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上海交通大学医学院研究生导师简介 黄建

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 黄建 专业代码: 071010
性别: 专业名称: 生物化学与分子生物学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 硕士生导师 专业学位导师:
联系方式: jyhuanj@shsmu.edu.cn hj1970@hotmail.com
研究方向 (点击浏览详细信息)
肿瘤分子生物学
RNAi
社会任职
中国细胞生物学会会员,上海细胞生物学会会员
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
81171941TRBP蛋白的SUMO化修饰及其在肿瘤发生发展中的功能研究国家自然科学基金面上项目2012-01~~2015-1260万元课题负责人
No12YZ033DGCR8蛋白的SUMO化修饰及在miRNA加工中的功能研究上海市教委科研创新项目2012-01~~2014-128万元课题负责人
31071228 PTPα基因突变体激活的机制研究国家自然科学基金面上项目2011-01~~2011-128万元课题负责人
09ZR1416400一种新的蛋白质酪氨酸磷酸酶alpha基因突变体及其生物活性研究上海市自然科学基金项目2009-08~~2011-0710万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Huang J, Yan J, Zhang J, Zhu S, Wang Y, Shi T, Zhu C, Chen C, Liu X, Cheng J, Mustelin T, Feng GS, Chen G, Yu J. SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nat Commun,2012;Jun 19; 3: 911. doi: 10.1038/ncomms1919
2、Liu X, Wang Y, Sun Q, Yan J, Huang J, Zhu S, Yu J. Identification of microRNA transcriptome involved in human natural killer cell activation. Immunol Lett,2012;143(2):208-17
3、Lin X, Luo K, Lv Z, Huang J#. Beta-adrenoceptor action on pancreatic cancer cell proliferation and tumor growth in mice. Hepatogastroenterology,2012;59(114):584-8
4、Huang XY, Wang HC, Yuan Z, Huang J, Zheng Q. Norepinephrine Stimulates Pancreatic Cancer Cell Proliferation, Migration and Invasion Via ?-Adrenergic Receptor-Dependent Activation of P38/MAPK Pathway. Hepatogastroenterology,2012;May-Jun; 59(115): 889-93. doi: 10.5754/h
5、Huang J, Yao L, Xu R, Wu H, Wang M, White BS, Shalloway D, Zheng X. Activation of Src and transformation by an RPTPα splice mutant found in human tumors. EMBO J,2011;30(15):3200-11
6、Huang J, Wang H, Song Z, Lin X, Zhang C. Involvement of MAPK phosphatase-1 in dexamethasone-induced chemoresistance in lung cancer. J Chemother,2011;23(4):221-6
7、Hou C H, Huang J*, He Q Y, Zhang C N, Zhang X J and Qian R L. Involvement of Sp1/Sp3 in the activation of GATA-1 erythroid promoter in K562 cells. Cell Res,2008;18(2):302-10
8、Xu R, Zhang P, Huang J, Ge S, Lu J, Qian G. Sp1 and Sp3 regulate basal transcription of the survivin gene. Biochem Biophys Res Commun,2007;356 (1):286-92
9、Hou C H, Huang J, Qian R L. Functional analysis of multiple transcription factor sites in a regulatory element of human epsilon-globin gene. Acta Biochim Biophys Sin (Shanghai),2004;36(10):673-80
10、zhang S B, Huang J*, Zhao H, Zhang Y, Hou C H, Cheng X D, Jiang C, Li M Q, Hu J, Qian R L. The in vitro reconstitution of nucleosome and its binding patterns with HMG1/2 and HMG14/17 proteins. Cell Res,2003;13(5):351-9
11、Hou C H, Huang J, Zhang S B, Qian R L. Interactions between HMG proteins (HMG1/2 and HMG14/17) and human epsilon-globin gene promoter (epsilon-promoter). Chinese Sci Bull,2002;47(18):1543-6
12、Hou C H, Huang J, Qian R L. Identification of a NF-kappaB site in the negative regulatory element(epsilon-NRAII) of human epsilon-globin gene and its binding protein NF-kappaB p50 in the nuclei of K562 cells. Cell Res,2002;12(1):79-82


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