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上海交通大学医学院研究生导师简介 刘俊岭

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 刘俊岭 专业代码: 071009
性别: 专业名称: 细胞生物学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: liujunling@hotmail.com liujl@shsmu.edu.cn
研究方向 (点击浏览详细信息)
血栓止血,动脉粥样硬化,肿瘤转移
社会任职
中国科学技术协会 中国病理生理学会委员
中华医学会细胞生物专业青年委员
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
81170479整合素αIIb亚基介导信号在血小板活化和血栓形成中的作用国家自然科学基金面上项目2012-01~~2015-1260万元主要责任人
2012CB518001GPCR介导的血管炎症和损伤科技部973重大科学研究计划2012-01~~2016-12220万元子课题负责人
81030039血小板介导预转移微环境的形成及其在肺癌转移中的作用国家自然科学基金重点项目2011-01~~2014-12200万元课题负责人
D0303100003血小板在肺癌预转移微环境形成中的作用研究上海市教育委员会,上海市教育发展基金2011-01~~2013-1215万元主要责任人
KLTH-2009-01卫生部血栓止血重点实验室开放课题卫生部2009-10~~2012-093万元主要责任人
09PJ1406800整合素alpha亚基介导信号及其调控机制研究上海市科委2009-07~~2011-0730万元主要责任人
NECT-08-0351新世纪优秀人才支持计划教育部2009-07~~2011-0750万元主要责任人
0720000030上海高校特聘教授上海市教委2009-01~~2011-1250万元主要责任人
学术论文 (#为通讯作者,*为共同第一作者)

1、Haixia Niu, Zhenlu Xu , Ding Li , Lin Zhang , Kemin Wang , Donald B. Taylor ,Junling Liu #, T. Kent Gartner. Peptide LSARLAF induces integrin β3 dependent outside-in signaling in platelets. Thrombosis Research,2012;130(2):203-9
2、Niu H, Chen X, Gruppo RA, Li D, Wang Y, Zhang L, Wang K, Chai W, Sun Y, Ding Z, Gartner TK, Liu J.#. Integrin αIIb-Mediated PI3K/Akt Activation in Platelets.Integrin αIIb-Mediated PI3K/Akt Activation in Platelets.. PLoS One,2012;7(10):e47356
3、Li D, Wang Y, Zhang L, Luo X, Li J, Chen X, Niu H, Wang K, Sun Y, Wang X, Yan Y, Chai W, Gartner TK, Liu J.#. Roles of purinergic receptor P2Y, G protein-coupled 12 in the development of atherosclerosis in apolipoprotein E-deficient mice.. Arterioscler Thromb Vasc Biol,2012;32(8):e81-9
4、Delaney MK, Liu J*, Zheng Y, Berndt MC, Du X.. The Role of Rac1 in Glycoprotein Ib-IX-Mediated Signal Transduction and Integrin Activation.. Arterioscler Thromb Vasc Biol,2012;32(11):2761-8.
5、Delaney MK, Liu J*, Zheng Y, Berndt MC, Du X.. The Role of Rac1 in Glycoprotein Ib-IX-Mediated Signal Transduction and Integrin Activation.. Arterioscler Thromb Vasc Biol,2012;32(11):2761-8.
6、Zhenyu Li, Guoying Zhang, Junling Liu, Aleksandra Stojanovic, Changgeng Ruan, Clifford A Lowell, and Xiaoping Du. . An important role of the SRC family kinase LYN in stimulating platelet granule secretion.. Journal of Biological Chemistry.,2010;285(17):12559-70
7、Zhang S, Hu L, Du H, Guo Y, Zhang Y, Niu H, Jin J, Zhang J, Junling Liu, Zhang X, Kunapuli SP, Ding Z. . BF0801, a novel adenine derivative, inhibits platelet activation via phosphodiesterase inhibition and P2Y12 antagonism.. Thromb Haemost.,2010;104(4):845-57.
8、Xiang B, Zhang G, Junling Liu, Morris AJ, Smyth SS, Gartner TK, Li Z. . A G(i) -independent mechanism mediating Akt phosphorylation in platelets.. J Thromb Haemost.,2010;8(9):2032-41
9、Zhen Weng, Ding Li, Lin Zhang, Jian Chen, Changgeng Ruan, Guoqiang Chen, T. Kent Gartner, and Junling Liu*. #. PTEN regulates collagen-induced platelet activation.. Blood,2010;116(14):2579-81.
10、Jose A. Guerrero, Mark Kyei, Susan Russell, Junling Liu, T. Kent Gartner, Brian Storrie, and Jerry Ware. . Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation.. Blood,2009;114(27):5541-6
11、Flevaris P, Li Z, Zhang G, Zheng Y, Liu J, Du X.. Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway.. Blood,2009;113(4):893-901.
12、Liu J*, Joglekar M, Ware J, Fitzgerald ME, Lowell CA, Berndt MC, Gartner TK.. Evaluation of the physiological significance of botrocetin/ von Willebrand factor in vitro signaling.. J Thromb Haemost.,2008;6(11):1915-22.
13、Guerrero JA*, Shafirstein G, Russell S, Varughese KI, Kanaji T, Liu J, Gartner TK, B?umler W, Jarvis GE, Ware J.. In vivo relevance for platelet glycoprotein Ibalpha residue Tyr276 in thrombus formation. . J Thromb Haemost.,2008;6(4):684-91.
14、Liu J*, Jackson CW, Gartner TK. The Src requirement for washed platelet aggregation and dense granule secretion in response to stimulation by a low level gamma-thrombin . J Thromb Haemost.,2008;6(6):1035-7
15、Yin H*, Liu J, Li Z, Berndt MC, Lowell CA, Du X.. Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. . Blood,2008;112(4):1139-46.
16、Guerrero JA*, Shafirstein G, Russell S, Varughese KI, Kanaji T, Liu J, Gartner TK, B?umler W, Jarvis GE, Ware J.. Platelet glycoprotein Ib alpha supports experimental lung metastasis. . Proc Natl Acad Sci U S A.,2007;104(21):9024-8
17、Liu J*, Ware J, Jackson CW, Gartner TK.. FcRgamma-chain dependent alphallbbeta3 elicited outside-in signaling. . J Thromb Haemost.,2007;5(2):426-8.
18、Liu J*, Ware J, Jackson CW, Gartner TK.. FcRgamma-chain signals in the absence of glycoprotein VI.. J Thromb Haemost.,2007;5(1):201-3.
19、Liu J*, Fitzgerald ME, Berndt MC, Jackson CW, Gartner TK.. Bruton’s tyrosine kinase is essential for botrocetin/ vWf-induced signaling and GPIb-dependent thrombus formation in vivo. . Blood,2006;108(8):2596-603
20、Zhao M*, Liu J, Wang C, Wang L, Liu H, Peng S.. Botrocetin/vWf-induced signaling through GPIb-IX-V produces TxA2 in a Ca2+ and aggregation-independent manner without utilizing other receptors. . J Med Chem.,2005;48(13):4285-92
21、Zhao M*, Liu J, Wang C, Wang L, Liu H, Peng S.. Synthesis and Biological Activity of Nitronyl Nitroxide Containing Peptides. . J Med Chem.,2005;48(13):4285-92
22、Liu J*, Jackson CW, Gruppo RA, Jennings LK, Gartner TK.. The beta3 subunit of the integrin alphaIIbbeta3 regulates alphaIIb-mediated outside-in signaling.. Blood.,2005;105(11):4345-52
23、Liu J*, Pestina TI, Berndt MC, Steward SA, Jackson CW, Gartner TK.. The roles of ADP and TXA2 in botrocetin/vWf- induced aggregation of washed platelets. J Thromb Haemost.,2004;2(12):2213-22.
24、Cho MJ*, Liu J, Pestina TI, Steward SA, Thomas DW, Coffman TM, Wang D, Jackson CW, Gartner TK.. The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation. . Blood,2003;101(7):2646-51.


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