导师姓名： 刘锦纷 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属儿童医学中心 三级学科/
专业领域： 胸心外
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： 邮箱地址： liujinfen2002@126.com

研究方向 (点击浏览详细信息)
婴幼儿复杂先心病的外科治疗
虚拟心脏手术及3D打印技术在其中的应用
先天性心脏病的致病基因筛查及分子网络研究

社会任职
美国世界儿科与先天性心脏病协会会员、美国心血管外科协会会员、中华小儿外科学会心胸外科学组组长

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2013CB945304 人类心肌细胞分化增殖潜能及分子特征研究 国家重大科学研究计划 2013-01~2017-07 520万元 课题负责人
03.01.045 上海市重中之重临床医学中心-小儿心血管 上海市卫计委 2012-01~2016-12 650万元 课题负责人
** 先天性心脏病肺循环计算机模拟血流动力学研究 国家自然基金 2011-01~2013-12 33万元 课题负责人
先天性心脏病早期综合治疗研究 卫生部公益性行业科研专项 2010-07~2013-06 272万元 主要责任人
10DZ** 先天性心脏病的产前筛查和早期综合诊疗研究 市科委生药处重大项目 2010-07~2013-06 350万元 主要责任人
09JC** 先天性心脏病肺循环计算机模拟血流动力学研究 上海市科委基础重点项目 2009-09~2011-08 35万元 课题负责人
符合生理的肺循环计算机模拟血流动力学研究 上海交通大学重大项目培育基金 2009-01~2010-12 5万元 课题负责人
08ZZ59 复杂先天性心脏病肺循环计算机模拟血流动力学的实验研究 上海市教委,发展基金 2008-01~2010-12 15万元 课题负责人
** 计算机模拟血流动力学应用于复杂先心手术的实验研究 国家自然基金委,面上项目 2007-01~2009-12 29万元
围生期先天性心脏病诊断和治疗的基础和临床研究 上海市科委,国际合作 2005-10~2007-09 25万元
** 经胎儿镜宫内转基因保持胎羊动脉导管开放研究 国家自然基金委,面上项目 2005-01~2007-12 21万元

学术论文 作者论文标题期刊名出版年卷期页码
Ye L, Qiu L, Zhang H, Chen H, Jiang C, Hong H, Liu J. （通讯作者） Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation. Sci Rep. 2016 6:23188
J.L. Liu, W.M. Zhang, Q. Yan, H.F. Hong, J.F. Liu （通讯作者） Effects of Band Position on Hemodynamics of Pulmonary Artery: A Numerical Study of Patient-specific Virtual Procedure 2015 World Congress on Medical Physics and Biomedical Engineering 2015 12:44-58
杜舟,朱丽敏,刘金龙,刘锦纷 （通讯作者） 先天性气管狭窄气道形态评估和早期预后的相关性 中华胸心血管外科杂志 2015 31（8）:494-498
Lincai Ye, Meng Yin, Yu Xia, Chuan Jiang, Haifa Hong, Jinfen Liu （通讯作者） Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects PLoS One 2015 10(10):e**
Haifa Hong, Lincai Ye, Huiwen Chen, Yu Xia, Yue Liu, Jinfen Liu, Yanan Lu, Haibo Zhang. Isobaric Tags for Relative and Absolute Quantitation-Based Proteomic Analysis of Patent and Constricted Ductus Arteriosus Tissues Confirms the Systemic Regulation of Ductus Arteriosus Closure J Cardiovasc Pharmacol 2015 66(2):204-13
Jinlong Liu, Qi Sun, Yi Qian, Haifa Hong, Qian Wang, Yanjun Sun, Mitsu Umezu, Jinfen Liu （通讯作者） Medical Image-based Hemodynamic Analysis for Modified Blalock-Taussig Shunt Journal of Mechanics in Medicine and Biology 2015 15(3): **
Liu X, Hong H, Zhang H, Xu Z, Liu J （通讯作者）, Qiu L Treatment Strategies for Primary Tumors of the Heart in Children: A 10-Year Experience. Ann Thorac Surg 2015 100(5):1744-9
Youjin Li, Yanrui Jiang, Shenghui Li, Xiaoming Shen, Jinfen Liu （通讯作者）, Fan Jiang Pre- and Postnatal Risk Factors in Relationto Allergic Rhinitis in School-Aged Children in China PLOS ONE 2015 10(2): e**
L Ye, L Qiu, H Zhang, H Chen, C Jiang, H Hong, J Liu （通讯作者） Proliferation of cardiomyocytes in young infants, future implication in human heart regeneration IFMBE Proceedings 2015 51:276-283
Qi Sun, Jinlong Liu, Haibo Zhang, Jinghao Zheng, Haifa Hong, Yanjun Sun, Huiwen Chen,Jinfen Liu, Qian Wang, Yingzheng Liu Influence of exercise on three types of Fontan modifications: comparison by numerical simulations Journal of Mechanics in Medicine and Biology 2014 14(1) :**
Qi Sun, Jinlong Liu, Yi Qian, Haibo Zhang, Qian Wang, Yanjun Sun, Haifa Hong, Jinfen Liu （通讯作者） Computational Hemodynamic Analysis of Patient-specific Virtual Operations for Total Cavopulmonary Connection with Dual Superior Venae Cavae European Journal of Cardio-thoracic Surgery 2014 45(3):564-569
Sun Y, Ye L, Liu J, Hong H Hypoxia-induced cytosolic calcium influx is mediated primarily by the reverse mode of Na+/Ca2+ exchanger in smooth muscle cells of fetal small pulmonary arteries. J Obstet Gynaecol Res 2014 40(6):1578-1583
Yu Xia, Haifa Hong, Lincai Ye, Yanlin Wang, Huiwen Chen, Jinfen Liu （通讯作者） Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients Journal of Proteomics 2013 84:78-91
Hong H, Menon PG, Zhang H, Ye L, Zhu Z, Chen H, Liu J （通讯作者） Postsurgical Comparison of Pulsatile Hemodynamics in Five Unique Total Cavopulmonary Connections: Identifying Ideal Connection Strategies Ann Thorac Surg 2013 96:1398-404
Jinlong Liu, Yi Qian, Qi Sun, Jinfen Liu （通讯作者）, Mitsuo Umezu Use of Computational Fluid Dynamics to Estimate Hemodynamic Effects of Respiration on Hypoplastic Left Heart Syndrome Surgery: Total Cavopulmonary Connection Treatments The Scientific World Journal 2013 131597
Ruidong Zhang （通讯作者）, Yue Huang, Mazhong Zhang,Jie Bai,Jinfen Liu Serum Antibodies to the Heparin/Platelet Factor 4 Complex Are an Independent Predictor of Thrombotic Complications Following Pediatric Fontan Surgery Clinical and Applied Thrombosis/Hemostasis 2012
Ning Ma,Zhenyu Wang,Hao Chen,Yanjun Sun,Haifa Hong,Qi Sun,Meng Yin,Jinfen Liu （通讯作者） Development of the novel biotube inserting technique for acceleration of thick-walled autologous tissue-engineered vascular grafts fabrication J Mater Sci Mater Med 2011
Jinfen Liu,Lisheng Qiu,Zhongqun Cone reconstruction of the tricuspid valve in Ebstein anomaly with or without one and a half ventricle repair The Journal of Thoracic and Cardiovascular Surgery 2011
Huiwen Chen,Jinfen Liu （通讯作者）,Wei Gao,Haifa Hong Late complete atrioventricular block and tuicuspid regurgitation after percutaneous closure of a perimembranous ventricular septal defect J Thorac Cardiovasc Surg 2010
Sun Qi, Liu Jinfen （通讯作者） 17.Influence of antegrade pulmonary blood flow on the hemodynamic performance bidirectional ncavopulmonary anastomosis: A numerical study Medical Engineering Physics 2009
Hong Haifa, Liu Jinfen （通讯作者） 18.Hypoxia-induced Cytosolic Calcium Decrease is Mediated primarily by the Forward Mode of Na+/Ca2+ Exchanger in Smooth Muscle Cells of Fetal Ductus Arteriosus .Pediatric Cardiology 2009
Sun Qi, Liu Jinfen （通讯作者） Patient-specific computational fluid dynamic simulation of a bilateral bidirectional Glenn connection Medical Bilogical Engineering Computing 2008