薛向东 长聘教轨副教授

邮箱：xuexd@sjtu.edu.cn
主页：https://scholar.google.com/citations?user=ksr8ZNsAAAAJ&hl=en


个人简历 研究方向 发表论文
薛向东
长聘教轨副教授/课题组组长
邮箱：xuexd@sjtu.edu.cn
课题组主页：https://www.x-mol.com/groups/xiangdong_xue
Google Scholar: https://scholar.google.com/citations?user=ksr8ZNsAAAAJ&hl=en
地址：上海市东川路800号上海交通大学药学院6号楼
薛向东，上海交通大学药学院，长聘教轨副教授，课题组组长，博士生导师。博士毕业于中国科学院大学，国家纳米科学中心，师从梁兴杰研究员。2015年至2020年，分别在美国华盛顿大学和加州大学戴维斯分校从事博士后研究工作。2020年12月全职加入上海交通大学药学院。目前已发表高水平SCI论文46篇，总影响因子超过400，论文被引超过2000次，H因子24。其中包括以第一或通讯作者在 Nature Nanotechnology, Nature Communications, Advanced Materials, ACS Nano, Biomaterials, Advanced Functional Materials, Advanced Science, Journal of Controlled Release, Nano Research等国际权威刊物上发表的论文17篇（总影响因子>180）。发表论文被F-1000，福布斯，科学日报，美国化学学会等知名媒体报道。申请 PCT 国际专利 2项，中国专利 5 项。同时，长期担任Biomaterials, Advanced Sciences, Small, ACS Applied Material & Interface, Chemical Engineering Journal, Acta Biomaterialia, Journal of Controlled Release, Molecular Pharmaceutics等近20个国际学术期刊的审稿人。
课题组招收博士和硕士研究生，热忱欢迎有化学、材料和生物医学研究背景的青年才俊加入！诚聘博士后青年****！


o智能小分子药物自组装递送系统的构建及其对相关疾病的治疗和成像
o基于可调谐造影剂的磁共振成像及相关成像技术对早期癌症的精确诊断
o免疫调控和免疫治疗对晚期转移型癌症的治疗

1. Wang, Z.?; Xue, X.?; Lu, H.; He, Y.; Lu, Z.; Chen, Z.; Yuan, Y.; Tang, N.; Dreyer, C. A.; Quigley, L.; Curro, N.; Lam, K. S.; Walton, J. H.; Lin, T.-y.; Louie, A. Y.; Gilbert, D. A.; Liu, K.; Ferrara, K. W.; Li, Y., Two-way magnetic resonance tuning and enhanced subtraction imaging for non-invasive and quantitative biological imaging. Nature Nanotechnology 2020, 15, 482–490. IF=31.538. 被中外媒体报道99次，包括F1000，福布斯 (Forbes)，科学日报 (ScienceDaily)，新浪网，生物艺术，纳米人等知名媒体。F1000 (Rated Exceptional)。https://www.nature.com/articles/s41565-020-0678-5.pdf
2. Xue, X.?; Huang, Y.?; Bo, R.; Jia, B.; Wu, H.; Yuan, Y.; Wang, Z.; Ma, Z.; Jing, D.; Xu, X.; Yu, W.; Lin, T.-y.; Li, Y., Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment. Nature Communications 2018, 9 (1), 3653. IF= 12.121. 申请PCT国际专利一项。基于该工作的纳米药物已帮助美国实验室拿到600余万美元的基金资助，包括1个小型企业创新研究基金 (SBIR) 和2个美国国立卫生院的研究项目基金 (R01)。
https://doi.org/10.1038/s41467-018-06093-5
3. Xue, X.?; Zhao, Y.?; Dai, L.; Zhang, X.; Hao, X.; Zhang, C.; Huo, S.; Liu, J.; Liu, C.; Kumar, A.; Chen, W.-Q.; Zou, G.; Liang, X.-J., Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission. Advanced Materials 2014, 26 (5), 712-717. IF= 27.398. 首次用聚集诱导发光分子递送药物的工作之一，被聚集诱导发光概念的提出者唐本忠院士撰文，以“有价值的化学”高亮报道在美国化学学会网站上.
http://onlinelibrary.wiley.com/store/10.1002/adma./asset/adma.pdf?v=1&t=iz0ldjzy&s=0153d6c3da81f**a5138e5f0795f045a2c
4. Xue, X.; Bo, R.; Qu, H.; Jia, B.; Xiao, W.; Yuan, Y.; Vapniarsky, N.; Lindstrom, A.; Wu, H.; Zhang, D.; Li, L.; Ricci, M.; Ma, Z.; Zhu, Z.; Lin, T.-y.; Louie, A. Y.; Li, Y., A nephrotoxicity-free, iron-based contrast agent for magnetic resonance imaging of tumors. Biomaterials 2020, 257, 120234. IF=10.317. http://www.sciencedirect.com/science/article/pii/S0**4804
5. Xue, X.?; Huang, Y.?; Wang, X.; Wang, Z.; Carney, R. P.; Li, X.; Yuan, Y.; He, Y.; Lin, T.-y.; Li, Y., Self-indicating, fully active pharmaceutical ingredients nanoparticles (FAPIN) for multimodal imaging guided trimodality cancer therapy. Biomaterials 2018, 161, 203-215. IF=10.317.
http://www.sciencedirect.com/science/article/pii/S0**0632
6. Xue, X.?; Jin, S.?; Zhang, C.; Yang, K.; Huo, S.; Chen, F.; Zou, G.; Liang, X.-J., Probe-Inspired Nano-Prodrug with Dual-Color Fluorogenic Property Reveals Spatiotemporal Drug Release in Living Cells. ACS Nano 2015, 9(3), 2729-2739. IF= 14.588. http://pubs.acs.org/doi/pdfplus/10.1021/nn**
7. Wang, Z.?; Xue, X.?; He, Y.; Lu, Z.; Jia, B.; Wu, H.; Yuan, Y.; Huang, Y.; Wang, H.; Lu, H.; Lam, K. S.; Lin, T.-Y.; Li, Y., Novel Redox-Responsive Polymeric Magnetosomes with Tunable Magnetic Resonance Property for In Vivo Drug Release Visualization and Dual-Modal Cancer Therapy. Advanced Functional Materials 2018, **. IF=16.836.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.
8. Xue, X.?; Jin, S.?; Li, Z.; Zhang, C.; Guo, W.; Hu, L.; Wang, P. C.; Zhang, J.; Liang, X.-J., Through-Bond Energy Transfer Cassette with Dual-Stokes Shifts for “Double Checked” Cell Imaging. Advanced Science 2017, **. IF=15.840. https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.
9. Yuan, Y.; Bo, R.; Jing, D.; Ma, Z.; Wang, Z.; Lin, T.-y.; Dong, L.; Xue, X.*; Li, Y.*, Excipient-free porphyrin/SN-38 based nanotheranostics for drug delivery and cell imaging. Nano Research 2020, 13, 503-510. IF=8.183.
https://link.springer.com/content/pdf/10.1007/s12274-020-2641-z.pdf
10. Yu, W.?; Xue, X.?; Ma, A.-H.; Ruan, Y.; Zhang, H.; Cheng, F.; Li, Y.; Pan, C.-X.; Lin, T.-Y., Self-Assembled Nanoparticle-Mediated Chemophototherapy Reverses the Drug Resistance of Bladder Cancers through Dual AKT/ERK Inhibition. Advanced Therapeutics 2020, 3, **. IF=N/A.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adtp.
11. Xue, X.?; Ricci, M.?; Qu, H.; Lindstrom, A.; Zhang, D.; Wu, H.; Lin, T.-Y.; Li, Y., Iron-crosslinked Rososome with robust stability and high drug loading for synergistic cancer therapy. Journal of Controlled Release 2020. IF=7.727. http://www.sciencedirect.com/science/article/pii/S0**5848
12. Xue, X.; Lindstrom, A.; Qu, H.; Li, Y., Recent advances on small-molecule nanomedicines for cancer treatment. WIREs Nanomedicine and Nanobiotechnology 2019, 12 (3), e1607. IF=7.689.
https://onlinelibrary.wiley.com/doi/abs/10.1002/wnan.1607
13. Xue, X.; Lindstrom, A.; Li, Y., Porphyrin-Based Nanomedicines for Cancer Treatment. Bioconjugate Chemistry 2019, 30 (6), 1585-1603. IF=4.031.
https://doi.org/10.1021/acs.bioconjchem.9b00231
14. Yuan, Y.; He, Y.; Bo, R.; Ma, Z.; Wang, Z.; Dong, L.; Lin, T.-y.; Xue, X.*; Li, Y.*, A facile approach to fabricate self-assembled magnetic nanotheranostics for drug delivery and imaging. Nanoscale 2018, 10 (46), 21634-21639. IF=6.895.
https://pubs.rsc.org/en/content/articlepdf/2018/nr/c8nr05141k
15. Yang, X.?; Xue, X.?; Luo, Y.; Lin, T.-y.; Zhang, H.; Lac, D.; Xiao, K.; He, Y.; Jia, B.; Lam, K. S.; Li, Y., Sub-100nm, long tumor retention SN-38-loaded photonic micelles for tri-modal cancer therapy. Journal of Controlled Release 2017, 261, 297 - 306. IF=7.727.
http://www.sciencedirect.com/science/article/pii/S0**7228
16. Xue, X.; Xu, J.; Wang, P. C.; Liang, X.-J., Subcellular behaviour evaluation of nanopharmaceuticals with aggregation-induced emission molecules. Journal of Materials Chemistry C 2016, 4, 2719-2730. IF=7.059.
http://pubs.rsc.org/en/content/articlepdf/2016/tc/c5tc03651h
17. Xue, X. ?; Zhao, Y. ?; Zhang, X.; Zhang, C.; Kumar, A.; Zhang, X.; Zou, G.; Wang, P.; Zhang, J.; Liang, X.-J., Phenylboronic acid-functionalized magnetic nanoparticles for one-step saccharides enrichment and mass spectrometry analysis. Biophysics Report 2015, 1 (2), 61-70. IF=N/A.
http://dx.doi.org/10.1007/s41048-015-0002-3