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2、Liu B, Zheng Y, Wang TD, Xu HZ, Xia L, Zhang J, Wu YL, Chen GQ, Wang LS. Proteomic Identification of Common SCF Ubiquitin Ligase FBXO6-Interacting Glycoproteins in Three kinds of Cells. J Proteome Res,2012;11:1773-1781
3、Li W, Fu J, Cheng F, Zheng M, Zhang J, Liu G, Tang Y. Unbinding pathways of GW4064 from human farnesoid X receptor as revealed by molecular dynamics simulations. J Chem Inf Model,2012;52:3043-3052
4、Uckun F, Ma H, Zhang J, Ozer Z, Dovat S, Mao C, Ishkhanian R, Goodman P, Qazi S. Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of IKAROS. Proc Natl Acad Sci USA,2012;109:18072-18077
5、Duan XF, Eric B, Li Z, Timothy C, Zhang J, Huang Z, Su X, Pan Y, Wu L, Chi Q, Thomas S, Zhang S, Ma M, Hiroaki M, Chen GQ, Zhuang H. Crucial role of copper in detection of metal-coordinating odorants. Proc Natl Acad Sci USA,2012;109:3492-3497
6、Huang J, Yan J, Zhang J*, Zhu SG, Wang YL, Shi T, Zhu CH, Chen C, Liu X, Cheng JK, Mustelin T, Feng GS, Chen GQ, Yu J. SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with plasma membrane. Nat Commun,2012;3:911-911
7、Qin F, Ye W, Chen Y, Chen X, Li Y, Zhang J#, Chen HF. Atomistic Mechanism of microRNA Translation Upregulation via Molecular Dynamics Simulations. PLOS ONE,2012;7:43788-43788
8、Zhang Z, Chen L, Gao L, Lin K, Zhu L, Lu Y, Shi X, Gao Y, Zhou J, Xu P, Zhang J#, Wu G. Structural basis for the recognition of Asef by Adenomatous Polyposis Coli. Cell Res,2012;22:372-386
9、Qin F, Ye W, Chen Y, Chen X, Li Y, Zhang J#, Chen HF. Specific recognition between intrinsically disordered LEF and DNA. Phys Chem Chem Phys,2012;14:538-545
10、Ye W, Chen Y, Wang W, Yu QF, Li Y, Zhang J#, Chen HF. Insight into the Stability of Cross-b Amyloid Fibril from VEALYL Short Peptide with Molecular Dynamics Simulation. PLOS ONE,2012;7:36382-36382
11、Liu X, Liu B, Huang Z, Shi T, Chen Y, Zhang J#. SPPS: a sequence-based method for predicting probability of protein-protein interaction partners. PLOS ONE,2012;7:30938-30938
12、Tang J, Huang Z, Chen Y, Zhang Z, Liu G, Zhang J#. A novel inhibitor of human La protein with anti-HBV activity discovered by structure-based virtual screening and in vitro evaluation. PLOS ONE,2012;7:36363-36363
13、Huang Z, Jiang H, Liu X, Chen Y, Wang Q, Huang W, Shi T, Zhang J#. HEMD: an integrated tool of human epigenetic enzymes and chemical modulators for therapeutics. PLOS ONE,2012;7:39917-39917
14、Wang Q, Zheng M, Huang Z, Liu X, Zhou H, Chen Y, Shi T, Zhang J#. Toward Understanding the Molecular Basis for Chemical Allosteric Modulator Design. J Mol Graph Model,2012;38:324-333
15、Lu S, Huang Z, Huang W, Liu X, Chen Y, Shi T, Zhang J#. How calcium inhibits the magnesium-dependent kinase GSK3β: A molecular simulation study. PROTEINS: Structure, Function, and Bioinformatics,2012;1:10-12
16、Chen Y, Wen D, Huang Z, Huang M, Luo Y, Liu B, Lu H, WuY, Peng Y, Zhang J#. 2-(4-chlorophenyl)-2-oxoethyl-4-benzamidobenzoate derivatives, a novel class of SENP1 Inhibitors: Virtual screening, synthesis and biological evaluation. Bioorg Med Chem Lett,2012;22:6867-6870
17、Lu S, Huang W, Li X, Huang Z, Liu X, Chen Y, Shi T, Zhang J#. Insights into the Role of Magnesium Triad in myo-Inositol Monophosphatase: Metal Mechanism, Substrate Binding and Lithium Therapy. J Chem Inf Model,2012;52:2398-2409
18、Tang J, Zhang ZH, Huang M, Heise T, Zhang J*, Liu GL. Phosphorylation of human La protein at Ser366 by casein kinase II contributes to hepatitis B virus replication and expression in vitro. J Viral Hepatitis,2012;10:10-11
19、Lv M, Shi T, Mao X, Li X, Chen Y, Zhu J, Ni S, Shen X, Jiang H, Li J, Zhang J#, Huang J. 1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: a novel Cyclophilin A allosteric activator.. Biochem Biophys Res Commun,2012;425:938-943
20、Pang X, Zhang L, Lai L, Chen J, Wu Y, Yi Z, Zhang J, Qu W, Aggarwal BB, Liu M. 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Carcinogenesis,2011;32:904-912
21、Zhou C, Mo J, Wang X, Zhang J#, Gan LS. Theoretical study on flueggenines A and B: A comparison of calculated spectroscopic properties with IR, UV and ECD experimental data. J Mol Struct,2011;989:131-135
22、Zhang Z, Li H, Chen L, Lu X, Zhang J, Xu P, Lin K, Wu G. Molecular basis for the recognition of adenomatous polyposis coli by the discs large 1 protein. PLOS ONE,2011;6:23507-23507
23、Cai X, Zhang J*, Chen M, Wu Y, Wang X, Chen J, Zhang J, Shen X, Qu D, Jiang H. The effect of the potential PhoQ histidine kinase inhibitors on Shigella flexneri virulence. PLOS ONE,2011;6:23100-23100
24、Zhou C, Wang X, Mo J, Zhang J#, Gan LS. Optical Resolution and Structure Determination of New Indolizidine Alkaloids from Elaeocarpus sphaericus. Helvetica Chimica Acta,2011;94:347-354
25、Qin F, Jiang Y, Chen Y, Wu M, Yan G, Ye W, Li Y, Zhang J#, Chen HF. Conformational Selection or Induced Fit for Brinker and DNA Recognition. Phys Chem Chem Phys,2011;13:1407-1412
26、Li Z, Zhang H, Li Y, Zhang J#, Chen HF. Conformational Selection or Induced Fit for Brinker and DNA Recognition. Chem Biol Drug Des,2011;77:63-74
27、Tian S, Li Y, Wang J, Zhang J#, Hou T. ADME Evaluation in Drug Discovery. 9. Prediction of Oral Bioavailability in Humans Based on Molecular Properties and Structural Fingerprints. Mol Pharm,2011;8:841-851
28、Zhang H, Qin F, Ye W, Li Z, Ma S, Xia Y, Jiang Y, Zhu J, Li Y, Zhang J#, Chen HF. Revealing the Drug-Resistant Mechanism for Diarylpyrimidine Analogue Inhibitors of HIV-1 Reverse Transcriptase. Chem Biol Drug Des,2011;78:427-437
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30、Shi T, Lu Y, Liu X, Chen Y, Jiang H, Zhang J#. Mechanism for the Autophosphorylation of CheA Histidine Kinase: QM/MM Calculations. J Phys Chem B,2011;115:11895-11901
31、Liu X, Su X, Wang F, Huang Z, Wang Q, Li Z, Zhang R, Wu L, Pan Y, Chen Y, Zhuang H, Chen G, Shi T, Zhang J#. ODORactor: a web server for deciphering olfactory coding. Bioinformatics,2011;27:2302-2303
32、Huang Z, Zhu L, Cao Y, Wu G, Liu X, Chen Y, Wang Q, Shi T, Zhao Y, Wang Y, Li W, Li Y, Chen H, Chen G, Zhang J#. ASD: a comprehensive database of allosteric proteins and modulators. Nucleic Acids Res,2011;39:663-669
33、Lin P, Hu T, Hu J, Yu W, Han C, Zhang J*, Qin G, Yu K, G?tz F, Shen X, Jiang H, Qu D. Characterization of peptide deformylase homologues from Staphylococcus epidermidis. Microbiology,2010;156:3194-3202
34、Liu H, Shen Q, Zhang J#, Fu W. Evaluation of various inverse docking schemes in multiple targets identification. J Mol Graph Model,2010;16:1053-1061
35、Zhao Y, Lu X, Yang CY, Huang Z, Fu W, Hou T, Zhang J#. Computational Modeling Toward Understanding Agonist Binding on Dopamine 3. J Chem Inf Model,2010;50:1633-1643
36、Chen J, Bai L, Bernard D, Nikolovska-Coleska Z, Gomez C, Zhang J#, Yi H, Wang S. Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors. ACS Med Chem Lett,2010;1:85-89
37、Qin F, Chen Y, Wu M, Li Y, Zhang J#, Chen HF. Induced Fit or Conformational Selection for RNA/U1A folding. RNA,2010;16:1053-1061
38、Chen Y, He YJ, Wu M, Yan G, Li Y, Zhang J#, Chen HF. Insight into the Stability of Cross-β Amyloid Fibril from Molecular Dynamics Simulation. Biopolymers,2010;93:578-586
39、Dong MX, Zhang J#, Peng XQ, Lu H, Yun LH, Jiang S, Dai QY. Tricyclononene carboxamide derivatives as novel anti-HIV-1 agents. Eur J Med Chem,2010;45:4096-4103
40、Jian Zhang, Chenjing Li, Ting Shi, Kaixian Chen, Xu Shen, Hualiang Jiang.. Glucokinase Is a Determinant for Glucose Phosphorylation: Implication for the Atomic Mechanism of Glucokinase Catalysis. PLOS ONE,2009;4:e6304
41、Cindy Gomez, Longchuan Bai, Jian Zhang, Zaneta Nikolovska-Coleska, Jianyong Chen, Han Yi, Shaomeng Wang. Design, Synthesis and Evaluation of Peptidomimetics Containing Freidinger Lactams as STAT3 Inhibitors. Bioorg. Med. Chem. Lett,2009;19:1733-1736
42、Shangary S, Qin D, McEachern D, Liu M, Miller RS, Qiu S, Nikolovska-Coleska Z, Ding K, Wang G, Chen J, Bernard D, Jian Zhang, Lu Y, Gu Q, Shah RB, Pienta KJ, Ling X, Kang S, Guo M, Sun Y, Yang D, Shaomeng Wang.. Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition. Proc. Natl. Acad. Sci. USA.,2008;105:3933-3938.
43、Shuai Chen, Tiancen Hu, Jian Zhang*, Jing Chen, Kaixian Chen, Hualiang Jiang, Xu Shen. Mutation of Gly11 on the Dimer Interface Results in the Complete Crystallographic Dimer Dissociation of SARS-CoV 3CLpro: Crystal Structure in Conjunction with Molecular Dynamics Simulations. J. Biol. Chem.,2008;283:554-564.
44、Yu XL, Hu T, Du JM, Yang XM, Jian Zhang, Yang B, Shen X, Zhang Z, Zhong WD, Wen N, Ding JP, Jiang H, Zhu P, Chen ZN. Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion. J. Biol. Chem.,2008;283:18056-18065.
45、Shuai Chen, Jian Zhang, Lili Chen, Kaixian Chen, Hualiang Jiang, Xu Shen. Residues on the Dimer Interface of SARS Coronavirus 3C-like Protease: Dimer Stability Characterization and Enzyme Catalytic Activity Analysis.. The Journal of Biochemistry,2008;143:552-536
46、Chen Jianyong, Collins Gregory, Jian Zhang, Chao-Yie Yang, Levant Beth, Woods James, Shaomeng Wang.. Design, Synthesis and Evaluation of a Potent and Selective Ligand for the Dopamine 3 (D3) Receptor with a Novel In vivo Behavioral Profile.. J. Med. Chem.,2008;51:5905-5908
47、Juwen Shen, Jian Zhang*, Xiaomin Luo, Weiliang Zhu, Kunqian Yu, Yixue Li, Hualiang Jiang. Predicting protein-protein interactions based only on sequences information.. Proc. Natl. Acad. Sci. USA.,2007;104:4337-4341
48、Cong Han, Jian Zhang*, Lili Chen, Kaixian Chen, Xu Shen, Hualiang Jiang. Discovery of Helicobacter pylori shikimate kinase inhibitors: bioassay and molecular modeling. Bioorg. Med. Chem.,2007;15:656-662
49、Deju Ye, Jian Li, Jian Zhang, Hong Liu, Hualiang Jiang. Simultaneous stereoselective 4-amination with cyclic secondary amines and 2-O-deacetylation of peracetylated sialic acid derivatives.. Tetrahedron Letter,2007;48:4023-4027
50、Aijun Lu, Jian Zhang, Xiaojin Yin, Xiaomin Luo, Hualiang Jiang. Farnesyltransferase pharmacophore model derived from diverse classes of inhibitors. Bioorg. Med. Chem. Lett,2007;15:243-249.
51、Min Huang, Heyong Gao, Yi Chen, Hong Zhu, Yujun Cai, Xiongwen Zhang, Zehong Miao, Hualiang Jiang. Chimmitecan, a Novel 9-Substituted Camptothecin, with Excellent Improvement in Anti-cancer Pharmacological Profiles both In Vitro and In Vivo. Clincial Cancer Research,2007;6:484-495
52、Zhiqiang Qin, Baoleri Lee, Lei Yang, Jian Zhang, Xiaomei Yang, Di Qu, Hualiang Jiang, Soeren Molin. Anti-microbial Activities of YycG Histidine Kinase Inhibitors against Staphylococcus epidermidis Biofilms. FEMS Microbiology Letters,2007;273:149-156
53、Jian Zhang, Chenjing Li, Kaixian Chen, Weiliang Zhu, Xu Shen, Hualiang Jiang. Conformational transition pathway in the allosteric process of human glucokinase. Proc. Natl. Acad. Sci. USA.,2006;103:13368-13373.
54、Jian Li, Jian Zhang*, Jing Chen, Xiaomin Luo, Weiliang Zhu, Jianhua Shen, Hong Liu, Xu Shen, Hualiang, Jiang. An Effective Strategy for Discovering Novel Chemical Inhibitors of Human Cyclophilin A: Focused Library Design, Virtual Screening, Chemical Synthesis and Bioassay. J. Comb. Chem.,2006;8:326-337
55、Zhiqiang Qin, Jian Zhang*, Bin Xu, Lili Chen, Yang Wu, Yuanzhu Ou, Xiaomei Yang, Xu Shen, Hualiang Jiang, Di Qu. Structure-based discovery of inhibitors of the YycG histidine kinase: New chemical leads to combat Staphylococcus epidermidis infections. BMC MICROBIOL.,2006;6:96-114
56、Jian Zhang, KunQian Yu, Weiliang Zhu, Hualiang Jiang.. Neuraminidase pharmacophore model derived from diverse classes of inhibitors. Bioorg. Med. Chem. Lett,2006;16:3009-3014.
57、Jianhua Cai, Cong Han, Tianchen Hu, Jian Zhang, Fangdao Wang, Yunqing Liu, Jianping Ding, Kaixian Chen, Jianmin Yue, Xu Shen, Hualiang Jiang. PDF Enzyme is a Potential Target for Anti-Helicobacter pylori Drugs: Reverse Docking, Enzymatic assay and X-ray Crystallography Validation. Protein Sci.,2006;15:2071-2081
58、Jian Li, Jing Chen, Chunshan Gui, Li Zhang, Yu Qin, Qiang Xu, Jian Zhang, Hong Liu, Xu Shen and Hualiang Jiang. Discovering novel chemical inhibitors of human cyclophilin A: Virtual screening, synthesis, and bioassay. Bioorg. Med. Chem,2006;14:2209-2224
59、Jian Li, Jin-zhi Tan, Li-li Chen, Jian Zhang, Xu Shen, Chang-lin Mei, Li-li Fu, Li-ping Lin, Jian Ding, Bing Xiong, Hong Liu, Xiao-min Luo, Hua-liang Jiang. Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives. . Acta Pharmacologica Sinica,2006;27:1259-1271.
60、Jian Zhang, Yechun Xu, Jianhua Shen, Xiaomin Luo, Jiagao Chen, Kaixian Chen, Weiliang Zhu, and Hualiang Jiang.. Dynamic Mechanism for the Autophosphorylation of CheA Histidine Kinase: Molecular Dynamics Simulations.. J. AM. CHEM. SOC.,2005;127:11709-11719
61、Gang Chen, Suxin Zheng, Xiaomin Luo, Jianhua Shen, Weiliang Zhu, Hong Liu, Chunshan Gui, Jian Zhang, Mingyue Zheng, Chum Mok Puah, Kaixian Chen, Hualiang Jiang.. Focused Combinatorial Library Design Based on Structural Diversity, Druglikeness and Binding Affinity Score. J. Comb. Chem.,2005;7:398-406
62、Jian Zhang, Xiao-Hui Zhu, Peng Hao, Yun-Tao Mao, Xin Sun, Le-Meng Wu, Guo-Hui Li, Xiao-Yan Qiu. Immunoglobulin G expression in lung cancer cells.. ACTA BIOCHIMICA et BIOPHYSICA SINICA .,2003;35:197-214
63、Xiaoyan Qiu, Xiaohui Zhu, Liang Zhang, Yuntao Mao, Jian Zhang, Peng Hao, Guohui Li, Peng Lv, Zhixin Li, Xin Sun, Lemeng Wu, Jie Zheng, Yuqing Deng, Chunmei Hou, Peixian Tang, Shuren Zhang and Youhui Zhang. Human Epithelial Cancers Secrete Immunoglobulin G with Unidentified Specificity to Promote Growth and Survival of Tumor Cells.. Cancer Research,2003;63:6488-6495