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上海交通大学医学院研究生导师简介 何志刚

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 何志刚 专业代码: 071006
性别: 专业名称: 神经生物学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: zhigang.he@childrens.harvard.edu 重庆南路280号,200025,64154900
研究方向 (点击浏览详细信息)
神经生物学
社会任职
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
050626Assessing the Role of Nogo Receptor and its Ligands in Axon Regeneration2005-09~~2009-06万元课题负责人
NS051788Signaling Mechanisms of Axon Regeneration by CNS Myelin2005-04~~2010-03万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Smith PD, Sun F., Park K., Cai B., Wang C., Kuwako K., Martinez-Carrasco I., Connolly L., He Z.#. SOCS3 deletion promotes optic nerve regeneration in vivo. Neuron,2009;64, 617-623
2、Shen Y., Tenney A.P., Busch S.A., Horn K.P., Cuascut F.X., Liu K., He Z., Silver J. Flanagan J.G.. PTP{sigma} Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration. Science,2009;326, 592-596
3、Park K, Liu K, Hu Y, Smith P, Chen W., Cai B, Xu B, Connolly L., Kramvis I., Sahin M, He Z.#. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science,2008;322, 963-966
4、Chivatakarn O, Kaneko S, He Z, Tessier-Lavigne M, Giger RJ.. The Nogo-66 receptor NgR1 is requiredonly for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors. J Neurosci,2007;27(27):7117-7124.
5、Kaneko S, Iwanami A, Nakamura M, Kishino A, Kikuchi K, Shibata S, Okano HJ, Ikegami T, Moriya A, KonishiO, Nakayama C, Kumagai K, Kimura T, Sato Y, Goshima Y, Taniguchi M, Ito M, He Z, Toyama Y, Okano H.. A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injuredspinal cord. Nature Medicine,2007;12, 1380-1389.
6、Kaneko S., Wang J., Kaneko M, Yiu G., Hurrell J., Chitnis T., Khoury S.J., He Z.#. ProtectingAxonal Degeneration by Increasing NAD Levels in Experimental Autoimmune Encephalomyelitis Models. J Neurosci,2006;26(38):9794-9804.
7、Koprivica V, Cho KS, Park JB, Yiu G, Atwal J, Gore B, Kim JA, Lin E, Tessier-Lavigne M, Chen DF, He Z.#. EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science,2005;310(5745):106-110.
8、Wang J, Zhai Q, Chen Y, Lin E, Gu W, McBurney MW, He Z.#. A local mechanism mediates NAD- dependent protection of axon degeneration. J Cell Biol,2005;170(3):349-355
9、Park JB, Yiu G, Kaneko S, Wang J, Chang J, He Z.#. A TNF receptor family member, TROY, is a coreceptorwith Nogo receptor in mediating the inhibitory activity of myelin inhibitors. Neuron,2005;45, 345-351.
10、Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, He Z. #. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth.. Nature,2002;417, 941-944.


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