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上海交通大学医学院研究生导师简介 徐晨

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 徐晨 专业代码: 100101
性别: 专业名称: 人体解剖与组织胚胎学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: chenx@shsmu.edu.cn 上海市重庆南路280号,邮编:200025电话:021-64663160 或者 021-63846590转776435
研究方向 (点击浏览详细信息)
生殖健康的基础与临床研究
社会任职
上海市解剖学会副理事长
中国解剖学会理事
中国解剖学会组织胚胎学专业委员会委员
中国解剖学会医学发育生物学分会理事
中国优生学会理事
中国细胞生物学会医学细胞生物学分会理事
《Asian J Androl》编委
《Reprod Contracept》编委
《中国组织化学与细胞化学杂志》编委
《中华男科学杂志》编委
《中国组织化学与细胞化学杂志》编委
中国生殖生物学会理事
国际男科学会(ISA)会员
美国生殖研究学会(SSR)会员
美国男科学会(ASA)会员
《生理学报》常务编委
《中国男科学杂志》编委
《上海交通大学学报(医学版)》编委
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
12JC1405500miRNA-449家族与miRNA-34b/c对精子发生调节机制的研究上海市科委自然基金,重点项目2013-01~~2015-1240万元课题负责人
81270732溶脲脲原体编码蛋白线性表位鉴定及多表位肽避孕疫苗的研究国家自然科学基金2013-01~~2013-1216万元课题负责人
81070526多价精子抗原嵌合肽免疫节育疫苗的研究国家自然基金委,面上项目2011-01~~2013-1235万元课题负责人
2009JG04慢性骨盆疼痛综合征患者前列腺液的菌群研究 市计生委科研项目2009-04~~2012-033万元课题负责人
30771139小鼠青春期前后睾丸组织miRNA表达及其靶标功能的研究国家自然基金委,面上项目2008-01~~2010-1227万元课题负责人
2007JG04基于16S rDNA检测的阴道菌群研究市计生委科研项目2007-04~~2010-034万元课题负责人
30640031从溶脲脲原体中筛选免疫避孕抗原国家自然基金委,主任基金2007-01~~2007-1210万元课题负责人
06JC14046溶脲脲原体感染与节育/不育的关系及其分子机制的研究上海市科委自然基金,重点项目2006-09~~2008-0825万元课题负责人
30470909溶脲脲原体与人精子交叉反应抗原国家自然基金委,面上项目2005-01~~2007-1221万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Jianqiang Bao,Li Wang,Jianbo Lei,Yanqin Hu,Yue Liu,Hongbin Shen,Wei Yan,Chen Xu.#. STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein. . Histochem Cell Biol,2012;137(3):377-389
2、Jianqiang Bao, Ding Li, Li Wang, Jingwen Wu, Yanqin Hu, Zhugang Wang, Yan Chen, Xinkai Ca o, Cizhong Jiang, Wei Yan, Chen Xu. #. MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting the E2F transcription factor- Retinoblastoma protein (E2F-pRb) pathway.. J Biol Chem,2012;287:21686-21698
3、Aijun Zhang, Bufang Xu, Yijuan Sun, Xiaowei Lu, Ruihuan Gu, Ling Wu, Yun Feng, Chen Xu. #. Dynamic changes of histone H3 trimethylated at positions K4 and K27 in human oocytes and pre- implantation embryos.. Fertil Steril,2012;98(4):1009-1016
4、Aijun Zhang, Bufang Xu,Yijuan Sun,Xiaowei Lu,Zhihong Niu, Qian Chen, Yun Feng*, Chen Xu*.#. The effect of human cumulus cells on the maturation and developmental potential of immature oocytes in ICSI cycles. . J Assist Reprod Genet,2012;29:313–319
5、Xia X, Cai H, Qin S, Xu C. #. Histone acetylase inhibitor curcumin impairs mouse spermiogenesis-an in vitro study.. PLoS One,2012;7(11):e48673.
6、Chen SH, Li D, Xu C.#. Downregulation of Col1a1 induces differentiation in mouse spermatogonia. . Asian J Androl,2012;14(6):842-9
7、Wang L, Yuan Q, Chen S, Cai H, Lu M, Liu Y, Xu C.#. Antimicrobial Activity and Molecular Mechanism of the CRES Protein.. PLoS One,2012;7(11):e48368
8、Dong-Sheng Hou, Wen-Min Long, Jian Shen, Li-Ping Zhao, Xiao-Yan Pang,Chen Xu*. #. Characterisation of the bacterial community in expressed prostatic secretions from patients with chronic prostatitis/chronic pelvic pain syndrome and infertile men: a preliminary investigation.. Asian J Androl,2012;14:566-573.
9、Jingwen Wu, Jianqiang Bao, Li Wang, Yanqin Hu, Chen Xu.#. microRNA-184 Downregulation of Nuclear Receptor Corepressor 2 (Ncor2) in mouse spermatogenesis.. BMC Dev Biol,2011;11:64-73
10、ZHENG-MEI LV, MIN WANG,CHEN XU.#. Antifertility Characteristics of the N-terminal Region of Mouse Equatorial Segment Protein.. THE ANATOMICAL RECORD,2010;293:171-181
11、Yi Shi, Dongsheng Hou,CHEN X.#. Preliminary characterization of vaginal microbiota in healthy Chinese women using cultivation-independent methods.. J Obstet Gynaecol Res,2009;35(3):525-532
12、Min Wang, Jianli Shi, Guoyan Cheng, Yanqin Hu,CHEN X.#. The antibody against a nuclear autoantigenic sperm protein can result in reproductive failure.. Asian J Androl.,2009;11(2):183-92.
13、Min Wang, Zhenmei Lv, Jianli Shi, Yanqin Hu ,CHEN X.#. Immuno- contraceptive Potential of the Ig-Like Domain of Izumo.. Mol Reprod Dev,2009;76 :794-801
14、Jingwen Wu, Ruyao Wang, Qiangsu Guo,CHEN X.#. Expression of the retinoic acid-metabolizing enzymes RALDH2 and CYP26b1 during mouse postnatal testis development.. Asian J Androl.,2008;10(4):569-576.
15、Shao-Feng Cao, Ding Li, Qing yuan, Xin Guan, Chen XU.#. Spatial and temporal expression of c-mos in mouse testis during postnatal development.. Asian J Androl.,2008;10(2):277-285.
16、Qing Yuan, Qiansu Guo, Gail A. Cornwall, Chen Xu#, and Yifei Wang. . Age- dependent expression of the cystatin-related epididymal spermat ogenic (Cres) gene in mouse testis and epididymis.. Asian J Androl.,2007;9(3):305-311
17、Guo-Yan Cheng, Jian-Li Shi, Min Wang, Yan-Qin Hu, Chun-Meng Liu, Yi-Fei Wang, Chen Xu. #. Inhibition of acrosome reaction and sperm-zona pellucide binding by anti-human sperm membrane protein/antibody.. Asian J Androl.,2007;9(1):23-29
18、DIND LI, SHAOFENG CAO, CHEN XU. #. Polypeptide backbone derived from carboxyl terminal of mouse ZP3 inhibits sperm-zona binding.. Mol Reprod Dev,2007;74(10):1327-1336
19、Jianli Shi, Zhengmin Yang, Min Wang, Guoyan Cheng, Ding Li, Yifei Wang, Yuan cong Zhou, Xiaolong Liu, Chen Xu. #. Screening an antigen target for immuno contraceptives from cross-reactive antigens between human sperm and Ureaplasma urealyticum.. Infect Immun,2007;75(4):2004-2011
20、Xu C, Zhou ZY, Guo QS, Wang YF. . Expression of germ cell nuclear factor (GCNF) in mouse germ cells and sperm during postnatal period.. Asian J Androl.,2004;6(3):217-222
21、Zhou ZY, Xu C, Guo QS, Hu YX, Zhang YL, Wang YF. . Spatial and temporal expression of germ cell nuclear factor (GCNF) in murine epididymis.. Asian J Androl.,2004;6(1):23-28.
22、Chen Xu, Meige Lu, Qiangsu Guo, Yifei Wang. Germ cell apoptosis induced by U. urealyticum infection.. Asian J Androl.,2001;3(3): 199-204.
23、C Xu, B Poirier, N Lucchiarri, O Michel, J Chevalier, S Kaveri. Modulation ofendothelial cell function by normal polyspecific human immunoglobulins (IVIg): a possible mechanism of action in vascular diseases.. Am J Pathol,1998;153(4):1257-1266
24、XU Chen#, SUN Guangfang, ZHU Yunfeng and WANG Yifei. The correlation of Ureaplasma urealyticum infection with infertility. . andrologia,1997;29:219-226


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