, Fan J* The association between isolated maternal hypothyroxinemia in early pregnancy and preterm birth. Thyroid?: official journal of the American Thyroid Association 2020 /
Zhao H, Li Y, He L, Pu W, Yu W, Li Y, Wu Y T, Xu C, Wei Y, Ding Q, Song B L, Huang H* （通讯作者）, Zhou B*. In Vivo AAV-CRISPR/Cas9-Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia. Circulation 2020 141(1): 67–79
Lin J, Liu H, Wu D D, Hu H T, Wang H H, Zhou C L, Liu X M, Chen X J, Sheng J Z, Huang H F*. （通讯作者） Long interpregnancy interval and adverse perinatal outcomes: A retrospective cohort study. Science China. Life sciences 2020 63(6): 898–904.
Xue R H, Li J, Huang Z, Li Z Z, Chen L, Lin Q, Huang H F* （通讯作者） Is tubal endometriosis an asymmetric disease? A 17-year retrospective study Archives of gynecology and obstetrics, Germany 2020 301(3): 721–727
Wang Yin-Yu, Liu Ye, Li Cheng, Lin Jing, Liu Xin-Mei, Sheng Jian-Zhong, Huang He-Feng*. （通讯作者） Frequency and risk factors for recurrent gestational diabetes mellitus in primiparous women: a case control study BMC ENDOCRINE DISORDERS 2019 19
Zheng D, Zeng L, Yang R, Lian Y, Zhu Y M, Liang X, Tang L, Wang H, Cao Y, Hao G, Liu J, Zhao J, Wang R, Mol B W, Li R, Huang H F* （通讯作者）, Qiao J* Intracytoplasmic sperm injection (ICSI) versus conventional in vitro fertilisation (IVF) in couples with non-severe male infertility (NSMI-ICSI): protocol for a multicentre randomised controlled trial BMJ open 2019 9(9): e030366
Duan C C, Li C, He Y C, Xu J J, Shi C Y, Hu H T, Su Y F, Chen L, Tan Y J, Liu Z W, Sheng J Z, Fraser W D, Wu Y T*, Huang H F*. Oocyte exposure to supraphysiological estradiol during ovarian stimulation increased the risk of adverse perinatal outcomes after frozen-thawed embryo transfer: a retrospective cohort study. Journal of developmental origins of health and disease 2019 1-11
Zhang Yong, Zhang Chen, Yang Xi, Yang Shuai, Meng Yu, Liu Zhiwei, Peeters Robin P., Huang He-Feng* （通讯作者）, Korevaar Tim I. M.*, Fan Jianxia*. Association of Maternal Thyroid Function and Thyroidal Response to Human Chorionic Gonadotropin with Early Fetal Growth THYROID 2019 29（4）：586-594
Zou Kexin, Ding Guolian, Huang Hefeng*. （通讯作者） Advances in research into gamete and embryo-fetal origins of adult diseases SCIENCE CHINA-LIFE SCIENCES 2019 62（3）：360-368
Hou Min, Gu Hang-Chao, Wang Hui-Hui, Liu Xin-Mei, Zhou Cheng-Liang, Yang Qian, Jiang Zi-Ru, Lin Jing, Wu Yi-Mei, Wu Yan-Ting, Sheng Jian-Zhong, Huang He-Feng* （通讯作者） Prenatal exposure to testosterone induces cardiac hypertrophy in adult female rats through enhanced Pkc delta expression in cardiac myocytes JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 2019 128
Zhan Chen, Yang Xi, Zhang Yong, Guo Fei, Yang Shuai, Peeters Robin P, Korevaar Tim I M, Fan Jianxia*, Huang He-Feng* （通讯作者） Association Between Maternal Thyroid Hormones and Birth Weight at Early and Late Pregnancy. The Journal of clinical endocrinology and metabolism 2019 0
Zhang X Y, Xiong Y M, Tan Y J, Wang L, Li R, Zhang Y, Liu X M, Lin X H, Jin L, Hu Y T, Tang Z H, Wu Z M, Yin F H, Wang Z Q, Xiao Y, Sheng J Z, Huang H F* （通讯作者） Melatonin rescues impaired penetration ability of human spermatozoa induced by mitochondrial dysfunction Reproduction (Cambridge, England) 2019 158(5): 465–475.
Fan Jianxia, Zhang Yong, Zhang Chen, Barjaktarovic Mirjana, Yang Xi, Peeters Robin, Huang Hefeng （通讯作者）, Korevaar Tim Persistency of Thyroid Dysfunction From Early To Late Pregnancy. Thyroid : official journal of the American Thyroid Association 2019 0
Zhu Hong, Chen Bin, Cheng Yi, Zhou Yin, Yan Yi-Shang, Luo Qiong, Jiang Ying, Sheng Jian-Zhong, Ding Guo-Lian, Huang He-Feng （通讯作者） Insulin Therapy for Gestational Diabetes Mellitus Does Not Fully Protect Offspring From Diet-Induced Metabolic Disorders DIABETES 2019 68（4）：696-708
Chen Xi, Lin Hui, Yang Daping, Xu Wei, Liu Guangwei, Liu Xinmei, Sheng Jianzhong, Huang Hefeng （通讯作者） Early-life undernutrition reprograms CD4(+) T-cell glycolysis and epigenetics to facilitate asthma JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2019 143（6）：2038
Guo Mengxi, Zhou Chengliang, Xu Gufeng, Tang Lin, Ruan Yechun, Yu Ying, Lin Xianhua, Wu Dandan, Chen Hao, Yu Priscilla, Jin Luyang, Wang Yinyu, Wu Yimei, Ullah Kamran, Rahman Tanzil Ur, Liu Xinmei, Sheng Jianzhong, Chan Hsiao-Chang, Huang Hefeng （通讯作者） An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction. Science China. Life sciences 2019 0
Li Jing-Yi, Liu Yi-Feng, Xu Hai-Yan, Zhang Jun-Yu, Lv Ping-Ping, Liu Miao-E, Ying Yan-Yun, Qian Ye-Qing, Li Kun, Li Cheng, Huang Yun, Xu Gu-Feng, Ding Guo-Lian, Mao Yu-Chan, Xu Chen-Ming, Liu Xin-Mei, Sheng Jian-Zhong, Zhang Dan, Huang He-Feng （通讯作者） Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. Journal of molecular cell biology 2019 0
Li Xiang-Juan, Pan Hai-Tao, Chen Juan-Juan, Fu Yi-Bin, Fang Min, He Guo-Hua, Zhang Tao, Ding Hai-Gang, Yu Bin, Cheng Yi, Tan Ya-Jing, Zhao Fa-Lin, Morse Abraham N., Huang He-Feng （通讯作者） Proteomics of Uterosacral Ligament Connective Tissue from Women with and without Pelvic Organ Prolapse PROTEOMICS CLINICAL APPLICATIONS 2019 13（4）
Li Cheng, Wu Yan-Ting, Zhu Qian, Zhang Hui-Yu, Huang Zhen, Zhang Duo, Qi Hang, Liang Gui-Ling, He Xiao-Qing, Wang Xiao-Feng, Tang Xue, Huang He-Feng* （通讯作者）, Zhang Jian*. TRPV4 is involved in levonorgestrel-induced reduction in oviduct ciliary beating JOURNAL OF PATHOLOGY 2019 248（1）：77-87
Guo X-Y, Shu J., Fu X-H, Chen X-P, Zhang L., Ji M-X, Liu X-M, Yu T-T, Sheng J-Z, Huang H-F*. （通讯作者） Improving the effectiveness of lifestyle interventions for gestational diabetes prevention: a meta-analysis and meta-regression BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY 2019 16（3）：311-320
Yu Tiantian, Feng Chun, Lv Pingping, Xu Gufeng, Hong Lihua, Xiong Yimeng, Guo Xiaoyan, Li Tong, Sheng Jianzhong, Huang Hefeng （通讯作者）, Liu Xinmei Decreased decidual epithelial sodium channel (ENaC) alpha and gamma subunits in recurrent pregnancy loss (RPL) SCIENCE CHINA-LIFE SCIENCES 2019 62（7）：988-990
Liu Ye, Wang Yinyu, Wang Fangfang, Pan Jiexue, Xu Jingjing, Li Jingyi, Zhou Chengliang, Ding Guolian, Wu Yanting, Liu Xinmei, Sheng Jianzhong, Huang Hefeng*. （通讯作者） Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants SCIENCE CHINA-LIFE SCIENCES 2019 62（2）：257-267
Lin Xian-Hua, Wu Dan-Dan, Li Cheng, Xu Yi-Jing, Gao Ling, Lass Geffen, Zhang Jian, Tian Shen, Ivanova Deyana, Tang Lin, Chen Lei, Ding Rong, Liu Xi-Mei, Han Mi, Fan Jian-Xia, Li Xiao-Feng, Sheng Jian-Zhong, O'Byrne Kevin T, Huang He-Feng （通讯作者） Maternal High Triglyceride Levels During Early Pregnancy and Risk of Preterm Delivery: A Retrospective Cohort Study. The Journal of clinical endocrinology and metabolism 2019 104（4）：1249-1258
Yu Dan-Qing, Lv Ping-Ping, Yan Yi-Shang, Xu Guan-Xin, Sadhukhan Annapurna, Dong Shan, Shen Yan, Ren Jun, Zhang Xue-Ying, Feng Chun, Huang Yi-Ting, Tian Shen, Zhou Yin, Cai Yi-Ting, Ming Zhen-Hua, Ding Guo-Lian, Zhu Hong, Sheng Jian-Zhong, Jin Min*, Huang He-Feng*. （通讯作者） Intrauterine exposure to hyperglycemia retards the development of brown adipose tissue FASEB JOURNAL 2019 33（4）：5425-5439
Liu H, Li H, Li C, Chen L, Zhang C, Liu Z, Wu Y*, Huang H* （通讯作者） Associations between Maternal Sleep Quality Throughout Pregnancy and Newborn Birth Weight Behavioral sleep medicine 2019 1–13
Jiang Ziru, Jin Li, Shi Weihui, Xi Ji, Hu Yulian, Liu Xinmei, Sheng Jianzhong, Ding Guolian*, Huang Hefeng*. （通讯作者） A combination of follicle stimulating hormone, estradiol and age is associated with the pregnancy outcome for women undergoing assisted reproduction: a retrospective cohort analysis SCIENCE CHINA-LIFE SCIENCES 2019 62（1）：112-118
Zhang Qianqian, Chen Hao, Wang Yi, Zhang Chen, Tang Zhen, Li Hong, Huang Xiaoyi, Ouyang Fengxiu, Huang Hefeng （通讯作者）, Liu Zhiwei Severe vitamin D deficiency in the first trimester is associated with placental inflammation in high-risk singleton pregnancy CLINICAL NUTRITION 2019 38（4）：1921-1926
Zhou Yin, Zhu Hong, Wu Hai-Yan, Jin Lu-Yang, Chen Bin, Pang Hai-Yan, Ming Zhen-Hua, Cheng Yi, Zhou Cheng-Liang, Guo Meng-Xi, Huang Yi-Ting, Yu Dan-Qing, Sheng Jian-Zhong, Huang He-Feng*. （通讯作者） Diet-Induced Paternal Obesity Impairs Cognitive Function in Offspring by Mediating Epigenetic Modifications in Spermatozoa OBESITY 2018 26（11）：1749-1757
Hong L, Yu T, Xu H, Hou N, Cheng Q, Lai L, Wang Q, Sheng J, Huang H* （通讯作者） Down-regulation of miR-378a-3p induces decidual cell apoptosis: a possible mechanism for early pregnancy loss. HUMAN REPRODUCTION 2018 33卷1期11-22页
Zhou C, Yu Y, Yang Q, Wang H, Hou M, Jin L, Zhang F, Sheng J, Miao M, Yang X, Huang HF*. （通讯作者） Motor development delay in offspring is associated with prenatal telbivudine exposure. MEDICINE 2018 97卷9期
Chen Songchang, Li Shuyuan, Zhang Junyu, Zhang Lanlan, Chen Yiyao, Wang Li, Jin Li, Hu Yuting, Qi Xiaoping*, Huang Hefeng* （通讯作者）, Xu Chenming*. Preimplantation Genetic Diagnosis of Multiple Endocrine Neoplasia Type 2A Using Informative Markers Identified by Targeted Sequencing THYROID 2018 28（3）：281-287
Wu YT, Li C, Zhu YM, Zou SH, Wu QF, Wang LP, Wu Y, Yin R, Shi CY, Lin J, Jiang ZR, Xu YJ, Su YF, Zhang J, Sheng JZ, Fraser WD, Liu ZW, Huang HF*. （通讯作者） Outcomes of neonates born following transfers of frozen-thawed cleavage-stage embryos with blastomere loss: a prospective, multicenter, cohort study. BMC MEDICINE 2018 16卷
Ren J, Cheng Y, Ming ZH, Dong XY, Zhou YZ, Ding GL, Pang HY, Rahman TU, Akbar R, Huang HF* （通讯作者）, Sheng JZ* Intrauterine hyperglycemia exposure results in intergenerational inheritance via DNA methylation reprogramming on F1 PGCs. EPIGENETICS & CHROMATIN 2018 11卷
Li C, Zhang HY, Liang Y, Xia W, Zhu Q, Zhang D, Huang Z, Liang GL, Xue RH, Qi H, He XQ, Yuan JJ, Tan YJ, Huang HF* （通讯作者）, Zhang J*. Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 2018 16卷1-8 文献号: 59
Hu HT, Xu JJ, Lin J, Li C, Wu YT, Sheng JZ, Liu XM*, Huang HF* （通讯作者） Association between first caesarean delivery and adverse outcomes in subsequent pregnancy: a retrospective cohort study BMC PREGNANCY AND CHILDBIRTH 2018 18卷
Li Kun, Li Rui, Ni Ya, Sun Peibei, Liu Ye, Zhang Dan, Huang Hefeng （通讯作者） Novel distance-progesterone-combined selection approach improves human sperm quality JOURNAL OF TRANSLATIONAL MEDICINE 2018 16
Jin Li, Yang Qian, Zhou Chengliang, Liu Lanxin, Wang Huihui, Hou Min, Wu Yimei, Shi Fengtao, Sheng Jianzhong, Huang Hefeng （通讯作者） Profiles for long non-coding RNAs in ovarian granulosa cells from women with PCOS with or without hyperandrogenism REPRODUCTIVE BIOMEDICINE ONLINE 2018 37（5）613-623
Wang HH, Zhou CL, Lv M, Yang Q, Li JX, Hou M, Lin J, Liu XM, Wu YT, Sheng JZ, Huang HF* （通讯作者） Prenatal high estradiol exposure induces sex-specific and dietarily reversible insulin resistance through decreased hypothalamic INSR. ENDOCRINOLOGY 2018 159卷1期465-476页
Zhang Dan, Liu Yifeng, Zhang Zhou, Lv Pingping, Liu Yun, Li Jingyi, Wu Yiqing, Zhang Runjv, Huang Yun, Xu Gufeng, Qian Yeqing, Qian Yuli, Chen Songchang, Xu Chenming, Shen Jun, Zhu Linling, Chen Kai, Zhu Bo, Ye Xiaoqun, Mao Yuchan, Bo Xingsheng, Zhou Caiyun, Wang Tingting, Chen Dianfu, Yang Weijun, Tan Yajing, Song Yang, Zhou Daizhan, Sheng Jianzhong, Gao Huijuan, Zhu Yimin, Li Meigen, Wu Liping, He Lin, Huang Hefeng （通讯作者） Basonuclin 1 deficiency is a cause of primary ovarian insufficiency HUMAN MOLECULAR GENETICS 2018 27（21）3787-3800
Pan JX, Tan YJ, Wang FF, Hou NN, Xiang YQ, Zhang JY, Liu Y, Qu F, Meng Q, Xu J, Sheng JZ, Huang HF*. （通讯作者） Aberrant expression and DNA methylation of lipid metabolism genes in PCOS: a new insight into its pathogenesis. CLINICAL EPIGENETICS 2018 10卷
Chen XJ, Chen F, Lv PP, Zhang D, Ding GL, Hu XL, Feng C, Sheng JZ, Huang HF* （通讯作者） Maternal high estradiol exposure alters CDKN1C and IGF2 expression in human placenta. PLACENTA 2018 61卷72-79页
Lin XH, Wang H, Wu DD, Ullah K, Yu TT, Ur Rahman T, Huang HF* （通讯作者） High Leptin Level Attenuates Embryo Development in Overweight/Obese Infertile Women by Inhibiting Proliferation and Promotes Apoptosis in Granule Cell. HORMONE AND METABOLIC RESEARCH 2017 49卷7期534-541页
Zhang Y, Dai X, Yang S, Zhang C, Han M, Huang HF* （通讯作者）, Fan J* Maternal low thyroxin levels are associated with adverse pregnancy outcomes in a Chinese population. PLOS ONE 2017 12卷5期?
Tian S, Lin XH, Xiong YM, Liu ME, Yu TT, Lv M, Zhao W, Xu GF, Ding GL, Xu CM, Jin M, Feng C, Wu YT, Tan YJ, Gao Q, Zhang J, Li C, Ren J, Jin LY, Chen B, Zhu H, Zhang XY, Chen SC, Liu XM, Liu Y, Zhang JY, Wang L, Zhang P, Chen XJ, Jin L, Chen X, Meng YC, Wu DD, Lin H, Yang Q, Zhou CL, Li XZ, Wang YY, Xiang YQ, Liu ZW, Gao L, Chen LT, Pan HJ, Li R, Zhang FH, Xing LF, Zhu YM, Klausen C, Leung PC, Li JX, Sun F, Sheng JZ, Huang HF* （通讯作者） Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism EBioMedicine 2017 S2352-3964(17)30015-4
Sun YX, Zhang YX, Zhang D, Xu CM, Chen SC, Zhang JY, Ruan YC, Chen F, Zhang RJ, Qian YQ, Liu YF, Jin LY, Yu TT, Xu HY, Luo YQ, Liu XM, Sun F, Sheng JZ, Huang HF* （通讯作者） XCI-escaping gene KDM5C contributes to ovarian development via downregulating miR-320a. HUMAN GENETICS 2017 136卷2期227-239?页
Rahman TU, Ullah K, Ke ZH, Guo MX, Jin LY, Ren J, Zhou YZ, Cheng Y, Dong XY, Pang HY, Wang TT, Sheng JZ*, Huang HF*. （通讯作者） Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling. ONCOTARGET 2017 8卷32期53450-53464页
Zhang H, Wang G, Liu L, Liang X, Lin Y, Lin YY, Chou CF, Liu MF, Huang H* （通讯作者）, Sun F*. KH-type splicing regulatory protein is a new component of chromatoid body. REPRODUCTION 2017 154卷6期723-733页
Ullah K, Ur Rahman T, Wu DD, Lin XH, Liu Y, Guo XY, Leung PCK, Zhang RJ, Huang HF* （通讯作者）, Sheng JZ*. Phoenixin-14 concentrations are increased in association with luteinizing hormone and nesfatin-1 concentrations in women with polycystic ovary syndrome. CLINICA CHIMICA ACTA 2017 471卷243-247页
Xu GF, Zhou CL, Xiong YM, Li JY, Yu TT, Tian S, Lin XH, Liao Y, Lv Y, Zhang FH, Liu ZW, Shi YY, Shen Y, Sha J, Zhang D, Zhu YM, Sheng JZ, Huang HF* （通讯作者） Reduced Intellectual Ability in Offspring of Ovarian Hyperstimulation Syndrome: A Cohort Study. EBIOMEDICINE 2017 20卷263-267页
Lingjuan He, Yan Li, Yi Li, Wenjuan Pu, Xiuzhen Huang, Xueying Tian, Yue Wang, Hui Zhang, Qiaozhen Liu, Libo Zhang, Huan Zhao, Juan Tang, Hongbin Ji, Dongqing Cai, Zhibo Han, Zhongchao Han, Yu Nie, Shengshou Hu, Qing-Dong Wang, Ruilin Sun, Jian Fei, Fengchao Wang, Ting Chen, Yan Yan, Hefeng Huang* （通讯作者）, William T Pu & Bin Zhou* Enhancing the precision of genetic lineage tracing using dual recombinases. NATURE MEDICINE 2017 23卷12期1488-1498页
Zhang Y, Zhang Y, Ding GL, Liu XM, Ye J, Sheng JZ, Fan J*, Huang HF* （通讯作者） Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia. Oncotarget 2017 14837
Ullah K, Rahman TU, Pan HT, Guo MX, Dong XY, Liu J, Jin LY, Cheng Y, Ke ZH, Ren J, Lin XH, Qiu XX, Wang TT, Huang HF* （通讯作者）, Sheng JZ.* Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium. JOURNAL OF MOLECULAR ENDOCRINOLOGY 2017 59卷2期105-119页
Chen LT, Qu F, Zhang FH, Wu YT, Xing LF, Huang HF*. （通讯作者） Maternal anxiety associated with in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) outcomes and risk of difficult toddler temperament: A three-year case-control study. JOURNAL OF OBSTETRICS AND GYNAECOLOGY 2017 37卷7期965-969页
Sun F, Qian W, Zhang C, Fan JX*, Huang HF*. Correlation of Maternal Serum Homocysteine in the First Trimester with the Development of Gestational Hypertension and Preeclampsia. MEDICAL SCIENCE MONITOR 2017 23卷5396-5401页
Jiang ZR , Wang YY , Lin J , Xu JJ , Ding GL , Huang HF* （通讯作者） Genetic and epigenetic risks of assisted reproduction. BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY 2017 44卷90-104页
Zhang JY, Chen SC, Chen YY, Li SY, Zhang LL, Shen YH, Chang CX, Xiang YQ, Huang HF* （通讯作者）, Xu CM*. Targeted sequencing identifies a novel SH2D1A pathogenic variant in a Chinese family: Carrier screening and prenatal genetic testing. PLOS ONE 2017 12卷2期
Zhao MD, Cheng JL, Yan JJ, Chen FY, Sheng JZ, Sun DL, Chen J, Miao J, Zhang RJ, Zheng CH*, Huang HF* （通讯作者） Hyaluronic acid reagent functional chitosan-PeI conjugate with aQP2-sirNa suppressed endometriotic lesion formatio INTERNATIONAL JOURNAL OF NANOMEDICINE 2016 11卷1323-1336页
Gao Ling, Cao Jia-Tian, Liang Yan, Zhao Yi-Chao, Lin Xian-Hua, Li Xiao-Cui, Tan Ya-Jing, Li Jing-Yi, Zhou Cheng-Liang, Xu Hai-Yan, Sheng Jian-Zhong, Huang He-Feng*. （通讯作者） Calcitriol attenuates cardiac remodeling and dysfunction in a murine model of polycystic ovary syndrome Endocrine 2016 0.1007/s12020-015-0797-1
Gao Ling, Zhao Yi-Chao, Liang Yan, Lin Xian-Hua, Tan Ya-Jing, Wu Dan-Dan, Li Xin-Zhu, Ye Bo-Zhi, Kong Fan-Qi, Sheng Jian-Zhong, Huang He-Feng*. （通讯作者） The impaired myocardial ischemic tolerance in adult offspring of diabetic pregnancy is restored by maternal melatonin treatment Journal of Pineal Research 2016 10.1111/jpi.12351
Ke ZH, Pan JX, Jin LY, Xu HY, Yu TT, Ullah K, Rahman TU, Ren J, Cheng Y, Dong XY, Sheng JZ*, Huang HF*. （通讯作者） Bisphenol A Exposure May Induce Hepatic Lipid Accumulation via Reprogramming the DNA Methylation Patterns of Genes Involved in Lipid Metabolism SCIENTIFIC REPORTS 2016 6卷文献号31331
Pan H, Zhang P, Li JR, Wang H, Jin MF, Feng C, Huang HF* （通讯作者） c-Fos-Regulated Matrix Metalloproteinase-9 Expression is Involved in 17β-Estradiol-Promoted Invasion of Human Endometrial Stromal Cell CURRENT MOLECULAR MEDICINE 2016 16卷3期266-275页
Jin M, Lv PP, Yu TT, Shen JM, Feng C, Huang HF* （通讯作者） IGFBP1 Involved in the Decreased Birth Weight Due to Fetal High Estrogen Exposure in Mice. BIOLOGY OF REPRODUCTION 2016 95（5）文献号96
Song Y, Wang ES, Xing LL, Shi S, Qu F, Zhang D, Li JY, Shu J, Meng Y, Sheng JZ, Zhou JH, Huang HF* （通讯作者） Follicle-Stimulating Hormone Induces Postmenopausal Dyslipidemia Through Inhibiting Hepatic Cholesterol Metabolism JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2016 101(1):253-262页
Wu Y, Pan H, Wang WM, Xu D, Zhang L, Gu ZQ, Bai Q, Qi J, Huang HF* （通讯作者） A possible relationship between serum sex hormones and benign prostatic hyperplasia/lower urinary tract symptoms in men who underwent transurethral prostate resection ASIAN JOURNAL OF ANDROLOGY 2016 2016
Shu Jing, Xing Li-Li, Ding Guo-Lian, Liu Xin-Mei, Yan Qing-Feng, Huang He-Feng*. （通讯作者） Effects of ovarian hyperstimulation on mitochondria in oocytes and early embryos REPRODUCTION FERTILITY AND DEVELOPMENT 2016 28:1214-1222
Liu AX, Zhang D, Zhu YM, Gao HJ, Jiang JY, Hu XL, Lv PP, Leung PC, Huang HF* （通讯作者） Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line. CURRENT MOLECULAR MEDICINE 2016 16（3）：299-311页
Fan JX, Yang S, Qian W, Shi FT, Huang HF* （通讯作者） Comparison of the Reference Intervals Used for the Evaluation of Maternal Thyroid Function During Pregnancy Using Sequential and Nonsequential Methods. CHINESE MEDICAL JOURNAL 2016 129(7):785-791页
Liu XM, Chan HC, Ding GL, Cai J, Song Y, Wang TT, Zhang D, Chen H, Yu MK, Wu YT, Qu F, Liu Y, Lu YC, Adashi EY, Sheng JZ*, Huang HF* （通讯作者） FSH regulates fat accumulation and redistribution in aging through the Gαi/Ca(2+)/CREB pathway AGING CELL 2015 14(3):409-420
Zhang J, Li C, Zhao WH, Xi X, Cao SJ, Ping H, Qin GJ, Cheng L, Huang HF* （通讯作者） Association between levonorgestrel emergency contraception and the risk of ectopic pregnancy: a multicenter case-control study Scientific reports 2015 5:8487
Tan YJ, Zhang XY, Ding GL, Li R, Wang L, Jin L, Lin XH, Gao L, Sheng JZ, Huang HF* （通讯作者） Aquaporin7 plays a crucial role in tolerance to hyperosmotic stress and in the survival of oocytes during cryopreservation SCIENTIFIC REPORTS 2015 5:17741
Wang F, Pan J, Liu Y, Meng Q, Lv P, Qu F, Ding GL, Klausen C, Leung PC, Chan HC, Yao W, Zhou CY, Shi B, Zhang J, Sheng J, Huang H （通讯作者） Alternative splicing of the androgen receptor in polycystic ovary syndrome Proceedings of the National Academy of Sciences of the United States of America 2015 10.1073/pnas.
Meng Y, Lv PP, Ding GL, Yu TT, Liu Y, Shen Y, Hu XL, Lin XH, Tian S, Lv M, Song Y, Guo MX, Ke ZH, Xu H, Sheng JZ, Shi FT*, Huang HF* （通讯作者） High Maternal Serum Estradiol Levels Induce Dyslipidemia in Human Newborns via a Hepatic HMGCR Estrogen Response Element Scientific reports 2015 5
Huang YT, Zhou J, Shi S, Xu HY, Qu F, Zhang D, Chen YD, Yang J, Huang HF* （通讯作者）, Sheng JZ* Identification of Estrogen Response Element in Aquaporin-3 Gene that Mediates Estrogen-induced Cell Migration and Invasion in Estrogen Receptor-positive Breast Cancer. SCIENTIFIC REPORTS 2015 5:12484
Zhang D, Li J, Xu G, Zhang R, Zhou C, Qian Y, Liu Y, Chen L, Zhu B, Ye X, Qu F, Liu X, Shi S, Yang W, Sheng J, Huang H* （通讯作者） Follicle-stimulating hormone promotes age-related endometrial atrophy through cross-talk with transforming growth factor beta signal transduction pathway. AGING CELL 2015 14(2):284-287
Ding GL, Liu Y, Liu ME, Pan JX, Guo MX, Sheng JZ, Huang HF* （通讯作者） The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis/ ASIAN JOURNAL OF ANDROLOGY ASIAN JOURNAL OF ANDROLOGY 2015 17:948-953
Lin XH, Liu ME, Xu HY, Chen XJ, Wang H, Tian S, Sheng JZ, Huang HF* （通讯作者） Leptin down-regulates γ-ENaC expression: a novel mechanism involved in low endometrial receptivity FERTILITY AND STERILITY/ 2015 103:228
Hu XL, Feng C, Lin XH, Zhong ZX, Zhu YM, Lv PP, Lv M, Meng Y, Zhang D, Lu XE, Jin F, Sheng JZ, Xu J#, Huang HF# （通讯作者） High maternal serum estradiol environment in the first trimester is associated with the increased risk of small-for-gestational-age birth. Physiology (Bethesda) 2014
Qu F, Zhang D, Chen LT, Wang FF, Pan JX, Zhu YM, Ma CM, Huang YT, Ye XQ, Sun SJ, Zheng WJ, Zhang RJ, Xu J, Xing LF#, Huang HF# （通讯作者） Auricular Acupressure Reduces Anxiety Levels and Improves Outcomes of in Vitro Fertilization: A Prospective, Randomized and Controlled Study Scientific Reports 2014 4(5028)
Liu XM, Zhang D, Wang TT, Sheng JZ, Huang HF# （通讯作者） Ion/Water channels for embryo implantation barrier. Physiology (Bethesda) 2014 29(3):186-95
Xu GF, Zhang JY, Pan HT, Tian S, Liu ME, Yu TT, Li JY, Ying WW, Yao WM, Lin XH, Lv Y, Su WW, Ye XQ, Zhang FH, Pan JX, Liu Y, Zhou CL, Zhang D, Liu XM, Zhu YM, Sheng JZ#, Huang HF# （通讯作者） Cardiovascular dysfunction in offspring of ovarian hyperstimulated women and effects of estradiol and progesterone: a retrospective cohort study and proteomics analysis. J Clin Endocrinol Metab. 2014
Ding GL, Huang HF# （通讯作者） Role for tet in hyperglycemia-induced demethylation: a novel mechanism of diabetic metabolic memory Diabetes 2014 63(9):2906-8
Lu YC, Yang J, Ding GL, Shi S, Zhang D, Jin L, Pan JX, Lin XH, Zhu YM, Sheng JZ#, Huang HF# （通讯作者） Small conductance calcium-activated potassium channel 3 (SK3) is a modulator of endometrial remodeling during endometrial growth J Clin Endocrinol Metab 2014
Ruan YC, Guo JH, Liu X, Zhang R, Tsang LL, Dong JD, Chen H, Yu MK, Jiang X, Zhang XH, Fok KL, Chung YW, Huang H# （通讯作者）, Zhou WL#, Chan HC# Activation of the epithelial Na(+) channel triggers prostaglandin E(2) release and production required for embryo implantation Nature Medicine 2012 18(7):1112-7.
Yong Chao Lu, Hui Chen, Kin Lam Fok, Lai Ling Tsang, Mei Kuen Yu, Xiao Hu Zhang, Jing Chen, Xiaohua Jiang, Yiu Wa Chung, Alvin Chun Hang Ma5, Anskar Yu Hung Leung, He Feng Huang# （通讯作者）, Hsiao Chang Chan# CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell Research 2012 22(3):1453–1466
Zhang D, Tan YJ, Qu F, Sheng JZ, Huang HF# （通讯作者） Functions of water channels in male and female reproductive systems. Mol Aspects Med 2012 33(5-6): 676-90
Yin LJ, Zhang Y, Lv PP, He WH, Wu YT, Liu AX, Ding GL, Dong MY, Qu F, Xu CM, Zhu XM, Huang HF# （通讯作者） Insufficient maintenance DNA methylation is associated with abnormal embryonic development. BMC Med 2012 13:(10)26
Ding GL, Wang FF, Shu J, Tian S, Jiang Y, Zhang D, Wang N, Luo Q, Zhang Y, Jin F, Peter CK Leung, Sheng JZ#, Huang HF# （通讯作者） Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia Diabetes 2012 61:1133-1142