导师姓名： 吴琰婷 专业代码： 100211
性别： 女 专业名称： 妇产科学
培养单位： 附属国际和平妇幼保健院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师： 兼
联系方式： 上海市徐汇区衡山路922号建汇大厦3507科教科Email: yanting_wu@163.com
邮编： 200030 邮箱地址： yanting_wu@163.com

研究方向 (点击浏览详细信息)
胚胎/胎儿源性疾病
生殖内分泌
辅助生殖技术安全性

社会任职
上海市青年联合会 委员
中国妇幼保健协会生育保健专业委员会 秘书长

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
SQ2018YFC100102 早孕期自然流产病因学及临床防治研究 国家重点研发计划 2019-01~2022-12 60万元 子课题负责人
冻融胚胎卵裂球丢失子代随访及研究 上海市卫生和计划生育委员会 2019-01~2021-12 10万元 课题负责人
YYXX 上海市“医苑新星”****医学人才 上海市卫生健康委员会 2019-01~2021-12 20万元 课题负责人
SHDC12018X17 冻融胚胎卵裂球丢失子代随访及研究 上海申康医院发展中心，临床研究培育项目 2018-11~2021-11 30万元 课题负责人
1 Life tree FIT study 上海交通大学医学院国际及港澳台地区科研合作项目 2018-10~2019-09 15万元 课题负责人
** 颗粒细胞PPARG基因剪接变体在PCOS发病机制中的作用 国家自然科学基金面上项目 2017-01~2020-12 57万元 课题负责人
2016YFC** 中国人群辅助生殖人口及子代队列建立与应用基础研究 国家重点研发计划 2016-07~2021-06 110万元 子课题负责人
YG2015MS42 人类早期胚胎冻融过程中卵裂球丢失对胚胎移植结局及子代健康的影响及其机制研究 上海交通大学 “医工交叉研究基金”面上项目 2016-01~2018-12 21万元 课题负责人
2012BAI32B04 避孕节育措施对生殖健康的影响及助孕新技术和新方法研究 十二五科技支撑计划“生殖健康状况评估及关键技术研究”子课题 2012-01~2016-12 50万元 课题参与人
2011R50013-02 GDF-9 R146C突变与卵巢衰老相关机制研究 浙江省重点科技创新团队项目 2012-01~2015-12 5万元 课题负责人
** 卵源性生长因子GDF-9和BMP-15基因突变与卵巢衰老相关机制研究 国家自然科学基金青年项目 2010-01~2012-12 20万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Hou M, Gu HC, Wang HH, Liu XM, Zhou CL, Yang Q, Jiang ZR, Lin J, Wu YM, Wu YT, Sheng JZ, Huang HF. Prenatal exposure to testosterone induces cardiac hypertrophy in adult female rats through enhanced Pkcδ expression in cardiac myocytes. Mol Cell Cardiol. Journal of Molecular and Cellular Cardiology. 2019 11;128:1-10.
Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H. Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants. Sci China Life Sci 2019 62(2):257-267.
Li C#, Wu YT# （共同第一作者）, Zhu Q, Zhang HY, Huang Z, Zhang D, Qi H, Liang GL, He XQ, Wang XF, Tang X, Huang HF*, Zhang J*. TRPV4 is involved in levonorgestrel-induced reduction in oviduct ciliary beating. The Journal of Pathology 2019 248(1):77-87.
Wu YT# （共同第一作者）, Li C#, Zhu YM, Zou SH, Wu QF, Wang LP, Wu Y, Ying R, Shi CY, Lin J, Jiang ZR, Xu YJ, Su YF, Zhang J, Sheng JZ, Fraser WD, Liu ZW, Huang HF Outcomes of neonates born following transfers of frozen-thawed cleavage-stage embryos with blastomere loss: a prospective, multicenter, cohort study BMC Medicine 2018 Jun 19;16(1):96
Tian S, Lin XH, Xiong YM, Liu ME, Yu TT, Lv M, Zhao W, Xu GF, Ding GL, Xu CM, Jin M, Feng C, Wu YT, Tan YJ, Gao Q, Zhang J, Li C, Ren J, Jin LY, Chen B, Zhu H, Zhang XY, Chen SC, Liu XM, Liu Y, Zhang JY, Wang L, Zhang P, Chen XJ, Jin L, Chen X, Meng YC, Wu DD, Lin H, Yang Q, Zhou CL, Li XZ, Wang YY, Xiang YQ, Liu ZW, Gao L, Chen LT, Pan HJ, Li R, Zhang FH, Xing LF, Zhu YM, Klausen C, Leung PC, Li JX, Sun F, Sheng JZ, Huang HF Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism EBioMedicine 2017 Feb;16:275-283
Wu YT, Chang HM, Huang HF, Sheng JZ, Leung PC Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells Mol Hum Reprod. 2017 Mar;23(3):155-165
Y Wu, C Li, H Huang. Outcomes of neonates born following transfer of frozen-thawed cleavage embryos with blastomere loss: a multicenter prospective study in China Fertil Steril 2017 Sep;108( 3 S): e167.
Lin XH, Wu DD, Gao L, Zhang JY, Pan HT, Wang H, Li C, Zhang P, Guo MX, Wu YT, Tan YJ, Jin L, Xiang YQ, Li JX, Sheng JZ, Huang HF Altered DNA methylation in neonates born large-for-gestational-age is associated with cardiometabolic risk in children Oncotarget 2016 Dec 27;7(52):86511-86521
Wu YT, Wu Y, Chen SC, Zhou F, Yang CB, Xie ZW, Xu CM, Jin HM A Novel Molecular Cytogenetic Finding of Leiomyomatosis Peritonealis Disseminata Gynecol Obstet Invest 2016 81:186-192
Wu YT, Wu Y, Zhang JY, Hou NN, Liu AX, Pan JX, Lu JY, Sheng JZ, Huang HF Preliminary proteomic analysis on the alterations in follicular fluid proteins from women undergoing natural cycles or controlled ovarian hyperstimulation J Assist Reprod Genet 2015 Mar;32(3):417-27
Liu XM, Chan HC, Ding GL, Cai J, Song Y, Wang TT, Zhang D, Chen H, Yu MK, Wu YT, Qu F, Liu Y, Lu YC, Adashi EY, Sheng JZ, Huang HF FSH regulates fat accumulation and redistribution in aging through the Gαi/Ca(2+) /CREB pathway Aging Cell 2015 Aging Cell
Wu Y, Chen LT, Qu F, Sheikh I.S, Wu YT* （通讯作者） Chinese Herbal Medicine for Premature Ovarian Failure: A Systematic Review and Meta-Analysis European Journal of Integrative Medicine 2014 6(3), 382–391
Xu J, Ye J, Wu Y, Zhang H, Luo Q, Han C, Ye X, Wang H, He J, Huang H, Liu Y, Dong M* Reduced fetal telomere length in gestational diabetes PLoS One 2014 22;9(1):e86161
Liu Y, Cao L, Li Z, Zhou D, Liu W, Shen Q, Wu Y, Zhang D, Hu X, Wang T, Ye J, Weng X, Zhang H, Zhang D, Zhang Z, Liu F, He L, Shi Y* A Genome-Wide Association Study Identifies a Locus on TERT for Mean Telomere Length in Han Chinese PLoS One 2014 21; 9(1):e85043
Wang TT, Ke ZH, Song Y, Chen LT, Chen XJ, Feng C, Zhang D, Zhang RJ, Wu YT, Zhang Y, Sheng JZ, Huang HF* Identification of a mutation in GDF9 as a novel cause of diminished ovarian reserve in young women. Hum Reprod 2013 28(9):2473-8
Yin LJ, Zhang Y, Lv PP, He WH, Wu YT, Liu AX, Ding GL, Dong MY, Qu F, Xu CM, Zhu XM, Huang HF* Insufficient maintenance DNA methylation is associated with abnormal embryonic development BMC Med 2012 Mar 13;10:26
Wu YT （共同第一作者）, Wang TT, Chen XJ, Zhu XM, Dong MY, Sheng JZ, Xu CM, Huang HF* Bone morphogenetic protein-15 in follicle fluid combined with age may differentiate between successful and unsuccessful poor ovarian responders. Reprod Biol Endocrinol 2012 Dec 26;10:116
Wang TT, Wu YT, Dong MY, Sheng JZ, Leung PC, Huang HF* G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve Fertil Steril 2010 94(6):2490-2
Tang L, Wang TT, Wu YT, Zhou CY, Huang HF* High expression levels of cyclin B1 and Polo-like kinase 1 in ectopic endometrial cells associated with abnormal cell cycle regulation of endometriosis Fertil Steril 2009 91(4):979-87
Qu F, Zhou J, Burrows E, Luo Q, Wu Y, Wang T, Huang H* Acupuncture may improve the absorption of baicalin from the extracts of Scutellaria baicalensis Georgi in rats with pelvic inflammation Forsch Komplementmed 2008 15(5):282-285
Zhang Y, Zhang YL, Feng C, Wu YT, Liu AX, Sheng JZ, Cai J, Huang HF* Comparative proteomic analysis of human placenta derived from assisted reproductive technology Proteomics 2008 8(20):4344-4356
Li ZX, Wang TT, Wu YT, Xu CM, Dong MY, Sheng JZ, Huang HF* Adriamycin induces H2AX phosphorylation in human spermatozoa Asian J Androl 2008 10(5): 749-757
Wu YT# （共同第一作者）, Tang L#, Cai J, Lu XE, Xu J, Zhu XM, Luo Q, Huang HF* High bone morphogenetic protein-15 level in follicular fluid is associated with high quality oocyte and subsequent embryonic development Hum Reprod 2007 22(6): 1526- 1531
Liu AX, Zhu YM, Luo Q, Wu YT, Gao HJ, Zhu XM, Xu CM, Huang HF* Specific peptide patterns of follicular fluids at different growth stages analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Biochim Biophys Acta 2007 1770(1):29-38
吴琰婷 陆秀娥 王婷婷 何荣环 徐键 黄荷凤 超排卵周期卵巢低反应患者卵泡液骨形成蛋白-15水平升高 浙江大学学报：医学版 2007 2007，36（5）：439-442.
Luo Q, Ning W, Wu Y, Zhu X, Jin F, Sheng J, Huang H* Altered expression of interleukin-18 in the ectopic and eutopic endometrium of women with endometriosis J Reprod Immunol 2006 72(1-2):108-117